Projects per year
Personal profile
Expertise
My passion to unravel the mysteries of human biology resulted in expertise on three main levels: (1) antitumor immunotherapy with focus on lung cancer and melanoma, (2) applications with lentiviral vectors such as cell line modifications next to vaccination and (3) development of threedimensional tumor immunology models to disclose fundamental keys of tumor resistance to immunotherapy.
External positions
Postdoctoral researcher, Icahn School of Medicine at Mount Sinai
14 Nov 2016 → 30 Nov 2017
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Dive into the research topics where Cleo Goyvaerts is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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FWOAL1006: Creation of a 3D CRiMe scene to unravel Cytotoxicity Resistant Mechanisms in non-small cell lung cancer
Goyvaerts, C. (Administrative Promotor)
1/01/21 → 31/12/24
Project: Fundamental
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BRGRD44: Joint R&D 2020: "IMPACT: Invigorating precision Medicine by Predictive imaging of sdAb-based anti-Cancer Theranostics"
Lahoutte, T. (Administrative Promotor), Keyaerts, M. (Administrative Promotor), Krasniqi, A. (CoI (Co-Promotor)), Breckpot, K. (Administrative Promotor) & Goyvaerts, C. (CoI (Co-Promotor))
1/07/20 → 30/06/24
Project: Applied
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ANI250: Evaluating 3D² tumor spheroids as a tool to study tumor-immune cell interactions
Breckpot, K. (Administrative Promotor) & Goyvaerts, C. (Collaborator)
1/01/20 → 31/12/20
Project: Fundamental
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FWOKN302: Target and explore the ‘X factor’ of the lung tumor microenvironment.
Goyvaerts, C. (Administrative Promotor), Breckpot, K. (PI (Promotor, Principal Investigator)) & Thielemans, K. (PI (Promotor, Principal Investigator))
1/01/18 → 31/12/18
Project: Fundamental
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ANI160: Beurs Emmanuel Van der Schueren: The Trojan Horse: an old strategy coming of age to explore and defeat tumors from within
Breckpot, K. (Administrative Promotor) & Goyvaerts, C. (Co-Promotor)
1/10/16 → 30/09/19
Project: Fundamental
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Development of the nanobody display technology to target lentiviral vectors to antigen-presenting cells
Goyvaerts, C., De Groeve, K., Dingemans, J., Van Lint, S., Robays, L., Heirman, C., Reiser, J., Zhang, X.-Y., Thielemans, K., De Baetselier, P., Raes, G. & Breckpot, K., 12 Jan 2012, In: Gene Therapy. 19, p. 1133-1140Research output: Contribution to journal › Article › peer-review
Open Access65 Citations (Scopus) -
Immunogenicity of targeted lentivectors
Goyvaerts, C., De Groeve, K., Van Lint, S., Heirman, C., Van Ginderachter, J., De Baetselier, P., Raes, G., Thielemans, K. & Breckpot, K., 19 Jan 2014, In: Oncotarget. 5, p. 704-715 12 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Citations (Scopus) -
Turn Back the TIMe: Targeting Tumor Infiltrating Myeloid Cells to Revert Cancer Progression
Awad, R. M., De Vlaeminck, Y., Maebe, J., Goyvaerts, C. & Breckpot, K., 31 Aug 2018, In: Front Immunol.. 9, p. 1977 1 p., 1977.Research output: Contribution to journal › Scientific review › peer-review
Open Access137 Citations (Scopus) -
Towards a personalized iPSC-based vaccine
Breckpot, K. & Goyvaerts, C., 2 May 2018, In: Nature Biomedical Engineering. 2, 5, p. 277-278 2 p.Research output: Contribution to journal › Comment/debate
Open Access10 Citations (Scopus) -
Unraveling the resistance mechanisms of lung cancer to immunotherapy.
