Projects per year
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Finished
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FWOTM1019: DNA methyltransferase 3B (DNMT3B) in multiple myeloma: a pivotal role in myeloma cell survival, drug resistance and disease progression?
Muylaert, C. (Mandate) & De Bruyne, E. (Administrative Promotor)
1/11/20 → 31/10/24
Project: Fundamental
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DNA methyltransferase 3B in multiple myeloma: A pivotal role in myeloma cell survival, drug resistance and disease progression
Muylaert, C., 2025, 213 p.Research output: Thesis › PhD Thesis
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Dual targeting of G9a and DNMTs induces antitumor effects in multiple myeloma
Nylund, P., Garrido-Zabala, B., Tziola, S. I., Mohajershojai, T., Berglund, H., Muylaert, C., Van Hemelrijck, L. A., Atienza Párraga, A., Vasquez, L., Jacob, J., Bergquist, E., Martín-Subero, J. I., Öberg, F., Karlsson, T., Nestor, M., De Bruyne, E., Kalushkova, A. & Wiklund, H. J., 14 Oct 2025, In: Blood Advances. 9, 19, p. 4825-4841 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting MAT2A alters the methylation landscape and DNA damage response in Multiple Myeloma, revealing novel combination strategies.
Van Hemelrijck, L. A., Wang, Y., Muylaert, C., Olsen, C., De Veirman, K., Vanderkerken, K., Menu, E. & De Bruyne, E., 7 Feb 2025. 1 p.Research output: Unpublished contribution to conference › Poster
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Targeting Transcription-Replication Conflicts using G-quadruplexes stabilizers in Multiple Myeloma.
Dutrieux, L., Ovejero, S., Guillemin, A., Zellagui, L., De Bruyne, E., Muylaert, C., Van Hemelrijck, L. A., Lin, Y.-L., Loughran, E., Choquet, A., Magat, T., Bouchouika, S., Bret, C., Requirand, G., Robert, N., Vincent, L., Carton, G., Herbaux, C., Rodriguez, R. & Cogne, M. & 5 others, , May 2025, In: Blood Neoplasia. 2, 2, p. 1-16 16 p., 100072.Research output: Contribution to journal › Article › peer-review
Open Access -
The de novo DNA methyltransferase 3B is a novel epigenetic regulator of MYC in multiple myeloma, representing a promising therapeutic target to counter relapse
Muylaert, C., Van Hemelrijck, L. A., Van der Vreken, A., Heestermans, R., Satilmis, H., Verheye, E., Alaterre, E., Olsen, C., De Beule, N., De Veirman, K., Menu, E., Vanderkerken, K., Moreaux , J. & De Bruyne, E., 17 Apr 2025, In: Journal of Experimental & Clinical Cancer Research. 44, 1, 18 p., 125.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus)
Prizes
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Best Poster Presentation BHS 2025
Van Hemelrijck, L. A. (Recipient), Wang, Y. (Recipient), Muylaert, C. (Recipient), Olsen, C. (Recipient), De Veirman, K. (Recipient), Vanderkerken, K. (Recipient), Menu, E. (Recipient) & De Bruyne, E. (Recipient), 7 Feb 2025
Prize: Prize (including medals and awards)
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BHS training grant
Muylaert, C. (Recipient) & De Bruyne, E. (Recipient), Dec 2022
Prize: Other distinction
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Targeting DNMT3B impairs multiple myeloma cell proliferation and clonogenic capacity and enhances sensitivity to standard of care agents.
Muylaert, C. (Recipient), Menu, E. (Recipient) & De Bruyne, E. (Recipient), Sept 2023
Prize: Prize (including medals and awards)
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Targeting of DNMT3B in the plasma cell cancer multiple myeloma disturbs cancer cell growth and clonogenicity and boosts the anti-tumor activity of the proteasome inhibitor bortezomib
Muylaert, C. (Recipient), Menu, E. (Recipient) & De Bruyne, E. (Recipient), 30 Sept 2022
Prize: Prize (including medals and awards)
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The de novo DNA methyltransferase DNMT3B: A new promising target in multiple myeloma
Muylaert, C. (Recipient), Menu, E. (Recipient) & De Bruyne, E. (Recipient), 2022
Prize: Prize (including medals and awards)
Activities
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Targeting DNMT3B in multiple myeloma: a novel epigenetic-based targeting approach that displays potent anti-myeloma activity and enhances sensitivity to standard of care agents
Muylaert, C. (Speaker) & De Bruyne, E. (Speaker)
2 Feb 2024Activity: Talk or presentation › Talk or presentation at a conference
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Internship of 1 month in collaborating lab (Laboratory for Monitoring Innovative Therapies Department of Biological Hematology CHRU de Montpellier, Hôpital St Eloi, Montpellier, France)
Muylaert, C. (Visitor)
4 Jan 2023 → 6 Feb 2023Activity: Other › Research and Teaching at External Organisation
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LSM-PhD Day 2023
Vandewalle, N. (Organiser), Hanssens, H. (Organiser), Yildirim, H. (Organiser), Wyns, A. (Organiser), Van Hemelrijck, L. A. (Organiser), Muylaert, C. (Organiser), Janssens, C. (Organiser), De Coster, M. (Organiser), De Pauw, L. (Organiser) & Vanonckelen, O. (Organiser)
28 Mar 2023Activity: Participating in or organising an event › Participation in conference
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Charity Quiz PhD United 2023
Vandewalle, N. (Organiser), Geirnaert, F. (Organiser), Wyns, A. (Organiser), Muylaert, C. (Organiser), Walckiers, J. (Organiser), Lobo, M. (Organiser), Vanonckelen, O. (Organiser), Van Hemelrijck, L. A. (Organiser), Van Campenhout, J. (Organiser), Van der Vliet, M. (Organiser), Hanssens, H. (Organiser), Janssens, C. (Organiser), De Coster, M. (Organiser), Van den Bossche, J.-L. (Organiser) & Coolens, K. (Organiser)
14 Dec 2023Activity: Participating in or organising an event › Participating in or organizing a school event
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LSM-PhD day 2022
Muylaert, C. (Organiser)
29 Mar 2022Activity: Participating in or organising an event › Participating in or organizing a school event