Projects per year
Organization profile
Organisation profile
In the UZ Brussel the 4 departments of Cardiology, Cardiac Surgery, the Heart Rhythm Management Center and Vascular Surgery, decided to cluster their efforts into the cluster CHVZ in 2009. The objectives were to optimalize the clinical care of patients with cardio-vascular diseases. The research group "Centrum Hart-en Vaatziekten" - CHVZ - was created in 2010 with the objective to centralize the research in 2 main research topics and to extend further the fundamental and translational research in these 2 research lines: a. Cardiac Imaging for a Better Understanding of Cardiovascular Diseases b. Ion-channel Disorders: from Genetics to the Clinic The research group CHVZ is a young group without "research tradition" at the VUB. For this reason major collaboration was realized with two other research groups to obtain the objectives of fundamental and translational research. For cardiac imaging (research line 1) a collaboration with BEFY with its Small Animal Lab was started since 2006. Objectives were to elucidate the mechanisms of drug induced valvulopathy and to understand the mechanisms leading to the evolution from aortic valve sclerosis towards aortic valve stenosis. New objectives are to explore the possibilities of using imaging techniques with the use of nanobodies to characterize the vulnerable plaque in patients with atherosclerosis. For the ion-channel disorders (research line 2) we focused initially on the clinical presentation and treatment of the disease. However, we are actually exploring the genetics of these diseases more specifically of the Brugada syndrome,and are looking for parallels in ion-channel disorders in neurology. Using cardiac imaging we will also look for morphological abnormalities in these patients and explore the potential role of these mechanical abnormalities in the clinical presentation of the disease.
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Network
Profiles
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Jean-François Argacha
- UZBrussel
- Vrije Universiteit Brussel
- Clinical sciences - Academic
- Cardio-vascular diseases
- Cardiology - UZB Physician
Person: Researcher, Professor, Physician
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Gezim Bala
- UZBrussel
- Vrije Universiteit Brussel
- Heartrhythmmanagement - UZB Physician
- Cardio-vascular diseases
- Medical Imaging
Person: Researcher, Physician
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Pedro Brugada
- UZBrussel
- Vrije Universiteit Brussel
- Clinical sciences - Academic
- Heartrhythmmanagement - UZB Physician
- Cardio-vascular diseases
Person: Researcher, Physician, Guest professor
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Bernard Cosyns
- UZBrussel
- Vrije Universiteit Brussel
- Clinical sciences - Academic
- Cardio-vascular diseases
- Cardiology - UZB Physician
Person: Researcher, Professor, Physician
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Erik Debing
- UZBrussel
- Vrije Universiteit Brussel
- Clinical sciences - Academic
- Cardio-vascular diseases
- Vascular surgery - UZB Physician
Person: Researcher, Professor, Physician
Projects
- 2 Finished
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FWOAL631: Intravascular fluorescence life-time imaging of the vulnerable plaque
Van Camp, G., Lahoutte, T. & Kuijk, M.
1/01/12 → 31/12/15
Project: Fundamental
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FWOTM385: Non-invasive detection and follow-up of toxic and drug induced valvular heart disease
Schoors, D., Droogmans, S. & Van Camp, G.
1/10/06 → 30/09/10
Project: Fundamental
Research output
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2021 ESC Guidelines on cardiovascular disease prevention in clinical practice
ESC Scientific Document Group , Visseren, F. L. J., Mach, F., Smulders, Y. M., Carballo, D., Koskinas, K. C., Bäck, M., Benetos, A., Biffi, A., Boavida, J-M., Capodanno, D., Cosyns, B., Crawford, C., Davos, C. H., Desormais, I., Di Angelantonio, E., Franco, O. H., Halvorsen, S., Hobbs, F. D. R., Hollander, M. & 11 others, , Feb 2022, In : European Journal of Preventive Cardiology. 29, 1, p. 5-115 111 p.Research output: Contribution to journal › Article
Open Access10 Citations (Scopus) -
2021 ESC Guidelines on cardiovascular disease prevention in clinical practice: Developed by the Task Force for cardiovascular disease prevention in clinical practice with representatives of the European Society of Cardiology and 12 medical societies With the special contribution of the European Association of Preventive Cardiology (EAPC)
ESC Scientific Document Group , 2022, In : Revista Española de Cardiología (English version). 75, 5, p. 429Research output: Contribution to journal › Article
Open Access -
Additional value of left atrium remodeling assessed by three-dimensional echocardiography for the prediction of atrial fibrillation recurrence after cryoballoon ablation
Motoc, A., Scheirlynck, E., Roosens, B., Luchian, M-L., Chameleva, H., Gevers, M., Galloo, X., von Kemp, B., de Asmundis, C., Magne, J., Droogmans, S. & Cosyns, B., May 2022, In : The International Journal of Cardiovascular Imaging. 38, 5, p. 1103-1111 9 p.Research output: Contribution to journal › Article
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Ajmaline-Induced Abnormalities in Brugada Syndrome: Evaluation With ECG Imaging
Pannone, L., Monaco, C., Sorgente, A., Vergara, P., Calburean, P-A., Gauthey, A., Bisignani, A., Kazawa, S., Strazdas, A., Mojica, J., Lipartiti, F., Al Housari, M., Miraglia, V., Rizzi, S., Sofianos, D., Cecchini, F., Osório, T. G., Paparella, G., Ramak, R., Overeinder, I. & 9 others, , 18 Jan 2022, In : Journal of the American Heart Association. 11, 2, 13 p., e024001.Research output: Contribution to journal › Article
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Author Correction: Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility
KORA-Study Group, 26 Apr 2022, In : Nature Genetics.Research output: Contribution to journal › Article
Activities
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Vaatseminarie: Phlegmasia cerulea dolens en phlegmasia alba dolens
Sophie Arts (Speaker), Erik Debing (Keynote speaker), Sarah Gallala (Contributor), Laura Anna A Kerselaers (Contributor), Karl von Kemp (Contributor), Dimitri Aerden (Contributor), Audrey Devos (Contributor)28 Jan 2022Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Look at the heart! Imaging guided treatment of CS
Bernard Cosyns (Presenter)18 Mar 2022 → 20 Mar 2022Activity: Talk or presentation › Talk or presentation at a conference
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Inherited cardiomyopathies
Caroline Weytjens (Participant)13 Jan 2022Activity: Participating in or organising an event › Participation in workshop, seminar
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Global Pfizer ARIA congress
Steven Droogmans (Chair)7 Apr 2022 → 8 Apr 2022Activity: Participating in or organising an event › Participation in workshop, seminar
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Vaatseminarie 2022
Erik Debing (Organiser)1 Jan 2022 → 31 Dec 2022Activity: Participating in or organising an event › Participation in workshop, seminar