Projects per year
Personal profile
Expertise
I study the effects of cholestasis on connexin hemichannels and pannexin channels. This VUB-KUL joint project intends to investigate the potential of connexin43 and pannexin1 (hemi)channels as drug targets and biomarkers in cholestasis by relying on in vitro and in vivo models as well as on the testing of human cholestatic liver samples.
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Projects
- 1 Active
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FWOSB75: Connexin hemichannels and pannexin channels as mediators and in vitro indicators of drug-induced cholestatic liver injury.
1/11/19 → 31/10/21
Project: Fundamental
Research output
- 36 Citations
- 4 h-Index
- 9 Article
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Bosentan alters endo- and exogenous bile salt disposition in sandwich-cultured human hepatocytes
Oorts, M., Van Brantegem, P., Deferm, N., Chatterjee, S., Dreesen, E., Cooreman, A., Vinken, M., Richert, L. & Annaert, P., 31 Oct 2021, In : Journal of Pharmacology and Experimental Therapeutics. 379, 1, p. 20-32 13 p.Research output: Contribution to journal › Article
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In Vitro Liver Toxicity Testing of Chemicals: A Pragmatic Approach
Tabernilla Garcia, A., dos Santos Rodrigues, B., Pieters, A., Caufriez, A., Leroy, K., Van Campenhout, R., Cooreman, A., Coelho Gomes, A. R., Arnesdotter, E., Gijbels, E. & Vinken, M., 1 May 2021, In : International Journal of Molecular Sciences. 22, 9, p. 1-45 45 p., 5038.Research output: Contribution to journal › Article
Open AccessFile1 Citation (Scopus)3 Downloads (Pure) -
Cholestasis differentially affects liver connexins.
Cooreman, A., Van Campenhout, R., Crespo Yanguas, S., Gijbels, E., Leroy, K., Pieters, A., Tabernilla Garcia, A., Van Brantegem, P., Annaert, P., Cogliati, B. & Vinken, M., 2 Sep 2020, In : International Journal of Molecular Sciences. 21, 18, p. 1-18 18 p., 6534.Research output: Contribution to journal › Article
Open AccessFile1 Citation (Scopus)38 Downloads (Pure) -
Non-canonical roles of connexins.
Van Campenhout, R., Cooreman, A., Leroy, K., Rusiecka, O. M., Van Brantegem, P., Annaert, P., Muyldermans, S., Devoogdt, N., Cogliati, B., Kwak, B. R. & Vinken, M., Jul 2020, In : Progress in Biophysics and Molecular Biology. 153, p. 35-41 7 p.Research output: Contribution to journal › Article
Open AccessFile6 Citations (Scopus) -
Targeting gap junctional intercellular communication by hepatocarcinogenic compounds
Leroy, K., Pieters, A., Tabernilla Garcia, A., Cooreman, A., Van Campenhout, R., Cogliati, B. & Vinken, M., 17 Aug 2020, In : Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 23, 6, p. 255-275 21 p.Research output: Contribution to journal › Article
Open AccessFile1 Citation (Scopus)4 Downloads (Pure)
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LSM PHD DAY
Margo Willems (Chair), Wout De Mey (Chair), Axelle Cooreman (Organiser), Michiel De Coster (Organiser), Hamide Yildirim (Organiser), Catharina Muylaert (Organiser)31 Mar 2021Activity: Participating in or organising an event › Participation in workshop, seminar
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Connexin expression in cholestatic liver injury
Axelle Cooreman (Speaker)7 Sep 2020Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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PANACHE Science Xpression online workshop
Axelle Cooreman (Participant)6 Sep 2020 → 7 Sep 2020Activity: Participating in or organising an event › Participation in workshop, seminar
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BelTox/IC-3Rs/INVITROM joint symposium
Vera Rogiers (Chair), Mathieu Vinken (Chair), Emma Gustafson (Organiser), Eva Gijbels (Organiser), Axelle Cooreman (Organiser), Raf Van Campenhout (Organiser), Quinten Marcelis (Organiser), Matthias Rombaut (Organiser), Joost Boeckmans (Organiser), Mieke Van Mulders (Organiser), Nancy Marie Antonia Liodo Missigba (Organiser), Ruani Fernando (Organiser)21 Nov 2019 → 22 Nov 2019Activity: Participating in or organising an event › Participation in workshop, seminar
Thesis
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Assessment of connexin and pannexin expression in drug-induced cholestasis using an in vitro model.
Author: Bossuyt, C. J., Cooreman, A. & Vinken, M., 2020Supervisor: Cooreman, A. (Advisor) & Vinken, M. (Promotor)
Student thesis: Master's Thesis
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Characterization of connexin and pannexin expression in an in vivo and in vitro model of cholestasis
Author: Moudallel, R., Cooreman, A. & Vinken, M., 2019Supervisor: Cooreman, A. (Advisor) & Vinken, M. (Promotor)
Student thesis: Master's Thesis
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Effect of COVID-19 drugs on connexin43
Author: Willems, O., Cooreman, A. & Vinken, M., 2021Student thesis: Master's Thesis