Projects per year
Organisation profile
Organisation profile
The department FAFY is mainly developing research activities in the following domains: 1. The use of hepatocytes in culture and co-culture as a model for toxicity and biotransformation studies of xenobiotics: - Evaluation of the iso-enzyme pattern of hepatocytes in culture and co-culture; - Detoxification mechanisms of hepatocytes in cultures and co-cultures; - Biotransformation and toxicity of isobutene; - Biotransformation and toxicity of anti-epileptic drugs. 2. Dermato-cosmetics: - Efficiency measurements of dermato-cosmetic products; - Evaluation and standardisation of new and existing methodology for efficiency measurements of dermato-cosmetic products.
Keywords
- Pharmacology
Fingerprint
Dive into the research topics where Pharmaceutical and Pharmacological Sciences is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Luc Adriaenssens
- Vrije Universiteit Brussel
- Pharmaceutical and Pharmacological Sciences - Paid guest professor, Undefined
Person: Researcher, Guest professor
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Joeri Aerts
- Vrije Universiteit Brussel
- Pharmaceutical and Pharmacological Sciences
- Neuro-Aging & Viro-Immunotherapy
Person: Researcher, Professor
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Feyza Alyu Altinok
- Vrije Universiteit Brussel
- Pharmaceutical and Pharmacological Sciences - Unpaid employee
Person: Researcher
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Fardine Ameli
- Vrije Universiteit Brussel
- Pharmaceutical and Pharmacological Sciences - Doctoral scholarship
- Department of Analytical Chemistry, Applied Chemometrics and Molecular Modelling
- Faculty of Medicine and Pharmacy
Person: Researcher, PhD, Doctoral student
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Najat Aourz
- Vrije Universiteit Brussel
- Pharmaceutical and Pharmacological Sciences - Unpaid guest professor, Undefined, Education Coordinator
- Experimental Pharmacology
Person: Guest professor, Administrative/technical staff
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FWOSB199: Establishment and application of a liver-derived in vitro test platform for safety evaluation of food ingredients, food contaminants and their mixtures
Avirvarei, A.-C. (Mandate), Vinken, M. (Administrative Promotor) & Sanz Serrano, J. (CoI (Co-Promotor))
1/11/25 → 31/10/29
Project: Fundamental
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FWOTM1338: Induction and aggravation of liver steatosis and cholestasis by micro- and nanoplastics: an integrative in vitro mechanistic study
Xiftou, K. (Mandate), Vinken, M. (Administrative Promotor), Tabernilla Garcia, A. (CoI (Co-Promotor)) & Sanz Serrano, J. (CoI (Co-Promotor))
1/11/25 → 31/10/29
Project: Fundamental
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EU699: Liver Titanium Dioxide Toxicology: Investigating the Mechanisms of Liver Toxicity Induced by the Food Additive E171 (Titanium Dioxide, TiO2) Using In Vitro, In Vivo, and In Silico Approaches
Vinken, M. (Administrative Promotor) & De Paula Dias Moreira, L. (PI (Promotor, Principal Investigator))
1/10/25 → 3/09/27
Project: Fundamental
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VLIR444: REMEASURE: Reducing pharmaceutical waste through rational prescribing: A case study for PPIs
Tommelein, E. (Administrative Promotor)
1/09/25 → 31/08/27
Project: Fundamental
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VLIR446: Partnership for small-scale cultivation and processing of spirulina to fortify complementary food for children in Hawassa, Ethiopia
Mangelings, D. (Administrative Promotor)
1/09/25 → 31/08/27
Project: Fundamental
Research output
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Characterising complicated urinary tract infections (POS-cUTI): preliminary results of a multinational prospective cohort (POST-cUTI / ECRAID)
Van Laethem, J. (Contributor) & Clevenbergh, P. (Contributor), 2026, (Unpublished). 1 p.Research output: Unpublished contribution to conference › Poster
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Development and characterization of a MASH in vitro 3D human liver co-culture spheroid model
Yildiz, B., Orhan, H., Demeyer, K., Vinken, M. & Tabernilla Garcia, A., 2026, (In preparation). 1 p.Research output: Unpublished contribution to conference › Poster
