Projects per year
Organization profile
Organisation profile
Diabetes mellitus is a pandemic metabolic disorder characterized by chronic hyperglycemia. The pathogenic process is the result of insulin insufficiency. Insulin is a peptide hormone produced in the beta cells of the pancreatic islets. Current diabetes treatments strive for glycemic control but fail to solve the underlying beta cell defect. This approach has increased the life expectancy and quality of most patients with diabetes but has turned diabetes into a chronic disease.
Curative strategies should aim at restoring and protecting the functional beta cell mass which in turn would selfregulate a fine-tuned glucose homeostasis. Such alternative beta cell replacement therapies could either rely on exogenous delivery of beta cells through transplantation, or on endogenous repair of the endocrine pancreas through beta cell regeneration.
The main aim of the BENE lab is to (re)generate functional beta cells.
Keywords
- beta cell
- diabetes
- cell therapy
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Profiles
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Stephanie Bourgeois
- Vrije Universiteit Brussel
- Faculty of Medicine and Pharmacy
- Clinical sciences - doctoral student
- Beta Cell Neogenesis
Person: Researcher, PhD, Doctoral student
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Sophie Coenen
- Vrije Universiteit Brussel
- Pathology/molecular and cellular medicine - Doctoral scholarschip
- Beta Cell Neogenesis
- Faculty of Medicine and Pharmacy
Person: Researcher, PhD
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Laure Degroote
- Vrije Universiteit Brussel
- Pathology/molecular and cellular medicine - Doctoral scholarschip
- Faculty of Medicine and Pharmacy
- Beta Cell Neogenesis
Person: Researcher, PhD
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Nico De Leu
- UZBrussel
- Vrije Universiteit Brussel
- Pathology/molecular and cellular medicine - Academic
- Diabetes Clinic - UZB Physician
- Beta Cell Neogenesis
Person: Professor, Physician
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Ann Demarre
- Vrije Universiteit Brussel
- Pathology/molecular and cellular medicine - Education/Research Officer
- Beta Cell Neogenesis
Person: Administrative/technical staff
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OZR3783: Bilateral cooperation within the framework of a joint doctoral project: benchfee for joint PhD VUB - KU Leuven, BOLCKMANS Lenz
9/06/21 → 8/06/25
Project: Fundamental
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AIIFUND48: EFSD/JDRF/lilly European Programme in Type 1 Diabetes Research Grant : Does pregnancy induce changes in Urinary C-peptide Creatinine Ratio (UCPCR) in women with Type 1 diabetes?
Baeyens, L.
1/11/18 → 31/01/20
Project: Fundamental
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BRGIMP11: BRIDGE: Diatype : Personalized medicine in diabetes: towards an etiology-based diagnosis and better patient care
1/01/18 → 31/03/22
Project: Applied
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fwotm766: Insulin-producing cells in Drosophila, mouse and man: A multidisciplinary approach to study and treat diabetes.
Heimberg, H., Callaerts, P. & Bussche, L.
1/10/15 → 30/06/16
Project: Fundamental
Research output
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Editorial: Emerging talents in pediatric endocrinology: 2022: Editorial on the Research Topic Emerging talents in pediatric endocrinology: 2022
Staels, W. & Levine, M. A., 8 Mar 2023, In: Frontiers in Endocrinology. 14, 2 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Serum 25-OH vitamin D in childhood obesity: a cross-sectional correlation study
Nauwynck, E. M., Lersberghe, J., Staels, W., Vanbesien, J., Verheyden, S., Rutteman, B., Anckaert, E., Weets, I., Gies, I. & De Schepper, J., 21 Jan 2023, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Absence of association between hyperuricemia and aberrant metabolic parameters in Belgian children and adolescents with overweight or obesity
Nauwynck, E. M., Vanbesien, J., Staels, W., Verheyden, S., Rutteman, B., Gies, I. & De Schepper, J., 17 Mar 2022.Research output: Unpublished contribution to conference › Poster
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A rare etiology of primary amenorrhea in a 16-year-old girl
Nauwynck, E. M., Staels, W. & De Schepper, J., 22 Oct 2022, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Clinical characterization of 6 additional cases with a ARCN1 mutation: from severe fetal presentation to a recognizable craniofacial short stature syndrome
De Rademaeker, M., Van Berkel, K., De Schepper, J., Staels, W., France, A., Boecx, N., Mortier, G. R., Meuwissen, M., Wuyts, W., Brock, S., Keymolen, K., Vantroys, E., Slegers, I., Leus, A. & Dimitrov, B., Sep 2022, p. 71. 1 p.Research output: Unpublished contribution to conference › Unpublished abstract
Activities
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Educational Course on Paediatric Bone Health and Rare Bone Diseases
Willem Staels (Participant)
29 Jun 2022 → 1 Jul 2022Activity: Participating in or organising an event › Participating in or organizing an event at an external academic organisation
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UMCOR, UMC Brussel (External organisation)
Willem Staels (Member)
2022Activity: Membership › Work on academic committees and working groups
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Seminaire d' endocrinologie pédiatrique et developpement
Jean De Schepper (Participant), Willem Staels (Participant) & Jesse Vanbesien (Participant)
17 Jan 2022 → 18 Jan 2022Activity: Participating in or organising an event › Participation in workshop, seminar
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VUB Kinderuniversiteit
Stephanie Bourgeois (Participant)
3 May 2022Activity: Participating in or organising an event › Participating in or organizing a school event
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European Islet Study Group Workshop
Stephanie Bourgeois (Participant)
13 Jun 2022 → 15 Jun 2022Activity: Participating in or organising an event › Participation in conference