Projects per year
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Dive into the research topics where Ella Martin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Projects
- 1 Finished
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Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity
Martin, E., Giakoumakis, D., Paesmans, J., Bisi, N., Drozdzecki, A., Audenaert, D., Haustraete, J., Verstreken, P., Galicia, C., Ballet, S. & Versées, W., 18 May 2025, (Accepted/In press) In: ACS Pharmacology and Translational Science. 11 p.Research output: Contribution to journal › Article › peer-review
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Cryo-EM structures of the MnmE-MnmG complex reveal large conformational changes and provide new insights into the mechanism of tRNA modification
Maes, L., Martin, E., Bickel, D., Claeys, S., Vranken, W., Fislage, M., Galicia, C. & Versées, W., 30 Nov 2024Research output: Other contribution
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Structural and functional insights in Synaptojanin1 and its implication in disease
Martin, E., Paesmans, J., Berghmans, M., Galicia Diaz Santana, C. & Versées, W., 13 May 2024, (Unpublished).Research output: Unpublished contribution to conference › Poster
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EndophilinA-dependent coupling between activity-induced calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation
Bademosi, A. T., Decet, M., Kuenen, S., Calatayud, C., Swerts, J., Gallego, S. F., Schoovaerts, N., Karamanou, S., Louros, N., Martin, E., Sibarita, J-B., Vints, K., Gounko, N. V., Meunier, F. A., Economou, A., Versées, W., Rousseau, F., Schymkowitz, J., Soukup, S-F. & Verstreken, P., 3 May 2023, In: Neuron. 111, 9, p. 1402-1422.e13 21 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)124 Downloads (Pure) -
Nanobodies as versatile tools to unravel the mechanism and modulate the activity of key proteins in Parkinson’s disease
Galicia Diaz Santana, C., Dal Maso, T., Martin, E. & Versées, W., 2023.Research output: Unpublished contribution to conference › Poster
Datasets
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Crystal structure of the 5-phosphatase domain of Synaptojanin1 in complex with a nanobody
Paesmans, J. (Creator), Versées, W. (Supervisor), Galicia Diaz Santana, C. (Creator) & Martin, E. (Creator), Protein Data Bank in Europe, 30 Dec 2020
DOI: 10.2210/pdb7A0V/pdb
Dataset
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Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody.
Paesmans, J. (Creator), Versées, W. (Supervisor), Galicia Diaz Santana, C. (Creator) & Martin, E. (Creator), Protein Data Bank in Europe, 30 Dec 2020
DOI: 10.2210/pdb7A17/pdb
Dataset
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Synaptojanin1: from structure elucidation towards drug design
Ella Martin (Speaker) & Wim Versées (Contributor)
17 May 2023Activity: Talk or presentation › Talk or presentation at a conference
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Cryo-EM Workshop
Ella Martin (Participant)
12 Dec 2019 → 13 Dec 2019Activity: Participating in or organising an event › Participation in workshop, seminar
Thesis
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Cloning, expression and characterization of the Sac1 domain of the synaptic protein Synaptojanin1
Author: Boyana, D. S., Martin, E. & Versées, W., 2021Student thesis: Master's Thesis
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Effect of disease-associated mutations on the function of the human synaptic protein Synaptojanin1
Author: Berghmans, M., Martin, E., Versées, W., Remaut, H. & Vanderheyden, P., 2020Student thesis: Master's Thesis