Toxicology, Dermato-cosmetology and Pharmacognosy

20/03/07 → …

Project: Fundamental

3943320736: Expenses TOXICO

1/08/94 → …

Project: Fundamental

GIFT78623: Service to third parties; scientific asssistance in the field of dermato-cosmetic sciences.

1/01/94 → …

Project: Fundamental

Finished

FWOTM797: Development of a human skin stem cell-derived in vitro model for the investigation of drug-induced steatosis and its mode of action.

Marcelino Rodrigues, R.

1/10/15 → 30/09/21

Project: Fundamental

SRP38: SRP (Groeiers): Liver-based in vitro models for toxicity testing, and translational aspects

Rogiers, V., Vanhaecke, T., Vinken, M. & Gutermuth, J.

1/03/14 → 28/02/19

Project: Fundamental

EU457: CONNECT: Connexin and pannexin channels as drug targets and biomarkers in acute and chronic liver disease

1/03/14 → 28/02/19

Project: Fundamental

BOR14: UZ-overdracht voor Willy Gepts Fonds. Exploration of translational potential of human skin-derived precursor cells and their in vitro generated hepatic derivatives in experimental liver disease models.

De Kock, J.

9/01/14 → 9/01/18

Project: Fundamental

IWT680: Characterisatin of connexin43 and pannexin1 as well as corresponding hemichannels as biomarkers and pharmacological targets in acute liver failure: a combined vitro-in vivo study

1/01/14 → 31/12/17

Project: Fundamental

FWOKN259: Evaluation of human skin-derived precursor cells and their in vitro generated hepatic derivatives in experimental liver disease mouse models.

De Kock, J.

1/01/14 → 31/12/14

Project: Fundamental

FWOAL732: Hemichannels as novel pharmacological targets in liver fibrosis

Vinken, M., Vanhaecke, T., Rogiers, V., Decrock, E. & Leybaert, L.

1/01/14 → 31/12/17

Project: Fundamental

FWOAL723: Characterisation of connexin43, pannexin1 and corresponding hemichannels as tissue biomarkers in acute liver failure: a combined in vitro-in vivo study

Vinken, M., Rogiers, V. & Vanhaecke, T.

1/01/14 → 31/12/17

Project: Fundamental

OZR2497: One-off infrastructure credit Prof. dr. J. Gutermuth (Co-financing via OZR Infrastructure Fund)

Rogiers, V. & Gutermuth, J.

1/06/13 → 31/05/14

Project: Fundamental

FWOAL691: Postnatal human skin progenitor cell-derived hepatocyte-like cells as potential in vitro model for hepatotoxicity screening of pharmaceuticals

Vanhaecke, T. & Vinken, M.

1/01/13 → 31/12/16

Project: Fundamental

OZR2453: Combination of toxicogenomics and humane HepaRGTM cultures for the identification of genotoxic substances

1/01/13 → 31/12/13

Project: Fundamental

ADSI352: Interne overdracht van Willy Gepts Fonds.

1/01/13 → 31/12/15

Project: Fundamental

DWTC280: Human liver disease: Study of the hepatic stem cells and their niche, and development of novel model systems

Rogiers, V., Leroux-Roels, G., Trautwein, C., Leclercq, I., Roskams, T. & Alison, M.

1/10/12 → 30/09/17

Project: Fundamental

FWOTM647: Characterization of the in vivo generated hepatic progeny from adult human skin-derived precursor cells and evaluation of their potential use for in vitro safetyscreening of pharmaceuticals and liver disease.

Rogiers, V. & De Kock, J.

1/10/12 → 1/10/17

Project: Fundamental

ADSI325: Interne overboekingen

De Paepe, K.

31/05/12 → 31/12/14

Project: Fundamental

FWOAL643: Recellularization of decellularized rad liver with human hepatic cells as a novel 3D culture model for pharmaco-toxicological research

Rogiers, V., Van Den Oord, J. & Komuta, M.

1/01/12 → 31/12/15

Project: Fundamental

OZR2266: EU-bonuskrediet type B2c voor EU FP7 project met startdatum vanaf 1/1/2011: DETECTIVE (FP7-Health-2010-Alt testing)

1/10/11 → 31/12/12

Project: Fundamental

OZR2312: EU-bonuskrediet type B2c voor EU FP7 project met startdatum vanaf 1/1/2011: HeMiBio (FP7-Health-2010-Alt.testing)

1/10/11 → 31/12/12

Project: Fundamental

OZR2219: Differentiation of human and rat derived progenitor cells into functional hepatocyte-like cells: a potential new in vitro model for early preclinical research.

van Grunsven, L. & Rogiers, V.

1/07/11 → 30/09/11

Project: Fundamental

BRGEOZ135-B: PROLONGATION: BruStem (2): Regenerative medicine of the liver using synergistic mixtures of immature or mature human hepatocytes with mesenchymal stem/progenitor cells or with hepatic stellate cells

1/06/11 → 31/05/14

Project: Fundamental

GOA78: Interplay between Epigenetic Modification Mechanisms and microRNAs - EPIGEN

Rogiers, V., Vanderkerken, K., van Grunsven, L. & VandenDriessche, T.

1/01/11 → 31/12/15

Project: Fundamental

EU375: DETECTIVE : Detection of endpoints and biomarkers of repeated dose toxicity using in vitro systems.

Rogiers, V., Vinken, M. & Vanhaecke, T.

