Translational Oncology Research Center

Projects

Projects per year 1997 2010 2023 2024 2029

• 28 Active
• 50 Finished

Projects per year

Search results

• Active

  IOF3036: INTEGRAL - Integrating a multimodal approach to address current challenges in immunotherapy

  Van Ginderachter, J., Laoui, D., Movahedi, K., Hadadi, E., Stijlemans, B., Raes, G., Devoogdt, N., Lahoutte, T., De Groof, T., Goyvaerts, C., D'Huyvetter, M., Debacker, J., Breckpot, K., Franceschini, L., Raes, G. & Revets, H.

  1/01/25 → 31/12/29

  Project: Applied

• FWOAL1172: Adenosquamous cancer of the pancreas: decoding the epitome of tumor cell plasticity and defining unique therapeutic angles

  Rooman, I. & Rodriguez Aznar, E.

  1/01/25 → 31/12/27

  Project: Fundamental

• FWOEUAR2: ERA4HEALTH - NANOTECHMEC call: project CHIMERNA

  Breckpot, K.

  1/01/25 → 31/12/27

  Project: Applied

• OZR4385: ULB-VUB Joint Research Group BPCT

  Rooman, I.

  18/12/24 → 18/12/28

  Project: Fundamental

• ANI396: Unravelling mechanisms of cellular plasticity in pancreatic basal cells in homeostasis and disease

  Rooman, I. & Van Lint, S.

  1/11/24 → 31/10/25

  Project: Fundamental

• OZR4356: OZR opvangmandaat aspirant Giada Bertazzon

  Breckpot, K. & Bertazzon, G.

  1/11/24 → 31/10/25

  Project: Fundamental

• FWOTM1257: CATCH - CAR-T cell immunotherapy against Chronic liver disease and Hepatocellular carcinoma

  De Wolf, R., van Grunsven, L. & Breckpot, K.

  1/11/24 → 31/10/28

  Project: Fundamental

• ANI397: Colorectal cancer mRNA therapy focusing on the immune checkpoint ST2

  Breckpot, K. & Marco Aragon, M.

  1/11/24 → 31/10/25

  Project: Fundamental

• FWOTM1240: Advancing Pancreatic Cancer Treatment through Subtype-Specific Strategies Using Artificial Intelligence

  Messaoudi, N.

  1/10/24 → 30/09/29

  Project: Fundamental

• AIIFUND125: APAF/IAP 2024 Young Investigator in Pancreatology Grant

  Rooman, I. & Baldan, J.

  1/10/24 → 30/09/25

  Project: Fundamental

• HERC66: 3D-CELLMAP: Unveiling complex cellular interactions in tissues through 3D super-resolution protein multiplex imaging

  Movahedi, K., Rooman, I., Sermon, K., De Bundel, D., Fioravanti, A., Staels, W., Magez, S., Breckpot, K., De Kock, J., Laoui, D., Goyvaerts, C., Smolders, I., Van Ginderachter, J., Marcelino Rodrigues, R., De Leu, N., van Grunsven, L., Hernot, S., Peeters, E., Vanhaecke, T., De Veirman, K., Ruytinx, J., Van Schependom, J., Kortekaas, I. & Goossens, E.

  1/05/24 → 31/05/28

  Project: Fundamental

  • Tissue 100%
  • Imaging techniques 89%
  • Proteins 86%
  • Microscopic examination 50%
  • Multiplexing 48%

• OZR4286: Financiering MZW OZR: DELI-SORT: MACSQuant® Tyto for sterile DELicate Immune cells SORTing

  Laoui, D., Vanginderachter, J. A., Magez, S., Tuyaerts, S., Fioravanti, A., Devoogdt, N., Van der Henst, C., Raes, G., Stijlemans, B., Hadadi, E., De Trez, C., Ruytinx, J., Brunner, J., De Groof, T. & De Veirman, K.

  24/04/24 → 24/04/28

  Project: Fundamental

  • cells 100%
  • Tyto 97%
  • sorting 57%
  • droplets 53%
  • therapeutics 44%

• OZR4292: Financiering MZW OZR: Biolayer interferometry to study protein-protein and protein-ligand interactions

  Versées, W., Loris, R., Rooman, I., Laoui, D., Messens, J., Brunner, J., Stijlemans, B. & Ballet, S.

  24/04/24 → 24/04/28

  Project: Fundamental

  • Interferometry 100%
  • Ligands 38%
  • Proteins 30%
  • Temperature 9%
  • Thermodynamics 8%

• OZR4288: Financiering MZW OZR: RAPTOR: Rapid Analysis and production of Proteins for clinical Translation using biacORe and bioreactOR systems.

  Devoogdt, N., Hernot, S., De Groof, T., Ballet, S., Stijlemans, B., Massie, A., Rooman, I., Keyaerts, M., Raes, G., De Kock, J., Breckpot, K., De Veirman, K. & Caveliers, V.

