Projects per year
Personal profile
Expertise
Dimitri De Bundel is a lecturer to the Faculty of Medicine and Pharmacy. He graduated as a Pharmacist (summa cum laude, 2004) and obtained a PhD in Pharmaceutical Sciences (2009). During his PhD he gained expertise in in vivo neurochemistry methods and behavioural analysis. During a postdoctoral research stays in Karolinska Institutet (Sweden, 2009-2011) and Institut Génomique Fonctionelle (France, 2011-2014) he further developed his expertise in techniques for studying the neurobiological basis for cognitive function and mood regulation. He is now a principal investigator at VUB (since 2014) where he is investigating neurotransmitter and neuropeptide systems involved in memory and mood dysfunction. His core expertise lies in behavioural analysis and targeted pharmacological manipulation of brain transmitter systems in neurological and psychiatric disorders.
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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HERC56: Intravital imaging as tool to bridge the gap between macroscopic in vivo imaging and microscopic tissue analysis
Hernot, S., Staels, W., Hellemans, K., Smolders, I., Rooman, I., Devoogdt, N., Menu, E., De Bundel, D., Breckpot, K., De Leu, N., Movahedi, K., D'Huyvetter, M. & De Kock, J.
1/05/22 → 30/04/26
Project: Fundamental
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OZR3913: Cofinancing OZR FWO Hercules MZW - High-parametric single-cell protein profiling in intact tissues
Movahedi, K., van Grunsven, L., Rooman, I., Van Ginderachter, J., Smolders, I., Neyns, B., Vanhaecke, T., Laoui, D., Breckpot, K., De Veirman, K., Stijlemans, B., Van Schependom, J., Magez, S., Goyvaerts, C., De Kock, J., De Leu, N., Massie, A., Hellemans, K., Spits, C., De Bundel, D., De Trez, C., Hernot, S., Van Dooren, S., Aerts, J., Staels, W. & Tuyaerts, S.
25/02/22 → 25/02/26
Project: Fundamental
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FWOAL1042: Investigating the role of astrocytes and noradrenaline as critical regulators of neuronal circuit excitability.
1/01/22 → 31/12/25
Project: Fundamental
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ANI281: Role of neurogenesis in cognitive decline following stroke in co-morbid Alzheimer's dementia
De Bundel, D., Kooijman, R., Gens, R. & De Smet, A.
1/01/21 → 31/12/23
Project: Fundamental
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OZR3588: Financiering FWO hercules: ERA platform: Extended RNA Analysis platform - version 2.0
Rooman, I., Bouwens, L., Heimberg, H., Neyns, B., Vranken, W., Vanhaecke, T., Massie, A., van Grunsven, L., De Bruyne, E., De Bundel, D., Forsyth, R., Breckpot, K., Van Dooren, S., De Kock, J., Njemini, R. & Laoui, D.
1/05/20 → 30/04/24
Project: Fundamental
Research output
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Accelerated HF-rTMS Modifies SERT Availability in the Subgenual Anterior Cingulate Cortex: A Canine [11C] DASB Study on the Serotonergic System
Xu, Y., Kappen, M., Peremans, K., De Bundel, D., Van Eeckhaut, A., Van Laeken, N., De Vos, F., Dobbeleir, A., Saunders, J. H. & Baeken, C., 10 Mar 2022, In : Journal of Clinical Medicine. 11, 6, 12 p., 1531.Research output: Contribution to journal › Article
Open AccessFile17 Downloads (Pure) -
Assessment of gliotransmitter concentrations upon chemogenetic modulation of astroglia in mouse hippocampus
Nestor, L., Sahu, S., De Bundel, D., Van Eeckhaut, A. & Smolders, I., 9 May 2022, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Current Approaches to Monitor Macromolecules Directly from the Cerebral Interstitial Fluid
Custers, M-L., Nestor, L., De Bundel, D., Van Eeckhaut, A. & Smolders, I., 13 May 2022, In : Pharmaceutics. 14, 5, 20 p., 1051.Research output: Contribution to journal › Article
Open AccessFile9 Downloads (Pure) -
Effects of a psychedelic 5-HT2A receptor agonist on anxiety-related behavior and fear processing in mice
Pędzich, B. D., Rubens, S., Sekssaoui, M., Pierre, A., Van Schuerbeek, A., Marin, P., Bockaert, J., Valjent, E., Bécamel, C. & De Bundel, D., Jun 2022, In : Neuropsychopharmacology. 47, 7, p. 1304-1314 11 p.Research output: Contribution to journal › Article
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Higher susceptibility to 6 Hz corneal kindling and lower responsiveness to antiseizure drugs in mouse models of Alzheimer's disease
Vande Vyver, M., Barker-Haliski, M., Aourz, N., Nagels, G., Bjerke, M., Engelborghs, S., De Bundel, D. & Smolders, I., 30 Jun 2022, In : Epilepsia.Research output: Contribution to journal › Article
Prizes
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Hugo d'Haenen Award
Dimitri De Bundel (Recipient), 2 Oct 2015
Prize: Prize (including medals and awards)
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Les Grandes Avancées en Biologie-Santé du Pôle RABELAIS 2017
Dimitri De Bundel (Recipient), 4 May 2017
Prize: Prize (including medals and awards)
Activities
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Nerdland Festival: BrainMan
Dimitri De Bundel (Invited speaker)5 Jun 2022Activity: Talk or presentation › Talk at a festival/exhibition
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Psychedelica - de toekomst van mentaal welzijn?
