Research output

Research output per year 2007 2009 2012 2013 2016 2017 2018 2019 2020 2021 2023 2024 2025

• 235 Citations
• 8 h-index
• 30 Poster
• 29 Meeting abstract (Journal)
• 20 Article
• 3 Conference paper
• 1 More
  • 1 PhD Thesis

Research output per year

Research output per year

Search results

• 2025

  How we treat severe inherited antithrombin deficiency: lessons from cases homozygous for the Budapest 3 variant

  Bravo-Perez, C., Corral, J., Orlando, C., Ignjatovic, V., Ilonczai, P. & Bereczky, Z., Feb 2025, In: Journal of Thrombosis and Haemostasis. 21 p.

  Research output: Contribution to journal › Article › peer-review
• 2024

  Antithrombin deficiency: report of a rare case homozygous for p.Leu131Phe Heparin Binding Site mutation

  Cherkaoui, S., Orlando, C., Dedeken, L., Demulder, A. & Rozen, L., 2024, In: Belgian Journal of Hematology. 1 p.

  Research output: Contribution to journal › Meeting abstract (Journal)

• Diagnostic performance of commercial antithrombin activity assays: do we get what we expect?

  Orlando, C., Drèze, C., Evenepoel, A., Seneca, S. & Jochmans, K., 2024, In: Belgian Journal of Hematology. 1 p.

  Research output: Contribution to journal › Meeting abstract (Journal)

• Routine hemostasis parameters on the CN6000: analytical validation and method comparison with ACL TOP750

  Evenepoel, A., Drèze, C., Cristelli, E. & Orlando, C., 2024, In: Belgian Journal of Hematology. 1 p.

  Research output: Contribution to journal › Meeting abstract (Journal)

• Routine hemostasis parameters on the CN6000: analytical validation and method comparison with ACL TOP750

  Evenepoel, A., Drèze, C., Cristelli, E. & Orlando, C., 2024, (Unpublished).

  Research output: Unpublished contribution to conference › Poster

• The use of direct oral anticoagulants in the secondary prevention of venous thromboembolism in patients with severe thrombophilia: communication from the ISTH SSC Subcommittee on Physiological Anticoagulants and Thrombophilia

  Kovac, M., Ignjatovic, V., Orlando, C., Bereczky, Z. & Hunt, B. J., Nov 2024, In: Journal of Thrombosis and Haemostasis. 22, 11, p. 3322-3329 8 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)
• 2023

  Genotype-phenotype correlation in Belgian patients with inherited Protein C deficiency

  Bouteille, S. P., Stouffs, K., Jochmans, K. & Orlando, C., 2023, In: Belgian Journal of Hematology. 1, 1 p.

  Research output: Contribution to journal › Meeting abstract (Journal)

• Genotype-phenotype correlation in Belgian patients with inherited Protein C deficiency

  Bouteille, S. P., Stouffs, K., Jochmans, K. & Orlando, C., 24 Jun 2023, (Unpublished).

  Research output: Unpublished contribution to conference › Poster

• Improving Genetic Testing for Antithrombin Deficiency by Optimizing ACMG/AMP Variant Curation Guidelines for the SERPINC1 Gene

  Lee, K., Mohan, S., Tracy, S., Morales-Rosado, J., Branchford, B., Castoldi, E., Li, A., Orlando, C., Payne, A., Trapp-Stamorski, V., Tregouet, D. & Morrange, P., 2023, (Unpublished).

  Research output: Unpublished contribution to conference › Poster

• Prothrombotic polymorphisms FV Leiden and prothrombin G20210A in 699 unrelated patients with congenital antithrombin deficiency: more than a prognostic value

  Bravo-Pérez, C., Orlando, C., Gindele, R., Cifuentes, R., Stouffs, K., Ilonczai, P., de la Morena-Barrio, M. E., Schlammadinger, A., Pflieger, G., Corral, J., Jochmans, K. & Bereczky, Z., 2023, In: Research and Practice in Thrombosis and Haemostasis. 7, 2, 1 p.

