Toxicology, Dermato-cosmetology and Pharmacognosy

Research output

Research output per year 1970 1970 1999 2000 2001 2006 2007 2008 2009 2011 2012 2013 2014 2015 2023

• 16042 Citations
• 61 h-index
• 451 Article
• 63 Meeting abstract (Book)
• 62 Chapter
• 43 Conference paper
• 66 More
  • 18 Patent
  • 14 Meeting abstract (Journal)
  • 8 Book
  • 8 Poster
  • 6 Editorial
  • 4 Other scientific journal contribution
  • 2 Scientific review
  • 1 Commissioned report
  • 1 Other report
  • 1 Scholarly edition
  • 1 Unpublished paper
  • 1 Other contribution
  • 1 PhD Thesis

Research output per year

Research output per year

Search results

• 2023

  Exposure considerations in human safety assessment: Report from an EPAA Partners' Forum

  Cronin, M. T. D., Ball, N., Beken, S., Bender, H., Bercaru, O., Caneva, L., Corvaro, M., Currie, R. A., Dawson, J. L., Desert, P., Escher, S. E., Franco, A., Irizar, A., Mehta, J. M., Rogiers, V., Tremblay, R. T., Westmoreland, C. & Maxwell, G., Oct 2023, In: Regulatory Toxicology and Pharmacology. 144, 15 p., 105483.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Animal Testing Alternatives 100%
  • Safety 97%
  • Chemical Safety 89%
  • Exposure Assessment 57%
  4 Citations (Scopus)

  97 Downloads (Pure)
• 2022

  Knowledgebase of Scientific Committee on Consumer Safety (SCCS) opinions facilitates Next Generation Risk Assessment of cosmetics

  Sepehri, S., Rodrigues, R., Delagrange, M., De Kock, J., Sanctorum, A., Maushagen, J., Debruyne, C., De Troyer, O. & Vanhaecke, T., 30 Nov 2022.

  Research output: Unpublished contribution to conference › Poster

  • product safety 100%
  • committees 85%
  • risk assessment 82%
  • cosmetics 79%
  • ingredients 64%

• RE-Place: A Unique Project Collecting Expertise on New Approach Methodologies

  Van Mulders, M., Everaert, M., Liodo Missigba, N. M. A., Mertens, B. & Rogiers, V., 22 Jun 2022, In: Frontiers in Pharmacology. 13, p. 930148 12 p., 930148.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Databases 100%
  • Belgium 96%
  • Intellectual Property 64%
  • Computer Security 57%
  • Biological Science Disciplines 51%
  1 Citation (Scopus)

  48 Downloads (Pure)
• 2020

  Comparison of temperature dependent carrier transport in FinFET and gate-all-around nanowire FET

  Kim, S., Kim, J., Jang, D., Ritzenthaler, R., Parvais, B., Mitard, J., Mertens, H., Chiarella, T., Horiguchi, N. & Lee, J. W., 24 Apr 2020, In: Applied Sciences (Switzerland). 10, 8, 2979.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Carrier transport 100%
  • Gates (transistor) 91%
  • Nanowires 79%
  • fins 77%
  • Field effect transistors 68%
  19 Citations (Scopus)

  156 Downloads (Pure)

• Dataset on transcriptomic profiling of cholestatic liver injury in an in vitro and in vivo animal model

  Gijbels, E., Devisscher, L. & Vinken, M., Oct 2020, In: Data in Brief. 32, 106156 .

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • cholestasis 100%
  • transcriptomics 79%
  • animal models 78%
  • liver 52%
  • mice 38%
  4 Citations (Scopus)

  118 Downloads (Pure)

• Targeting gap junctional intercellular communication by hepatocarcinogenic compounds

  Leroy, K., Pieters, A., Tabernilla Garcia, A., Cooreman, A., Van Campenhout, R., Cogliati, B. & Vinken, M., 17 Aug 2020, In: Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 23, 6, p. 255-275 21 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Biological Toxin 100%
  • Gap Junctions 65%
  • Phthalate 63%
  • Pesticide 53%
  • Communication 52%
  5 Citations (Scopus)

  190 Downloads (Pure)
• 2019

  Mechanisms of drug-induced cholestasis

  Gijbels, E. & Vinken, M., 2019, In: Methods in Molecular Biology: Experimental Cholestasis Research . 1981, p. 1-14 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholestasis 100%
  • Bile Acids and Salts 54%
  • Pharmaceutical Preparations 36%
  • Bile Canaliculi 26%
  • Liver 18%
  9 Citations (Scopus)

• The effect of NTBC on the metabolic and neurocognitive profile in hereditary tyrosinemia type 1 (HT1) mouse models

  Colemonts-Vroninks, H., Yildirim, H., Martens, G., Vanhaecke, T., De Bundel, D. & De Kock, J., 25 Jun 2019.

