Projects per year
Personal profile
Expertise
Prof Dr Ellen Goossens graduated in Biomedical Sciences at the Vrije Universiteit Brussel in 2000. She is trained in male fertility preservation under supervision of Prof. Dr. Herman Tournaye at the laboratory Biology of the Testis of the Vrije Universiteit Brussel, where she obtained her doctoral degree in 2006. She undertook postdoctoral training in the same lab and became lab coordinator in 2012. Currently, she is chairman of the research group Biology of the Testis and focusses on cryopreservation, transplantation and in vitro differentiation of spermatogonial stem cells.
She has published more than 120 papers in (inter)national journals and contributed to 8 book chapters. She has been invited to speak at many national and international conferences. In 2011, she was awarded the prize of the Royal Belgian Academy for Medicine for her work on prevention of infertility after chemo- or radiotherapy.
Ellen Goossens is affiliated to the faculty of Medicine and Pharmacy of the Vrije Universiteit Brussel. She is vice-president of the educational board Biomedical Sciences. She is co-founder of Orchid-net, member of Andronet and associate editor for two peer-reviewed journals in the field of reproduction.
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- 1 Similar Profiles
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FWOAL1023: Fertility preservation in boys treated for cancer: evaluating the impact of harvesting testicular tissue at young age on the later pubertal development and fertility (prospective study)
Goossens, E. (Administrative Promotor), Gies, I. (CoI (Co-Promotor)) & Tournaye, H. (CoI (Co-Promotor))
1/01/21 → 31/12/22
Project: Fundamental
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IWTSBO13: SEGa - The Science and Ethics of stem cell-derived Gametes
Sermon, K. (Collaborator) & Goossens, E. (Administrative Promotor)
1/02/16 → 31/01/20
Project: Applied
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EU470: GROWSPERM: Development of in vitro and in vivo strategies to avoid and cure male infertility.
Goossens, E. (Administrative Promotor)
1/05/14 → 30/04/18
Project: Fundamental
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FWOAL1141: Establishing refined inclusion criteria for immature testicular tissue banking based on patient followup and assessing the (need for and) efficiency of fertility restoration by autologous grafting
Goossens, E. (Administrative Promotor), Gies, I. (CoI (Co-Promotor)) & Tournaye, H. (CoI (Co-Promotor))
1/01/25 → 31/12/28
Project: Fundamental
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HERC66: 3D-CELLMAP: Unveiling complex cellular interactions in tissues through 3D super-resolution protein multiplex imaging
Movahedi, K. (Administrative Promotor), Rooman, I. (CoI (Co-Promotor)), Sermon, K. (CoI (Co-Promotor)), De Bundel, D. (CoI (Co-Promotor)), Fioravanti, A. (CoI (Co-Promotor)), Staels, W. (CoI (Co-Promotor)), Magez, S. (CoI (Co-Promotor)), Breckpot, K. (CoI (Co-Promotor)), De Kock, J. (CoI (Co-Promotor)), Laoui, D. (CoI (Co-Promotor)), Goyvaerts, C. (CoI (Co-Promotor)), Smolders, I. (CoI (Co-Promotor)), Van Ginderachter, J. (CoI (Co-Promotor)), Marcelino Rodrigues, R. (CoI (Co-Promotor)), De Leu, N. (CoI (Co-Promotor)), van Grunsven, L. (CoI (Co-Promotor)), Hernot, S. (CoI (Co-Promotor)), Peeters, E. (CoI (Co-Promotor)), Vanhaecke, T. (CoI (Co-Promotor)), De Veirman, K. (CoI (Co-Promotor)), Ruytinx, J. (CoI (Co-Promotor)), Van Schependom, J. (CoI (Co-Promotor)), Kortekaas, I. (CoI (Co-Promotor)) & Goossens, E. (CoI (Co-Promotor))
1/05/24 → 31/05/28
Project: Fundamental
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Fertility preservation in boys: recent developments and new insights †
