Claudia Spits

Academic, Basic (bio-) Medical Sciences
Reproduction and Genetcis

Laarbeeklaan 103
1090 Brussels
Belgium

Source: Scopus
Calculated based on no. of publications stored in Pure and citations from Scopus

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6 Active
20 Finished

FWOTM1016: The impact of recurrent chromosomal abnormalities on growth advantage and differentiation capacity of human pluripotent stem cells
Krivec, N. & Spits, C.
1/11/20 → 31/10/22
Project: Fundamental
HERC53: Seahorse platform: the Agilent Seahorse Flux Analyser with integrated normalization system
Massie, A., Stiens, J., Van Ginderachter, J., Vanommeslaeghe, K., Vinken, M., Menu, E., Spits, C. & Njemini, R.
1/05/20 → 30/04/24
Project: Fundamental
OZR3565: Seahorse platform: the Agilent Seahorse Flux Analyser with integrated normalization system
Massie, A., Stiens, J., Van Ginderachter, J., Vanommeslaeghe, K., Vinken, M., Menu, E., Spits, C. & Njemini, R.
1/05/20 → 30/04/24
Project: Fundamental
FWOTM968: The search for the origin of chromosomal abnormalities in human preimplantation embryos
Sermon, K., Spits, C. & Regin, M.
1/10/19 → 31/10/21
Project: Fundamental
FWOAL877: The search for the origin of chromosomal abnormalities in human preimplantation embryos
Sermon, K. & Spits, C.
1/01/18 → 31/12/21
Project: Fundamental

1891 Citations
22 h-Index
48 Article
24 Meeting abstract (Book)
11 Poster
11 Meeting abstract (Journal)
More
- 10 Unpublished abstract
- 2 Scientific review

MSH2 knock-down shows CTG repeat stability and concomitant upstream demethylation at the DMPK locus in myotonic dystrophy type 1 human embryonic stem cells
Franck, S., Barbé, L., Ardui, S., De Vlaeminck, Y., Allemeersch, J., Dziedzicka, D., Spits, C., Vanroye, F., Hilven, P., Duqué, G., Vermeesch, J. R., Gheldof, A. & Sermon, K., 6 Jan 2021, In : Human Molecular Genetics. 29, 21, p. 3566-3577 12 p.
Research output: Contribution to journal › Article
Detection of Heteroplasmic Variants in the Mitochondrial Genome through Massive Parallel Sequencing
Mertens, J., Zambelli, F., Daneels, D., Caljon, B., Sermon, K. & Spits, C., 5 Jul 2019, In : bio-protocol. 9, 13, 7 p., e3283.
Research output: Contribution to journal › Article
Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment.
Markouli, C., Couvreu De Deckersberg, E., Regin, M., Nguyen Thi, H., Zambelli, F., Keller, A. S., Dziedzicka, D., De Kock, J., Tilleman, L., Van Nieuwerburgh, F., Franceschini, L., Sermon, K., Geens, M. & Spits, C., 9 Jul 2019, In : Stem Cell Reports. 13, 1, p. 163-176 14 p.
Research output: Contribution to journal › Article

Open Access
8 Citations (Scopus)
Gains of chromosome 12p13.31 inhibit exit of pluripotency during hepatic differentiation of human pluripotent stem cells
Keller, A. S., Dziedzicka, D. A., Franck, S., Markouli, C., Sermon, K., Spits, C. & Geens, M., 27 Jun 2019, (Unpublished).
Research output: Unpublished contribution to conference › Poster
Gains of chromosome 12p13.31 inhibit exit of pluripotency during hepatic differentiation of human pluripotent stem cells
Keller, A. S., Dziedzicka, D. A., Franck, S., Markouli, C., Sermon, K., Spits, C. & Geens, M., 13 Sep 2019, (Unpublished).
Research output: Unpublished contribution to conference › Poster

5 Talk or presentation at a conference
4 Participation in conference
3 Talk or presentation at a workshop/seminar
1 Participation in workshop, seminar