  Research output: Unpublished contribution to conference › Poster
• 2018

  An in-depth study of high-performing strained germanium nanowires pFETs

  Mitard, J., Jang, D., Eneman, G., Arimura, H., Parvais, B., Richard, O., Van Marcke, P., Witters, L., Capogreco, E., Bender, H., Ritzenthaler, R., Mertens, H., Hikavyy, A., Loo, R., Dekkers, H., Sebaai, F., Milenin, A., Horiguchi, N., Mocuta, A., Mocuta, D., & 1 othersCollaert, N., 25 Oct 2018, 2018 IEEE Symposium on VLSI Technology, VLSI Technology 2018. Institute of Electrical and Electronics Engineers Inc., p. 83-84 2 p. 8510666. (Digest of Technical Papers - Symposium on VLSI Technology; vol. 2018-June).

  Research output: Chapter in Book/Report/Conference proceeding › Conference paper

  • Germanium 100%
  • Nanowires 92%
  • Ballistics 41%
  • Benchmarking 38%
  • Temperature 14%
  15 Citations (Scopus)

• Elafibranor restores lipogenic gene expression in a human skin stem cell-derived non-alcoholic fatty liver disease (NAFLD) model

  Boeckmans, J., Natale, A., Buyl, K., De Kock, J., Rogiers, V., Vanhaecke, T. & Marcelino Rodrigues, R., 2018, Elafibranor restores lipogenic gene expression in a human skin stem cell-derived non-alcoholic fatty liver disease (NAFLD) model. p. 354-355 2 p.

  Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)

• Genetic ablation of pannexin1 counteracts liver fibrosis in mice

  Crespo Yanguas, S., da Silva, T. C., Alves Pereira, I. V., Maes, M., Willebrords, J., Shestopalov, V. I., Goes, B., Romualdo, G. R., Barbisan, L. F., Gijbels, E., Vinken, M. & Cogliati, B., 20 Mar 2018, (Unpublished).

  Research output: Unpublished contribution to conference › Poster

  • Hepatic Stellate Cells 100%
  • Liver Cirrhosis 75%
  • Inflammasomes 73%
  • Carbon Tetrachloride 49%
  • Knockout Mice 37%

• Junctionless versus inversion-mode lateral semiconductor nanowire transistors

  Veloso, A., Matagne, P., Simoen, E., Kaczer, B., Eneman, G., Mertens, H., Yakimets, D., Parvais, B. & Mocuta, D., 3 Sept 2018, In: Journal of Physics: Condensed Matter. 30, 38, 384002.

  Research output: Contribution to journal › Article › peer-review

  • Nanowires 100%
  • Field Effect 80%
  • Semiconductor materials 71%
  • Nanowire 69%
  • Transistors 68%
  35 Citations (Scopus)

• Power-performance trade-offs for Lateral NanoSheets on ultra-scaled standard cells

  Garcia Bardon, M., Sherazi, Y., Jang, D., Yakimets, D., Schuddinck, P., Baert, R., Mertens, H., Mattii, L., Parvais, B., Mocuta, A. & Verkest, D., 25 Oct 2018, 2018 IEEE Symposium on VLSI Technology, VLSI Technology 2018. Institute of Electrical and Electronics Engineers Inc., p. 143-144 2 p. 8510633. (Digest of Technical Papers - Symposium on VLSI Technology; vol. 2018-June).

