Projects per year
Organisation profile
About us
The department FAFY is mainly developing research activities in the following domains: 1. The use of hepatocytes in culture and co-culture as a model for toxicity and biotransformation studies of xenobiotics: - Evaluation of the iso-enzyme pattern of hepatocytes in culture and co-culture; - Detoxification mechanisms of hepatocytes in cultures and co-cultures; - Biotransformation and toxicity of isobutene; - Biotransformation and toxicity of anti-epileptic drugs. 2. Dermato-cosmetics: - Efficiency measurements of dermato-cosmetic products; - Evaluation and standardisation of new and existing methodology for efficiency measurements of dermato-cosmetic products.
Keywords
- Pharmacology
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Collaborations and top research areas from the last five years
Profiles
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Luc Adriaenssens
- Vrije Universiteit Brussel
- Pharmaceutical and Pharmacological Sciences - Paid guest professor, Undefined
Person: Researcher, Guest professor
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Joeri Aerts
- Vrije Universiteit Brussel
- Pharmaceutical and Pharmacological Sciences - Head Lecturer
- Neuro-Aging & Viro-Immunotherapy
Person: Researcher, Professor
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Najat Aourz
- Vrije Universiteit Brussel
- Pharmaceutical and Pharmacological Sciences - Unpaid guest professor, Education Coordinator
Person: Guest professor, Administrative/technical staff
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Gamze Ates
- Vrije Universiteit Brussel
- Pharmaceutical and Pharmacological Sciences - postdoctoral researcher, Lecturer
- Neuro-Aging & Viro-Immunotherapy
Person: Researcher, Professor
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Alexandra-Costina Avirvarei
- Vrije Universiteit Brussel
- Pharmaceutical and Pharmacological Sciences - External employee
- Faculty of Medicine and Pharmacy
Person: Researcher, PhD
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FWOSBO74: SBO: EVOSens: an evolutive therapy development platform for inherited metabolic disorders of the liver using metabolite responsive biosensors
De Kock, J. (Administrative Promotor) & Vanhaecke, T. (CoI (Co-Promotor))
1/10/26 → 30/09/30
Project: Applied
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VLAIM11: Innovation mandate: Senserna: a sensor-enabled evolution-driven drug discovery platform for RNA-based therapeutics to treat inherited metabolic diseases
De Kock, J. (Administrative Promotor), Crispeels, T. (CoI (Co-Promotor)) & Lequeue, S. (Mandate)
1/10/26 → 30/09/28
Project: Applied
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FWOTM1362: RADICAL | RADio- and Immunosensitisation by disruption of melanogenesis in CAncerous meLanocytes
Ertveldt, T. (Mandate), Devoogdt, N. (Administrative Promotor), Dufait, I. (CoI (Co-Promotor)) & De Kock, J. (CoI (Co-Promotor))
1/10/26 → 30/09/29
Project: Fundamental
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OZR4458: Hepatotoxic risk assessment of environmental contaminants exposure during chemotherapy
Vinken, M. (Administrative Promotor) & Marzougui, Z. (Mandate)
1/09/26 → 28/02/29
Project: Fundamental
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EU726: Harmonizing the approach used in the European Union to perform and Report Read-Across: a LIFE project
Vanhaecke, T. (Administrative Promotor)
1/09/26 → 31/08/30
Project: Fundamental
Research output
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4-HYDROXYPHENYLPYRUVATE DIOXYGENASE VARIANTS
De Kock, J. (Inventor), Neuckermans, J. (Inventor), Vanhaecke, T. (Inventor), Schwaneberg, U. (Inventor) & DHOKE, G. (Inventor), 2026, Patent No. EP4720266Research output: Patent
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5PSQ-079 Clinical pharmacists’ perspectives on recording drug hypersensitivities in patient health records: implications for patient safety
Shiwa, V., El Haddadi, W. (Contributor) & Cornu, P. (Contributor), 18 Mar 2026, In: European journal of hospital pharmacy. 33, Suppl 1, 1 p.Research output: Contribution to journal › Meeting abstract (Journal)
Open Access -
679eTiP Integrating pharmacokinetics, body composition and physical activity to predict paclitaxel dose-limiting toxicities in breast cancer
Adriaenssens, N., De Nys, L., Wuyts, S., Awada, G., Fontaine, C., Steurbaut, S., Beckwée, D., Provyn, S., Casteele, S. V., Sutter, P.-J. D. & Vermeulen, A., 1 May 2026, In: ESMO Open. 11, 1 p.Research output: Contribution to journal › Meeting abstract (Journal)
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A combined in silico and in vitro new approach methodology for early detection of liver steatogenic chemicals
Verhoeven, A., Gadaleta, D., Isbaita, N. H. K., Jiang, J., Sanz-Serrano, J., Serrano-Candelas, E., Ortega‐Vallbona, R., Vanhaecke, T. & Vinken, M., 25 Jul 2026, In: Chemico-Biological Interactions. 435, 16 p., 112153.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)18 Downloads (Pure) -
A comparative in vitro analysis of pannexin1-targeting agents
