Projects per year
Personal profile
Expertise
Dimitri De Bundel is a lecturer to the Faculty of Medicine and Pharmacy. He graduated as a Pharmacist (summa cum laude, 2004) and obtained a PhD in Pharmaceutical Sciences (2009). During his PhD he gained expertise in in vivo neurochemistry methods and behavioural analysis. During a postdoctoral research stays in Karolinska Institutet (Sweden, 2009-2011) and Institut Génomique Fonctionelle (France, 2011-2014) he further developed his expertise in techniques for studying the neurobiological basis for cognitive function and mood regulation. He is now a principal investigator at VUB (since 2014) where he is investigating neurotransmitter and neuropeptide systems involved in memory and mood dysfunction. His core expertise lies in behavioural analysis and targeted pharmacological manipulation of brain transmitter systems in neurological and psychiatric disorders.
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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HERC56: Intravital imaging as tool to bridge the gap between macroscopic in vivo imaging and microscopic tissue analysis
Hernot, S., Staels, W., Hellemans, K., Smolders, I., Rooman, I., Devoogdt, N., Menu, E., De Bundel, D., Breckpot, K., De Leu, N., Movahedi, K., D'Huyvetter, M. & De Kock, J.
1/05/22 → 30/04/26
Project: Fundamental
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OZR3913: Cofinancing OZR FWO Hercules MZW - High-parametric single-cell protein profiling in intact tissues
Movahedi, K., van Grunsven, L., Rooman, I., Van Ginderachter, J., Smolders, I., Neyns, B., Vanhaecke, T., Laoui, D., Breckpot, K., De Veirman, K., Stijlemans, B., Van Schependom, J., Magez, S., Goyvaerts, C., De Kock, J., De Leu, N., Massie, A., Hellemans, K., Spits, C., De Bundel, D., De Trez, C., Hernot, S., Van Dooren, S., Aerts, J., Staels, W. & Tuyaerts, S.
25/02/22 → 25/02/26
Project: Fundamental
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FWOAL1042: Investigating the role of astrocytes and noradrenaline as critical regulators of neuronal circuit excitability.
1/01/22 → 31/12/25
Project: Fundamental
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ANI281: Role of neurogenesis in cognitive decline following stroke in co-morbid Alzheimer's dementia
De Bundel, D., Kooijman, R., Gens, R. & De Smet, A.
1/01/21 → 31/12/23
Project: Fundamental
Research output
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Ghrelin receptor agonist MK0677 and overnight fasting do not rescue deficient fear extinction in 129S1/SvImJ mice
Fritz, E. M., Pierre, A., De Bundel, D. & Singewald, N., 9 Feb 2023, In: Frontiers in psychiatry. 14, 1094948.Research output: Contribution to journal › Article › peer-review
Open Access -
Improving the LC-MS/MS analysis of neuromedin U-8 and neuromedin S by minimizing their adsorption behavior and optimizing UHPLC and MS parameters
Bongaerts, J., De Bundel, D., Smolders, I., Mangelings, D., Vander Heyden, Y. & Van Eeckhaut, A., 10 May 2023, In: Journal of Pharmaceutical and Biomedical Analysis. 228, 11 p., 115306.Research output: Contribution to journal › Article › peer-review
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Accelerated HF-rTMS Modifies SERT Availability in the Subgenual Anterior Cingulate Cortex: A Canine [11C] DASB Study on the Serotonergic System
Xu, Y., Kappen, M., Peremans, K., De Bundel, D., Van Eeckhaut, A., Van Laeken, N., De Vos, F., Dobbeleir, A., Saunders, J. H. & Baeken, C., 10 Mar 2022, In: Journal of Clinical Medicine. 11, 6, 12 p., 1531.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)42 Downloads (Pure) -
An Alzheimer’s disease mouse model, with increases in both soluble Aβ1-42 and tau, is more susceptible to induced seizures
Vande Vyver, M., Barker-Haliski, M., Aourz, N., Nagels, G., Bjerke, M., Engelborghs, S., De Bundel, D. & Smolders, I., 11 Jul 2022.Research output: Unpublished contribution to conference › Poster
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Assessment of gliotransmitter concentrations upon chemogenetic modulation of astroglia in mouse hippocampus
Nestor, L., Sahu, S., De Bundel, D., Van Eeckhaut, A. & Smolders, I., 9 May 2022, (Unpublished).Research output: Unpublished contribution to conference › Poster
Prizes
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Hugo d'Haenen Award
De Bundel, Dimitri (Recipient), 2 Oct 2015
Prize: Prize (including medals and awards)
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Les Grandes Avancées en Biologie-Santé du Pôle RABELAIS 2017
De Bundel, Dimitri (Recipient), 4 May 2017
Prize: Prize (including medals and awards)
Activities
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Psychedelica - de toekomst van mentaal welzijn?