  Research output: Chapter in Book/Report/Conference proceeding › Conference paper

  • Nanosheets 100%
  • FinFET 28%
  • Set theory 14%
  • Metals 14%
  • Geometry 13%
  53 Citations (Scopus)

• Si/SiGe superlattice I/O finFETs in a vertically-stacked Gate-All-Around horizontal nanowire technology

  Hellings, G., Mertens, H., Subirats, A., Simoen, E., Schram, T., Ragnarsson, L. A., Simicic, M., Chen, S. H., Parvais, B., Boudier, D., Cretu, B., Machillot, J., Pena, V., Sun, S., Yoshida, N., Kim, N., Mocuta, A., Linten, D. & Horiguchi, N., 25 Oct 2018, 2018 IEEE Symposium on VLSI Technology, VLSI Technology 2018. Institute of Electrical and Electronics Engineers Inc., p. 85-86 2 p. 8510654. (Digest of Technical Papers - Symposium on VLSI Technology; vol. 2018-June).

  Research output: Chapter in Book/Report/Conference proceeding › Conference paper

  • Nanowires 100%
  • Field effect transistors 28%
  25 Citations (Scopus)

• TAT-Gap19 and Carbenoxolone Alleviate Liver Fibrosis in Mice

  Crespo Yanguas, S., da Silva, T. C., Alves Pereira, I. V., Willebrords, J., Maes, M., Sayuri Nogueira, M., de Castro, I. A., Leclercq, I., Romualdo, G. R., Barbisan, L. F., Leybaert, L., Cogliati, B. & Vinken, M., 12 Mar 2018, In: International Journal of Molecular Sciences. 19, 3, 17 p., 817.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • TAT-Gap19 peptide 100%
  • Stellate Crystal 72%
  • fibrosis 67%
  • Carbenoxolone 67%
  • Liver 53%
  34 Citations (Scopus)

  123 Downloads (Pure)
• 2017

  Incidence of severe critical events in paediatric anaesthesia (APRICOT): a prospective multicentre observational study in 261 hospitals in Europe