Mitochondrial DNA mosaicism in early human development
Joke Mertens (Speaker), Marius Regin (Contributor), Neelke De Munck (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor), Claudia Spits (Contributor)
25 Jun 2019
Activity: Talk or presentation › Talk or presentation at a conference
Mitochondrial DNA mosaicism in early human development
Joke Mertens (Speaker), Marius Regin (Contributor), Neelke De Munck (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor), Christophe Blockeel (Contributor), Claudia Spits (Contributor)
22 Nov 2019 → 23 Nov 2019
Activity: Talk or presentation › Talk or presentation at a conference
Mitochondrial DNA variants in individuals born after ART compared to spontaneously conceived peers
Joke Mertens (Speaker), Filippo Zambelli (Contributor), Florence Belva (Contributor), Aafke PA van Montfoort (Contributor), Mary-Louise Bonduelle (Contributor), Sara Seneca (Contributor), Karen Sermon (Contributor), Claudia Spits (Contributor)
24 Nov 2018
Activity: Talk or presentation › Talk or presentation at a conference
Increased heteroplasmic load of coding mitochondrial DNA variants in tissues from ART children
Joke Mertens (Speaker), Filippo Zambelli (Contributor), Florence Belva (Contributor), Aafke PA van Montfoort (Contributor), Mary-Louise Bonduelle (Contributor), Sara Seneca (Contributor), Karen Sermon (Contributor), Claudia Spits (Contributor)
3 Jul 2018
Activity: Talk or presentation › Talk or presentation at a conference
Mitochondrial DNA variants in individuals born after ART compared to spontaneously conceived peers
Joke Mertens (Speaker), Filippo Zambelli (Contributor), Florence Belva (Contributor), Aafke PA van Montfoort (Contributor), Mary-Louise Bonduelle (Contributor), Sara Seneca (Contributor), Karen Sermon (Contributor), Claudia Spits (Contributor)
12 Oct 2018
Activity: Talk or presentation › Talk or presentation at a conference

Stamcelonderzoek: fouten opstapelen
Claudia Spits
8/04/09
1 Media contribution
Press/Media: Other
Betere screening van embryonale stamcellen
Claudia Spits
1/04/09
1 Media contribution
Press/Media: Other

(R)evolution in preimplantation genetic diagnosis : development and clinical application of different approaches to preimplantation genetic diagnosis for monogenic disorders.
Author: Spits, C., Liebaers, I., Sermon, K., De Rycke, M., Van Schravendijk, C., Van Der Auwera, B., Geraedts, J., Harper, J., Santalo Pedro, J., De Paepe, A., Legius, E. & Timmerman, V., 4 Dec 2006
Supervisor: Liebaers, I. (Promotor), Sermon, K. (Co-promotor), De Rycke, M. (Co-promotor), Van Schravendijk, C. (Jury), Van Der Auwera, B. (Jury), Geraedts, J. (External person) (Jury), Harper, J. (External person) (Jury), Santalo Pedro, J. (External person) (Jury), De Paepe, A. (External person) (Jury), Legius, E. (External person) (Jury) & Timmerman, V. (External person) (Jury)
Student thesis: Doctoral Thesis
Analysis of mitochondrial DNA variants in ART and spontaneously conceived individuals
Author: Rhioui, K., Mertens, J. & Spits, C., 6 Sep 2018
Supervisor: Spits, C. (Promotor)
Student thesis: Master's Thesis
Characterisation of the molecular causes and selective advantages of chromosome abnormalities in human embryonic stem cells
Author: Nguyen Thi, H., Sermon, K. & Spits, C., 2 Sep 2010
Supervisor: Sermon, K. (Promotor) & Spits, C. (Advisor)
Student thesis: Master's Thesis
Chromosomal abnormalities in human preimplantation development
Author: Mertzanidou, A., Spits, C., Sermon, K., Van Schravendijk, C., Breckpot, K., De Rycke, M., Verpoest, W., Wells, D. & Debrock, S., 29 Apr 2015
Supervisor: Sermon, K. (Promotor), Spits, C. (Promotor), Van Schravendijk, C. (Jury), Breckpot, K. (Jury), De Rycke, M. (Jury), Verpoest, W. (Jury), Wells, D. (External person) (Jury) & Debrock, S. (External person) (Jury)
Student thesis: Doctoral Thesis
DNA damage in hESC cultured on feeder-free conditions: the impact of cell density
Author: Ivanna, I., Spits, C. & Jacobs, K., 3 Sep 2014
Supervisor: Spits, C. (Promotor) & Jacobs, K. (Co-promotor)
Student thesis: Master's Thesis