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Expertise
I study the effects of cholestasis on connexin hemichannels and pannexin channels. This VUB-KUL joint project intends to investigate the potential of connexin43 and pannexin1 (hemi)channels as drug targets and biomarkers in cholestasis by relying on in vitro and in vivo models as well as on the testing of human cholestatic liver samples.
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Projects
- 1 Active
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FWOSB75: Connexin hemichannels and pannexin channels as mediators and in vitro indicators of drug-induced cholestatic liver injury.
1/11/19 → 31/10/21
Project: Fundamental
Research output
- 20 Citations
- 3 h-Index
- 7 Article
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Cholestasis differentially affects liver connexins.
Cooreman, A., Van Campenhout, R., Crespo Yanguas, S., Gijbels, E., Leroy, K., Pieters, A., Tabernilla Garcia, A., Van Brantegem, P., Annaert, P., Cogliati, B. & Vinken, M., 7 Sep 2020, In : International Journal of Molecular Sciences. 21, 18, 18 p., 6534.Research output: Contribution to journal › Article
Open AccessFile10 Downloads (Pure) -
Non-canonical roles of connexins.
Van Campenhout, R., Cooreman, A., Leroy, K., Rusiecka, O. M., Van Brantegem, P., Annaert, P., Muyldermans, S., Devoogdt, N., Cogliati, B., Kwak, B. R. & Vinken, M., Jul 2020, In : Progress in Biophysics and Molecular Biology. 153, p. 35-41 7 p.Research output: Contribution to journal › Article
5 Citations (Scopus) -
Targeting gap junctional intercellular communication by hepatocarcinogenic compounds
Leroy, K., Pieters, A., Tabernilla Garcia, A., Cooreman, A., Van Campenhout, R., Cogliati, B. & Vinken, M., 17 Aug 2020, In : Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 23, 6, p. 255-275 21 p.Research output: Contribution to journal › Article
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Connexin and pannexin (hemi)channels: emerging targets in the treatment of liver disease. IF 14.679
Cooreman, A., Van Campenhout, R., Ballet, S., Annaert, P., Van Den Bossche, B., Colle, I., Cogliati, B. & Vinken, M., 1 Mar 2019, In : Hepatology. 69, 3, p. 1317-1323 7 p.Research output: Contribution to journal › Article
6 Citations (Scopus) -
Increased expression of adherens junction components in mouse liver following bile duct ligation
Van Campenhout, R., Crespo Yanguas, S., Cooreman, A., Gijbels, E., Leroy, K., Vilas-Boas, V., Devoogdt, N., Muyldermans, S., Cogliati, B. & Vinken, M., 22 Oct 2019, In : Biomolecules. 9, 10, 636.Research output: Contribution to journal › Article
Open Access1 Citation (Scopus)
Activities
- 1 Participation in workshop, seminar
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BelTox/IC-3Rs/INVITROM joint symposium
Vera Rogiers (Chair), Mathieu Vinken (Chair), Emma Gustafson (Organiser), Eva Gijbels (Organiser), Axelle Cooreman (Organiser), Raf Van Campenhout (Organiser), Quinten Marcelis (Organiser), Matthias Rombaut (Organiser), Joost Boeckmans (Organiser), Mieke Van Mulders (Organiser), Nancy Marie Antonia Liodo Missigba (Organiser), Ruani Fernando (Organiser)21 Nov 2019 → 22 Nov 2019Activity: Participating in or organising an event › Participation in workshop, seminar
Thesis
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Assessment of connexin and pannexin expression in drug-induced cholestasis using an in vitro model.
Author: Bossuyt, C. J., Cooreman, A. & Vinken, M., 2020Supervisor: Cooreman, A. (Advisor) & Vinken, M. (Promotor)
Student thesis: Master's Thesis
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Characterization of connexin and pannexin expression in an in vivo and in vitro model of cholestasis
Author: Moudallel, R., Cooreman, A. & Vinken, M., 2019Supervisor: Cooreman, A. (Advisor) & Vinken, M. (Promotor)
Student thesis: Master's Thesis