  Habre, W., Disma, N., Virag, K., Becke, K., Hansen, T. G., Joehr, M., Leva, B., Morton, N. S., Vermeulen, P. M., Zielinska, M., Boda, K., Veyckemans, F., Klimscha, W., Konecny, R., Luntzer, R., Morawk-Wintersperger, U., Neiger, F., Rustemeyer, L., Breschan, C., Frey, D., & 315 othersPlatzer, M., Germann, R., Oeding, J., Stoegermuller, B., Ziegler, B., Brotatsch, P., Gutmann, A., Mausser, G., Messerer, B., Toller, W., Vittinghoff, M., Zangl, G., Seidel-Ahyai, N., Hochhold, C., Kroess, R., Paal, P., Cnudde, S., Coucke, P., Loveniers, B., Mitchell, J., Kahn, D., Pirotte, T., Pregardien, C., Veyckemans, F., Coppens, M., De Baerdemaeker, L., De Hert, S., Heyse, B., Neckebroek, M., Parashchanka, A., Van Limmen, J., Van Den Eynde, N., Vanpeteghem, C., Wyffels, P., Lalot, M., Lechat, J-P., Stevens, F., Casaer, S., De Groote, F., De Pooter, F., De Ville, A., Gerin, M., Magasich, N., Torres, C. S., Van Deenen, D., Berghmans, J., Himpe, D., Roofthooft, E., Joukes, E., Smitz, C., Van Reeth, V., Huygens, C., Lauweryns, J., De Smet, K., Najafi, N., Poelaert, J., Van de Velde, A., Van Mossevelde, V., Bekavac, I., Butkovic, D., Litvic, D. H., Soric, I. K., Maretic, H., Moscatello, D., Popovic, L., Micic, S., Tus, I. S., Fabris, L. K., Simurina, T., Sulen, N., Kesi-Valpotic, G., Djapic, D., Zurek, J., Jureckova, L., Mackova, I., Skacel, M., Weinlichova, S., Divak, J., Frelich, M., Urbanec, R., Biskupova, V., Mixa, V., Pavlickova, J., Afshari, A., Bottger, M., Ellekvist, M. B., Johansen, M., Madsen, B. I., Nilsson, J. C., Schousboe, B. M. B., Clausen, N. G., Hansen, T. G., Steen, N. P., Ilmoja, M-L., Tonise, V., Karjagin, J., Kikas, R., Isohanni, M., Lyly, A., Takala, A., Happo, J., Kiviluoma, K., Martikainen, K., Aantaa, R., Manner, T., Vilo, S., Amory, C., Ludot, H., Lambotte, P., Busche, R., Jacqmarcq, O., Lejus, C., Corouge, J., Erb, C., Garrigue, D., Gillet, P., Laffargue, A., Lambelin, V., Le Freche, H., Peresbota, D., Richart, P., Berton, J., Chapotte, C., Colbus, L., Lehousse, T., Monrigal, J., Baujard, C., Roulleau, P., Staiti, G., Batoz, H., Bordes, M., Didier, A., Hamonic, Y., Lagarde, S., Nouette-Gaulain, K., Semjen, F., Zaghet, B., Dekens, J., Delcuze, A., Dupont, H., Legrand, A., Raffoflandreur, C., Audren, N., Camus, B., Cartal, M., Chazelet, C., Davin, I., Guillier, M., Desjeux, L., Larcher, C., Grein, E., Leclercq, M., Levitchi, R., Rosu, L., Simon, D., Zang, A., Migeon, A., Gagey, A-C., Bourdaud, N., Carre, A-C., Duflo, F., Riche, J-C., Robert, P., Druot, E., Maupain, O., Orliaguet, G., Sabau, L., Taright, H., Uhrig, L., Verchere-Montmayeur, J., Debrabant, L., Pilla, C., Podvin, A., Roth, B., Dahmani, S., Julien-Marsollier, F., Sabourdin, N., Alexandri, B., Brezac, G., de la Briere, F., Hayem, C., Lhubat, E., Mission, J. P., Remond, C., Dadure, C., Maniora, M., Marie, A., Pirat, P., Saour, A-C., Sola, C., Ecoffey, C., Wodey, E., Adam, C., Standl, T., Schindler, E., Yamamoto, T., Brackhahn, M., Eich, C. B., Guericke, H., Kindermann, P., Laschat, M., Schink, C., Wappler, F., Hoehne, C., Skordou, N., Ulrici, J., Jetzek-Zader, M., Kienbaum, P., Meyer-Treschan, T., Picker, O., Schaefer, M. S., Mielke, G., Baethge, S., Ramminger, A., Bauer, M., Bollinger, M., Hinz, J., Quintel, M., Russo, S. G., Bauer, M., Geil, D., Kortgen, A., Preussler, N-P., Hofmann, U., Raber, M., Reindl, D., Becke, K., Oppenrieder, K., Schierlinger, B., Roth, J., Funk, W., Fischer, T., Gernoth, C., Wiefelsputz, C., Volger, H., Zederer, N., Diers, A., Huber, M., Schorer, C., Weyland, A., Schwarzkopf, K., Grau, C., Roth, W., Holy, R., Mader, T., Peter, L., Supthut, H., Kuehhirt, T., Milde, A., Fiedler, F., Isselhorst, C., Grundmann, U., Pattar, A., Reinert, J., Ehm, B., Fritzsche, K., Gaebler, R., Meybohm, P., Hein, M., Guzman, I., Jokinen, J., Kranke, P., Goebel, U., Harris, S., Eisner, C., Ochsenreiter, M., Schoeler, M., Thil, E., Ellerkmann, R., Hoeft, A., Neumann, C., Weber, S., Keilhauer, J., Kloessing, J., Schramm, M., Trieschmann, U., Knauss, K., Sinner, B., Steinmann, J., Koessler, H., Kalliardou, E., Malisiova, A., Tsiotou, A., Chloropoulou, P., Chrysi, M., Iordanidou, D., Ntavlis, M., Rarosi, F., Boda, K. B., Guerin, C., Irwin, J., Magner, C., Nakhjavani, S., O'Hare, B., Galvin, D., Jamil, Y., Lesmes, C., Barak, Y., Fisher, H., Kachko, L., Katz, J., Kirilov, D., Levinzon, M., Manevich, Y., Nekrasov, K., Peled, E., Sanko, E., Schmain, D., Sheinkin, O., Simhi, E., Tarabikin, A., Trabkin, E., Yagudaev, I., Zeitlin, Y. & Zunser, I., May 2017, In: The Lancet Respiratory Medicine. 5, 5, p. 412-425

  Research output: Contribution to journal › Article › peer-review
  588 Citations (Scopus)

• Inhibition of connexin hemichannels alleviates non-alcoholic steatohepatitis in mice

  Willebrords, J., Alves Pereira, I. V., da Silva, T. C., Maes, M., Crespo Yanguas, S., Marcelino Rodrigues, R., Rogiers, V., Leclercq, I., Cogliati, B. & Vinken, M., 12 Jan 2017.