Goyvaerts, C., Agudo, J., Wroblewska, O. & Brown, B., 20 Oct 2017, PRIISM Retreat of Institute of Immunology of the Icahn School of Medicine. New York Academy of Sciences, New YorkResearch output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)
Datasets
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DataSet-Targeted Radionuclide Therapy with Low and High-Dose Lutetium-177-Labeled Single Domain Antibodies Induces Distinct Immune Signatures in a Mouse Melanoma Model
Ertveldt, T. (Creator), De Beck, L. (Creator), De Ridder, K. (Creator), Locy, H. (Creator), de Mey, W. (Creator), Goyvaerts, C. (Creator), Lecocq, Q. (Creator), Ceuppens, H. (Creator), De Vlaeminck, Y. (Creator), Awad, R. M. (Creator), Keyaerts, M. (Creator), Devoogdt, N. (Creator), D'Huyvetter, M. (Creator), Breckpot, K. (Creator) & Krasniqi, A. (Creator), Zenodo, 16 Dec 2024
Dataset
Prizes
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2020 ILC Foundation Young Investigator Award
Goyvaerts, C. (Recipient), 19 Mar 2020
Prize: Fellowship awarded competitively
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Invited to 2019 Spring Concert by His Majesty the King Filip van België
Goyvaerts, C. (Recipient), 28 Feb 2019
Prize: National/international honour
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Official nominee for 'Wetenschapstalent 2018' by 'New Scientist'
Goyvaerts, C. (Recipient), 2018
Prize: National/international honour
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Immunotools Special Award
Goyvaerts, C. (Recipient), 20 May 2014
Prize: Prize (including medals and awards)
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Belgian American Education Foundation (BAEF) fellowship
Goyvaerts, C. (Recipient), 2016
Prize: Fellowship awarded competitively
Activities
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'Anti-PD-Ll treatment modifies the landscape of specific lung (tumor) residing myeloid cell subsets in vivo'
Goyvaerts, C. (Speaker)
8 Mar 2020 → 11 Mar 2020Activity: Talk or presentation › Talk or presentation at a conference
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ZAP Onderwijsprofessionalisering Nieuwpoort
Goyvaerts, C. (Participant)
7 Jan 2020 → 10 Jan 2020Activity: Participating in or organising an event › Participation in workshop, seminar
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Antitumor immuuntherapie: kanker die zichzelf leert genezen
Goyvaerts, C. (Speaker)
2020 → …Activity: Talk or presentation › Talk at a public lecture/debate
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'The role of experimental animals in cancer immunotherapy research'
Goyvaerts, C. (Speaker)
6 Dec 2019Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Wetenschapsfestival
Goyvaerts, C. (Organiser)
24 Nov 2019Activity: Participating in or organising an event › Participating in or organizing a festival/exhibition
Press/Media
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'10 inspirerende Belgische vrouwen die hun stempel drukten op het jaar 2020'
29/12/20
1 Media contribution
Press/Media: Other
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'VUB-professor Cleo Goyvaerts (34) ontving dit jaar wereldwijd lof voor haar onderzoek naar longkanker'
10/12/20
1 Media contribution
Press/Media: Other
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Toponderzoekster Cleo Goyvaerts (33) geeft vrijdag lezing in thuisgemeente
13/02/20
1 Media contribution
Press/Media: Other
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ANTITUMOR IMMUUNTHERAPIE: KANKER DIE ZICHZELF LEERT GENEZEN
7/01/16
1 Media contribution
Press/Media: Expert Comment
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Heistse Cleo (29) ontvangt beurs van 225.000 euro voor kankeronderzoek
26/11/15
1 Media contribution
Press/Media: Other
Thesis
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Targeting Tumor Infiltrating Myeloid Cells in Non-Small Cell Lung Cancer
Neumann, J. ((PhD) Student), Goyvaerts, C. (Promotor), Breckpot, K. (Co-promotor) & De Ridder, K. (Advisor), 2020Student thesis: Master's Thesis
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Evaluation of the impact of lung tumor infiltrating myeloid cells on anti-PD-L1 therapy
De Ridder, K. ((PhD) Student), Goyvaerts, C. (Promotor) & Breckpot, K. (Co-promotor), 2019Student thesis: Master's Thesis
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Development of human melanoma spheroids for small molecule inhibitor evaluation
Vancampenhout, Y. ((PhD) Student), Goyvaerts, C. (Promotor) & Breckpot, K. (Promotor), 2019Student thesis: Master's Thesis
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Dissecting the biology of tumor-associated macrophages using lentiviral vectors and nanobodies
De Vlaeminck, Y. ((PhD) Student), Breckpot, K. (Promotor) & Goyvaerts, C. (Promotor), 18 Jun 2015Student thesis: Master's Thesis
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Optimization of 3rd generation lentiviral vectors
Breckpot, K. (Promotor) & Nell, C. ((PhD) Student), Goyvaerts, C. (Promotor), 14 Jun 2016Student thesis: Master's Thesis