Projects per year
Personal profile
Expertise
Prof Dr Ellen Goossens graduated in Biomedical Sciences at the Vrije Universiteit Brussel in 2000. She is trained in male fertility preservation under supervision of Prof. Dr. Herman Tournaye at the laboratory Biology of the Testis of the Vrije Universiteit Brussel, where she obtained her doctoral degree in 2006. She undertook postdoctoral training in the same lab and became lab coordinator in 2012. Currently, she is chairman of the research group Biology of the Testis and focusses on cryopreservation, transplantation and in vitro differentiation of spermatogonial stem cells.
She has published more than 80 papers in (inter)national journals and contributed to 7 book chapters. She has been invited to speak at many national and international conferences. In 2011, she was awarded the prize of the Royal Belgian Academy for Medicine for her work on prevention of infertility after chemo- or radiotherapy.
Ellen Goossens is affiliated to the faculty of Medicine and Pharmacy of the Vrije Universiteit Brussel. She is exchange coordinator for bachelor and master students Biomedical Sciences. She is basic science officer of the ESHRE Special Interest Group Andrology and associate editor for two peer-reviewed journals in the field of reproduction.
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IWTSBO13: SEGa - The Science and Ethics of stem cell-derived Gametes
1/02/16 → 31/01/20
Project: Applied
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EU470: GROWSPERM: Development of in vitro and in vivo strategies to avoid and cure male infertility.
1/05/14 → 30/04/18
Project: Fundamental
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HERC66: 3D-CELLMAP: Unveiling complex cellular interactions in tissues through 3D super-resolution protein multiplex imaging
Movahedi, K., Rooman, I., Sermon, K., De Bundel, D., Fioravanti, A., Staels, W., Magez, S., Breckpot, K., De Kock, J., Laoui, D., Goyvaerts, C., Smolders, I., Van Ginderachter, J., Marcelino Rodrigues, R., De Leu, N., van Grunsven, L., Hernot, S., Peeters, E., Vanhaecke, T., De Veirman, K., Ruytinx, J., Van Schependom, J., Kortekaas, I. & Goossens, E.
1/05/24 → 31/05/28
Project: Fundamental
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Fertility preservation in boys: recent developments and new insights †
Goossens, E., Jahnukainen, K., Mitchell, RT., Pelt, AMM. V., Pennings, G., Rives, N., Poels, J., Wyns, C., Lane, S., Rodriguez-Wallberg, KA., Rives, A., Valli-Pulaski, H., Steimer, S., Kliesch, S., Braye, A., Andres, MM., Medrano, J., Ramos, L., Kristensen, SG., Andersen, CY., & 4 others , 6 Jun 2020, In: Human reproduction open. 2020, 3, hoaa016.Research output: Contribution to journal › Article › peer-review
Open Access137 Citations (Scopus) -
Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women
Delgouffe, E., Madureira Silva, S., Chalmel, F., Cools, W., Raets, C., Tilleman, K., T'Sjoen, G., Baert, Y. & Goossens, E., 7 Jan 2025, In: eLife. 13, 25 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Downloads (Pure) -
A 20-year overview of fertility preservation in boys: new insights gained through a comprehensive international survey
Duffin, K., Neuhaus, N., Andersen, C. Y., Barraud-Lange, V., Braye, A., Eguizabal, C., Feraille, A., Ginsberg, J. P., Gook, D., Goossens, E., Jahnukainen, K., Jayasinghe, Y., Keros, V., Kliesch, S., Lane, S., Mulder, C., Orwig, K. E., Ans, M. M. V. P., Poirot, C., Rimmer, M., & 8 others , 16 Feb 2024, In: Human reproduction open. 2024, 2, 11 p., hoae010.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)5 Downloads (Pure) -
A new clinically relevant classification of seminiferous tubules in Klinefelter Syndrome patients based on the karyotype of the Sertoli cells.
