Projects per year
Organisation profile
Organisation profile
MICH develops research in the following areas: 1. Fundamental research on the replication cycle of poliovirus, research concentrates on the first steps of the cycle (adsorption, uncoating) and the last step (assembly); 2. Development of new poliovaccines (also biotech vaccines); 3. Fundamental research on antiviral compounds (in collaboration with Janssen Research Foundation); 4. Viruses on the origin of multiple sclerosis?; 5. Theiler murine encephalitis virus (TMEV), a mouse model for multiple sclerosis.
Keywords
- Poliovirus
- Antibodies
- Vaccinology
- Vaccin
- Picornavirus
- Uncoating
- Antiviral Compounds
- Neutralisation
- Assembly
- Stabilizers
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Collaborations and top research areas from the last five years
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ADSP58: Sponsoring voor het EULLP2/PHARMINE project.
Rombaut, B. & De Paepe, K.
21/05/10 → …
Project: Fundamental
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ADSS78891: inkomsten van inrichten lesaktiviteiten in het kader van het Master en Ph D Program
Rombaut, B. & Vrijsen, R.
1/10/91 → …
Project: Fundamental
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GIFT163: System xc- as a potential target for novel neuroprotective strategies: focus on parkinson’s disease and its psychiatric comorbidities
19/12/13 → 31/12/16
Project: Fundamental
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EULLP24: PHARIN:Competences for industrial pharmacy practice in biotechnology.
Rombaut, B. & De Paepe, K.
1/10/13 → 31/03/16
Project: Fundamental
Research output
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xCT/Slc7a11 deletion accelerates motor recovery and improves histological outcomes following cervical spinal contusion in mice
Sprimont, L., Gilloteaux, J., Bouchat, J., Massie, A. & Nicaise, C., 17 Jan 2019, Frontiers in Neuroscience, Conference Abstract: Belgian Brain Congress, Liège, 19 october 2018. 1 p.Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)
Open Access -
651.06 - The cystine/glutamate antiporter system xc- as modulator of corticostriatal neurotransmission
Massie, A., Bentea, E. M., Villers, A., Moore, C., Funk, A., O'Donovan, S. M., Verbruggen, L., Depasquale, E., Churchill, M. J., Sato, H., Ris, L., Meshul, C. K. & Mccullumsmith, R. E., 2018, Society of Neuroscience, Neuroscience 2018, San Diego, 3-7 November. 1 p.Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)
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C054 - Loss of system xc- protects against proteasomal inhibition-induced neurodegeneration in aged mice
Verbruggen, L., Bentea, E. M., Deneyer, L., Albertini, G., Hideyo, S. & Massie, A., 2018, Federation of European Neuroscience Society, 11th FENS Forum of Neuroscience, Berlin, 7-11 july 2018. 1 p.Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)
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C054 - Peripheral LPS-induced inflammation increases the susceptibility for proteasome inhibition-induced degeneration of the nigrostriatal pathway
Deneyer, L., Albertini, G., Verbruggen, L., Bentea, E. M. & Massie, A., 2018, Federation of European Neuroscience Society, 11th FENS Forum of Neuroscience, Berlin, 7-11 july 2018. 1 p.Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)
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C075 - Inflammatory signaling pathways up-regulate the cystine/glutamate antiporter system xc- in cortical murine astrocytes in vitro and in the brain in vivo
Voss, T-D., Lewerenz, J., Appelt, F., Klaus, R., Hideyo, S., Albertini, G., Smolders, I. & Massie, A., 2018, Federation of European Neuroscience Society, 11th FENS Forum of Neuroscience, Berlin, 7-11 july 2018. 1 p.Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)
Activities
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UMCOR (Event)
Ann Massie (Member)
1 Jan 2017 → …Activity: Membership › Work on academic committees and working groups
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Bi-annual scientific meeting of the Belgian Society for Neuroscience
Ellen Merckx (Participant)
31 May 2013Activity: Participating in or organising an event › Participation in workshop, seminar
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Belgian Society for Neuroscience (External organisation)
Ellen Merckx (Member)
2013 → 2014Activity: Membership › Membership of external research organisation
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Bi-annual scientific meeting of the Belgian Society for Neuroscience
Ann Massie (Organiser)
31 May 2013Activity: Participating in or organising an event › Participation in workshop, seminar
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Co-organisation Conf.: EAFP Annual Conference - Curriculum optimization, towards learning outcomes : practical experiences
Bartholomeus Rombaut (Organiser)
16 May 2013 → 18 May 2013Activity: Participating in or organising an event › Participation in conference
Equipment
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Analytische balans Sartorius
Pharmaceutical Biotechnology and Molecular BiologyFacility/equipment: Equipment
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Beta scintillatieteller Wallac
Pharmaceutical Biotechnology and Molecular BiologyFacility/equipment: Equipment
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Beta scintillatieteller Wallac system 1400
Pharmaceutical Biotechnology and Molecular BiologyFacility/equipment: Equipment
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Broedkast bacteriologisch
Pharmaceutical Biotechnology and Molecular BiologyFacility/equipment: Equipment
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Centrifuge, gekoeld MSE 238121
Pharmaceutical Biotechnology and Molecular BiologyFacility/equipment: Equipment