  Research output: Contribution to journal › Meeting abstract (Journal)

• The 2023 Belgian clinical guidance on anticoagulation management in hospitalized and ambulatory COVID-19 patients

  Vanassche, T., Engelen, M. M., Orlando, C., Vandenbosch, K., Gadisseur, A., Hermans, C., Jochmans, K., Minon, J-M., Motte, S., Peperstraete, H., Péters, P., Sprynger, M., Lancellotti, P., Dehaene, I., Emonts, P., Vandenbriele, C., Verhamme, P. & Oury, C., Dec 2023, In: Acta Clinica Belgica. 78, 6, p. 497-508 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Hemorrhage 100%
• 2022

  Belgian clinical guidance on anticoagulation management in hospitalised and ambulatory patients with COVID-19

  Vanassche, T., Orlando, C., Vandenbosch, K., Gadisseur, A., Hermans, C., Jochmans, K., Minon, J-M., Motte, S., Peperstraete, H., Péters, P., Sprynger, M., Lancellotti, P., Dehaene, I., Emonts, P., Vandenbriele, C., Verhamme, P. & Oury, C., Apr 2022, In: Acta Clinica Belgica. 77, 2, p. 280-285 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Venous Thromboembolism 100%
  • Primary Care Physicians 98%
  • Occupational Groups 66%
  • Clinical Trials 60%
  • Delivery of Health Care 56%
  12 Citations (Scopus)

• Dialyzer Performance During Hemodialysis Without Systemic Anticoagulation Using a Heparin-Grafted Dialyzer Combined With a Citrate-Enriched Dialysate: Results of the Randomized Crossover Noninferiority EVOCIT Study

  François, K., De Clerck, D., Tonnelier, A., Cambier, M-L., Orlando, C., Jochmans, K., Cools, W. & Wissing, K. M., Jan 2022, In: American Journal of Kidney Diseases. 79, 1, p. 79-87.e1 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Dialysis Solutions 100%
  • Citric Acid 94%
  • Heparin 78%
  • Renal Dialysis 75%
  • Blood Volume 35%
  14 Citations (Scopus)

  69 Downloads (Pure)

• Heparin-grafted dialyzer use is safe in case of Heparin-induced thrombocytopenia

  François, K., Orlando, C., Jochmans, K., De Clerck, D., Cambier, M-L., Robberechts, T., Pipeleers, L., Janssens, P. & Wissing, K. M., 1 Feb 2022, (Unpublished).

  Research output: Unpublished contribution to conference › Poster

• Molecular dissection of structural variations involved in antithrombin deficiency

  Morena-Barrio, B. D. L., Orlando, C., Sanchis-Juan, A., García, J. L., Padilla, J., Eugenia de la Morena-Barrio, M., Puruunen, M., Stouffs, K., Cifuentes, R., Borràs, N., Bravo-Pérez, C., Benito, R., Cuenca-Guardiola, J., Vicente, V., Vidal, F., Hernández-Rivas, J. M., Ouwehand, W., Jochmans, K. & Corral, J., May 2022, In: The Journal of Molecular Diagnostics. 24, 5, p. 462-475 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Antithrombins 100%
  • Retroelements 71%
  • Dissection 70%
  • Multiplex Polymerase Chain Reaction 61%
  • Exons 45%
  6 Citations (Scopus)
• 2021

  Antithrombin p.Thr147Ala: The First Founder Mutation in People of African Origin Responsible for Inherited Antithrombin Deficiency

  Orlando, C., de la Morena-Barrio, B., Pareyn, I., Vanhoorelbeke, K., Martínez-Martínez, I., Vicente, V., Corral, J., Jochmans, K. & de la Morena-Barrio, M. E., 1 Feb 2021, In: Thrombosis and Haemostasis. 121, 2, p. 182-191 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Antithrombins 100%
  • Mutation 45%
  • Venous Thromboembolism 25%
  • Haplotypes 21%
  • Heparin 21%
  8 Citations (Scopus)

  37 Downloads (Pure)

• A pilot study on the impact of congenital thrombophilia in COVID-19

  de la Morena-Barrio, M. E., Bravo-Pérez, C., de la Morena-Barrio, B., Orlando, C., Cifuentes, R., Padilla, J., Miñano, A., Herrero, S., Marcellini, S., Revilla, N., Bernal, E., Gómez-Verdú, J. M., Jochmans, K., Herranz, M. T., Vicente, V., Corral, J. & Lozano, M. L., May 2021, In: European Journal of Clinical Investigation. 51, 5, 8 p., e13546.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  17 Citations (Scopus)

• Novel insights in inherited antithrombin deficiency: from laboratory diagnosis to clinical presentation

  Orlando, C., 2021, ASP / VUBPRESS. 164 p.