  Research output: Unpublished contribution to conference › Poster

  • connexins 100%
  • liver 40%
  • mice 39%
  • inflammation 31%
  • gap junctions 29%

• Inhibition of connexin hemichannels alleviates non-alcoholic steatohepatitis in mice

  Willebrords, J., Cogliati, B., Alves Pereira, I. V., da Silva, T. C., Crespo Yanguas, S., Maes, M., Govoni, V. M., Decrock, E., Nogueira, M. S., de Castro, I. A., Leclercq, I., Leybaert, L., Marcelino Rodrigues, R. & Vinken, M., 15 Aug 2017, In: Scientific Reports - Nature. 7, 1, 11 p., 8268.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • TAT-Gap19 peptide 100%
  • Connexins 69%
  • Fatty Liver 59%
  • Connexin 43 54%
  • Gap Junctions 38%
  33 Citations (Scopus)

• In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics

  Desmedt, B., Ates, G., Courselle, P., De Beer, J. O., Rogiers, V., Hendrickx, B., Deconinck, E. & De Paepe, K., 5 Jan 2017, In: Skin Pharmacol Physiol. 29, 6, p. 300-308 9 p., 29.

  Research output: Contribution to journal › Article › peer-review

  • hydroquinone 100%
  • Skin Absorption 94%
  • Cosmetics 84%
  • Skin 39%
  • In Vitro Techniques 31%
  9 Citations (Scopus)

• Loss of pannexin1 counteracts liver fibrosis

  Crespo Yanguas, S., da Silva, T. C., Alves Pereira, I. V., Willebrords, J., Maes, M., Shestopalov, V. I., Nogueira, M. S., de Castro, I. A., Vinken, M. & Cogliati, B., 29 Jul 2017.

  Research output: Unpublished contribution to conference › Poster

• Pannexin1 as mediator of inflammation and cell death

  Crespo Yanguas, S., Willebrords, J., Johnstone, S. R., Maes, M., Decrock, E., De Bock, M., Leybaert, L., Cogliati, B. & Vinken, M., 2017, In: Biochemica et Biophysica Acta - Molecular Cell Research. 1864, 1, p. 51-61 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Inflammation Mediators 100%
  • Cell Death 59%
  • Inflammation 46%
  • Pyroptosis 34%
  • Inflammasomes 31%
  89 Citations (Scopus)

• Role of connexin43 signaling in liver fibrosis

  Crespo Yanguas, S., da Silva, T. C., Alves Pereira, I. V., Willebrords, J., Maes, M., Leclercq, I., Cogliati, B. & Vinken, M., 28 Mar 2017.

  Research output: Unpublished contribution to conference › Poster
• 2016

  A combination of cytokines EGF and CNTF protects the functional beta cell mass in mice with short-term hyperglycaemia

  Lemper, M., De Groef, S., Stangé, G., Baeyens, L. & Heimberg, H., 18 Jun 2016, In: Diabetologia. 59, 9, p. 1948-1958 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Ciliary Neurotrophic Factor 100%
  • Epidermal Growth Factor 69%
  • Hyperglycemia 64%
  • Cytokines 44%
  • Insulin 13%
  14 Citations (Scopus)

• Antioxidant activities of Pistacia atlantica extracts modeled as a function of chromatographic fingerprints in order to identify antioxidant markers.

  Ben Ahmed, Z., Yousfi, M., Viaene, J., Dejaegher, B., Demeyer, K., Mangelings, D. & Vander Heyden, Y., 2016, In: Microchemical Journal. 128, p. 208-217 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Marker 100%
  • Antioxidant Agent 86%
  • Ferricyanide 64%
  • Gallic Acid 64%
  • Column Like Crystal 51%
  40 Citations (Scopus)

• Experimental models of liver fibrosis

  Crespo Yanguas, S., Cogliati, B., Willebrords, J., Maes, M., Colle, I., Van den Bossche, B., Pinto Marques Souza de Oliveira, C., Andraus, W., Avancini Ferreira Alves, V., Leclercq, I. & Vinken, M., 1 May 2016, In: Archives of Toxicology. 90, 5, p. 1025-1048 24 p.