  24/04/24 → 24/04/28

  Project: Fundamental

  • bioreactors 100%
  • translation (genetics) 88%
  • Bioreactors 49%
  • Proteins 37%
  • proteins 34%

• OZR4289: Financiering MZW OZR: E.S.P.R.I.T.: Epigenomics, Sleep and Pain center for Research, Intervention and Translational science

  Mairesse, O., Nijs, J. & De Bruyne, E.

  24/04/24 → 24/04/28

  Project: Fundamental

  • Pain Clinics 100%
  • Translational Medical Research 87%
  • Sleep 80%
  • Epigenomics 67%
  • Sleep Deprivation 30%

• BASGO38: OZR Basisfinanciering voor Grote Onderzoeksgroepen - TORC

  Vanderkerken, K.

  1/01/24 → 31/12/29

  Project: Fundamental

• ANI374: Targeting pro-tumoral exosomal exchanges with CD138-syntenin inhibitors : a novel therapeutic approach for Multiple Myeloma

  Menu, E.

  1/01/24 → 31/12/27

  Project: Fundamental

  • Syntenins 100%
  • Multiple Myeloma 69%
  • Exosomes 24%
  • Bone Marrow 12%
  • Syndecans 9%

• FWOSB161: FORX - FOod interventions to Reduce immunotherapy toXicity

  Verhaert, M. & Aspeslagh, S.

  1/11/23 → 31/10/27

  Project: Fundamental

  • food 100%

• FWOTBM13: TBM Project: Ultra-sensitive minimal residual disease assessment by blood-based clonotypic mass spectrometry approach in plasma cell dyscrasias (MASSIAS)

  Van Riet, I. & Bakkus, M.

  1/10/23 → 30/09/27

  Project: Applied

  • Mass Spectrometry 100%
  • Residual Neoplasm 70%
  • Peptides 49%
  • Paraproteinemias 41%
  • Bone Marrow 24%

• ANI353: Harnessing the proliferative regulation of the cancer cell of origin to halt pancreatic cancer

  Rooman, I. & Baldan, J.

  1/10/23 → 30/09/27

  Project: Fundamental

  • Pancreatic Neoplasms 100%
  • Exocrine Pancreas 23%
  • Neoplasms 22%
  • Second Primary Neoplasms 20%
  • Disease Progression 14%

• ANI352: MOTUNE-T therapy: Metabolically Optimized TUNEd T cells as treatment for recurrent glioblastoma

  Neyns, B. & Geeraerts, X.

  1/10/23 → 1/06/28

  Project: Fundamental

  • Glioblastoma 100%
  • T-Lymphocytes 48%
  • Ipilimumab 31%
  • Nivolumab 30%
  • Therapeutics 22%

• EUAR135: BAXERNA 2.0 : Immunopeptidomics-based Development of Next-Generation Bacterial mRNA Vaccines

  Breckpot, K.

  1/07/23 → 30/06/28

  Project: Applied

  • Bacterial Vaccines 100%
  • Messenger RNA 96%
  • Alpha-Galactosylceramide 86%
  • alpha-galactosylceramide 77%
  • Vaccines 71%

• OZR4090: BAXERNA 2.0 (EU BONUS OZR)

  Breckpot, K.

  1/03/23 → 28/02/27

  Project: Fundamental

  • Alpha-Galactosylceramide 100%
  • alpha-galactosylceramide 88%
  • Cancer Vaccines 71%
  • Nanoparticles 52%
  • Lipid 40%

• ANI342: InterCePPT: Interfere with Cellular Positioning in the Pancreatic Tumor

  Rooman, I.

  1/01/23 → 31/12/26

  Project: Fundamental

  • Neoplasms 100%
  • Stromal Cells 34%
  • Pancreatic Neoplasms 32%
  • Bioprinting 26%
  • Peptidomimetics 25%

• ANI322: NANO-AXL: Nanobody-based imaging and targeting of AXL positive tumor cells in Acute Myeloid Leukemia and Multiple Myeloma

  De Veirman, K.

  1/01/23 → 31/12/26

  Project: Fundamental

  • Single-Domain Antibodies 100%
  • Multiple Myeloma 62%
  • Acute Myeloid Leukemia 60%
  • Neoplasms 27%
  • Recurrence 7%

• EUPOM129: Erasmus Standard Budget-based + LS Type II : European Universities Transforming to an Open Inclusive Academy - Making Organisational and Real Evolution (EUTOPIA – MORE)

  Vanderkerken, K., De Potter, L. & Bellotti, M.

  1/12/22 → 30/11/26

  Project: Applied

  • academy 100%
  • budget 89%
  • staff 45%
  • university 34%
  • stakeholder 26%

• OZR3983: Bilateral cooperation within the framework of a joint doctoral project: benchfee for joint PhD VUB - KU Leuven, TU Chenggong

  Menu, E.

  7/07/22 → 6/07/26

  Project: Fundamental

• OZR2835: Onderzoeksgroep Alliantie VUB - UGent - Research Consortium on particle based immunotherapy

  Breckpot, K. & De Smedt, S.

  10/07/15 → 10/07/27

  Project: Policy Based

  • Immunotherapy 100%