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Collaborations and top research areas from the last five years
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Cryo-EM structures of the MnmE-MnmG complex reveal large conformational changes and provide new insights into the mechanism of tRNA modification
Maes, L., Mares-Mejía, I., Martin, E., Bickel, D., Claeys, S., Vranken, W., Fislage, M., Galicia, C. & Versées, W., 9 Sept 2025, In: Nucleic Acids Research. 53, 16, 17 p., gkaf824.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity
Martin, E., Giakoumakis, D., Paesmans, J., Bisi, N., Drozdzecki, A., Audenaert, D., Haustraete, J., Verstreken, P., Galicia, C., Ballet, S. & Versées, W., 12 Sept 2025, In: ACS Pharmacology and Translational Science. 8, 9, p. 2996-3006 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Synaptojanin1: From Structural Insights to Therapeutic Targeting
Martin, E., Paesmans, J., Berghmans, M., Giakoumakis, D., Galicia Diaz Santana, C. & Versées, W., 2025.Research output: Unpublished contribution to conference › Poster
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A designed ankyrin-repeat protein that targets Parkinson's disease-associated LRRK2
Dederer, V., Sanz Murillo, M., Karasmanis, E. P., Hatch, K. S., Chatterjee, D., Preuss, F., Abdul Azeez, K. R., Vu Nguyen, L., Galicia, C., Dreier, B., Plückthun, A., Versees, W., Mathea, S., Leschziner, A. E., Reck-Peterson, S. L. & Knapp, S., Jul 2024, In: Journal of Biological Chemistry. 300, 7, 14 p., 107469.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)198 Downloads (Pure) -
Characterization of effects of LRRK2 binding nanobodies on LRRK2 heterologous phosphorylation.
Annicotte, C., Galicia Diaz Santana, C., Dal Maso, T., Versées, W. & Taymans, J.-M., 18 Jun 2024.Research output: Unpublished contribution to conference › Poster
Datasets
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YbiB: a Novel Interactor of the GTPase ObgE
Deckers, B. (Creator), Vercauteren, S. (Creator), De Kock, V. (Creator), Martin, C. (Creator), Lazar, T. (Creator), Herpels, P. (Creator), Dewachter, L. (Creator), Verstraeten, N. (Creator), Peeters, E. (Creator), Ballet, S. (Creator), Michiels, J. (Creator), Galicia Diaz Santana, C. (Creator) & Versées, W. (Creator), Zenodo, 8 Nov 2022
Dataset
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Crystal structure of the E. coli TrpD2 protein in complex with a C-terminal peptide from ObgE
Deckers, B. (Creator), Galicia Diaz Santana, C. (Creator) & Versées, W. (Creator), Protein Data Bank, 22 Feb 2023
Dataset
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Crystal structure of the E. coli TrpD2 protein YbiB at 1.3 A resolution
Deckers, B. (Creator), Galicia Diaz Santana, C. (Creator) & Versées, W. (Creator), Protein Data Bank, 22 Feb 2023
Dataset
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Focused map on the Roc-COR domains of the Roco protein from C. tepidum in the GTP state bound to the activating Nanobody NbRoco1
Versées, W. (Creator) & Galicia Diaz Santana, C. (Creator), Protein Data Bank, 1 May 2024
DOI: 10.2210/pdb8R4D/pdb
Dataset
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LRR domain of Roco protein from C. tepidum bound to the activating Nanobody NbRoco2
Versées, W. (Creator) & Galicia Diaz Santana, C. (Creator), Protein Data Bank, 1 May 2024
DOI: 10.2210/pdb8R4C/pdb
Dataset
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Structural insights in the GTP-driven monomerization and activation of a bacterial LRRK2 homologue using allosteric nanobodies.
Versées, W. (Contributor) & Galicia Diaz Santana, C. (Speaker)
18 Jun 2024 → 21 Jun 2024Activity: Talk or presentation › Talk or presentation at a conference
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Deciphering the interactome of ObgE: a widely conserved GTPase acting at the crossroads of cell survival and cell death (Event)
Versées, W. (Supervisor), Deckers, B. (Presenter) & Galicia Diaz Santana, C. (Advisor)
1 Mar 2024Activity: Membership › Member of PhD committee
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PhD defence of Jone Paesmans: "Unraveling the structure and function of the synaptic proteins TBC1D24 and Synaptojanin1 and their role in neurological disorders" (Event)
Ballet, S. (Jury), Brunner, J. (Jury), Smolders, I. (Jury), Greggio, E. (Jury), Ismail, S. (Jury) & Galicia Diaz Santana, C. (Advisor)
29 Jun 2021Activity: Membership › Member of PhD committee
Thesis
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Genetically-encoded fluorescent indicators for the detection of reactive sulfur species
Claude, O. ((PhD) Student), Messens, J. (Promotor), Ezeriņa, D. (Co-promotor), Galicia Diaz Santana, C. (Jury) & Peeters, E. (Jury), 8 Sept 2025Student thesis: Master's Thesis