  Research output: Contribution to journal › Article › peer-review

  File

  • Stellate Crystal 100%
  • Liver Cirrhosis 57%
  • Theoretical Models 50%
  • Alcohol 36%
  • Hepatitis Viruses 13%
  262 Citations (Scopus)

  1052 Downloads (Pure)

• Inhibition of Connexin43 Hemichannels Impairs Spatial Short-Term Memory without Affecting Spatial Working Memory

  Walrave, L., Vinken, M., Albertini, G., De Bundel, D., Leybaert, L. & Smolders, I. J., 2016, In: Frontiers in Cellular Neuroscience. 10, p. 288 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Connexin 43 100%
  • Spatial Memory 90%
  • Short-Term Memory 77%
  • Psychological Inhibition 66%
  • Connexins 20%
  57 Citations (Scopus)

• Inhibition of connexin hemichannels alleviates non-alcoholic steatohepatitis in mice

  Willebrords, J., Alves Pereira, I. V., da Silva, T. C., Maes, M., Crespo Yanguas, S., Cogliati, B. & Vinken, M., 12 Dec 2016.

  Research output: Unpublished contribution to conference › Poster

  • Connexins 100%
  • TAT-Gap19 peptide 89%
  • Fatty Liver 85%
  • Connexin 43 73%
  • Liver 41%

• Overview of skin whitening agents with an insight into the illegal cosmetic market in Europe

  Desmedt, B., Courselle, P., De Beer, J. O., Rogiers, V., Grosber, M., Deconinck, E. & De Paepe, K., Jun 2016, In: Journal of the European Academy of Dermatology and Venereology. 30, 6, p. 943-950 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Skin Lightening Preparations 100%
  • Bleaching Agents 90%
  • Skin Pigmentation 47%
  • Cosmetics 46%
  • kojic acid 33%
  92 Citations (Scopus)

• Poster and e-Poster at 6th Belgian Brain Council 2016: Connexin43 hemichannel inhibition exerts anticonvulsant effects against experimentally induced pharmacoresistant seizures

  Walrave, L., Pierre, A., Vinken, M., Leybaert, L. & Smolders, I., 2016.

  Research output: Unpublished contribution to conference › Poster

  • Posters 100%
  • Connexin 43 95%
  • Anticonvulsants 73%
  • Seizures 60%
  • Brain 38%

• Sources of beta cells inside the pancreas

  De Groef, S., Staels, W., Van Gassen, N., Lemper, M., Yuchi, Y., Sojoodi, M., Bussche, L., Heremans, Y., Leuckx, G., De Leu, N., Van de Casteele, M., Baeyens, L. & Heimberg, H., 6 Apr 2016, In: Diabetologia. 59, 9, p. 1834-1837 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreas 100%
  • Tissue Donors 30%
  • Cellular Reprogramming 24%
  • Induced Pluripotent Stem Cells 21%
  • Islets of Langerhans 19%
  2 Citations (Scopus)

• The Vitotox and ToxTracker assays: A two-test combination for quickand reliable assessment of genotoxic hazards

  Ates, G., Favyts, D., Hendriks, G., Derr, R., Mertens, B., Verschaeve, L., Rogiers, V. & Y. Doktorova, T., Nov 2016, In: Mutation Research. Genetic Toxicology and Environmental Mutagenesis. 810, p. 13-21 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Genotoxic 100%
  • Pharmaceutical 40%
  • Chemical Entity 35%
  • Pharmaceutical Preparations 34%
  • Cosmetic 28%
  14 Citations (Scopus)
• 2015

  Analysis of illegal peptide biopharmaceuticals frequently encountered by controlling agencies

  Vanhee, C., Janvier, S., Desmedt, B., Moens, G., Deconinck, E., De Beer, J. O. & Courselle, P., 2015, In: Talanta. 142, p. 1-10 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide 100%
  • Ultra High Performance Liquid Chromatography 19%
  • Protein 19%
  • Drug 16%
  • Error 11%
  24 Citations (Scopus)

• Connexin and pannexin signaling in gastrointestinal and liver disease

  Maes, M., Crespo Yanguas, S., Willebrords, J., Cogliati, B. & Vinken, M., 1 Oct 2015, In: Translational Research. 166, 4, p. 332-343

  Research output: Contribution to journal › Article › peer-review

  • Connexins 100%
  • Gastrointestinal Diseases 85%
  • Communication 72%
  • Liver Diseases 67%
  • Gap Junctions 61%
  41 Citations (Scopus)

• Connexin hemichannels: novel mediators of toxicity

  Vinken, M., 1 Jan 2015, In: Archives of Toxicology. 89, 1, p. 143-145 3 p.

