Projects per year
Description
Which processes and transcription factors specify the first and second lineage segregation events during human preimplantation development? Differentiation into trophectoderm (TE) cells can be initiated independently of polarity; moreover, TEAD1 and YAP1 co-localize in (precursor) TE and primitive endoderm (PrE) cells, suggesting a role in both the first and the second lineage segregation events.
Abstract
Raw data supporting "Lineage segregation in human pre-implantation embryos is specified by YAP1 and TEAD1"
Size
68.3 KB
format
.xlsx
| Date made available | 16 May 2025 |
|---|---|
| Publisher | VUB Institutional Data Repository |
Keywords
- Pregnancy
- Female
- Humans
- Mice
- Animals
- Actins/metabolism
- Blastocyst/metabolism
- Embryonic Development/physiology
- Transcription Factors/genetics
- Embryo
- Mammalian/metabolism
- TEA Domain Transcription Factors
- lineage segregation
- hippo-signalling-pathway
- human preimplantation embryo development
- polarization
- epiblast
- primitive endoderm
- trophectoderm
- inner cell mass
Format
- Format
- .ai
- .tiff
- .jpg
- .db
- .xlsx
Projects
- 1 Finished
-
FWOTM968: The search for the origin of chromosomal abnormalities in human preimplantation embryos
Sermon, K., Spits, C. & Regin, M.
1/10/19 → 31/10/23
Project: Fundamental
Research output
- 1 Article
-
Lineage segregation in human pre-implantation embryos is specified by YAP1 and TEAD1
Regin, M., Essahib, W., Demtschenko, A., Dewandre, D., David, L., Gerri, C., Niakan, K. K., Verheyen, G., Tournaye, H., Sterckx, J., Sermon, K. & Van De Velde, H., 1 Aug 2023, In: Human Reproduction. 38, 8, p. 1484-1498 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)226 Downloads (Pure)