Projects per year
Fingerprint
Collaborations and top research areas from the last five years
Profiles
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Ekaterina Baranova
- Vrije Universiteit Brussel
- Department of Bio-engineering Sciences - postdoctoral researcher
- Structural Biology Brussels
Person: Researcher
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Eva Beke
- Vrije Universiteit Brussel
- Department of Bio-engineering Sciences - Undefined, Technical Assistant
- Structural Biology Brussels
Person: Researcher, Administrative/technical staff
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Marjolijn Berghmans
- Vrije Universiteit Brussel
- Structural Biology Brussels
- Department of Bio-engineering Sciences - doctoral student
- Faculty of Sciences and Bioengineering Sciences
Person: Researcher, PhD
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BRGRD88: Proof of Concept 2024: Allosteric immunotherapy: novel drugs inspired by Nature
1/10/24 → 30/11/25
Project: Applied
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HERC66: 3D-CELLMAP: Unveiling complex cellular interactions in tissues through 3D super-resolution protein multiplex imaging
Movahedi, K., Rooman, I., Sermon, K., De Bundel, D., Fioravanti, A., Staels, W., Magez, S., Breckpot, K., De Kock, J., Laoui, D., Goyvaerts, C., Smolders, I., Van Ginderachter, J., Marcelino Rodrigues, R., De Leu, N., van Grunsven, L., Hernot, S., Peeters, E., Vanhaecke, T., De Veirman, K., Ruytinx, J., Van Schependom, J., Kortekaas, I. & Goossens, E.
1/05/24 → 31/05/28
Project: Fundamental
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HERC67: Exploiting plasma etching processes for micro/nanotexturing of metal surfaces to enable novel chemical, analytical, optical, and medical applications
De Malsche, W., Stiens, J., Hellemans, K., Vander Heyden, Y., Peeters, E., Hennecke, U., Ferranti, F., Maes, D. & Schelkens, P.
1/05/24 → 30/04/28
Project: Fundamental
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OZR4286: Financiering MZW OZR: DELI-SORT: MACSQuant® Tyto for sterile DELicate Immune cells SORTing
Laoui, D., Vanginderachter, J. A., Magez, S., Tuyaerts, S., Fioravanti, A., Devoogdt, N., Van der Henst, C., Raes, G., Stijlemans, B., Hadadi, E., De Trez, C., Ruytinx, J., Brunner, J., De Groof, T. & De Veirman, K.
24/04/24 → 24/04/28
Project: Fundamental
Research output
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A biosensor-based phage display selection method for automated, high-throughput Nanobody discovery
De Keyser, P., 26 Jun 2024, Biorxiv.Research output: Working paper › Preprint
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A cyclin D1 intrinsically disordered domain accesses modified histone motifs to govern gene transcription
Jiao, X., Di Sante, G., Casimiro, M. C., Tantos, A., Ashton, A. W., Quach, Y., Bhargava, D., Di Rocco, A., Pupo, C., Crosariol, M., Lazar, T., Tompa, P., Wang, C., Yu, Z., Li, Z., Zhang, Z., Vadlamudi, R., Mann, M., Skordalakes, E., Kossenkov, A. & 2 others, , 8 Jan 2024, In: Oncogenesis. 13, 1, p. 1-16 16 p., 4.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A designed ankyrin-repeat protein that targets Parkinson's disease-associated LRRK2
Dederer, V., Sanz Murillo, M., Karasmanis, E. P., Hatch, K. S., Chatterjee, D., Preuss, F., Abdul Azeez, K. R., Vu Nguyen, L., Galicia, C., Dreier, B., Plückthun, A., Versees, W., Mathea, S., Leschziner, A. E., Reck-Peterson, S. L. & Knapp, S., Jul 2024, In: Journal of Biological Chemistry. 300, 7, 14 p., 107469.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Allosteric nanobodies to study the interactions between SOS1 and RAS
Fischer, B., Uchański, T., Sheryazdanova, A., Gonzalez, S., Volkov, A. N., Brosens, E., Zögg, T., Kalichuk, V., Ballet, S., Versées, W., Sablina, A. A., Pardon, E., Wohlkönig, A. & Steyaert, J., 23 Jul 2024, In: Nature Communications. 15, 1, 8 p., 6214.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Analysis of the inter-domain orientation of tandem RRM domains with diverse linkers: connecting experimental with AlphaFold2 predicted models
