The department is responsible for graduate teaching in Pathologic Anatomy and (post)graduate training in Experimental Pathology. The goal is to train (bio)medical students and graduates in projects which address questions in Tissue and Cell Pathology. Technical expertise is mainly in the areas of histology, immunocytochemistry, mechanisms of cell death and regeneration, in situ hybridisation, electron microscopy. Issues in surgical pathology are further addressed in the laboratory: currently, studies are undertaken on protein expression in breast carcinomas. Laboratory projects are mainly undertaken in the field of diabetes, in association with other VUB departments and/or centres collaboration with the Diabetes Research Centre (see previous pages). The department is particularly focused on the following subjects: 1. Composition of ß cell grafts for transplantation; 2. The islet pathology in diabetes and during (auto)immune destruction; 3. The regeneration of ß cells and other pancreatic cell types; 4. Genes, morphogens and markers of cell differentiation.