Peeters, D., Iaculli, D., Ballet, S., Devoogdt, N., De Groof, T., Vinken, M. & Van Campenhout, R., 26 Jul 2026.Research output: Unpublished contribution to conference › Poster
Activities
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Breastfeeding Medicine (Journal)
Muyldermans, J. (Editor)
29 Apr 2026Activity: Publication peer-review and editorial work › Publication peer-review
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Journal of Pharmaceutical and Biomedical Analysis (Journal)
De Hondt, L. (Peer reviewer)
2026Activity: Publication peer-review and editorial work › Publication peer-review
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VICT3R webinar "Standardisation and reuse of data from academic in vivo studies"
Vinken, M. (Chair)
13 Jan 2026Activity: Participating in or organising an event › Participation in workshop, seminar
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npj Toxicology (Journal)
Vinken, M. (Editor)
1 Jun 2026 → 31 May 2031Activity: Publication peer-review and editorial work › Editorial activity
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Toxicology (Journal)
Jiang, J. (Editor)
7 Jan 2026 → 13 Jan 2026Activity: Publication peer-review and editorial work › Publication peer-review
Equipment
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3D Alignment Tool (3DAT): Advanced alignment tool for lithography in microfabrication of hybrid devices, to enable novel chemical, analytical, optical, and (bio)medical applications
De Malsche, W. (Infrastructure coordinator), Peeters, E. (Infrastructure coordinator), Aerts, J. (Infrastructure coordinator) & Stiens, J. (Infrastructure coordinator)
Chemical Engineering and Industrial ChemistryFacility/equipment: Equipment › no e-resource/single sited
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Brussels Metabolism Core (BruMet): an Integrated Platform for In Vitro, Ex Vivo and In Vivo Metabolic Profiling
Massie, A. (Infrastructure coordinator), De Ridder, M. (Infrastructure coordinator), De Leu, N. (Infrastructure coordinator), Hernot, S. (Infrastructure coordinator), Verhulst, S. (Infrastructure coordinator) & Staels, W. (Infrastructure coordinator)
Pharmaceutical and Pharmacological SciencesFacility/equipment: Equipment › no e-resource/single sited
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MEDAL – Multimodal Evaluation using Devices for the Assessment of dysautonomia and ambulatory bLood pressure
Steurbaut, S. (Infrastructure coordinator), Petrovic, M. (Consortium partner) & De Backer, T. (Consortium partner)
Pharmaceutical and Pharmacological SciencesFacility/equipment: Equipment › no e-resource/single sited
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Seahorse platform: the Agilent Seahorse Flux Analyser with integrated normalization system.
Massie, A. (Infrastructure coordinator)
Pharmaceutical and Pharmacological SciencesFacility/equipment: Equipment › no e-resource/single sited
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Ultrahigh Pressure Liquid Chromatograph - Triple Quadrupole Mass Spectrometer for targeted analysis in complex matrices
Van Eeckhaut, A. (Infrastructure coordinator), Mangelings, D. (Infrastructure coordinator), Tommelein, E. (Infrastructure coordinator), De Waele, E. (Infrastructure coordinator) & Vander Heyden, Y. (Infrastructure coordinator)
Pharmaceutical and Pharmacological SciencesFacility/equipment: Equipment › no e-resource/single sited
Datasets
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Additional file 1 of Incorporating ‘reason for use’ into the prescribing process of medication: a survey on the opinion of patients in Flanders, Belgium
Peeters, M. (Creator), Iturrospe, E. (Creator), Jans, D. (Creator), van Nuijs, A. L. N. (Creator) & De Loof, H. (Creator), figshare.ars, 1 Oct 2022
DOI: 10.6084/m9.figshare.21256851
Dataset
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Gene expression profiling of Fah- and Hgd-deficient mouse livers upon short-term nitisinone discontinuation
Neuckermans, J. (Creator), Claes, P. (Researcher), Heymans, A. (Researcher), Colemonts-Vroninks, H. (Project Member), Martens, G. (Project Member), Vanhaecke, T. (Supervisor) & De Kock, J. (Supervisor), NCBI Gene Expression Omnibus, 4 Apr 2023
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE225001
Dataset
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Antioxidant, neuroprotective, and neuroblastoma cells (SH-SY5Y) differentiation effects of melanins and arginine-modified melanins from Daedaleopsis tricolor and Fomes fomentarius.
Nguyen, H. A. T. (Creator), Phu Ho, T. (Creator), Mangelings, D. (Creator), Van Eeckhaut, A. (Creator), Vander Heyden, Y. (Creator) & Tran, H. (Creator), Zenodo, 2024
Dataset
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GSE241069: Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals
Thienpont, A. (Creator), Gene Expression Omnibus (GEO), Mar 2024
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE241069
Dataset
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Effects of acute and chronic disease on cell junctions in mouse liver
Van Campenhout, R. (Creator) & Vinken, M. (Supervisor), EXCLI Journal, 2023
Dataset