1/01/11 → 31/12/15

Project: Fundamental

FWOKN233: The role of connexin32 and connexin43 in the control of hepatocellular homeostasis: development of a long-term primary hepatocyte culture system

Vinken, M. & Rogiers, V.

1/01/11 → 31/12/11

Project: Fundamental

OZR2149: IWT Overbruggingsbeurs (6 maanden): Titel wordt later aangevuld

1/01/11 → 28/02/11

Project: Fundamental

EU376-B: HeMiBio (zie ook EU376-A)

Rogiers, V., Vinken, M. & Vanhaecke, T.

1/01/11 → 31/12/15

Project: Fundamental

FWOTM555: Development of a differentiated hapatic in vitro system for long-term pharmaco-toxicological studies based on (epi)genetic modification of human primary hepatocytes.

1/10/10 → 30/09/14

Project: Fundamental

OZR2069: Epigenetische modificatie van genexpressie door interfenetie met histon-acetylatie en DNA methylatie in gecultiveerde rat hepatocyten.

18/04/10 → 17/10/10

Project: Fundamental

AII59: Innovative micro RNA-based differentiation strategy to develop metabolically stable long-term hepatocyte cultures, applicable in early preclinical drug research.

1/01/10 → 31/12/10

Project: Fundamental

OZR1925: Development of functional and stable hepatocyte cultures, applicable in drug research, by epigenetic modification mechanisms.

1/01/10 → 31/12/13

Project: Fundamental

FWOAL531: Innovative microRNA-based differentiation strategy to develop metabolically stable long-term hepatocyte cultures, applicable in early pre-clinical drug research.

1/01/10 → 31/12/13

Project: Fundamental

IOF842: Financiering IOF-programma - Groeier

1/03/09 → 28/02/14

Project: Fundamental

OZR1799: Zonal distribution and molecular regulation of apoptosis in organotypic hepatocyte cultures

1/01/09 → 31/12/12

Project: Fundamental

FWOAL517: Development of functional and stable hepatocyte cultures, applicable in drug research, by epigenetic modification mechanisms.

1/01/09 → 31/12/12

Project: Fundamental

FWOTM487: In vitro differentiation of human adipose tissue-derived stem cells into hepatocytes: a novel in vitro model for preclinical research of drugs.

1/10/08 → 13/04/09

Project: Fundamental

BRGEOZ135: BruStem: Regenerative medicine of the liver using synergistic mixtures of immature or mature human hepatocytes with mesenchymal stem/progenitor cells or with hepatic stellate cells.

Geerts, A., Dolle, L., Rogiers, V., Reynaert, H., van Grunsven, L. & Sokal, E.

1/06/08 → 31/05/11

Project: Fundamental

EU317: ESNATS : Embryonic stem cell-based novel alternative testing strategies

Snykers, S., Vanhaecke, T. & Rogiers, V.

1/04/08 → 30/09/13

Project: Fundamental

EU305: START-UP : Scientific and technological issues in 3Rs alternatives research in the process of drug development and union Politics.

1/03/08 → 28/02/10

Project: Fundamental

OZR1607: Elucidation of the role of connexin proteins in the control of hepatocellular homeostasis: development of a hepatocyte-based in vitro model for pre-clinical pharmaco-toxicological research

1/01/08 → 31/12/08

Project: Fundamental

FWOTM441: The establishment and optimization of functional human hepatocytes derived from postnatal progenitor/stem cells: a novel in vitro model for early preclinical testing during drug development.

Snykers, S.

1/10/07 → 30/09/10

Project: Fundamental

IWT336: Differentiatie van progenitorcellen van humane huid en vetweefsel naar functionele hepatocyten: een nieuw in vitro model voor vroeg preklinisch geneesmiddelenonderzoek.

1/01/07 → 31/12/10

Project: Fundamental

DWTC236: The hepatic progenitor cell niche under experimental conditions and in human liver disease.

Velkeniers-Hoebanckx, B., Rogiers, V., van Grunsven, L., Lazou, J., Geerts, A., Rogiers, V., Dolle, L., van Grunsven, L., Leroux-Roels, G., Roskams, T., Leclercq, I., European Partner(s), .. & European Partner(s), -.

1/01/07 → 31/03/12

Project: Fundamental

EU280: LIINTOP : optimisation of liver and intestine in vitro model for pharmacokinetics and pharmacodynamics studies.

Snykers, S., Vanhaecke, T. & Rogiers, V.

1/01/07 → 30/06/10

Project: Fundamental

OZR1519: In vitro differentation of neonatal and adult progenitor cells into hepatocyte-like cells.

1/01/07 → 30/09/07

Project: Fundamental

FWOAL399: Unraveling the pathways of permeability Barrier homeostasis: the cross-talk between corneum stress events and signalling transduction within the viable epidermis.

Roseeuw, D., De Paepe, K. & Hachem, J.

1/01/07 → 31/12/10

Project: Fundamental

EU274: CARCINOGENOMICS : development of a high throughput genomics-based test for assessing genotoxic and carcinogenic properties of chemical compounds in vitro

Vinken, M., Vanhaecke, T. & Rogiers, V.

1/11/06 → 30/04/12

Project: Fundamental

FWOTM411: Elucidation of the role of connexin proteins in the control of hepatocellular homeostasis: development of a hepatocyte-based in vitro model for pre-clinical pharmaco-toxicological research

1/10/06 → 30/09/12

Project: Fundamental

OZR1233: Geneesmiddelen met histone deacetylase inhiberende activiteit als belangrijke regulatoren van apoptose.