  Research output: Thesis › PhD Thesis

  • Antithrombins 100%
  • Clinical Laboratory Techniques 91%

• Thrombotic storm under DOAC treatment in a patient with homozygous antithrombin Budapest III mutation

  Condoluci, A., Alberio, L., Gomez, F-J., Studt, J-D., Orlando, C., Jochmans, K. & Gerber, B., May 2021, In: Thrombosis Research. 201, p. 161-163 3 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• TTP during Pregnancy: Acquired or Late-Onset Congenital? A Diagnostic Challenge

  Demeester, S., De Beule, N., Orlando, C., De Becker, A. & Jochmans, K., 2021, In: Research and Practice in Thrombosis and Haemostasis. 5, suppl 2, PB0849.

  Research output: Contribution to journal › Meeting abstract (Journal)
• 2020

  Antithrombin deficiency: look back on type 2 Heparin Binding Site in CHU de Charleroi.

  Goudji, C., Jochmans, K., Orlando, C., Stouffs, K., Tamigneau, A., Jurdan, M. & Cauchie, P., 26 Nov 2020.

  Research output: Unpublished contribution to conference › Poster

• Characterisation of antithrombin p.Thr147Ala, the first common founder variant from African origin responsible for inherited antithrombin deficiency

  de la Morena-Barrio, B., Padilla, J., Pareyn, I., Bravo-Perez, C., Vanhoorelbeke, K., Martinez-Martinez, I., Vicente, V., Corral, J., Jochmans, K., de la Morena-Barrio, M-E. & Orlando, C., 2020, In: Research and Practice in Thrombosis and Haemostasis. 4, Suppl 1, p. 1121-1122 2 p.

  Research output: Contribution to journal › Meeting abstract (Journal)

• Characterisation of antithrombin p.Thr147Ala, the first common founder variant from African origin responsible for inherited antithrombin deficiency

  de la Morena-Barrio, B., Padilla, J., Pareyn, I., Bravo-Perez, C., Vanhoorelbeke, K., Martinez-Martinez, I., Vicente, V., Corral, J., Jochmans, K., de la Morena-Barrio, M-E. & Orlando, C., 2020.

  Research output: Unpublished contribution to conference › Poster

• Disseminated intravascular coagulation and stroke under DOAC treatment in a patient with homozygous antithrombin Budapest III mutation

  Condoluci, A., Studt, D-J., Orlando, C., Jochmans, K. & Gerber, B., 2020.

  Research output: Unpublished contribution to conference › Poster

• Evaluation of DOAC Remove for the measurement of thrombophilia screening parameters in patients treated with direct anti-Xa oral anticoagulants.

  Evenepoel, A., Orlando, C. & Jochmans, K., 2020, In: Belgian Journal of Hematology. 1, Suppl 1, p. 89-89 1 p.

  Research output: Contribution to journal › Meeting abstract (Journal)

• Functional characterization of antithrombin p.Thr147Ala: not just another SNP?

  Orlando, C., de la Morena-Barrio, M-E., Pareyn, I., Vanhoorelbeke, K., Corral, J. & Jochmans, K., 2020, In: Belgian Journal of Hematology. 1, Suppl 1, p. 90-90 1 p.

  Research output: Contribution to journal › Meeting abstract (Journal)

• Hemodialysis Does Not Induce Detectable Activation of the Contact System of Coagulation

  François, K., Orlando, C., Jochmans, K., Cools, W., De Meyer, V., Tielemans, C. & Wissing, K. M., Jun 2020, In: Kidney international reports. 5, 6, p. 831-838 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dialyzer 100%
  • Prothrombin 85%
  • Coagulation 67%
  • antithrombin III-protease complex 65%
  • Renal Dialysis 57%
  13 Citations (Scopus)

• Recommendations for clinical laboratory testing for antithrombin deficiency; Communication from the SSC of the ISTH

  Van Cott, E., Orlando, C., Moore, G., Cooper, P., Meijer, P. & Marlar, R., 1 Jan 2020, In: Journal of Thrombosis and Haemostasis. 18, 1, p. 17-22 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Antithrombins 100%
  • Clinical Laboratory Techniques 91%
  • betrixaban 76%
  • Factor IIa 69%
  • Antithrombin III Deficiency 64%
  71 Citations (Scopus)

