VIB Group Leader meeting

Related content

• Research output

• 1H, 13C, and 15N backbone and side-chain chemical shift assignment of the staphylococcal MazF mRNA interferase

  Research output: Contribution to journal › Article › peer-review

• New bactericidal toxins homologous to ParE belonging to 3-component toxin-antitoxin systems in Escherichia coli O157:H7.

  Research output: Contribution to journal › Article › peer-review

• Molecular basis of gyrase poisoning by the addiction toxin CcdB

  Research output: Contribution to journal › Article › peer-review

• Rejuvenation of CcdB-poisoned gyrase by an intrinsically disordered protein domain

  Research output: Contribution to journal › Article › peer-review

• Crystal structure of the intrinsically flexible addiction antidote MazE.

  Research output: Contribution to journal › Article › peer-review

• Energetics of MazG structure in correlation with its regulatory function.

  Research output: Contribution to journal › Article › peer-review

• Alternative interactions define Gyrase specificity in the CcdB family

  Research output: Contribution to journal › Article › peer-review

• Purification and crystallization of Vibrio fischeri CcdB and its complexes with fragments from gyrase and CcdA

  Research output: Contribution to journal › Article › peer-review

• Crystallization of CcdB in complex with a GyrA fragment

  Research output: Contribution to journal › Article › peer-review

• Intricate interactions within the ccd plasmid addiction system

  Research output: Contribution to journal › Article › peer-review

• The ParE2-PaaA2 toxin-antitoxin complex from E. coli O157 forms a hetero-docecamer in solution and in the crystal

  Research output: Contribution to journal › Article › peer-review

• Driving Forces of Gyrase Recognition by the Addiction Toxin

  Research output: Contribution to journal › Article › peer-review

• Crystal Structure of CcdB, a Topoisomerase Poison from E. Coli

  Research output: Contribution to journal › Article › peer-review

• Structural and thermodynamic characterization of Vibrio fischeri CcdB

  Research output: Contribution to journal › Article › peer-review

• Doc of prophage P1 is inhibited by its antitoxin partner Phd though fold complementation

  Research output: Contribution to journal › Article › peer-review

• Crystallisation of CcdB

  Research output: Contribution to journal › Article › peer-review

• Energetics of structural transitions of the addiction antitoxin MazE

  Research output: Contribution to journal › Article › peer-review

• Vibrio cholerae ParE2 poisons DNA gyrase via a mechanism distinct from other gyrase inhibitors

  Research output: Contribution to journal › Article › peer-review

• Allostery and intrinsic disorder mediate transcription regulation by conditional co-operativity

  Research output: Contribution to journal › Article › peer-review

• Purification and crystallization of Phd, the antitoxin of the phd/doc operon

  Research output: Contribution to journal › Article › peer-review

• Crystallization of Doc and the Phd:Doc toxin-antitoxin complex

  Research output: Contribution to journal › Article › peer-review

• Crystallization of the Staphylococcus aureus MazF mRNA interferase

  Research output: Contribution to journal › Article › peer-review

• Recognition of the intrinsically flexible addiction antidote MazE by a dromedary single domain antibody fragment. Structure, thermodynamics of binding, stability and influence on interactions with DNA

  Research output: Contribution to journal › Article › peer-review

• Projects

• Crystallography of topoisomerase inhibitors and lectins.

  Project: Fundamental

• Dynamics of toxin-antitoxin stress response networks: an interdisciplinarycomputational and in-vivo approach.

  Project: Fundamental

• Infrastructure Platform Biophysics

  Project: Fundamental

• Bacterial toxin-antitoxin modules as drug targets

  Project: Fundamental

• Structural and biochemical characterization of the S. aureus and E. coli mazEF toxin-antitoxin modules

  Project: Fundamental

• Structural biology of a plasmid addiction system.

  Project: Fundamental

• Structural basis of plasmid addiction and programmed cell death in bacteria

  Project: Fundamental

• Molecular mechanisms of intrinsically disordered proteins

  Project: Fundamental

• Structural and functional characterization of the hipBA operon of the bacterium Escherichia coli.

  Project: Fundamental

• Research Cooperation VUB - University of Ljubljana; thema - 'Structural biology and biophysics: functional interactions within toxin-antitoxin networks involved in bacterial stress response'. Structural and Thermodynamic basis of transcription regulation of the higBA TA module of Vibrio Cholerae.

  Project: Fundamental

• Outsourcing naar VUB binnen samenwerking met Prof. Ambrose Cheung.

  Project: Fundamental

• Functional and genetic analysis of the ccd addiction modules

  Project: Fundamental

• Regulatory mechanisms within the mazEF family of toxinantitoxin modules

  Project: Fundamental

• Student theses

• Zuivering en karakterizatie van het addictie toxine CcdB van Vibrio fisherii

  Student thesis: Master's Thesis

• Mechanism of action of Doc from phage P1

  Student thesis: Master-after-master

• Interactie tussen CcdB en gyrase

  Student thesis: Master's Thesis

• Karakterizatie van ccd-type plasmide addictie systemen

  Student thesis: Master's Thesis

• Molecular characterization within a ParE-containing three component of toxin-antitoxin module from Escherichia coli O157:H7

  Student thesis: Master's Thesis

• Molecular interactions in the mazEFG toxin-antitoxin module from Escherichia coli

  Student thesis: Master's Thesis

• Specificity determinants in the CcdB-GyrA complex

  Student thesis: Master-after-master

• Zuivering en karakterizatie van het ccd toxine-antidote (TA) systeem van Vibrio fisherii

  Student thesis: Master's Thesis