Projects per year
Personal profile
Expertise
(i) glucose sensing system in alpha- and beta cells, (ii) transcription factors that support the phenotype of beta cells and control reprogramming of non-beta cells of the endocrine pancreas, (iii) development of experimental models to study beta cell neogenesis by differentiation from stem/progenitor cells and by proliferation of preexisting and newly formed beta cells.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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FWOTM1142: Deciphering the involvement of iron metabolism in beta cell differentiation, maturation, and function.
Staels, W., De Leu, N., Heimberg, H. & Van Mulders, A.
1/11/22 → 31/10/26
Project: Fundamental
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OZR3783: Bilateral cooperation within the framework of a joint doctoral project: benchfee for joint PhD VUB - KU Leuven, BOLCKMANS Lenz
9/06/21 → 8/06/25
Project: Fundamental
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OZR3588: Financiering FWO hercules: ERA platform: Extended RNA Analysis platform - version 2.0
Rooman, I., Bouwens, L., Heimberg, H., Neyns, B., Vranken, W., Vanhaecke, T., Massie, A., van Grunsven, L., De Bruyne, E., De Bundel, D., Forsyth, R., Breckpot, K., Van Dooren, S., De Kock, J., Njemini, R. & Laoui, D.
1/05/20 → 30/04/24
Project: Fundamental
Research output
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Correction: Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas (Cell Stem Cell (2021) 28(11) (2000–2008.e4), (S1934590921003404), (10.1016/j.stem.2021.08.003))
Gribben, C., Lambert, C., Messal, H. A., Hubber, E-L., Rackham, C., Evans, I., Heimberg, H., Jones, P., Sancho, R. & Behrens, A., 6 Apr 2023, In: Cell Stem Cell. 30, 4, p. 498-499 2 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease
Martens, S., Coolens, K., Van Bulck, M., Arsenijevic, T., Casamitjana, J., Fernandez Ruiz, A., El Kaoutari, A., Martinez de Villareal, J., Madhloum, H., Esni, F., Heremans, Y., Leuckx, G., Heimberg, H., Bouwens, L., Jacquemin, P., De Paep, D. L., In't Veld, P., D'Haene, N., Bouchart, C., Dusetti, N. & 6 others, , 1 Oct 2022, In: Gut. 71, 10, p. 2030-2042 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)22 Downloads (Pure) -
Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas
Gribben, C., Lambert, C., Messal, H. A., Hubber, E-L., Rackham, C., Evans, I., Heimberg, H., Jones, P., Sancho, R. & Behrens, A., 4 Nov 2021, In: Cell Stem Cell. 28, 11, p. 2000-2008.e4 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)26 Downloads (Pure) -
Towards a Functional Cure for Diabetes Using Stem Cell-Derived Beta Cells: Are We There Yet?
Bourgeois, S., Sawatani, T., Van Mulders, A., De Leu, N., Heremans, Y., Heimberg, H., Cnop, M. & Staels, W., 19 Jan 2021, In: Cells. 10, 1, 24 p., 191.Research output: Contribution to journal › Article › peer-review
Open Access26 Citations (Scopus) -
Retraction Note: Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice
Baeyens, L., Lemper, M., Leuckx, G., De Groef, S., Bonfanti, P., Stangé, G., Shemer, R., Nord, C., Scheel, D. W., Pan, F. C., Ahlgren, U., Gu, G., Stoffers, D. A., Dor, Y., Ferrer, J., Gradwohl, G., Wright, C. V. E., Van de Casteele, M., German, M. S., Bouwens, L. & 1 others, , Mar 2020, In: Nature Biotechnology. 38, 3, p. 374-374 1 p., 374.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)
Prizes
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Belgian Endocrine Society Annual Lecture Award
Heimberg, Henry (Recipient), 2002
Prize: Prize (including medals and awards)
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EASD/Eli Lilly Research Fellowship in Diabetes and Metabolism
Heimberg, Henry (Recipient), 2001
Prize: Prize (including medals and awards)
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Fulbright-Hays Award for Research
Heimberg, Henry (Recipient), 1994
Prize: Prize (including medals and awards)
Activities
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Diabetes genezen met stamcellen
Henry Heimberg (Participant)
Apr 2010Activity: Participating in or organising an event › Participating in or organizing a public lecture/debate
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Stamcellen als therapie voor diabetes
Henry Heimberg (Participant)
Sep 2010Activity: Participating in or organising an event › Participating in or organizing a public lecture/debate
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Invited chair and organizer of the scientific program of the 15th EASD Oxford Hagedorn Workshop
Henry Heimberg (Organiser)
Aug 2010Activity: Participating in or organising an event › Participation in workshop, seminar
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Unknown (External organisation)
Henry Heimberg (Member)
1 Sep 2009 → 2011Activity: Membership › Membership of external research organisation
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Beta cell neogenesis
Henry Heimberg (Participant)
Mar 2008Activity: Participating in or organising an event › Participating in or organizing a public lecture/debate
Thesis
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Endothelial cells in beta cell generation and protection
Author: Salinno, C., Heimberg, H., De Leu, N. & De Groef, S., 2015Supervisor: De Leu, N. (Advisor)
Student thesis: Master's Thesis
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Generation of ligand activated sentinels embedded in Rosa26 to study intercellular signaling in ES cells and mice”
Author: Gustavsen, C. R., Serup, P., Nielsen, J. H. & Heimberg, H., Aug 2014Student thesis: Doctoral Thesis
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Genetische tracering van pancreatische transdifferentiatie
Author: Houbracken, I., Heimberg, H. & Bouwens, L., 28 Jun 2005Supervisor: Bouwens, L. (Promotor) & Heimberg, H. (External person) (Co-promotor)
Student thesis: Master's Thesis
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Human Pancreatic Acinar Cell Plasticity.
Author: Baldan, J., Arnes, L., Jacquemin, P., Spits, C., Heimberg, H., Sermon, K. & Bouwens, L., 28 Sep 2020Supervisor: Arne, L. (External person) (Jury), Jacquemin, P. (External person) (Jury), Spits, C. (Jury), Heimberg, H. (External person) (Jury), Segers, K. (Jury) & Bouwens, L. (Promotor)
Student thesis: Doctoral Thesis
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Identification des gènes cibles du facteur de transcription Neurogenin 3 et étude de leur fonction au cours du développement pancréatique
Author: Soyer, J., Mellitzer, G. & Heimberg, H., Oct 2009Student thesis: Doctoral Thesis