Gül, S., Vloeberghs, V., Gies, I. & Goossens, E., 3 Jul 2024.Research output: Unpublished contribution to conference › Poster
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Expression of CTLA-4, PD-1, and PD-L1 proteins by testicular cells
Ntemou, E., Delgouffe, E. & Goossens, E., 2024, (Unpublished).Research output: Unpublished contribution to conference › Poster
Datasets
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miRNA in semen and urine of NOA patients
Goossens, E. (Project Manager) & Willems, M. (Creator), Gene Expression Omnibus (GEO), 2023
DOI: GSE224511
Dataset
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20-year overview of fertility preservation in boys
Goossens, E. (Creator), Duffin, K. (Data Manager), Neuhaus, N. (Data Manager), Andersen, C. (Data Collector), Barraud-Lange, V. (Data Collector), Braye, A. (Data Collector), Eguizabal, C. (Data Collector), Feraille, A. (Data Collector), Ginsberg, J. (Creator), Gook, D. (Data Collector), Jahnukainen, K. (Data Collector), Jaysinghe, Y. (Data Collector), Keros, V. (Data Collector), Kliesch, S. (Data Collector), Lane, S. (Data Collector), Mulder, C. (Data Collector), Orwig, K. E. (Data Collector), Van Pelt, A. (Data Collector), Poirot, C. (Data Collector), Rimmer, M. (Data Collector), Rives, N. (Data Collector), Sadri-Ardekani, H. (Data Collector), Safrai, M. (Data Collector), Schlatt, S. (Data Collector), Stukenborg, J. (Data Collector), Van De Wetering, M. (Data Collector), Wyns, C. (Data Collector) & Mitchell, R. (Project Manager), Zenodo, 13 Dec 2024
Dataset
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Testicular mosaicism in non-mosaic postpubertal Klinefelter patients with focal spermatogenesis and in non-mosaic prepubertal Klinefelter boys
Gül, S. (Researcher), Vloeberghs, V. (Creator), Gies, I. (Creator) & Goossens, E. (Creator), Zenodo, 23 Jan 2025
Dataset
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Effect of childhood cancer and hematological disorders on spermatogonial quantity at diagnosis
Goossens, E. (Creator) & Ntemou, E. (Creator), VUB Institutional Data Repository, 6 Dec 2024
Dataset
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Patient follow-up (≥18 years)
Goossens, E. (Creator), Braye, A. (Creator) & Delgouffe, E. (Creator), VUB Institutional Data Repository, 2024
Dataset
Prizes
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Prijs Dr. Luc Broeckaert an Mevr Annie Depreeuw
Goossens, Ellen (Recipient), 19 Nov 2011
Prize: Prize (including medals and awards)
Activities
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Fertility preservation: Translation into the clinic
Ellen Goossens (Keynote speaker)
8 Dec 2020Activity: Talk or presentation › Talk or presentation at a conference
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De Nederlandse en Belgische visie op fertiliteitspreservatie: van spermatogoniale stamcel tot testisweefsel
Ellen Goossens (Speaker)
21 May 2025Activity: Talk or presentation › Talk or presentation at a conference
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University of Amsterdam (External organisation)
Ellen Goossens (Jury)
25 Jun 2025Activity: Membership › Member of PhD committee
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Faculty of Medicine and Pharmacy (Organisational unit)
Ellen Goossens (Chair)
26 Jun 2025Activity: Membership › Member of PhD committee
Press/Media
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interview over eerste testiculaire weefseltransplantatie bij de mens
9/01/25
1 Media contribution
Press/Media: Other
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Wereldprimeur in UZ Brussel: ingevroren teelbalweefsel na 16 jaar succesvol teruggeplaatst
9/01/25
1 Media contribution
Press/Media: Other
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Wereldprimeur in UZ Brussel: ingevroren teelbalweefsel na 16 jaar succesvol teruggeplaatst
9/01/25
1 Media contribution
Press/Media: Other
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Wereldprimeur in UZ Brussel: ingevroren teelbalweefsel na 16 jaar succesvol teruggeplaatst
9/01/25
1 Media contribution
Press/Media: Other
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VUB zet stap om vruchtbaarheid bij mannen te herstellen na kankerbehandeling
9/01/25
1 Media contribution
Press/Media: Other
Thesis
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Architectural comparison of murine- and pig-derived testicular organoids: creating mini testicles for in-vitro spermatogenesis studies
Author: Normann, C., Goossens, E. & Baert, Y., 2024Student thesis: Master's Thesis
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Characterization of germ cells in testicular tissue from transgenders
Author: Adams, C. P., Goossens, E. & Van Saen, D., 2019Student thesis: Master's Thesis
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Cultuuroptimalisatie en transplantatie van testiculaire stamcellen in een muismodel
Author: Goossens, E. & Tournaye, H., 2000Supervisor: Tournaye, H. (Promotor)
Student thesis: Master's Thesis
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Mechanisms of testicular fibrosis in Klinefelter syndrome
Author: Seßenhausen, P., Willems, M., Goossens, E. & Van Saen, D., 15 Jun 2021Student thesis: Master's Thesis
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Protein expression during testicular development
Author: Oriza Calvo, E., Van Saen, D. & Goossens, E., Sept 2015Student thesis: Master's Thesis