  Research output: Contribution to journal › Editorial

  26 Citations (Scopus)

• Derivation and characterization of a cytocompatible scaffold from human testis

  Baert, Y., Stukenborg, J-B., Landreh, M., De Kock, J., Jörnvall, H., Söder, O. & Goossens, E., Jan 2015, In: Human Reproduction. 30, 2, p. 256-267

  Research output: Contribution to journal › Article › peer-review

  • Testis 100%
  • Tissue Scaffolds 48%
  • Organized Financing 44%
  • Sodium Dodecyl Sulfate 40%
  • Mass Spectrometry 33%
  86 Citations (Scopus)

• Development and usability of a computer-tailored pedometer-based physical activity advice for breast cancer survivors

  De Cocker, K., Charlier, C., Van Hoof, E., Pauwels, E., Lechner, L., Bourgois, J., Spittaels, H., Vandelanotte, C. & De Bourdeaudhuij, I., Sept 2015, In: European Journal of Cancer Care. 24, 5, p. 673-682 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cancer Survivors 100%
  • Survivors 80%
  • Exercise 59%
  • Breast Neoplasms 58%
  • Architectural Accessibility 21%
  22 Citations (Scopus)

• Epigenetic modifications as antidedifferentiation strategy for primary hepatocytes in culture.

  Bolleyn, J., Fraczek, J., Rogiers, V. & Vanhaecke, T., 2015, Protocols in In Vitro Hepatocyte Research. Vinken, M. & Rogiers, V. (eds.). New York: Humana Press, p. 203-211 (Methods in Molecular Biology; vol. 1250).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Specialist › peer-review

  • Epigenomics 100%
  • Hepatocytes 96%
  • In Vitro Techniques 33%
  • Extracellular Matrix 32%
  • Phenotype 22%

• Evaluation of a new standardized enzymatic isolation protocol for human umbilical cord-derived stem cells

  Buyl, K., Vanhaecke, T., Desmae, T., Lagneaux, L., Rogiers, V., Najar, M. & De Kock, J., 2015, In: Toxicology in Vitro. 29, 6, p. 1254-1262 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Umbilical Cord 100%
  • Marker 77%
  • Stem Cells 64%
  • Liver 45%
  • Wharton Fragmentation 39%
  16 Citations (Scopus)

• Functionality testing of primary rat hepatocytes by the measurement of urea synthesis

  Bolleyn, J., Rogiers, V. & Vanhaecke, T., 2015, Protocols in in vitro hepatocyte research. New York: Humana Press, p. 317-322

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Specialist › peer-review

  • hepatocytes 100%
  • urea 87%
  • synthesis 61%
  • rats 58%
  • testing 43%

• HS-GC-MS method for the analysis of fragrance allergens in complex cosmetic matrices

  Desmedt, B., Canfyn, M., Pype, M., Baudewyns, S., Hanot, V., Courselle, P., De Beer, J. O., Rogiers, V., De Paepe, K. & Deconinck, E., 2015, In: Talanta. 131, p. 444-451 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Fragrance 100%
  • Allergen 99%
  • Cosmetic 82%
  • Skin Whitening 23%
  • Safety 11%
  45 Citations (Scopus)

• Identification of potential biomarkers of hepatitis B-induced acute liver failure using hepatic cells derived from human skin precursors

  Marcelino Rodrigues, R., Sachinidis, A., De Boe, V., Rogiers, V., Vanhaecke, T. & De Kock, J., 2015, In: Toxicology in Vitro. 29, 6, p. 1231-1239 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Acute Liver Failure 100%
  • Hepatitis B 82%
  • Biological Marker 76%
  • Hepatocytes 71%
  • Biomarkers 55%
  4 Citations (Scopus)

• Immortalized human hepatic cell lines for in vitro testing and research purposes.

