Projects per year
Personal profile
Expertise
I study the effects of cholestasis on connexin hemichannels and pannexin channels. This VUB-KUL joint project intends to investigate the potential of connexin43 and pannexin1 (hemi)channels as drug targets and biomarkers in cholestasis by relying on in vitro and in vivo models as well as on the testing of human cholestatic liver samples.
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Dive into the research topics where Axelle Cooreman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
- 1 Finished
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FWOSB75: Connexin hemichannels and pannexin channels as mediators and in vitro indicators of drug-induced cholestatic liver injury.
1/11/19 → 31/10/21
Project: Fundamental
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Connexin-based channels in the liver.
Van Campenhout, R., Leroy, K., Cooreman, A., Tabernilla Garcia, A., Cogliati, B., Kadam, P. & Vinken, M., 12 Aug 2022, In: Comprehensive Physiology. 12, 4, p. 1-17 17 p.Research output: Contribution to journal › Article › peer-review
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Effects of drugs formerly proposed for COVID-19 treatment on connexin43 hemichannels.
Cooreman, A., Caufriez, A., Tabernilla Garcia, A., Van Campenhout, R., Leroy, K., Kadam, P., Sanz-Serrano, J., dos Santos Rodrigues, B., Annaert, P. & Vinken, M., 1 May 2022, In: International Journal of Molecular Sciences. 23, 9, 16 p., 5018.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)21 Downloads (Pure) -
Effects of drugs formerly suggested for COVID-19 repurposing on pannexin1 channels.
Caufriez, A., Tabernilla Garcia, A., Van Campenhout, R., Cooreman, A., Leroy, K., Sanz-Serrano, J., Kadam, P., dos Santos Rodrigues, B., Lamouroux, A., Ballet, S. & Vinken, M., 19 May 2022, In: International Journal of Molecular Sciences. 23, 10, 21 p., 5664.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Downloads (Pure) -
Update and optimization of an adverse outcome pathway network of chemical-induced cholestasis
van Ertvelde, J., Verhoeven, A., Maerten, A., Cooreman, A., dos Santos Rodrigues, B., Sanz-Serrano, J., Mihajlovic, M., Jover, R., Vanhaecke, T., Jiang, J. & Vinken, M., 2022, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Bosentan alters endo- and exogenous bile salt disposition in sandwich-cultured human hepatocytes
Oorts, M., Van Brantegem, P., Deferm, N., Chatterjee, S., Dreesen, E., Cooreman, A., Vinken, M., Richert, L. & Annaert, P., 1 Oct 2021, In: Journal of Pharmacology and Experimental Therapeutics. 379, 1, p. 20-32 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)10 Downloads (Pure)
Activities
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Effects of cholestatic drugs on connexins,their channels and bile acid transporters
Axelle Cooreman (Speaker)
18 Mar 2022Activity: Talk or presentation › Talk at an external academic organisation
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LSM PHD DAY
Margo Willems (Chair), Wout De Mey (Chair), Axelle Cooreman (Organiser), Michiel De Coster (Organiser), Hamide Yildirim (Organiser) & Catharina Muylaert (Organiser)
31 Mar 2021Activity: Participating in or organising an event › Participation in workshop, seminar
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Effects of COVID-19 drugs on connexin43
Axelle Cooreman (Speaker)
22 Nov 2021Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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IC-3Rs Symposium 2021 ''Human-relevant models for drug research and development''
Vera Rogiers (Chair), Bernward Garthoff (Member of programme committee), Axelle Cooreman (Organiser), Quinten Marcelis (Organiser), Alexandra Gatzios (Organiser), Emma Arnesdotter (Organiser), Sara Sepehri (Organiser), Mieke Van Mulders (Organiser), Fabienne Van Bamis (Organiser), Anouck Thienpont (Organiser) & Mona Delagrange (Organiser)
7 Oct 2021 → 8 Oct 2021Activity: Participating in or organising an event › Participation in conference
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PANACHE workshop
Axelle Cooreman (Participant)
22 Nov 2021Activity: Participating in or organising an event › Participation in workshop, seminar
Thesis
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Effect of COVID-19 drugs on connexin43
Author: Willems, O., Cooreman, A. & Vinken, M., 2021Student thesis: Master's Thesis
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Effects of COVID-19 drugs and peptidomimetic-based inhibitors on connexins and their channels
Author: Nogueira Da Silva Gonçalves, M. D. M., Cooreman, A., Caufriez, A. & Vinken, M., 2022Student thesis: Master's Thesis