Projects per year
Organisation profile
Organisation profile
Topic A: Experimental in vitro toxicology: The use of isolated hepatocytes and their cultures for pharmaco- toxicological studies with focus on phase I and phase II biotransformation of xenobiotics; liver zonation of xenobiotic transformation; cell cycle and molecules affecting cell progression and cell signaling; the role of apoptosis in cell cultures; connexins and their importance in cell signaling. Topic B: Dermato-Cosmetic Sciences: Safety and efficacy of dermato-cosmetic products with focus on the technical information file and the bioengineering technology for testing, respectively. Particular attention is given to the barrier function of the skin and the lipids (ceramides) and enzymatic systems involved. Topic C: Pharmacognosy: Study of the phytochemical and pharmacological properties of medicinal plants of exotic origin e.g. treatment of dysentery and diarrhoea in traditional medicine of Lomela. . - Topic B : Dermato-cosmetics : efficiency measurements of dermato-cosmetic products : evaluation and standardisation of new and existing methodology for efficiency measurements of dermato-cosmetic
Keywords
- Cultures And Co-Cultures
- Apoptosis
- apoptosis
- Hepatocytes
- Cosmetics
- Isobutene
- Toxicity
- Saponins
- Dermato-Cosmetics
- Anti-Epileptic Drugs
- Phytochemistry
- Dermato-Cosmetic Sciences
- Drug Metabolism
- In Vitro Toxicology
- Liver Cells
- Pharmacognosy
- Human Skin
- Keratinocytes
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Collaborations and top research areas from the last five years
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GIFT78623: Service to third parties; scientific asssistance in the field of dermato-cosmetic sciences.
1/01/94 → …
Project: Fundamental
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SRP38: SRP (Groeiers): Liver-based in vitro models for toxicity testing, and translational aspects
Rogiers, V., Vanhaecke, T., Vinken, M. & Gutermuth, J.
1/03/14 → 28/02/19
Project: Fundamental
Research output
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Exposure considerations in human safety assessment: Report from an EPAA Partners' Forum
Cronin, M. T. D., Ball, N., Beken, S., Bender, H., Bercaru, O., Caneva, L., Corvaro, M., Currie, R. A., Dawson, J. L., Desert, P., Escher, S. E., Franco, A., Irizar, A., Mehta, J. M., Rogiers, V., Tremblay, R. T., Westmoreland, C. & Maxwell, G., Oct 2023, In: Regulatory Toxicology and Pharmacology. 144, 15 p., 105483.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Knowledgebase of Scientific Committee on Consumer Safety (SCCS) opinions facilitates Next Generation Risk Assessment of cosmetics
Sepehri, S., Rodrigues, R., Delagrange, M., De Kock, J., Sanctorum, A., Maushagen, J., Debruyne, C., De Troyer, O. & Vanhaecke, T., 30 Nov 2022.Research output: Unpublished contribution to conference › Poster
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RE-Place: A Unique Project Collecting Expertise on New Approach Methodologies
Van Mulders, M., Everaert, M., Liodo Missigba, N. M. A., Mertens, B. & Rogiers, V., 22 Jun 2022, In: Frontiers in Pharmacology. 13, p. 930148 12 p., 930148.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)2 Downloads (Pure) -
Comparison of temperature dependent carrier transport in FinFET and gate-all-around nanowire FET
Kim, S., Kim, J., Jang, D., Ritzenthaler, R., Parvais, B., Mitard, J., Mertens, H., Chiarella, T., Horiguchi, N. & Lee, J. W., 24 Apr 2020, In: Applied Sciences (Switzerland). 10, 8, 2979.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)97 Downloads (Pure) -
Dataset on transcriptomic profiling of cholestatic liver injury in an in vitro and in vivo animal model
Gijbels, E., Devisscher, L. & Vinken, M., Oct 2020, In: Data in Brief. 32, 106156 .Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)43 Downloads (Pure)
Activities
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TWINNING TOWARDS EXCELLENCE IN ALTERNATIVE METHODS FOR TOXICITY ASSESSMENT
Sara Sepehri (Chair), Robim Marcelino Rodrigues (Chair) & Tamara Vanhaecke (Chair)
22 Aug 2022 → 16 Sep 2022Activity: Participating in or organising an event › Participation in workshop, seminar
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Untargeted in vitro metabolomics to identify hepatotoxic modes of action
Matthias Cuykx (Speaker), Charlie Beirnaert (Contributor), Robim Marcelino Rodrigues (Contributor), Kris Laukens (Speaker), Tamara Vanhaecke (Contributor) & Adrian Covaci (Speaker)
20 Sep 2018Activity: Talk or presentation › Talk or presentation at a conference
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Kick off of Innovation Centre-3Rs (IC-3Rs)
Haaike Colemonts-Vroninks (Organiser)
25 Sep 2017Activity: Participating in or organising an event › Participation in conference
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International Gap Junction Conference 2015
Michaël Maes (Speaker)
28 Mar 2015 → 2 Apr 2015Activity: Talk or presentation › Talk or presentation at a conference
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DETECTIVE Annual Meeting
Vera Rogiers (Participant)
19 Jan 2015 → 20 Jan 2015Activity: Participating in or organising an event › Participation in workshop, seminar
Equipment
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TiS invert microscope (fluorescence)
Toxicology, Dermato-cosmetology and PharmacognosyFacility/equipment: Equipment