Projects per year
Organization profile
Organisation profile
In the UZ Brussel the 4 departments of Cardiology, Cardiac Surgery, the Heart Rhythm Management Center and Vascular Surgery, decided to cluster their efforts into the cluster CHVZ in 2009. The objectives were to optimalize the clinical care of patients with cardio-vascular diseases. The research group "Centrum Hart-en Vaatziekten" - CHVZ - was created in 2010 with the objective to centralize the research in 2 main research topics and to extend further the fundamental and translational research in these 2 research lines: a. Cardiac Imaging for a Better Understanding of Cardiovascular Diseases b. Ion-channel Disorders: from Genetics to the Clinic The research group CHVZ is a young group without "research tradition" at the VUB. For this reason major collaboration was realized with two other research groups to obtain the objectives of fundamental and translational research. For cardiac imaging (research line 1) a collaboration with BEFY with its Small Animal Lab was started since 2006. Objectives were to elucidate the mechanisms of drug induced valvulopathy and to understand the mechanisms leading to the evolution from aortic valve sclerosis towards aortic valve stenosis. New objectives are to explore the possibilities of using imaging techniques with the use of nanobodies to characterize the vulnerable plaque in patients with atherosclerosis. For the ion-channel disorders (research line 2) we focused initially on the clinical presentation and treatment of the disease. However, we are actually exploring the genetics of these diseases more specifically of the Brugada syndrome,and are looking for parallels in ion-channel disorders in neurology. Using cardiac imaging we will also look for morphological abnormalities in these patients and explore the potential role of these mechanical abnormalities in the clinical presentation of the disease.
Fingerprint
Network
Profiles
-
Jean-François Argacha
- UZBrussel
- Vrije Universiteit Brussel
- Clinical sciences - Academic
- Cardio-vascular diseases
- Cardiology - UZB Physician
Person: Researcher, Physician
-
Gezim Bala
- UZBrussel
- Vrije Universiteit Brussel
- Heartrhythmmanagement - UZB Physician
- Cardio-vascular diseases
- Medical Imaging
Person: Researcher, Physician
-
Pedro Brugada
- UZBrussel
- Vrije Universiteit Brussel
- Clinical sciences - Academic
- Heartrhythmmanagement - UZB Physician
- Cardio-vascular diseases
Person: Researcher, Physician, Guest professor
-
Bernard Cosyns
- UZBrussel
- Vrije Universiteit Brussel
- Clinical sciences - Academic
- Cardio-vascular diseases
- Cardiology - UZB Physician
Person: Researcher, Professor, Physician
-
Erik Debing
- UZBrussel
- Vrije Universiteit Brussel
- Surgical clinical sciences - Academic
- Cardio-vascular diseases
- Vascular surgery - UZB Physician
Person: Researcher, Professor, Physician
Projects
- 2 Finished
-
FWOAL631: Intravascular fluorescence life-time imaging of the vulnerable plaque
Van Camp, G., Lahoutte, T. & Kuijk, M.
1/01/12 → 31/12/15
Project: Fundamental
-
FWOTM385: Non-invasive detection and follow-up of toxic and drug induced valvular heart disease
Schoors, D., Droogmans, S. & Van Camp, G.
1/10/06 → 30/09/10
Project: Fundamental
Research output
-
Comparison between superior vena cava ablation in addition to pulmonary vein isolation and standard pulmonary vein isolation in patients with paroxysmal atrial fibrillation with the cryoballoon technique
Overeinder, I., Osório, T. G., Călburean, P-A., Bisignani, A., Bala, G., Sieira, J., Ströker, E., Al Houssari, M., Mojica, J., Boveda, S., Paparella, G., Brugada, P., de Asmundis, C. & Chierchia, G-B., 15 Jan 2021, In : Journal of Interventional Cardiac Electrophysiology : An International Journal of Arrhythmias and Pacing.Research output: Contribution to journal › Article
-
Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls
Nantes Referral Center for inherited cardiac arrhythmia, Walsh, R., Lahrouchi, N., Tadros, R., Kyndt, F., Glinge, C., Postema, P. G., Amin, A. S., Nannenberg, E. A., Ware, J. S., Whiffin, N., Mazzarotto, F., Škorić-Milosavljević, D., Krijger, C., Arbelo, E., Babuty, D., Barajas-Martinez, H., Beckmann, B. M., Bézieau, S., Bos, J. M. & 31 others, , Jan 2021, In : Genetics in Medicine : Official Journal of the American College of Medical Genetics. 23, 1, p. 47-58 12 p.Research output: Contribution to journal › Article
1 Citation (Scopus) -
High parasympathetic activity as reflected by deceleration capacity predicts atrial fibrillation recurrence after repeated catheter ablation procedure
Călburean, P-A., Osório, T. G., Sieira, J., Ströker, E., Maj, R., Terasawa, M., Rizzo, A., Borio, G., Scala, O., Galli, A., Brugada, P., Chierchia, G-B. & De Asmundis, C., Jan 2021, In : Journal of Interventional Cardiac Electrophysiology. 60, 1, p. 21-29 9 p.Research output: Contribution to journal › Article
-
Long-term evolution of echocardiography parameters in Brugada syndrome patients
Scheirlynck, E., Motoc, A., De Asmundis, C., Chierchia, GB., Koulalis, J., Van Malderen, S., Chierchia, GB., Pappaert, G., Haugaa, KH., Lie, ØH., Cannaerts, E., Van Dooren, S., Brugada, P., Cosyns, B. & Droogmans, S., 8 Feb 2021, In : European Heart Journal - Cardiovascular Imaging. 22, Supplement_1Research output: Contribution to journal › Article
-
On risk stratification and its paradoxes
Brugada, P., 11 Feb 2021, In : European Heart Journal. 42, 6, p. 715-716 2 p.Research output: Contribution to journal › Article
Activities
-
39th Annual Congress BSC
Bram Roosens (Participant)13 Feb 2020 → 14 Feb 2020Activity: Participating in or organising an event › Participation in conference
-
ETALAGEBENEN BIJ SPORTERS EN JONGEREN
Erik Debing (Keynote speaker), Dimitri Aerden (Speaker), Geert Lauwers (Speaker), Annick D'Haeninck (Speaker), Lieven Dossche (Speaker), Patrick Lauwers (Contributor)26 Nov 2020Activity: Talk or presentation › Talk or presentation at a conference
-
Endovasculaire behandeling van aortapathologie
Erik Debing (Speaker)17 Sep 2020Activity: Talk or presentation › Talk or presentation at a conference
-
-