Projects per year
Organisation profile
Organisation profile
The department is responsible for graduate teaching in Pathologic Anatomy and (post)graduate training in Experimental Pathology. The goal is to train (bio)medical students and graduates in projects which address questions in Tissue and Cell Pathology. Technical expertise is mainly in the areas of histology, immunocytochemistry, mechanisms of cell death and regeneration, in situ hybridisation, electron microscopy. Issues in surgical pathology are further addressed in the laboratory: currently, studies are undertaken on protein expression in breast carcinomas. Laboratory projects are mainly undertaken in the field of diabetes, in association with other VUB departments and/or centres collaboration with the Diabetes Research Centre (see previous pages). The department is particularly focused on the following subjects: 1. Composition of ß cell grafts for transplantation; 2. The islet pathology in diabetes and during (auto)immune destruction; 3. The regeneration of ß cells and other pancreatic cell types; 4. Genes, morphogens and markers of cell differentiation.
Keywords
- Immunocytochemistry
- Apoptosis
- Endocrine Pancreatic Tumors
- Pancreas
- Zollinger Ellison Syndrome
- Development
- Endocrine
- Cancer
- Diabetes
- Cell Biology
- Histology
- Morphogenesis Of Endocrine Pancreas
- Morphology
- Microscopy
- Cell Growth And Differentiation
- Men-I
- Islet Cell Transplantation
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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EULLP7: Expertise ikv Life Long Learning EUROPALS.
Marichal, M. (Administrative Promotor)
27/11/09 → …
Project: Fundamental
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ADSS78858: Inkomsten medische fotografie
Bouwens, L. (Administrative Promotor)
1/10/96 → …
Project: Fundamental
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3913320020: Dia's gemaakt voor andere diensten
Marichal, M. (Administrative Promotor)
1/10/91 → …
Project: Fundamental
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ANI121: Acinar cell plasticity and its implications for pancreatic cancer development
Bouwens, L. (Administrative Promotor) & Michils, M. (Industrial Promotor)
1/10/14 → 31/03/15
Project: Fundamental
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SRP35: SRP (Groeiers): Regenerative therapy in diabetes
Bouwens, L. (Administrative Promotor) & Heimberg, H. (Co-Promotor)
1/03/14 → 28/02/19
Project: Fundamental
Research output
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Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos
Regin, M., Lei, Y., Couvreu De Deckersberg, E., Janssens, C., Huyghebaert, A., Guns, Y., Verdyck, P., Verheyen, G., Van de Velde, H., Sermon, K. & Spits, C., 9 Dec 2024, In: eLife. 12, 24 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)1 Downloads (Pure) -
Utility of icobrain for brain volumetry in multiple sclerosis clinical practice
Nguyen, A.-L., Sormani, M. P., Horakova, D., Havrdova, E. H., Barnett, M. H., De Stefano, N., Battaglini, M., Vaneckova, M., Lui, E., Gaillard, F., Desmond, P. M., Prime, H., Datta, M., Van der Walt, A., Jokubaitis, V. G., Podevyn, F., Zivadinov, R., Weinstock-Guttman, B., D'hooghe, M. B. & Nagels, G. & 11 others, , Dec 2024, In: Multiple Sclerosis and Related Disorders. 92, 10 p., 106148.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)24 Downloads (Pure) -
Association between primary graft function and 5-year outcomes of islet allogeneic transplantation in type 1 diabetes: a retrospective, multicentre, observational cohort study in 1210 patients from the Collaborative Islet Transplant Registry
Collaborative Islet Transplant Registry (CITR) Investigators study group, Piemonti, L., Keymeulen, B. & Pipeleers, D., Jun 2023, In: The Lancet Diabetes and Endocrinology. 11, 6, p. 391-401 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile46 Citations (Scopus)46 Downloads (Pure) -
Health Economic Impact of Software-Assisted Brain MRI on Therapeutic Decision-Making and Outcomes of Relapsing-Remitting Multiple Sclerosis Patients-A Microsimulation Study
Sima, D. M., Esposito, G., Van Hecke, W., Ribbens, A., Nagels, G. & Smeets, D., 27 Nov 2021, In: BRAIN SCIENCES. 11, 12, 1570.Research output: Contribution to journal › Article › peer-review
Open Access12 Citations (Scopus) -
MicroRNA-34a activation in tuberous sclerosis complex during early brain development may lead to impaired corticogenesis
Korotkov, A., Sim, N. S., Luinenburg, M. J., Anink, J. J., van Scheppingen, J., Zimmer, T. S., Bongaarts, A., Broekaart, D. W. M., Mijnsbergen, C., Jansen, F. E., Van Hecke, W., Spliet, W. G. M., van Rijen, P. C., Feucht, M., Hainfellner, J. A., Kršek, P., Zamecnik, J., Crino, P. B., Kotulska, K. & Lagae, L. & 9 others, , Oct 2021, In: Neuropathology and applied neurobiology. 47, 6, p. 796-811 16 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus)
Activities
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Annual JDRF-nPOD meeting
In 'T Veld, P. (Speaker)
23 Feb 2014 → 25 Feb 2014Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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5th annual meeting of the JDRF Network for Pancreatic organ Donors with Diabetes - nPOD
In 'T Veld, P. (Speaker)
10 Feb 2013 → 13 Feb 2013Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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JDRF-nPOD meeting on Human Insulitis.
In 'T Veld, P. (Speaker)
5 Nov 2013 → 6 Nov 2013Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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JDRF-nPOP meeting on Human Insulitis.
In 'T Veld, P. (Speaker)
5 Jun 2013 → 6 Jun 2013Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Diabetes Biobank
In 'T Veld, P. (Participant)
19 Sept 2013 → 20 Sept 2013Activity: Participating in or organising an event › Participation in workshop, seminar