• Routine haematology parameters in COVID-19 patients and clinical outcome: A Belgian single-centre study

  Demeester, S., Demuyser, T., Fauconnier, C., Heestermans, R., Orlando, C., Depreter, B. & Jochmans, K., Dec 2020, In: International Journal of Laboratory Hematology. 42, 6, p. e252-e255 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)
• 2019

  ABSENCE OF MEASURABLE CONTACT SYSTEM ACTIVATION OF COAGULATION DURING HAEMODIALYSIS: A RANDOMIZED CROSSOVER STUDY

  Francois, K., Orlando, C., Jochmans, K., De Meyer, V., Tielemans, C. & Wissing, K. M., Jun 2019, In: Nephrology Dialysis Transplantation. 34, suppl 1, p. i20-i21 2 p.

  Research output: Contribution to journal › Meeting abstract (Journal)

• Absence of measurable contact system activation of coagulation during hemodialysis: a randomized crossover study

  Orlando, C., François, K., Jochmans, K., De Meyer, V., Tielemans, C. & Wissing, K. M., 9 Jul 2019.

  Research output: Unpublished contribution to conference › Poster

• Absence of Measurable Contact System Activation of Coagulation during Hemodialysis: A Randomized Crossover Study

  Orlando, C., François, K., De Meyer, V., Jochmans, K., Tielemans, C. & Wissing, K. M., 21 Jun 2019, In: Research and Practice in Thrombosis and Haemostasis. 3, S1, PB1256.

  Research output: Contribution to journal › Meeting abstract (Journal)

  Open Access

  • prothrombin fragment 1 100%
  • prothrombin fragment 2 97%
  • Cross-Over Studies 81%
  • Renal Dialysis 77%
  • Kallikreins 42%
  2 Citations (Scopus)

• Effective inhibition of contact activation pathway of coagulation during hemodialysis using systemic heparin anticoagulation: a randomized crossover study

  François, K., Wissing, K. M., Tielemans, C., De Meyer, V., Jochmans, K. & Orlando, C., 2019.

  Research output: Unpublished contribution to conference › Poster

• Evaluation of DOAC Remove for the measurement of thrombophilia screening parameters in patients treated with direct anti-Xa oral anticoagulants

  Evenepoel, A., Orlando, C. & Jochmans, K., 2019.

  Research output: Unpublished contribution to conference › Poster

• Evaluation of DOAC Remove for the measurement of thrombophilia screening parameters in patients treated with direct anti-Xa oral anticoagulants

  Evenepoel, A., Orlando, C. & Jochmans, K., 2019.

  Research output: Unpublished contribution to conference › Poster

• Functional characterization of antithrombin p.Thr147Ala: not just another SNP?

  Orlando, C., de la Morena-Barrio, M-E., Pareyn, I., Vanhoorelbeke, K., Corral, J. & Jochmans, K., 2019.

  Research output: Unpublished contribution to conference › Poster

• Incidence and features of thrombosis in children with inherited antithrombin deficiency

  de la Morena-Barrio, B., Orlando, C., de la Morena-Barrio, M. E., Vicente, V., Jochmans, K. & Corral, J., Dec 2019, In: Haematologica. 104, 12, p. 2512-2518 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Antithrombins 100%
  • Thrombosis 63%
  • Incidence 39%
  • Child 35%
  • Pediatrics 30%
  27 Citations (Scopus)
• 2018

  Child-onset thrombotic thrombocytopenic purpura caused by p.R498C and p.G259PfsX133 mutations in ADAMTS13

  Schelpe, A-S., Orlando, C., Ercig, B., Geeroms, C., Pareyn, I., Vandeputte, N., Velásquez Pereira, L. C., Roose, E., Fostier, K., Nicolaes, G. A. F., Deckmyn, H., De Meyer, S. F., Vanhoorelbeke, K. & Jochmans, K., Aug 2018, In: European Journal of Haematology. 101, 2, p. 191-199 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Thrombotic Thrombocytopenic Purpura 100%
  • Mutation 41%
  • Child 32%
  • Enzyme-Linked Immunosorbent Assay 13%
  • Antigens 11%
  6 Citations (Scopus)

• Evaluation of the cobas t 711 coagulation analyzer: a single center experience

  Orlando, C., Damiaens, S., Belce, O. & Jochmans, K., 2018, p. 1-1. 1 p.