Dimitri De Bundel (Invited speaker)31 Mar 2022Activity: Talk or presentation › Talk at a public lecture/debate
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Psychoneuroendocrinology (Journal)
Dimitri De Bundel (Peer reviewer)2022 → …Activity: Publication peer-review and editorial work › Publication peer-review
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Modulatie van angst en vrees door een psychedelische serotonine 2A receptor agonist
Dimitri De Bundel (Invited speaker)11 Jun 2021Activity: Talk or presentation › Talk or presentation at a conference
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Boehringer Ingelheim Travel Grant
Robin Gens (Recipient), Dimitri De Bundel (Supervisor), Sylvie De Raedt (Supervisor), Sebastiaan Engelborghs (Supervisor), Ron Kooijman (Supervisor)17 Feb 2021Activity: Other › Written proposal
Press / Media
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Trippen tegen trauma's: zijn psychedelica geneeskrachtig?
4/05/22
1 item of Media coverage
Press/Media: Research
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Kan nieuw onderzoek met algen het zicht van blinden verbeteren?
25/05/21
1 Media contribution
Press/Media: Expert Comment
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Une horloge biologique perturbée : facteur de risque pour des troubles de l’anxiété
8/11/13
1 item of Media coverage
Press/Media: Research
Thesis
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A scavenger hunt towards a better understanding of the involvement of ghrelin receptor signaling in emotion regulation
Author: Pierre, A., De Bundel, D., Smolders, I., beckers, T., Mangelings, D., De Kock, J., Aerts, J., Singewald, N. & Dickson , S., 5 Feb 2020Supervisor: De Bundel, D. (Promotor), Smolders, I. (Co-promotor), beckers, T. (External person) (Co-promotor), Mangelings, D. (Jury), De Kock, J. (Jury), Aerts, J. (Jury), Singewald, N. (External person) (Jury) & Dickson , S. (External person) (Jury)
Student thesis: Doctoral Thesis
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Astrocytic endothelin-1 and cerebral hypoperfusion in multiple sclerosis
Author: Hostenbach, S., Kooijman, R., D'Haeseleer, M., De Keyser, J., De Bundel, D., Versijpt, J., Bissay, V., Van Eeckhaut, A., Hupperts, R. & Hellings, N., 16 Jul 2020Supervisor: Kooijman, R. (Promotor), D'Haeseleer, M. (Promotor), De Keyser, J. (Promotor), De Bundel, D. (Jury), Versijpt, J. (Jury), Van Eeckhaut, A. (Jury), Bissay, V. (Jury), Hupperts, R. (External person) (Jury) & Niels, H. (External person) (Jury)
Student thesis: Doctoral Thesis
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Characterization and reprogramming of umbilical cord-derived mesenchymal stromal cells towards the hepatic lineage
Author: Buyl, K., De Kock, J., Vanhaecke, T., Rogiers, V., De Bundel, D., Hernot, S., Vinken, M., Roskams, T., Najimi, M. & Castell, J., 28 Feb 2017Supervisor: De Kock, J. (Promotor), Vanhaecke, T. (Promotor), Rogiers, V. (Promotor), De Bundel, D. (Jury), Vinken, M. (Jury), Hernot, S. (Jury), Najimi, M. (External person) (Jury), Roskams, T. (External person) (Jury) & Castell, J. V. (External person) (Jury)
Student thesis: Doctoral Thesis
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Cognitive impairment in rodent model of Parkinson's disease
Author: Moons, G., 2016Supervisor: Deroost, N. (Promotor), Massie, A. (Promotor), Kerckhofs, E. (Promotor) & De Bundel, D. (Promotor)
Student thesis: Master's Thesis
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Development and biological evaluation of neuromedin U analogs as tools for functional elucidation: focus on stress-related disorders
Author: De Prins, A., Smolders, I., Ballet, S., Van Eeckhaut, A., De Bundel, D., Caveliers, V., Mangelings, D., Tourwe, D., Vinken, M., Simonin, F. & Van Calenbergh, S., 12 Dec 2018Supervisor: Smolders, I. (Promotor), Ballet, S. (Promotor), Van Eeckhaut, A. (Co-promotor), De Bundel, D. (Co-promotor), Caveliers, V. (Co-promotor), Mangelings, D. (Jury), Tourwe, D. (Jury), Vinken, M. (Jury), Simonin, F. (External person) (Jury) & Van Calenbergh, S. (External person) (Jury)
Student thesis: Doctoral Thesis