Projects per year
Personal profile
Expertise
- organische synthese peptide synthese massaspectrometrie HPLC analyse
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Collaborations and top research areas from the last five years
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ADSP76: SPONSORING aan congres BPMG 2012 + Belgian Peptide Group Meeting 2014
15/01/12 → …
Project: Fundamental
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CONO411: Organisatie congres Belgian Peptide Group Meeting 2012 (BPGM)
10/10/12 → 31/12/12
Project: Fundamental
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CONI362: Inschrijvingen: 1)SIGMA - ALDRICH meeting 2011 2)BPMG 2012
1/09/11 → 31/12/13
Project: Fundamental
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FWOAL570: Discovery of novel opioid analgesics based on the chemical modification of the lead compound Dmt1-DALDA
1/04/10 → 31/03/13
Project: Fundamental
Research output
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Design, Synthesis, and In Vitro Characterization of ProteolyticallyStable Opioid-Neurotensin Hybrid Peptidomimetics
De Neve, J., Breault, É., Previti, S., Vangeloven, E., Loranger, B., Chartier, M., Brouillette, R., Lanoie, A., Holleran, B. J., Longpré, J-M., Gendron, L., Tourwe, D., Sarret, P. & Ballet, S., 19 Aug 2024, In: ACS pharmacology & translational science. 7, 9, p. 2784-2798 15 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design
Gimenez, L. E., Martin, C., Jing, Y., Hollanders, C., Hernandez, C., Wu, Y., Yao, D., Han, G. W., Dahir, N. S., Wu, L., Van Der Poorten, O., Lamouroux, A., Mannes, M., Zhao, S., Tourwe, D., Stevens, R. C., Cone, R. D. & Ballet, S., 22 Feb 2024, In: Journal of Medicinal Chemistry. 67, 4, p. 2690-2711 22 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Opening the amino acid toolbox for peptide-based NTS2-selective ligands as promising lead compounds for pain management
Previti, S., Desgagné, M., Tourwé, D., Cavelier, F., Sarret, P. & Ballet, S., 11 Jan 2023, In: Journal of Peptide Science. 29, 6, p. n/a 17 p., e3471.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Comprehensive overview of biased pharmacology at the opioid receptors: biased ligands and bias factors
De Neve, J., Barlow, T. M. A., Tourwe, D., Bihel, F., Simonin, F. & Ballet, S., Jun 2021, In: RSC Medicinal Chemistry. 12, 6, p. 828-870 43 p.Research output: Contribution to journal › Article › peer-review
23 Citations (Scopus) -
Structure-Based Design of Melanocortin 4 Receptor Ligands Based on the SHU-9119-hMC4R Cocrystal Structure †
Martin, C., Gimenez, L. E., Williams, S. Y., Jing, Y., Wu, Y., Hollanders, C., Van Der Poorten, O., Gonzalez, S., Van Holsbeeck, K., Previti, S., Lamouroux, A., Zhao, S., Tourwé, D., Stevens, R. C., Cone, R. D. & Ballet, S., 14 Jan 2021, In: Journal of medicinal chemistry. 64, 1, p. 357-369 13 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus)
Prizes
Activities
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Scientific Committee 'Belgian Organic Synthesis Symposium' (BOSS)
Dirk Tourwe (Participant)
2013 → …Activity: Participating in or organising an event › Participation in workshop, seminar
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15th Sigma-Aldrich Organic Synthesis Meeting
Dirk Tourwe (Organiser)
15 Dec 2011 → 16 Dec 2011Activity: Participating in or organising an event › Participation in conference
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University of Warsaw (External organisation)
Dirk Tourwe (Member)
1 Jan 2004 → 31 Dec 2005Activity: Membership › Membership of external research organisation
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Montreal Clinical Research Institute (External organisation)
Dirk Tourwe (Member)
7 Mar 2001 → …Activity: Membership › Membership of external research organisation
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Bioorganic & Medicinal Chemistry Letters (External organisation)
Dirk Tourwe (Member)
2001 → 2008Activity: Membership › Membership of peer-review panel or committee
Thesis
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Trifluoromethylated proline surrogates as part of "Pro-Pro" turn-inducing templates for the design of beta-hairpin mimetics
Author: Van Holsbeeck, K., Tourwé, D. & Madder, A., Jun 2018Supervisor: Ballet, S. (Promotor)
Student thesis: Master's Thesis