Projects per year
Description
Datasets generated to assess protein ambiguity from different sources of structural data.
Abstract
These datasets contain annotations for protein order, disorder and ambiguity from different sources of information. From DisProt and CoDNaS a dataset was generated extracting the disorder and ambiguous labels from DisProt for disorder and folding-upon-binding regions, and the ordered labels from CoDNaS. Another dataset was manually assembled from the MFIB database (Mutual folding induced by binding), and finally a manually curated one for proteins with fold-switching regions, also labelled as ambiguous regions.
Size
100 kb
| Date made available | 3 Aug 2022 |
|---|---|
| Publisher | Frontiers in Molecular Biosciences |
| Date of data production | 1 Jan 2022 - 1 Jun 2022 |
Keywords
- Protein structures
- protein ambiguity
- protein disorder
- AlphaFold
- Machine learning
Format
- Format
- fasta
- csv
-
EU587: RNAct: Enabling proteins with RNA recognition motifs for synthetic biology and bio-analytics.
1/01/19 → 31/12/22
Project: Fundamental
Research output
- 1 Article
-
Challenges in describing the conformation and dynamics of proteins with ambiguous behavior
Roca Martinez, J., Lazar, T., Gavalda Garcia, J., Bickel, D., Pancsa, R., Dixit, B., Tzavella, K., Ramasamy, P., Sanchez Fornaris, M., Grau, I. & Vranken, W., 3 Aug 2022, In: Frontiers in Molecular Biosciences. 9, 17 p., 959956.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)46 Downloads (Pure)