Goossens, E., Jahnukainen, K., Mitchell, R., Pelt, A. V., Pennings, G., Rives, N., Poels, J., Wyns, C., Lane, S., Rodriguez-Wallberg, K., Rives, A., Valli-Pulaski, H., Steimer, S., Kliesch, S., Braye, A., Andres, M., Medrano, J., Ramos, L., Kristensen, S. & Andersen, C. & 4 others, , 6 Jun 2020, In: Human reproduction open. 2020, 3, hoaa016.Research output: Contribution to journal › Article › peer-review
Open Access155 Citations (Scopus) -
A new human in vitro model of cytotypic and testosterone-producing organoids derived from testicular tissue of transgender women
Silva, S. M., Chalmel, F., Errico, A., Papageorgiou, K., Richer, G., Peng, E. C. S., Rolland, A., Tilleman, K., T'Sjoen, G., Dando, I., Vanhaecke, T., Goossens, E. & Baert, Y., 20 Aug 2025, In: Human reproduction open. 3, 49 p., hoaf043.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
ESHRE good practice recommendations on fertility preservation involving testicular tissue cryopreservation in children receiving gonadotoxic therapies
Mitchell, R. T., Eguizabal, C., Goossens, E., Grynberg, M., Jahnukainen, K., Clef, N. L., Mulder, C. L., Neuhaus, N., Rimmer, M. P., Stukenborg, J.-B., Wetering, M. D. V. D., Pelt, A. M. M. V. & Wyns, C., 1 Aug 2025, In: Human Reproduction. 40, 8, p. 1391-1431 41 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
In vitro models for gonadal and placental toxicity: A review and industry survey
Silva, S. M., Cruchten, S. V., Goethem, F. V., Vanhaecke, T., Goossens, E. & Baert, Y., 2025, In: NAM Journal. 1, p. 1-18 18 p., 100052.Research output: Contribution to journal › Article › peer-review
Open Access -
Is the time right for transplanting immature testicular tissue or cells to restore male fertility? Expert perspectives on clinical implementation of autotransplantation of cryopreserved testicular tissue or cells for fertility restoration
Safrai, M., Goossens, E., Mitchell, R. T., Orwig, K. E., Mulder, C. L., van Pelt, A. M. M., Gook, D. A., Feraille, A., Delgouffe, E., Ginsberg, J. P., Stukenborg, J-B., Duffin, K., Jahnukainen, K., Andersen, C. Y., van de Wetering, M. D., Rimmer, M. P., Barraud-Lange, V., Neuhaus, N., Lane, S., Sadri-Ardekani, H., & 2 others, Sept 2025, In: Best Practice & Research Clinical Obstetrics and Gynaecology. 102, 9 p., 102638.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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miRNA in semen and urine of NOA patients
Goossens, E. (Project Manager) & Willems, M. (Creator), Gene Expression Omnibus (GEO), 2023
DOI: GSE224511
Dataset
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20-year overview of fertility preservation in boys
Goossens, E. (Creator), Duffin, K. (Data Manager), Neuhaus, N. (Data Manager), Andersen, C. (Data Collector), Barraud-Lange, V. (Data Collector), Braye, A. (Data Collector), Eguizabal, C. (Data Collector), Feraille, A. (Data Collector), Ginsberg, J. (Creator), Gook, D. (Data Collector), Jahnukainen, K. (Data Collector), Jaysinghe, Y. (Data Collector), Keros, V. (Data Collector), Kliesch, S. (Data Collector), Lane, S. (Data Collector), Mulder, C. (Data Collector), Orwig, K. E. (Data Collector), Van Pelt, A. (Data Collector), Poirot, C. (Data Collector), Rimmer, M. (Data Collector), Rives, N. (Data Collector), Sadri-Ardekani, H. (Data Collector), Safrai, M. (Data Collector), Schlatt, S. (Data Collector), Stukenborg, J.-B. (Data Collector), Van De Wetering, M. (Data Collector), Wyns, C. (Data Collector) & Mitchell, R. (Project Manager), Zenodo, 13 Dec 2024
Dataset
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Testicular mosaicism in non-mosaic postpubertal Klinefelter patients with focal spermatogenesis and in non-mosaic prepubertal Klinefelter boys
Gül, S. (Researcher), Vloeberghs, V. (Creator), Gies, I. (Creator) & Goossens, E. (Creator), Zenodo, 23 Jan 2025
Dataset