  Research output: Unpublished contribution to conference › Poster

• Evaluation of the cobas t 711 coagulation analyzer: a single center experience

  Orlando, C., Damiaens, S., Belce, O. & Jochmans, K., 2018, In: Belgian Journal of Hematology. 1, Suppl 1, p. 1-1 1 p.

  Research output: Contribution to journal › Meeting abstract (Journal)

• Heterozygous FGA p.Asp473Ter (fibrinogen Nieuwegein) presenting as antepartum cerebral thrombosis

  Tajdar, M., Orlando, C., Casini, A., Herpol, M., De Bisschop, B., Govaert, P., Neerman-Arbez, M. & Jochmans, K., Mar 2018, In: Thrombosis Research. 163, p. 185-189 5 p.

  Research output: Contribution to journal › Article › peer-review

  • fibrinogen Nieuwegein 100%
  • Intracranial Thrombosis 53%
  • Fibrinogen 38%
  • Thrombin Time 27%
  • Hemostatics 21%
  7 Citations (Scopus)

• Inherited antithrombin deficiency and thrombosis in childhood: data from a large multicentric cohort

  Orlando, C., de la Morena-Barrio, B., de la Morena-Barrio, M-E., Vicente, V., Corral, J. & Jochmans, K., 2018, In: Belgian Journal of Hematology. 1, Suppl 1, p. 1-1 1 p.

  Research output: Contribution to journal › Meeting abstract (Journal)
• 2017

  Acquired Haemophilia A

  Van der Beken, Y., Orlando, C., Fostier, K. & Jochmans, K., Mar 2017, p. 49. 1 p.

  Research output: Unpublished contribution to conference › Poster

• Antithrombin p.Thr147AIa: not just another SNP?

  Orlando, C., Pareyn, I., Schelpe, A-S., Vanhoorelbeke, K. & Jochmans, K., 2017, (Unpublished).

  Research output: Unpublished contribution to conference › Poster

• Antithrombin p.Thr147Ala: not just another SNP?

  Orlando, C., Pareyn, I., Schelpe, A-S., Vanhoorelbeke, K. & Jochmans, K., 2017, In: Research and Practice in Thrombosis and Haemostasis. 1, Suppl 1, 1 p.

  Research output: Contribution to journal › Meeting abstract (Journal)

• A suspected torn soleus muscle as presenting manifestation of acquired haemophilia A: a diagnostic pitfall

  Van der Beken, Y., Orlando, C., Fostier, K. & Jochmans, K., Mar 2017, p. S119. 1 p.

  Research output: Unpublished contribution to conference › Poster

• A suspected torn soleus muscle as presenting manifestation of acquired haemophilia A: a diagnostic pitfall

  Van der Beken, Y. A., Orlando, C., Fostier, K. & Jochmans, K., 2017, In: Belgian Journal of Hematology. 1, Suppl 1, 1 p.

  Research output: Contribution to journal › Meeting abstract (Journal)

• A suspected torn soleus muscle as presenting manifestation of acquired haemophilia A: a diagnostic pitfall

  Van der Beken, Y. A., Orlando, C., Fostier, K. & Jochmans, K., 2017, In: Thrombosis Research. 151, Suppl 1, 1 p.

  Research output: Contribution to journal › Meeting abstract (Journal)

• The p.Arg498Cys mutation in the cysteine rich domain of ADAMTS13 results in a secretion deficiency

  Schelpe, A-S., Orlando, C., Geeroms, C., Pareyn, I., Vandeputte, N., Deckmyn, H., Jochmans, K., De Meyer, S. & Vanhoorelbeke, K., 2017, In: Belgian Journal of Hematology. 1, Suppl 1, 1 p.

  Research output: Contribution to journal › Meeting abstract (Journal)
• 2016

  A novel FGA mutation underlying a case of congenital dysfibrinogenemia with unusual clinical presentation.

  Tajdar, M., Herpol, M., Orlando, C., De Bisschop, B., Govaert, P. & Jochmans, K., 2016, In: Belgian Journal of Hematology. 4, p. 14 1 p.

  Research output: Contribution to journal › Meeting abstract (Journal)