Projects per year
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
Projects
- 1 Finished
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FWOSB78: Structural and functional characterization of the dual activity lipid phosphatase Synaptojanin 1 and its validation as a new drug target for intractable epilepsy
Versées, W. (Administrative Promotor) & Martin, E. (Mandate)
1/11/19 → 31/10/23
Project: Fundamental
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Cryo-EM structures of the MnmE-MnmG complex reveal large conformational changes and provide new insights into the mechanism of tRNA modification
Maes, L., Mares-Mejía, I., Martin, E., Bickel, D., Claeys, S., Vranken, W., Fislage, M., Galicia, C. & Versées, W., 9 Sept 2025, In: Nucleic Acids Research. 53, 16, 17 p., gkaf824.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)7 Downloads (Pure) -
Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity
Martin, E., Giakoumakis, D., Paesmans, J., Bisi, N., Drozdzecki, A., Audenaert, D., Haustraete, J., Verstreken, P., Galicia, C., Ballet, S. & Versées, W., 12 Sept 2025, In: ACS Pharmacology and Translational Science. 8, 9, p. 2996-3006 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)4 Downloads (Pure) -
Synaptojanin1: From Structural Insights to Therapeutic Targeting
Martin, E., Paesmans, J., Berghmans, M., Giakoumakis, D., Galicia Diaz Santana, C. & Versées, W., 2025.Research output: Unpublished contribution to conference › Poster
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The presynaptic phosphoinositide phosphatase Synaptojanin1: From structural insights to therapeutic targeting
Martin, E., 2025, Crazy Copy Center Productions. 183 p.Research output: Thesis › PhD Thesis
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Cryo-EM structures of the MnmE-MnmG complex reveal large conformational changes and provide new insights into the mechanism of tRNA modification
Maes, L., Martin, E., Bickel, D., Claeys, S., Vranken, W., Fislage, M., Galicia, C. & Versées, W., 30 Nov 2024Research output: Other contribution
Datasets
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Discovery and characterization of a selective inhibitor of Synaptojanin1 5-phosphatase activity
Martin, E. (Creator), Giakoumakis, D. (Creator), Paesmans, J. (Creator), Bisi, N. (Creator), Drozdzecki, A. (Creator), Audenaert, D. (Creator), Haustraete, J. (Creator), Verstreken, P. (Creator), Galicia Diaz Santana, C. (Creator), Ballet, S. (Creator) & Versées, W. (Creator), Zenodo, 12 Sept 2025
Dataset
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Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody.
Paesmans, J. (Creator), Versées, W. (Supervisor), Galicia Diaz Santana, C. (Creator) & Martin, E. (Creator), Protein Data Bank in Europe, 30 Dec 2020
DOI: 10.2210/pdb7A17/pdb
Dataset
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Crystal structure of the 5-phosphatase domain of Synaptojanin1 in complex with a nanobody
Paesmans, J. (Creator), Versées, W. (Supervisor), Galicia Diaz Santana, C. (Creator) & Martin, E. (Creator), Protein Data Bank in Europe, 30 Dec 2020
DOI: 10.2210/pdb7A0V/pdb
Dataset
Activities
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Synaptojanin1: From Structural Insights to Therapeutic Targeting
Martin, E. (Speaker) & Versées, W. (Contributor)
14 Nov 2025Activity: Talk or presentation › Talk or presentation at a conference
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PhD Defence Ella Martin (Event)
Martin, E. (Presenter), Versées, W. (Supervisor), Laoui, D. (Chair), Hennecke, U. (Jury), Vorobieva, A. A. (Jury), Greggio, E. (Jury) & Ismail, S. (Jury)
29 Sept 2025Activity: Membership › Member of PhD committee
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Synaptojanin1: from structure elucidation towards drug design
Martin, E. (Speaker) & Versées, W. (Contributor)
17 May 2023Activity: Talk or presentation › Talk or presentation at a conference
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Cryo-EM Workshop
Martin, E. (Participant)
12 Dec 2019 → 13 Dec 2019Activity: Participating in or organising an event › Participation in workshop, seminar