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Intratesticular xenografting of Klinefelter pre-pubertal testis tissue as potential model to study testicular fibrosis
Goossens, E. (Project Leader), Willems, M. (Researcher), Seßenhausen, P. (Researcher), Gies, I. (Supervisor), Vloeberghs, V. (Project Member), Tournaye, H. (Supervisor) & Van Saen, D. (Project Leader), Zenodo, 5 May 2022
Dataset
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Prospective patient follow-up (<18 years)
Goossens, E. (Creator) & Delgouffe, E. (Creator), VUB Institutional Data Repository, 3 Oct 2025
Dataset
Prizes
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Prijs Dr. Luc Broeckaert an Mevr Annie Depreeuw
Goossens, Ellen (Recipient), 19 Nov 2011
Prize: Prize (including medals and awards)
Activities
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Fertility preservation: Translation into the clinic
Goossens, E. (Keynote speaker)
8 Dec 2020Activity: Talk or presentation › Talk or presentation at a conference
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University of Amsterdam (External organisation)
Goossens, E. (Jury)
25 Jun 2025Activity: Membership › Member of PhD committee
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23rd European Testis Workshop
Goossens, E. (Chair)
17 Apr 2025Activity: Participating in or organising an event › Participation in conference
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Rachel McKernan
Goossens, E. (Host)
26 Aug 2025 → 5 Sept 2025Activity: Hosting a visitor › Hosting a non-academic visitor
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Faculty of Medicine and Pharmacy (Organisational unit)
Goossens, E. (Jury)
2025Activity: Membership › Member of PhD committee
Press/Media
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Protecting boys’ fertility: Emily Delgouffe at VUB
Emily Delgouffe & Ellen Goossens
1/09/25
1 item of Media coverage
Press/Media: Other
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Hoe kunnen jongens met kanker later nog kinderen krijgen?
9/01/25
1 Media contribution
Press/Media: Other
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Wereldprimeur in UZ Brussel: ingevroren teelbalweefsel na 16 jaar succesvol teruggeplaatst bij man (26)
9/01/25
1 Media contribution
Press/Media: Other
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interview over eerste testiculaire weefseltransplantatie bij de mens
9/01/25
1 Media contribution
Press/Media: Other
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Wereldprimeur in UZ Brussel: ingevroren teelbalweefsel na 16 jaar succesvol teruggeplaatst
9/01/25
1 Media contribution
Press/Media: Other
Thesis
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Architectural comparison of murine- and pig-derived testicular organoids: creating mini testicles for in-vitro spermatogenesis studies
Author: Normann, C., Goossens, E. & Baert, Y., 2024Student thesis: Master's Thesis
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Characterization of germ cells in testicular tissue from transgenders
Author: Adams, C. P., Goossens, E. & Van Saen, D., 2019Student thesis: Master's Thesis
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Cultuuroptimalisatie en transplantatie van testiculaire stamcellen in een muismodel
Author: Goossens, E. & Tournaye, H., 2000Supervisor: Tournaye, H. (Promotor)
Student thesis: Master's Thesis
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Mechanisms of testicular fibrosis in Klinefelter syndrome
Author: Seßenhausen, P., Willems, M., Goossens, E. & Van Saen, D., 15 Jun 2021Student thesis: Master's Thesis
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Protein expression during testicular development
Author: Oriza Calvo, E., Van Saen, D. & Goossens, E., Sept 2015Student thesis: Master's Thesis