As associate chair of neurology in the UZ Brussel, my clinical focus is diagnosis, treatment and rehabilitation in multiple sclerosis (MS). Cognition is an important though often underrated aspect of MS, and this has caused my research focus to grow into the modelling of cognition in MS and other neurodegenerative disorders. I feel that the combination of my clinical neuroscience background, together with my formal training as a computer science engineer, sets the stage for the development of more informed and more performant models of cognition. To this end, I have gathered a multidisciplinary team consisting of engineers, psychologists and fellow neurologists. Together we form the cognition and modelling group, part of the centre for neurosciences (C4N) of the Vrije Universiteit Brussel (VUB), where I am associate professor of cellular neurophysiology and coordinator of the neural engineering track in the master in biomedical engineering program. Our cognition and modelling group works in close collaboration with the Oxford centre for Human Brain Activity, where I hold academic visitor status since 2012, with the magnetoencephalography unit at the Université Libre de Bruxelles, and with industrial partners such as the spinoff neuroimaging company icometrix nv. We also have a long standing collaboration with the BIODEM lab at the University of Antwerp, resulting in publications on motor activity recordings and neurophysiological markers of cognition in dementia.