Projects per year
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Projects
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FWOTM1016: The impact of recurrent chromosomal abnormalities on growth advantage and differentiation capacity of human pluripotent stem cells
1/11/20 → 31/10/22
Project: Fundamental
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HERC53: Seahorse platform: the Agilent Seahorse Flux Analyser with integrated normalization system
Massie, A., Stiens, J., Van Ginderachter, J., Vanommeslaeghe, K., Vinken, M., Menu, E., Spits, C. & Njemini, R.
1/05/20 → 30/04/24
Project: Fundamental
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OZR3565: Seahorse platform: the Agilent Seahorse Flux Analyser with integrated normalization system
Massie, A., Stiens, J., Van Ginderachter, J., Vanommeslaeghe, K., Vinken, M., Menu, E., Spits, C. & Njemini, R.
1/05/20 → 30/04/24
Project: Fundamental
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FWOTM968: The search for the origin of chromosomal abnormalities in human preimplantation embryos
Sermon, K., Spits, C. & Regin, M.
1/10/19 → 31/10/21
Project: Fundamental
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FWOAL877: The search for the origin of chromosomal abnormalities in human preimplantation embryos
1/01/18 → 31/12/21
Project: Fundamental
Research output
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MSH2 knock-down shows CTG repeat stability and concomitant upstream demethylation at the DMPK locus in myotonic dystrophy type 1 human embryonic stem cells
Franck, S., Barbé, L., Ardui, S., De Vlaeminck, Y., Allemeersch, J., Dziedzicka, D., Spits, C., Vanroye, F., Hilven, P., Duqué, G., Vermeesch, J. R., Gheldof, A. & Sermon, K., 6 Jan 2021, In : Human Molecular Genetics. 29, 21, p. 3566-3577 12 p.Research output: Contribution to journal › Article
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Detection of Heteroplasmic Variants in the Mitochondrial Genome through Massive Parallel Sequencing
Mertens, J., Zambelli, F., Daneels, D., Caljon, B., Sermon, K. & Spits, C., 5 Jul 2019, In : bio-protocol. 9, 13, 7 p., e3283.Research output: Contribution to journal › Article
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Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment.
Markouli, C., Couvreu De Deckersberg, E., Regin, M., Nguyen Thi, H., Zambelli, F., Keller, A. S., Dziedzicka, D., De Kock, J., Tilleman, L., Van Nieuwerburgh, F., Franceschini, L., Sermon, K., Geens, M. & Spits, C., 9 Jul 2019, In : Stem Cell Reports. 13, 1, p. 163-176 14 p.Research output: Contribution to journal › Article
Open Access8 Citations (Scopus) -
Gains of chromosome 12p13.31 inhibit exit of pluripotency during hepatic differentiation of human pluripotent stem cells
Keller, A. S., Dziedzicka, D. A., Franck, S., Markouli, C., Sermon, K., Spits, C. & Geens, M., 27 Jun 2019, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Gains of chromosome 12p13.31 inhibit exit of pluripotency during hepatic differentiation of human pluripotent stem cells
Keller, A. S., Dziedzicka, D. A., Franck, S., Markouli, C., Sermon, K., Spits, C. & Geens, M., 13 Sep 2019, (Unpublished).Research output: Unpublished contribution to conference › Poster
Activities
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Mitochondrial DNA mosaicism in early human development
Joke Mertens (Speaker), Marius Regin (Contributor), Neelke De Munck (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor), Claudia Spits (Contributor)25 Jun 2019Activity: Talk or presentation › Talk or presentation at a conference
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Mitochondrial DNA mosaicism in early human development
Joke Mertens (Speaker), Marius Regin (Contributor), Neelke De Munck (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor), Christophe Blockeel (Contributor), Claudia Spits (Contributor)22 Nov 2019 → 23 Nov 2019Activity: Talk or presentation › Talk or presentation at a conference
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Mitochondrial DNA variants in individuals born after ART compared to spontaneously conceived peers
Joke Mertens (Speaker), Filippo Zambelli (Contributor), Florence Belva (Contributor), Aafke PA van Montfoort (Contributor), Mary-Louise Bonduelle (Contributor), Sara Seneca (Contributor), Karen Sermon (Contributor), Claudia Spits (Contributor)24 Nov 2018Activity: Talk or presentation › Talk or presentation at a conference
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Increased heteroplasmic load of coding mitochondrial DNA variants in tissues from ART children
Joke Mertens (Speaker), Filippo Zambelli (Contributor), Florence Belva (Contributor), Aafke PA van Montfoort (Contributor), Mary-Louise Bonduelle (Contributor), Sara Seneca (Contributor), Karen Sermon (Contributor), Claudia Spits (Contributor)3 Jul 2018Activity: Talk or presentation › Talk or presentation at a conference
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Mitochondrial DNA variants in individuals born after ART compared to spontaneously conceived peers
Joke Mertens (Speaker), Filippo Zambelli (Contributor), Florence Belva (Contributor), Aafke PA van Montfoort (Contributor), Mary-Louise Bonduelle (Contributor), Sara Seneca (Contributor), Karen Sermon (Contributor), Claudia Spits (Contributor)12 Oct 2018Activity: Talk or presentation › Talk or presentation at a conference
Press / Media
Thesis
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(R)evolution in preimplantation genetic diagnosis : development and clinical application of different approaches to preimplantation genetic diagnosis for monogenic disorders.
Author: Spits, C., Liebaers, I., Sermon, K., De Rycke, M., Van Schravendijk, C., Van Der Auwera, B., Geraedts, J., Harper, J., Santalo Pedro, J., De Paepe, A., Legius, E. & Timmerman, V., 4 Dec 2006Supervisor: Liebaers, I. (Promotor), Sermon, K. (Co-promotor), De Rycke, M. (Co-promotor), Van Schravendijk, C. (Jury), Van Der Auwera, B. (Jury), Geraedts, J. (External person) (Jury), Harper, J. (External person) (Jury), Santalo Pedro, J. (External person) (Jury), De Paepe, A. (External person) (Jury), Legius, E. (External person) (Jury) & Timmerman, V. (External person) (Jury)
Student thesis: Doctoral Thesis
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Analysis of mitochondrial DNA variants in ART and spontaneously conceived individuals
Author: Rhioui, K., Mertens, J. & Spits, C., 6 Sep 2018Supervisor: Spits, C. (Promotor)
Student thesis: Master's Thesis
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Characterisation of the molecular causes and selective advantages of chromosome abnormalities in human embryonic stem cells
Author: Nguyen Thi, H., Sermon, K. & Spits, C., 2 Sep 2010Supervisor: Sermon, K. (Promotor) & Spits, C. (Advisor)
Student thesis: Master's Thesis
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Chromosomal abnormalities in human preimplantation development
Author: Mertzanidou, A., Spits, C., Sermon, K., Van Schravendijk, C., Breckpot, K., De Rycke, M., Verpoest, W., Wells, D. & Debrock, S., 29 Apr 2015Supervisor: Sermon, K. (Promotor), Spits, C. (Promotor), Van Schravendijk, C. (Jury), Breckpot, K. (Jury), De Rycke, M. (Jury), Verpoest, W. (Jury), Wells, D. (External person) (Jury) & Debrock, S. (External person) (Jury)
Student thesis: Doctoral Thesis
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DNA damage in hESC cultured on feeder-free conditions: the impact of cell density
Author: Ivanna, I., Spits, C. & Jacobs, K., 3 Sep 2014Supervisor: Spits, C. (Promotor) & Jacobs, K. (Co-promotor)
Student thesis: Master's Thesis