Roca-Martínez, J., Kang, H-S., Sattler, M. & Vranken, W., 1 Mar 2024, In: NAR genomics and bioinformatics. 6, 1, 16 p., lqae002.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)
Activities
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Department of Bio-engineering Sciences (Organisational unit)
Joris Messens (Member)
30 Aug 2024Activity: Membership › Member of PhD committee
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GRC Thiol-Based Redox Regulation and Signaling
Joris Messens (Participant)
14 Jul 2024 → 19 Jul 2024Activity: Participating in or organising an event › Participation in conference
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Identification and characterization of nanobodies acting as molecular chaperones for glucocerebrosidase through a novel allosteric mechanism
Thomas Dal Maso (Speaker)
2024 → …Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Modeling and simulation of IDP ensembles
Tamas Lazar (Speaker)
27 Feb 2024Activity: Talk or presentation › Talk or presentation at a conference
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BECM cryo-EM user meeting 2024
Melina Fotiadou (Organiser)
13 Sep 2024Activity: Participating in or organising an event › Participation in conference
Equipment
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3D SUper-Resolution to cryo-Electron MIcroscopy to study nanoscale subcellular dynamics and structure that alter in Neurodegenerative Diseases - 3SURE MIND
Han Karel Remaut (Consortium partner)
Department of Bio-engineering SciencesFacility/equipment: Equipment › no e-resource/single sited
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Atomic force microscopy (AFM) nanobiotechnology based platform from reaching dynamics of single molecules to versatile materials and cell mechanics
Ronnie Willaert (Infrastructure coordinator)
Department of Bio-engineering SciencesFacility/equipment: Equipment › no e-resource/single sited
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Differential Scanning Calorimeter
Facility/equipment: Equipment
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ELIXIR Infrastructure for Data and Services to strengthen Life-Sciences Research in Flanders.
Wim Vranken (Consortium partner) & Tom Lenaerts (Consortium partner)
Facility/equipment: Equipment › e-resource/distributed
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Isothermal Titration Calorimetry
Facility/equipment: Equipment
Datasets
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Prediction of Conformational Variability for RRM proteins in inter3m data base
Gavalda Garcia, J. (Creator) & Vranken, W. (Supervisor), Zenodo, 14 Feb 2023
DOI: 10.5281/zenodo.7640833, https://doi.org/10.5281/zenodo.7640833
Dataset
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LRR domain of Roco protein from C. tepidum bound to the activating Nanobody NbRoco2
Versées, W. (Creator) & Galicia Diaz Santana, C. (Creator), Protein Data Bank, 1 May 2024
DOI: https://doi.org/10.2210/pdb8R4C/pdb
Dataset
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Roco protein from C. tepidum in the GTP state bound to the activating Nanobodies NbRoco1 and NbRoco2
Versées, W. (Creator) & Galicia Diaz Santana, C. (Creator), Protein Data Bank, 1 May 2024
DOI: https://doi.org/10.2210/pdb8R4B/pdb
Dataset
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Focused map on the Roc-COR domains of the Roco protein from C. tepidum in the GTP state bound to the activating Nanobody NbRoco1
Versées, W. (Creator) & Galicia Diaz Santana, C. (Creator), Protein Data Bank, 1 May 2024
DOI: https://doi.org/10.2210/pdb8R4D/pdb
Dataset
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Nanobodies as allosteric modulators of Parkinson's disease-associated LRRK2
Kortholt, A. (Creator), Versées, W. (Creator), Singh, R. (Creator) & Soliman, A. (Creator), Zenodo, 9 Feb 2022
DOI: 10.5281/zenodo.6028265, https://zenodo.org/record/6028265
Dataset