Projects per year
Organisation profile
Organisation profile
In the UZ Brussel the 4 departments of Cardiology, Cardiac Surgery, the Heart Rhythm Management Center and Vascular Surgery, decided to cluster their efforts into the cluster CHVZ in 2009. The objectives were to optimalize the clinical care of patients with cardio-vascular diseases. The research group "Centrum Hart-en Vaatziekten" - CHVZ - was created in 2010 with the objective to centralize the research in 2 main research topics and to extend further the fundamental and translational research in these 2 research lines: a. Cardiac Imaging for a Better Understanding of Cardiovascular Diseases b. Ion-channel Disorders: from Genetics to the Clinic The research group CHVZ is a young group without "research tradition" at the VUB. For this reason major collaboration was realized with two other research groups to obtain the objectives of fundamental and translational research. For cardiac imaging (research line 1) a collaboration with BEFY with its Small Animal Lab was started since 2006. Objectives were to elucidate the mechanisms of drug induced valvulopathy and to understand the mechanisms leading to the evolution from aortic valve sclerosis towards aortic valve stenosis. New objectives are to explore the possibilities of using imaging techniques with the use of nanobodies to characterize the vulnerable plaque in patients with atherosclerosis. For the ion-channel disorders (research line 2) we focused initially on the clinical presentation and treatment of the disease. However, we are actually exploring the genetics of these diseases more specifically of the Brugada syndrome,and are looking for parallels in ion-channel disorders in neurology. Using cardiac imaging we will also look for morphological abnormalities in these patients and explore the potential role of these mechanical abnormalities in the clinical presentation of the disease.
Keywords
- Cardio-vascular disease
- Ion-channel disorders
- Cardiac Imaging
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Collaborations and top research areas from the last five years
Profiles
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Jean-François Argacha
- UZBrussel
- Vrije Universiteit Brussel
- Clinical sciences
- Cardio-vascular diseases
- Cardiology - UZB Physician
Person: Researcher, Professor, Physician
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Gezim Bala
- UZBrussel
- Vrije Universiteit Brussel
- Heart Rhythm Research Brussels
- Clinical sciences - Undefined
- Heartrhythmmanagement - UZB Physician
- Cardio-vascular diseases
Person: Researcher, Physician
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Rudi Beckers
- UZBrussel
- Vrije Universiteit Brussel
- Cardio-vascular diseases
- Research Group on Emergency and Disaster Medicine
- Emergency Medicine - UZB Physician
Person: Researcher, Physician
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Pedro Brugada
- UZBrussel
- Vrije Universiteit Brussel
- Heart Rhythm Research Brussels
- Clinical sciences - Undefined
- Heartrhythmmanagement - UZB Physician
- Cardio-vascular diseases
Person: Researcher, Physician
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OZR3987: Bilateral cooperation within the framework of a joint doctoral project: benchfee for joint PhD VUB - UHasselt, HOEDEMAKERS Sarah
9/05/22 → 8/05/26
Project: Fundamental
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FWOAL631: Intravascular fluorescence life-time imaging of the vulnerable plaque
Van Camp, G., Lahoutte, T. & Kuijk, M.
1/01/12 → 31/12/15
Project: Fundamental
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FWOTM385: Non-invasive detection and follow-up of toxic and drug induced valvular heart disease
Schoors, D., Droogmans, S. & Van Camp, G.
1/10/06 → 30/09/10
Project: Fundamental
Research output
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2D speckle-tracking echocardiography assessment of left atrial and left ventricular mechanics: outcomes in patients with atrial fibrillation treated with hybrid ablation and left atrial appendage surgical closure
Paparella, A. M., Pannone, L., Pedrizzetti, G., Talevi, G., Della Rocca, D. G., Sorgente, A., Kronenberger, R., Paparella, G., Overeinder, I., Bala, G., Almorad, A., Ströker, E., Sieira Rodriguez-Moret, J. A., La Meir, M., Sarkozy, A., Brugada, P., Chierchia, G. B., Gharaviri, A. & De Asmundis, C., 12 Mar 2025, In: Frontiers in Bioengineering and Biotechnology. 13, 11 p., 1538809.Research output: Contribution to journal › Article › peer-review
Open Access -
A first case of desmin-related myofibrillar myopathy due to inheritance from a confirmed mosaic asymptomatic carrier
Uyttebroeck, S., Vlaeminck, J., De Schutter, E., Cordenier, A., Wellekens, S. A., Ströker, E., De Rooms, K., Helsen, C., Hes, F. J. & Giron, P., 14 Mar 2025, (Unpublished). 1 p.Research output: Unpublished contribution to conference › Poster
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A rare case of Aerococcus urinae native valve endocarditis
Goes, S., Callebaut, K., Pierard, D., Wybo, I., De Geyter, D., Muyldermans, A., Geers, J., Kerselaers, L. & Demuyser, T., Mar 2025, In: Microbiology society. 7, 3, 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Are New Thresholds Required for the Assessment of Right Ventricular Function in Patients With and Without Tricuspid Regurgitation?
Galloo, X. & Ajmone Marsan, N., Mar 2025, In: Journal of the American Society of Echocardiography. 38, 3, p. 236-238 3 p.Research output: Contribution to journal › Article › peer-review
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Atrial fibrillation burden: Stepping beyond the categorical characterization
Doundoulakis, I., Nedios, S., Zafeiropoulos, S., Vitolo, M., Della Rocca, D. G., Kordalis, A., Shamloo, A. S., Koliastasis, L., Marcon, L., Chiotis, S., Sorgente, A., Soulaidopoulos, S., Imberti, J. F., Botis, M., Pannone, L., Gatzoulis, K. A., Sarkozy, A., Stavrakis, S., Boriani, G., Boveda, S., & 3 others , May 2025, In: Heart Rhythm. 22, 5, p. 1179-1187 9 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus)
Activities
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EACVI Teaching Course on Transthoracic Echocardiography
Bernard Cosyns (Organiser)
26 Jun 2025 → 28 Jun 2025Activity: Participating in or organising an event › Participation in conference
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Session III: advanced technologies in echocardiography – principles and applications
Bernard Cosyns (Speaker)
27 Jun 2025Activity: Talk or presentation › Talk or presentation at a conference
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EACVI HIT (External organisation)
Andreea-Iulia Motoc (Member)
1 Jan 2025 → 31 Dec 2026Activity: Membership › Membership of peer-review panel or committee
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LOK Heelkunde: toepassing van prognostische genexpressieprofielen bij melanoom
Guy Verfaillie (Organiser), Jolien Kessels (Host), Dimitri Aerden (Participant), Diedert Luc De Paep (Participant), Ward Patrick M Janssens (Participant), Susanne Knape (Participant), Natalie Kris N Poortmans (Participant), Martijn Schoneveld (Participant), Evert Valvekens (Participant), Tobias Van De Winkel (Participant), Ines Van Loo (Participant), Marian Vanhoeij (Participant), Aude Vanlander (Participant), Sarah Violon (Participant) & bart willaert (Participant)
10 Apr 2025Activity: Participating in or organising an event › Participation in workshop, seminar
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Annual Meeting BSVS 2025 - Scientific program
Erik Debing (Keynote speaker)
22 Mar 2025Activity: Talk or presentation › Talk or presentation at a conference