Research output per year
Research output per year
Personal profile
Expertise
After I obtained my Master degree at Vrije Universiteit Brussels, faculty Medicine & Pharmacy, I was selected as a PhD candidate at the lab of Molecular Oncology under supervision of Prof. Dr. Ilse Rooman. Here I finished my master thesis, which was focused on pancreatic acinar dedifferentiation. Currently, I perform a PhD study aiming to establish patient-derived organoids as a reliable and efficient model to study fundamental biology of pancreatic cancer. Extensive tissue characterization and sequencing methods clarify whether these models are suitable to ensure patient identity.
My PhD project is sponsored by Innoser NV - a biomedical CRO service - located both in Belgium and The Netherlands. I am working on their PDXO project aiming to develop an innovative platform to test oncological drugs in a preclinical setting.
Education/Academic qualification
Pancreatic cancer, Masters degree, Vrije Universiteit Brussel
External positions
Employee, Innoser NV
1 Sep 2019 → …Fingerprint
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Research output
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Multicellular Modelling of Difficult-To-Treat Gastrointestinal Cancers: Current Possibilities and Challenges
Michiels, E., Rooman, I., Hawinkels, L. JAC., Hakuno, S., Messaoudi, N. & Slingerland, M., 15 Mar 2022, In : International Journal of Molecular Sciences. 23, 6, 15 p., 3147.Research output: Contribution to journal › Scientific review
Open AccessFile18 Downloads (Pure) -
MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions
Backx, E., Wauters, E., Baldan, J., Van Bulck, M., Michiels, E., Heremans, Y., De Paep, D. L., Kurokawa, M., Goyama, S., Bouwens, L., Jacquemin, P., Houbracken, I. & Rooman, I., Sep 2021, In : Cell Death and Differentiation. 28, 9, p. 2601-2615 15 p.Research output: Contribution to journal › Article
Open AccessFile7 Citations (Scopus)29 Downloads (Pure) -
Setting up a PDXO platform for pancreatic cancer with spatial omics characterization
Michiels, E., 5 Oct 2021, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization
Michiels, E., Heremans, Y. & Rooman, I., 29 Jun 2021, (In preparation).Research output: Unpublished contribution to conference › Poster
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Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization
Michiels, E., Rooman, I. & Heremans, Y., 27 May 2021, (In preparation).Research output: Unpublished contribution to conference › Poster
Activities
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Charity Quiz PhD United
Ellis Michiels (Chair)3 Mar 2022Activity: Participating in or organising an event › Participating in or organizing a school event
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Setting up a PDXO platform for pancreatic cancer with spatial omics characterization
Ellis Michiels (Speaker)9 Oct 2021Activity: Talk or presentation › Talk or presentation at a conference
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ORC Seminar
Ellis Michiels (Speaker)6 May 2021Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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PhD United Online Quiz
Ellis Michiels (Chair)25 Feb 2021Activity: Participating in or organising an event › Participating in or organizing a school event
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Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization
Ellis Michiels (Speaker), Ilse Rooman (Contributor), Yves Heremans (Contributor)6 May 2021Activity: Talk or presentation › Talk or presentation at a workshop/seminar
Press / Media
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Setting up a PDXO platform of pancreatic cancer with spatial-omics characterization
27/09/21
1 Media contribution
Press/Media: Public Engagement Activities
Thesis
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MECOM as a transcriptional regulator of pancreatic acinar dedifferentiation
Author: Michiels, E., 30 Jun 2019Supervisor: Rooman, I. (Promotor)
Student thesis: Master's Thesis