Projects per year
Personal profile
Expertise
As associate chair of neurology in the UZ Brussel, my clinical focus is diagnosis, treatment and rehabilitation in multiple sclerosis (MS). Cognition is an important though often underrated aspect of MS, and this has caused my research focus to grow into the modelling of cognition in MS and other neurodegenerative disorders. I feel that the combination of my clinical neuroscience background, together with my formal training as a computer science engineer, sets the stage for the development of more informed and more performant models of cognition. To this end, I have gathered a multidisciplinary team consisting of engineers, psychologists and fellow neurologists. Together we form the cognition and modelling group, part of the centre for neurosciences (C4N) of the Vrije Universiteit Brussel (VUB), where I am associate professor of cellular neurophysiology and coordinator of the neural engineering track in the master in biomedical engineering program. Our cognition and modelling group works in close collaboration with the Oxford centre for Human Brain Activity, where I hold academic visitor status since 2012, with the magnetoencephalography unit at the Université Libre de Bruxelles, and with industrial partners such as the spinoff neuroimaging company icometrix nv. We also have a long standing collaboration with the BIODEM lab at the University of Antwerp, resulting in publications on motor activity recordings and neurophysiological markers of cognition in dementia.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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FWOAL1150: Federated causal inference to link structural brain damage to cognitive impairment in multiple sclerosis
1/01/25 → 31/12/28
Project: Fundamental
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FWOTM1241: Network learning for cognition in multiple sclerosis
1/10/24 → 30/09/29
Project: Fundamental
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FWOAL1118: Meta-dynamic modelling of functional brain networks (MEMOBRAIN)
Nagels, G., Nowe, A. & Loeckx, J.
1/01/24 → 31/12/27
Project: Fundamental
Research output
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A New Smartphone-Based Cognitive Screening Battery for Multiple Sclerosis (icognition): Validation Study
Denissen, S., Van Laethem, D., Baijot, J., Costers, L., Descamps, A., Van Remoortel, A., Van Merhaegen-Wieleman, A., D'hooghe, M., D'Haeseleer, M., Smeets, D., Sima, D. M., Van Schependom, J. & Nagels, G., 20 Jan 2025, In: Journal of Medical Internet Research. 27, 16 p., e53503.Research output: Contribution to journal › Article › peer-review
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Virtual reality for multiple sclerosis rehabilitation
De Keersmaecker, E., Guida, S., Denissen, S., Dewolf, L., Nagels, G., Jansen, B., Beckwée, D. & Swinnen, E., 7 Jan 2025, In: Cochrane Database of Systematic Reviews. 1, 1, 125 p., CD013834.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Brain age as a biomarker for pathological versus healthy ageing - a REMEMBER study
Wittens, M. M. J., Denissen, S., Sima, D. M., Fransen, E., Niemantsverdriet, E., Bastin, C., Benoit, F., Bergmans, B., Bier, J-C., de Deyn, P. P., Deryck, O., Hanseeuw, B., Ivanoiu, A., Picard, G., Ribbens, A., Salmon, E., Segers, K., Sieben, A., Struyfs, H., Thiery, E. & 7 others, , Dec 2024, In: Alzheimer's Research & Therapy. 16, 1, 18 p., 128.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Cardiorespiratory Fitness and Sleep, but not Physical Activity, are Associated with Functional Connectivity in Older Adults
Wing, D., Roelands, B., Wetherell, J. L., Nichols, J. F., Meeusen, R., Godino, J. G., Shimony, J. S., Snyder, A. Z., Nishino, T., Nicol, G. E., Nagels, G., Eyler, L. T. & Lenze, E. J., 2024, In: Sports medicine - open. 10, 1, 16 p., 113.Research output: Contribution to journal › Article › peer-review
Open Access -
Clinical effectiveness of coronavirus disease 2019 vaccination in patients with multiple sclerosis stratified by disease-modifying treatment.
De, T. M., Van, R. A., Van, S. J., Faille, LD., D'hooghe, MB., Peeters, G., Nagels, G. & D'Haeseleer, M., 19 Apr 2024, In: European Journal of Neurology. 31, 7, 8 p., e16300.Research output: Contribution to journal › Article › peer-review
Open Access
Activities
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Artificiële intelligentie zal de gezondheidszorg binnen tien jaar verbeteren
Jeroen Van Schependom (Speaker) & Guy Nagels (Speaker)
25 Mar 2023Activity: Talk or presentation › Talk at an external academic organisation
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artificial intelligence opportunities
Guy Nagels (Speaker)
15 Sep 2023Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Human-Prosthetic Interaction: Brain & Technology After Lower Limb Loss
Elke Lathouwers (Contributor), Kevin De Pauw (Supervisor), Guy Nagels (Supervisor) & Johan De Mey (Supervisor)
1 Mar 2022Activity: Other › Written proposal
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LOK vergadering neurologie 2021/1
Alex Michotte (Organiser), Veronique Bissay (Participant), Fenne Vandervorst (Participant), Guy Nagels (Participant), Ilse Peeters (Participant), Jan Versijpt (Participant), Miguel D'Haeseleer (Participant), Sebastiaan Engelborghs (Participant), Sylvie De Raedt (Participant), Ayla Pauwels (Participant), Wietse Wiels (Participant) & Anja Flamez (Participant)
25 Mar 2021Activity: Participating in or organising an event › Participation in workshop, seminar
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FWO aspirant fellowship: Cognitive-motor telerehabilitation in multiple sclerosis
Delphine Van Laethem (Contributor), Guy Nagels (Supervisor), Jeroen Van Schependom (Participant) & Frederik Van de Steen (Participant)
2021 → 2023Activity: Other › Written proposal
Thesis
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A comparison of the by tDCS induced electrical field distribution between healthy controls and MS patients
Author: Thienpont, M., Van Schependom, J., Stiens, J. & Nagels, G., 2023Student thesis: Master's Thesis
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Applying a microbiome-age model to a subfertile population: An AI-based approach
Author: Derua, J., Demuyser, T., Nagels, G. & Denissen, S., 2024Student thesis: Master's Thesis
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Assessing working memory in people with multiple sclerosis: Comparing different scoring methods for the backward digit span
Author: Wöhler, F., Van Schependom, J., Nagels, G. & Van Laethem, D., 2023Student thesis: Master's Thesis
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Characterising neurophysiological processes behind Information Processing Speed in Multiple Sclerosis
Author: Burta, O. D., Van Schependom, J., Nagels, G. & Denissen, S., Jul 2024Supervisor: Akbarian, F. (Advisor)
Student thesis: Master's Thesis
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Cognition derived from neuroimaging data in multiple sclerosis using deep learning
Author: Wiels, T., Nagels, G. & Van Schependom, J., 2024Student thesis: Master's Thesis