Projects per year
Personal profile
Expertise
I study the effects of cholestasis on connexin hemichannels and pannexin channels. This VUB-KUL joint project intends to investigate the potential of connexin43 and pannexin1 (hemi)channels as drug targets and biomarkers in cholestasis by relying on in vitro and in vivo models as well as on the testing of human cholestatic liver samples.
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Dive into the research topics where Axelle Cooreman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Projects
- 1 Finished
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FWOSB75: Connexin hemichannels and pannexin channels as mediators and in vitro indicators of drug-induced cholestatic liver injury.
1/11/19 → 31/10/23
Project: Fundamental
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Assessment of connexin43 hemichannel functionality based on cytosolic uptake of Yo-Pro1
Van Campenhout, R., Sanz-Serrano, J., Cooreman, A., De Vlaeminck, Y., Breckpot, K., Kadam, P., Tabernilla Garcia, A. & Vinken, M., 6 Apr 2024, In: Methods in Molecular Biology. 2801, p. 75-85 11 p., 6.Research output: Contribution to journal › Article
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Assessment of connexin43 hemichannel functionality based on cytosolic uptake of Yo-Pro1
Van Campenhout, R., Sanz-Serrano, J., Cooreman, A., De Vlaeminck, Y., Breckpot, K., Kadam, P., Tabernilla Garcia, A. & Vinken, M., 2024, Assessment of connexin43 hemichannel functionality based on cytosolic uptake of Yo-Pro1. Mammano, F. & Retamal, M. (eds.). Methods in Molecular Biology, Vol. 2801. p. 75-85Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Effects of bile duct ligation on cell junctions in mouse liver
Van Campenhout, R., Cooreman, A., Cogliati, B. & Vinken, M., 21 Sep 2023.Research output: Unpublished contribution to conference › Poster
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Optimization of an adverse outcome pathway network on chemical-induced cholestasis using an artificial intelligence-assisted data collection and confidence level quantification approach
van Ertvelde, J., Verhoeven, A., Maerten, A., Cooreman, A., dos Santos Rodrigues, B., Sanz-Serrano, J., Mihajlovic, M., Tripodi, I., Teunis, M., Jover, R., Luechtefeld, T., Vanhaecke, T., Jiang, J. & Vinken, M., 1 Sep 2023, In: Journal of biomedical informatics. 145, 1 p., 104465.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)29 Downloads (Pure) -
Role of connexins and their channels in cholestasis
Cooreman, A., 2023, 215 p.Research output: Thesis › PhD Thesis
Prizes
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Best oral presentation award
Cooreman, Axelle (Recipient), Caufriez, A. (Recipient), Tabernilla Garcia, Andres (Recipient), Van Campenhout, Raf (Recipient), Leroy, K. (Recipient), Sanz Serrano, Julen (Recipient), Kadam, Prashant (Recipient), dos Santos Rodrigues, B. (Recipient), Lamouroux, A. (Recipient), Ballet, Steven (Recipient), Annaert, P. (Recipient) & Vinken, Mathieu (Recipient), 24 Nov 2022
Prize: Prize (including medals and awards)
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Best Poster Presentation Award
Leroy, K. (Recipient), Cooreman, Axelle (Recipient), Van Campenhout, Raf (Recipient), Cogliati, B. (Recipient) & Vinken, Mathieu (Recipient), 24 Nov 2022
Prize: Prize (including medals and awards)
Activities
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Effects of bile duct ligation on cell junctions in mouse liver
Raf Van Campenhout (Speaker), Axelle Cooreman (Contributor), Bruno Cogliati (Contributor) & Mathieu Vinken (Contributor)
22 Sep 2023Activity: Talk or presentation › Talk or presentation at a conference
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Effects of cholestatic drugs on connexins,their channels and bile acid transporters
Axelle Cooreman (Speaker)
18 Mar 2022Activity: Talk or presentation › Talk at an external academic organisation
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Effects of drugs formerly repurposed for COVID-19 treatment on connexin43 hemichannels and pannexin1 channels
Axelle Cooreman (Speaker), Anne Caufriez (Contributor), Andres Tabernilla Garcia (Contributor), Raf Van Campenhout (Contributor), Kaat Leroy (Contributor), Julen Sanz Serrano (Contributor), Prashant Kadam (Contributor), Bruna dos Santos Rodrigues (Contributor), Arthur Lamouroux (Contributor), Steven Ballet (Contributor), Pieter Annaert (Speaker) & Mathieu Vinken (Contributor)
24 Nov 2022Activity: Talk or presentation › Talk or presentation at a conference
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Effects of COVID-19 drugs on connexin43
Axelle Cooreman (Speaker)
22 Nov 2021Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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IC-3Rs Symposium 2021 ''Human-relevant models for drug research and development''
Vera Rogiers (Chair), Bernward Garthoff (Member of programme committee), Axelle Cooreman (Organiser), Quinten Marcelis (Organiser), Alexandra Gatzios (Organiser), Emma Arnesdotter (Organiser), Sara Sepehri (Organiser), Mieke Van Mulders (Organiser), Fabienne Van Bamis (Organiser), Anouck Thienpont (Organiser) & Mona Delagrange (Organiser)
7 Oct 2021 → 8 Oct 2021Activity: Participating in or organising an event › Participation in conference
Thesis
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Effect of COVID-19 drugs on connexin43
Author: Willems, O., Cooreman, A. & Vinken, M., 2021Student thesis: Master's Thesis
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Effects of COVID-19 drugs and peptidomimetic-based inhibitors on connexins and their channels
Author: Nogueira Da Silva Gonçalves, M. D. M., Cooreman, A., Caufriez, A. & Vinken, M., 2022Student thesis: Master's Thesis