Projects per year
Organization profile
Organisation profile
The In Vitro Toxicology and Dermato-cosmetology (IVTD) research group of the Vrije Universiteit Brussel (VUB) constitutes a hub for many promising R&D projects within a broad scientific scope. They all share one common goal, namely an improvement of human health and safety. We achieve this by:
- Developing robust and human-relevant liver-based in vitro models to discriminate between safe and toxic drug candidates, and consequently reduce human exposure to liable products and safety-related drug attrition.
- Elucidating mechanisms that underlie diseases, with focus on liver, skin and recently also airways. More specific interest includes acute and chronic liver conditions, as well as different forms of allergic, autoimmune and autoinflammatory diseases.
- Identifying new drug targets and disease biomarkers, and evaluating cell- and immunotherapy strategies, eventually leading to new effective therapy options.
- Developing new analytical methods to identify toxic ingredients in e.g. illegal cosmetic and pharmaceutical products.
- Providing expert training in safety assessment, with emphasis on cosmetics and their ingredients within the context of the European legislation.
Fingerprint
Network
Profiles
-
Steven Branson
- Vrije Universiteit Brussel
- Pharmaceutical and Pharmacological Sciences - Education/Research Officer
- Experimental in vitro toxicology and dermato-cosmetology
Person: Researcher, Administrative/technical staff
Projects
-
EUAR35: H2020: CSA: TWINALT: Twinning towards excellence in alternative methods for toxicity assessment
1/09/20 → 31/08/23
Project: Applied
-
IOF3013: GEAR: Brussels Liver Research to Valorisation Alliance (B-Liver): Valorisation of VUB’s liver cell biology and toxicology expertise via a consortium focused on liver therapeutics, patient and consumer safety.
Vanhaecke, T., van Grunsven, L., De Kock, J., Vinken, M. & Reynaert, H.
1/01/20 → 31/12/24
Project: Applied
-
EU615: CONNECT-2-CLINIC: Connexin and pannexin peptidomimetics and nanobodies for the clinical treatment of liver disease.
1/01/20 → 31/12/21
Project: Fundamental
Research output
-
An exploratory approach for an oriented development of an untargeted hydrophilic interaction liquid chromatography-mass spectrometry platform for polar metabolites in biological matrices
Iturrospe, E., Da Silva, K. M., Talavera Andújar, B., Cuykx, M., Boeckmans, J., Vanhaecke, T., Covaci, A. & van Nuijs, A. L. N., 25 Jan 2021, In : Journal of Chromatography. A. 1637, 14 p., 461807.Research output: Contribution to journal › Article
-
A robust, mechanistically based in silico structural profiler for hepatic cholestasis
Firman, J. W., Pestana, C. B., Rathman, J. F., Vinken, M., Yang, C. & Cronin, M. T. D., 15 Feb 2021, In : Chemical Research in Toxicology. 34, 2, p. 641-655 15 p.Research output: Contribution to journal › Article
-
Corrigendum to: Impact of the Revised European Tobacco Product Directive on the Quality of E-cigarette Refill Liquids in Belgium
Barhdadi, S., Moens, G., Canfyn, M., Vanhee, C., Desmedt, B., Courselle, P., Rogiers, V., Vanhaecke, T. & Deconinck, E., 7 Jan 2021, In : Nicotine & tobacco research. 23, 1, p. 322-323 2 p.Research output: Contribution to journal › Article
-
Four Pistacia atlantica species (atlantica, cabulica, kurdica and mutica): a review of their botany, ethnobotany, phytochemistry and pharmacology.
Ben Ahmed, Z., Yousfi, M., Viaene, J., Dejaegher, B., Demeyer, K. & Vander Heyden, Y., 2021, In : Journal of Ethnopharmacology. 265, 113329.Research output: Contribution to journal › Article
-
Four Pistacia atlantica subspecies (atlantica, cabulica, kurdica and mutica): A review of their botany, ethnobotany, phytochemistry and pharmacology
Ben Ahmed, Z., Yousfi, M., Viaene, J., Dejaegher, B., Demeyer, K. & Heyden, Y. V., 30 Jan 2021, In : Journal of Ethnopharmacology. 265, 113329.Research output: Contribution to journal › Article
1 Citation (Scopus)
Activities
-
LSM PHD DAY
Jessie Neuckermans (Participant)30 Mar 2021Activity: Participating in or organising an event › Participation in conference
-
Webinar: the use of adverse outcome pathways for in vitro prediction of liver toxicity.
Mathieu Vinken (Speaker)10 Feb 2021Activity: Talk or presentation › Talk or presentation at a workshop/seminar
-
Evaluator associate professor position Aarhus Universitet Denmark
Mathieu Vinken (Consultant)6 Jan 2021Activity: Consultancy
-
57th EUROTOX conference
Mathieu Vinken (Organiser)12 Sep 2021 → 15 Sep 2021Activity: Participating in or organising an event › Participation in conference
-
Scientific advisor of the Dutch Research Council project "Virtual human platform for safety assessment"
Mathieu Vinken (Advisor)1 Jun 2021 → 31 May 2026Activity: Consultancy