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Improved variable reduction in Partial Least Squares modelling by global-minimum error reproducible Uninformative-Variable Elimination
Andries, J. P. M., Tinnevelt, G. H. & Vander Heyden, Y., 15 Feb 2026, In: Chemometrics and Intelligent Laboratory Systems. 269, 12 p., 105603.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
A benchmark concentration-based strategy for evaluating the combined effects of genotoxic compounds in TK6 cells
Sanders, J., Anthonissen, R., Johnson, G., Vanhaecke, T. & Mertens, B., Apr 2025, In: Archives of Toxicology. 99, 4, p. 1581-1589 9 p., 111284.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
A Bright Future for Photopharmaceuticals Addressing Central Nervous System Disorders. State of the Art and Challenges Toward Clinical Translation
Ganzoni, R. L. Z., Bournons, S. S., Carreira, E. M., De Bundel, D. & Smolders, I., 5 Apr 2025, In: Medicinal Research Reviews. 45, 5, p. 1323-1374 52 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus)
Activities
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The 23rd International Congress of the European Society of Toxicology In Vitro (ESTIV 2026) AI session proposal accepted
Jiang, J. (Chair)
29 Jun 2026 → 2 Jul 2026Activity: Participating in or organising an event › Participation in conference
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PhD thesis "From obesity-associated steatosis to liver cancer: the role of transcriptional, posttranslational and immune response networks in disease progression" by Ao Li (Event)
Vinken, M. (Jury)
16 Jan 2026Activity: Membership › Member of PhD committee
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Toxicology (Journal)
Matyjasiak, J. (Peer reviewer)
2025 → …Activity: Publication peer-review and editorial work › Publication peer-review
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PRISMA-symposium 2025
Shiwa, V. (Participant)
20 May 2025Activity: Participating in or organising an event › Participation in conference
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Effects of simulated microgravity and radiation on gap junctions and connexin hemichannels in the liver: can making liver cells shut up reduce hepatic damage induced by space conditions?
De Meulemeester, P. (Contributor)
2025Activity: Other › Written proposal
Equipment
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Seahorse platform: the Agilent Seahorse Flux Analyser with integrated normalization system.
Massie, A. (Infrastructure coordinator)
Pharmaceutical and Pharmacological SciencesFacility/equipment: Equipment › no e-resource/single sited
Datasets
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Additional file 1 of Incorporating ‘reason for use’ into the prescribing process of medication: a survey on the opinion of patients in Flanders, Belgium
Peeters, M. (Creator), Iturrospe, E. (Creator), Jans, D. (Creator), van Nuijs, A. L. N. (Creator) & De Loof, H. (Creator), figshare.ars, 1 Oct 2022
DOI: 10.6084/m9.figshare.21256851
Dataset
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Gene expression profiling of Fah- and Hgd-deficient mouse livers upon short-term nitisinone discontinuation
Neuckermans, J. (Creator), Claes, P. (Researcher), Heymans, A. (Researcher), Colemonts-Vroninks, H. (Project Member), Martens, G. (Project Member), Vanhaecke, T. (Supervisor) & De Kock, J. (Supervisor), NCBI Gene Expression Omnibus, 4 Apr 2023
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE225001
Dataset
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Epithelial-to-mesenchymal transition in human testicular organoids
Baert, Y. (Creator), Goossens, E. (Creator) & Madureira Silva, S. (Creator), VUB Institutional Data Repository, 19 Jun 2025
Dataset
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Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women
Goossens, E. (Creator), Madureira Silva, S. (Creator), Chalmel, F. (Creator) & Baert, Y. (Creator), VUB Institutional Data Repository, 6 Dec 2024
Dataset
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"Transcriptomics analysis of in vitro NASH models unveils potential adverse effect of elafibranor"
Marcelino Rodrigues, R. (Creator), NCBI Gene Expression Omnibus, 22 Mar 2022
Dataset