Dimitri De Bundel (Invited speaker)
31 Mar 2022Activity: Talk or presentation › Talk at a public lecture/debate
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Psychedelica als medicijn
Dimitri De Bundel (Speaker)
27 Nov 2022Activity: Talk or presentation › Talk at a festival/exhibition
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Psychoneuroendocrinology (Journal)
Dimitri De Bundel (Peer reviewer)
2022 → …Activity: Publication peer-review and editorial work › Publication peer-review
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Ethical discussion on decisions made by the Ethical Committee for Animal Experimetnation.
Dimitri De Bundel (Speaker)
8 Dec 2022Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Nerdland Festival: BrainMan
Dimitri De Bundel (Invited speaker)
5 Jun 2022Activity: Talk or presentation › Talk at a festival/exhibition
Press/Media
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Trippen tegen trauma's: zijn psychedelica geneeskrachtig?
4/05/22
1 item of Media coverage
Press/Media: Research
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Kan nieuw onderzoek met algen het zicht van blinden verbeteren?
25/05/21
1 Media contribution
Press/Media: Expert Comment
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Une horloge biologique perturbée : facteur de risque pour des troubles de l’anxiété
8/11/13
1 item of Media coverage
Press/Media: Research
Thesis
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Ghrelin-monoamine interactions in anxiety disorders
Author: De Bundel, D. & Kisielewicz, D., 2015Student thesis: Master's Thesis
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Ghrelin Receptor Expression and the Effect of Systemic Administration of the Ghrelin Receptor Agonist MK0677 on Neuronal Activation in the Brain.
Author: Raventos Aymar, C. & De Bundel, D., 2018Supervisor: Pierre, A. (Promotor)
Student thesis: Master's Thesis
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Ghrelin receptor involvement in fear extinction
Author: De Bundel, D., De Heyn, S. & Smolders, I. J., 2015Student thesis: Master's Thesis
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Investigations towards the mechanisms of action of insulin-regulated aminopeptidase ligands in spatial memory and limbic seizures.
Author: De Bundel, D., Michotte, Y., Smolders, I. J., Siew Yeen, C., Albiston, A., Bruno, J., De Deyn, P., Gard, P., Vauquelin, G., Vander Heyden, Y., Vrijsen, R. & Vanhaecke, T., 2009Supervisor: Michotte, Y. (Promotor), Smolders, I. (Promotor), Vauquelin, G. (Jury), Vander Heyden, Y. (Jury), Vrijsen, R. (Jury), Vanhaecke, T. (Jury), Bruno, J. (External person) (Jury), De Deyn, P. (External person) (Jury), Gard, P. (External person) (Jury), Siew Yeen, C. (External person) (Co-promotor) & Albiston, A. (External person) (Co-promotor)
Student thesis: Doctoral Thesis
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NIR Imaging of HER2-positive breast cancer lesions using a site-specific fluorescently labeled nanobody
Author: Maldeghem, F., Hernot, S., Caveliers, V., De Bundel, D. & De Kock, J., 28 Jan 2016Supervisor: Hernot, S. (Promotor) & Caveliers, V. (Co-promotor)
Student thesis: Master's Thesis