Projects per year
Organization profile
Organisation profile
Doelstellingen: The department COPR deals with teaching and research in the domain of restorative dentistry. This encompasses cariology and endodontology, fixed and removable prosthodontics and child dentistry. Research activities are in three projects: 1. corrosion and degradation of dental materials and their effect on reconstituted in vitro epithelium models: Biocompatibility of dental materials using in vitro tests'. The need for biocompatible materials implies the necessity of toxicity testing. The toxicity of a dental material can be evaluated by in vitro tests, animal experimentation including usage tests and clinical studies. In vitro studies are mainly the evaluation of cytotoxicity or genotoxicity. The two most important techniques for maintaining living materials are cell culture and organ culture. Cell and tissue cultures could be very sensitive, practical and the results are quick, cheap and quantitative. In the present study cell/material interactions are evaluated by applying dental materials in the form of soluble components or microparticular corrosion products to artificial, reconstituted oral mucosa models. Corrosion or degradation products will be obtained by exposing material samples to an artificial saliva of defined composition. After cell-material (corrosion products) interaction, changes such as morphological, viability and metabolic alteration will be specified. Complementary to this, clinical studies are performed to evaluate the long-term stability of new composite materials and adhesive amalgam restorations. 2. diagnosis and prevention of early carious and enamel erosion lesions: in cooperation with ETRO (B. Truyen) and CYTO (F. Braet): in this project new observation and diagnostic methods for early enamel lesions are tested in vitro. Using AFM (atomic force microscopy), acid-induced erosion lesions are observed in 'real-time'. The effect of topical fluoride treatment is evaluated and the results are compared with SEM and microhardness tests. Diagnostic tools for the detection of incipent caries lesions are tested using image analysis for traditional and digital X-ray images and analysis of impedance measurements. 3. quality assesment and infection control in endodontic treatment: the failure rate in endodontic treatment is a consequence of faulty technique and insufficient control of (re-) infection. In a combined in vitro/in vivo study the effect of disinfection methods and quality of the covering restauration on microbiology of the root canal are evaluated.
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Profiles
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Peter Bottenberg
- Vrije Universiteit Brussel
- Clinical sciences - Academic
- Surgical clinical sciences - Academic
- Oral Health
- Dentistry - Academic
- Dental Clinic - Academic
- Conservative Dentistry and Prosthodontics - Academic
Person: Researcher, Professor, Administrative/technical staff
Projects
- 20 Finished
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OZR3256: Bilateral cooperation within the framework of a joint doctoral project: Bench Fee for joint phd VUB_ULB, Vanhée Tania
2/03/18 → 31/12/21
Project: Fundamental
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OZR1529: 2D electrophoretic analysis of protein expression in salivarygland myoepithelial cells.
1/01/07 → 31/12/08
Project: Fundamental
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BWS05/06: Contrast-enhanced intraoral digital subtraction radiography and its application to caries diagnosis.
Truyen, B., Bottenberg, P. & Cornelis, J. P.
1/01/06 → 31/12/07
Project: Fundamental
Research output
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Prevalence, Caries, Dental Anxiety and Quality of Life in Children with MIH in Brussels, Belgium
Vanhée, T., Poncelet, J., Cheikh-Ali, S. & Bottenberg, P., 2022, In : Journal of clinical medicine. 11, 11, p. 3065Research output: Contribution to journal › Article
Open Access -
Salivary Fluoride Bioavailability after Brushing with Brazilian Red Propolis Dentifrice: A Clinical Study
Girão Júnior, F. J., Valadas, L. A. R., Bottenberg, P., Lotif, M. A. L., Rodrigues Neto, E. M., Fonseca, S. G. D. C., Bandeira, M. A. M., Squassi, A., Dantas, T. C. F. B., de Sena, N. J. C. & Fonteles, M. M. D. F., 2022, In : Evidence-Based Complementary and Alternative Medicine. 2022, 6148137.Research output: Contribution to journal › Article
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Anxiété dentaire en dentisterie pédiatrique: Analyse du choix thérapeutique en fonction de l'indication
Vanhée, T., Dragan, A., Bottenberg, P., Loeb, I. & Vanden Abbeele, A., 2021, In : Revue francophone d'odontologie pédiatrique. 16, 2, p. 90-96 7 p.Research output: Contribution to journal › Article
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Associations between obesity, dental caries, erosive tooth wear and periodontal disease in adolescents: a case-control study
Marro, F., De Smedt, S., Rajasekharan, S., Martens, L., Bottenberg, P. & Jacquet, W., Feb 2021, In : EUROPEAN ARCHIVES OF PAEDIATRIC DENTISTRY. 22, 1, p. 99-108 10 p.Research output: Contribution to journal › Article
4 Citations (Scopus) -
Behavior of Children during Dental Care with Rubber Dam Isolation: A Randomized Controlled Study
Vanhée, T., Tassignon, C., Porta, P., Bottenberg, P., Charles, T. & Vanden Abbeele, A., 4 Aug 2021, In : Dentistry journal. 9, 8, 8 p., 89.Research output: Contribution to journal › Article
Open AccessFile66 Downloads (Pure)
Activities
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Joint EFP-ORCA Workshop The Boundaries between Caries and Periodontal Diseases
Peter Bottenberg (Participant)6 Nov 2016 → 9 Nov 2016Activity: Participating in or organising an event › Participation in workshop, seminar
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ORCA
Peter Bottenberg (Chair)8 Jul 2016Activity: Participating in or organising an event › Participation in conference
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BMC Oral Health (Journal)
Peter Bottenberg (Peer reviewer)1 Mar 2016 → …Activity: Publication peer-review and editorial work › Publication peer-review
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International Association of Dentomaxillofacial Radiology
Peter Bottenberg (Participant)26 Aug 2015 → 29 Aug 2015Activity: Participating in or organising an event › Participation in conference
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ORCA workshop on methodologies for the determination of potentially available fluoride in toothpastes
Peter Bottenberg (Participant)4 Feb 2015 → 5 Feb 2015Activity: Participating in or organising an event › Participation in workshop, seminar
Equipment
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Zaag en polijstuitrusting voor harde weefsels en materialen
Conservative Dentistry and ProsthodonticsFacility/equipment: Equipment