Projects per year
Personal profile
Expertise
I am a PhD student currently employed at the Laboratory for Molecular and Cellular Therapy (LMCT, VUB). I have obtained a Master degree in Biomedical Sciences at the Vrije Universiteit Brussel. My PhD project is a joint project between the LMCT and ICMI research groups in which I will focus on the development of an in vivo nanoCAR-T cell therapy.
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Dive into the research topics where Fien Meeus is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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ANI395: CARGO: advancing chimeric antigen receptor T cell therapy using nanobodydisplaying lentiviral vectors
1/11/24 → 31/10/25
Project: Fundamental
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IOFPOC42: IOF PoC “MOTIF: MOdification of T cells In situ for altered Functionality”
Devoogdt, N., Breckpot, K., Meeus, F., De Groof, T. & De Vlaeminck, Y.
1/01/21 → 31/12/22
Project: Applied
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FWOSB101: CARGO: advancing chimeric antigen receptor T cell therapy using nanobody-displaying lentiviral vectors
1/11/20 → 31/10/24
Project: Fundamental
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Anti-Idiotypic VHHs and VHH-CAR-T Cells to Tackle Multiple Myeloma: Different Applications Call for Different Antigen-Binding Moieties
Hanssens, H., Meeus, F., Gesquiere, E. L., Puttemans, J., Vlaeminck, Y. D., Veirman, K. D., Breckpot, K. & Devoogdt, N., 22 May 2024, In: International Journal of Molecular Sciences. 25, 11, 16 p., 5634.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Scrutiny of chimeric antigen receptor activation by the extracellular domain: experience with single domain antibodies targeting multiple myeloma cells highlights the need for case-by-case optimization
Hanssens, H., Meeus, F., De Vlaeminck, Y., Lecocq, Q., Puttemans, J., Debie, P., De Groof, T. W. M., Goyvaerts, C., De Veirman, K., Breckpot, K. & Devoogdt, N., 2024, In: Frontiers in Immunology. 15, 15 p., 1389018.Research output: Contribution to journal › Article › peer-review
Open Access -
Development and evaluation of nanobody tracers for noninvasive nuclear imaging of the immune-checkpoint TIGIT
Zeven, K., De Groof, T. W. M., Ceuppens, H., Awad, R. M., Ertveldt, T., de Mey, W., Meeus, F., Raes, G., Breckpot, K. & Devoogdt, N., 20 Sep 2023, In: Frontiers in Immunology. 14, 1, 16 p., 1268900.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)26 Downloads (Pure) -
In vitro modelling of local gene therapy with IL-15/IL-15Rα and a PD-L1 antagonist in melanoma reveals an interplay between NK cells and CD4+ T cells
Awad, R. M., De Vlaeminck, Y., Meeus, F., Ertveldt, T., Zeven, K., Ceuppens, H., Goyvaerts, C., Verdonck, M., Salguero, G., Raes, G., Devoogdt, N. & Breckpot, K., Dec 2023, In: Scientific reports. 13, 1, p. 1-13 13 p., 18995.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)8 Downloads (Pure) -
Emerging applications of nanobodies in cancer therapy
Awad, R. M., Meeus, F., Ceuppens, H., Ertveldt, T., Hanssens, H., Lecocq, Q., Mateusiak, L., Zeven, K., Valenta, H., De Groof, T. W. M., De Vlaeminck, Y., Krasniqi, A., De Veirman, K., Goyvaerts, C., D'Huyvetter, M., Hernot, S., Devoogdt, N. & Breckpot, K., 2022, In: International review of cell and molecular biology. 369, p. 143-199 57 p.Research output: Contribution to journal › Scientific review › peer-review
Open AccessFile14 Citations (Scopus)456 Downloads (Pure)
Activities
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Development of an in vitro hot tumor model for immunotherapeutic drug screening
Robin Maximilian Awad (Presenter), Fien Meeus (Contributor), Yannick De Vlaeminck (Contributor), Nick Devoogdt (Contributor) & Karine Breckpot (Contributor)
21 Sep 2022Activity: Talk or presentation › Talk or presentation at a conference
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2021-80
Nick Devoogdt (Supervisor), Timo De Groof (Contributor), Fien Meeus (Contributor), Karine Breckpot (Contributor) & Yannick De Vlaeminck (Contributor)
2021 → …Activity: Other
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Human relevant models for drug research and development
Fien Meeus (Speaker), Robin Maximilian Awad (Contributor), Nick Devoogdt (Contributor), Sandra Tuyaerts (Contributor), Cleo Goyvaerts (Contributor), Yannick De Vlaeminck (Contributor), Bart Neyns (Contributor) & Karine Breckpot (Contributor)
8 Oct 2021Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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FWO-SB fellowship: CARGO: advancing chimeric antigen receptor T cell therapy using nanobody-displaying lentiviral vectors.
Fien Meeus (Participant) & Fien Meeus (Contributor)
1 Nov 2020 → 31 Oct 2024Activity: Other › Written proposal
Press/Media
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Betaalbare kankerimmunotherapie
Karine Breckpot, Nick Devoogdt, Yannick De Vlaeminck & Fien Meeus
8/02/22
1 item of Media coverage
Press/Media: Research
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VUB-onderzoek naar gedeeltelijk falen immuuntherapie
Karine Breckpot, Fien Meeus & Yannick De Vlaeminck
3/02/22
1 Media contribution
Press/Media: Research
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VUB-onderzoekers en start-up Esobiotec streven naar betaalbare kankerimmunotherapie
Karine Breckpot, Nick Devoogdt, Yannick De Vlaeminck & Fien Meeus
31/01/22
1 Media contribution
Press/Media: Research
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VUB-onderzoekers en start-up Esobiotec willen kankerimmunotherapie betaalbaarder maken
Karine Breckpot, Nick Devoogdt, Fien Meeus & Yannick De Vlaeminck
31/01/22
1 item of Media coverage
Press/Media: Research
Thesis
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Assessment of antigen-binding domain parameters important for adequate CAR-T-cell activation: evaluating different SLAMF7-targeting nanobodies.
Author: Meeus, F., Hanssens, H., De Veirman, K. & Devoogdt, N., 19 Jun 2020Supervisor: Hanssens, H. (Advisor)
Student thesis: Master's Thesis