  Ramboer, E., Vanhaecke, T., Rogiers, V. & Vinken, M., 2015, Protocols in In Vitro Hepatocyte Research. Vinken, M. & Rogiers, V. (eds.). New York: Humana Press, 24 p. (Methods in Molecular Biology; vol. 1250).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Specialist › peer-review

  • Hepatocytes 100%
  • Cell Line 70%
  • In Vitro Techniques 52%
  • human TERT protein 27%
  • Oncogenes 18%
  45 Citations (Scopus)

• Introduction: connexins, pannexins and their channels as gatekeepers of organ physiology

  Vinken, M., 1 Sept 2015, In: Cellular and Molecular Life Sciences. 72, 15, p. 2775-2778 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Connexins 100%
  39 Citations (Scopus)

• In vitro Dermal Absorption: Sample Application and Seal Quality in a Franz Diffusion Cell System

  Desmedt, B., Courselle, P., De Beer, J. O., Rogiers, V., Deconinck, E. & De Paepe, K., 2015, In: Skin Pharmacology and Physiology. 28, 5, p. 245-249 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Skin Absorption 100%
  • Organisation for Economic Co-Operation and Development 51%
  • In Vitro Techniques 32%
  • Temperature 26%
  • Membranes 22%
  12 Citations (Scopus)

• Measurement of albumin secretion as functionality test in primary hepatocyte cultures

  Buyl, K., De Kock, J., Bolleyn, J., Rogiers, V. & Vanhaecke, T., 2015, Protocols in In Vitro Hepatocyte Research. Vinken, M. & Rogiers, V. (eds.). Springer, p. 303-308 6 p. (Methods in Molecular Biology; vol. 1250).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review

  • Hepatocytes 100%
  • Liver 71%
  • Rats 46%
  • Assays 23%
  • Pathology 22%
  13 Citations (Scopus)

• Metabolomics analysis of the toxicity pathways of triphenyl phosphate in HepaRG cells and comparison to oxidative stress mechanisms caused by acetaminophen

  Van den Eede, N., Cuykx, M., Marcelino Rodrigues, R., Laukens, K., Neels, H., Covaci, A. & Vanhaecke, T., Dec 2015, In: Toxicology in Vitro. 29, 8, p. 2045-2054 10 p.

  Research output: Contribution to journal › Article › peer-review

  • triphenyl phosphate 100%
  • Triphenyl Phosphate 82%
  • Metabolomics 59%
  • Acetaminophen 56%
  • Oxidative Stress 53%
  29 Citations (Scopus)

• MicroRNAs as key regulators of xenobiotic biotransformation and drug response

  Bolleyn, J., De Kock, J., Marcelino Rodrigues, R., Vinken, M., Rogiers, V. & Vanhaecke, T., 2015, In: Archives of Toxicology. 89, 9, p. 1523-1541 19 p.

  Research output: Contribution to journal › Article › peer-review

  • MicroRNA 100%
  • Biotransformation 96%
  • Xenobiotic Agent 94%
  • Xenobiotics 89%
  • MicroRNAs 68%
  15 Citations (Scopus)

• ORAL PRES.: Antioxidant capacity and total phenolic content of Tunisian medicinal plant extracts

  Hamdi, A., Majouli, K., Marzouk, B., Demeyer, K., Marzouk, Z. & Vander Heyden, Y., 2015, Le dixième Congrès international "Qualité des Produits et de l'Environnement: Traitement et Valorisation des Rejets et Effets sur la Santé Humaine QPE-TVR 2015", 10-12 April 2015, Mahdia, Tunisia.

  Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)

• ORAL PRES.: Characterizations of Ipomoea reptans extracts through HPLC and HPTLC fingerprint development, phytochemical profiling, and in-vitro cytotoxicity and antioxidant activity determination

  Hefny Gad Hussein, M., Elsawi, N., Elmewafy, E., Younes, S., Vander Heyden, Y., Demeyer, K. & Mangelings, D., 2015, Chromatographic methods of investigating the organic compounds.

  Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)

  • Thin Layer Chromatography 100%
  • Antioxidant Agent 82%
  • High-Pressure Liquid Chromatography 82%
  • Ethyl 77%
  • Methanol 65%

• ORAL PRES.: Herbal chromatographic fingerprints in the search for new drugs: case study of Pistacia atlantica

  Ben Ahmed, Z., Yousfi, M., Viaene, J., Dejaegher, B., Demeyer, K., Mangelings, D. & Vander Heyden, Y., 2015, XV Chemometrics in Analytical Chemistry, June 22-26th 2015, Changsha, China.

  Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)

  • Antioxidant Agent 100%
  • Drug 69%
  • Energy Parameter 46%
  • Ferricyanide 42%
  • Digallic Acid 38%