Projects per year
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
Projects
- 1 Finished
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FWOSB55: A roadmap to the safe introduction of hESC in the clinic: the case of genetic mosaicism in hESC-derived retinal cells
Couvreu De Deckersberg, E., Spits, C. & Sermon, K.
1/01/19 → 31/12/22
Project: Fundamental
Research output
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Loss of 18q Alters TGFβ Signalling Affecting Anteroposterior Neuroectodermal Fate in Human Embryonic Stem Cells
lei, Y., Duong, C. M., Krivec, N., Janssens, C., Regin, M., Huyghebaert, A., Deckersberg, E. C. D., Sermon, K., Delbany, D. A. & Spits, C., 5 Feb 2025, In: Cell Proliferation. 12 p., e13813.Research output: Contribution to journal › Article › peer-review
Open Access -
The interplay between mitochondrial DNA genotypes, female infertility, ovarian response and mutagenesis in oocytes
Van Der Kelen, A., Li Piani, L., Mertens, J., Regin, M., Couvreu De Deckersberg, E., Van De Velde, H., Sermon, K., Tournaye, H., Verpoest, W., Hes, F. J., Blockeel, C. & Spits, C., 2025, In: Human reproduction open. 2025, 1, 13 p., hoae074.Research output: Contribution to journal › Article › peer-review
Open Access -
Children born after assisted reproduction more commonly carry a mitochondrial genotype associating with low birthweight
Spits, C., Mertens, J., Belva, F., van Montfoort, A. PA., Regin, M., Zambelli, F., Seneca, S., Couvreu De Deckersberg, E., Bonduelle, M-L., Tournaye, H., Stouffs, K., Barbé, K., Smeets, B., Van De Velde, H., Sermon, K. & Blockeel, C., 9 Feb 2024, In: Nature Communications. 15, 1, 16 p., 1232 .Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)7 Downloads (Pure) -
Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos
Regin, M., Lei, Y., Couvreu De Deckersberg, E., Janssens, C., Huyghebaert, A., Guns, Y., Verdyck, P., Verheyen, G., Van de Velde, H., Sermon, K. & Spits, C., 9 Dec 2024, In: eLife. 12, 24 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity
Krivec, N., Couvreu De Deckersberg, E., Lei, Y., Al Delbany, D., Regin, M., Verhulst, S., van Grunsven, L. A., Sermon, K. & Spits, C., 21 Nov 2024, In: Cell Death and Disease. 15, 14 p., 852.Research output: Contribution to journal › Article › peer-review
Open Access
Activities
- 6 Talk or presentation at a conference
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Mitochondrial DNA mosaicism in early human development
Joke Mertens (Speaker), Marius Regin (Contributor), Neelke De Munck (Contributor), Edouard Couvreu De Deckersberg (Contributor), Christophe Blockeel (Contributor), Herman Tournaye (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor) & Claudia Spits (Contributor)
17 Sep 2021Activity: Talk or presentation › Talk or presentation at a conference
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Aneuploidy induces proteotoxic stress and autophagy-mediated apoptosis in human preimplantation embryos
Marius Regin (Speaker), Edouard Couvreu De Deckersberg (Contributor), Yves Guns (Contributor), Pieter Verdyck (Contributor), Greta Verheyen (Contributor), Hilde Van De Velde (Contributor), Claudia Spits (Contributor) & Karen Sermon (Contributor)
1 Jul 2021Activity: Talk or presentation › Talk or presentation at a conference
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Maternally inherited differences in mitochondrial DNA genotype between ART and spontaneously conceived individuals associate with low birthweight
Joke Mertens (Speaker), Florence Belva (Contributor), Aafke PA van Montfoort (Contributor), Filippo Zambelli (Contributor), Sara Seneca (Contributor), Edouard Couvreu De Deckersberg (Contributor), Mary-Louise Bonduelle (Contributor), Herman Tournaye (Contributor), Katrien Stouffs (Contributor), Kurt Barbé (Contributor), Hubert J M Smeets (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor), Christophe Blockeel (Contributor) & Claudia Spits (Contributor)
30 Jun 2021Activity: Talk or presentation › Talk or presentation at a conference
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Aneuploidy induces proteotoxic stress and autophagy-mediated apoptosis in human preimplantation embryos
Marius Regin (Speaker), Yingnan Lei (Contributor), Edouard Couvreu De Deckersberg (Contributor), Yves Guns (Contributor), Pieter Verdyck (Contributor), Greta Verheyen (Contributor), Hilde Van De Velde (Contributor), Claudia Spits (Contributor) & Karen Sermon (Contributor)
26 Nov 2021 → 27 Nov 2021Activity: Talk or presentation › Talk or presentation at a conference
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Differences in the landscape of mitochondrial DNA variants between ART and spontaneously conceived individuals links to maternal infertility and low birth weight
Joke Mertens (Speaker), Filippo Zambelli (Contributor), Florence Belva (Contributor), Aafke PA van Montfoort (Contributor), Edouard Couvreu De Deckersberg (Contributor), Mary-Louise Bonduelle (Contributor), Katrien Stouffs (Contributor), Sara Seneca (Contributor), Hilde Van De Velde (Contributor), Christophe Blockeel (Contributor), Karen Sermon (Contributor) & Claudia Spits (Contributor)
5 Jul 2020 → 8 Jul 2020Activity: Talk or presentation › Talk or presentation at a conference
Thesis
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Impact of recurrent chromosome abnormalities on the transcriptome of human embryonic stem cells.
Author: Couvreu De Deckersberg, E. & Spits, C., 2018Supervisor: Spits, C. (Promotor)
Student thesis: Master's Thesis