Projects per year
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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A challenging road towards creating a human phenylalanine ammonia lyase enzyme to treat phenylketonuria
Nulmans, I., 2025, 236 p.Research output: Thesis › PhD Thesis
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A robust bacterial high-throughput screening assay to identify pharmacological chaperones targeting human homogentisate 1,2-dioxygenase missense variants in alkaptonuria
Lequeue, S., Allach, H., Nulmans, I., Desmet, L., Salvi, N. S., Rombaut, M., Neuckermans, J., Schwaneberg, U., Vanhaecke, T. & Kock, J. D., Oct 2025, In: European Journal of Pharmacology. 1005, 13 p., 178048.Research output: Contribution to journal › Article › peer-review
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Current state of the treatment landscape of phenylketonuria
Nulmans, I., Lequeue, S., Desmet, L., Neuckermans, J. & De Kock, J., 5 Jun 2025, In: Orphanet Journal of Rare Diseases. 20, 1, p. 281 16 p., 281.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Development of a human cell-based test system to evaluate the catalytic activity of ammonia lyase enzymes for therapeutic use in aminoacidopathies
Nulmans, I., Salvi, N. & De Kock, J., 5 Mar 2025, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Phenylketonuria: A guide through the complex maze of its neurological pathophysiology providing a new perspective on treatment strategies
Nulmans, I., Lequeue, S., Desmet, L., Del'Haye, G., Salvi, N., Rombaut, M., Neuckermans, J. & De Kock, J., Oct 2025, In: Biomedicine & Pharmacotherapy. 191, 11 p., 118522.Research output: Contribution to journal › Article › peer-review
Open Access
Prizes
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PiKachU: Development of human phenylalanine ammonia lyase enzymes to treat phenylketonuria using directed protein evolution
Nulmans, Ine (Recipient), 8 Oct 2021
Prize: Fellowship awarded competitively
Activities
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Faculty of Medicine and Pharmacy (Organisational unit)
Ine Nulmans (Member)
Jun 2024 → Oct 2025Activity: Membership › Work on academic committees and working groups
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Development of a robust high-throughput screenings assay for the evaluation of bacterial tyrosine ammonia lyases in the context of tyrosinemia type 1 and alkaptonuria
Ine Nulmans (Invited speaker)
27 Jul 2023 → 28 Jul 2023Activity: Talk or presentation › Talk or presentation at a conference
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Development of a robust high-throughput screenings assay for the evaluation of bacterial tyrosine ammonia lyases in the context of tyrosine-inherited metabolic disorders
Ine Nulmans (Speaker)
27 Aug 2023 → 1 Sept 2023Activity: Talk or presentation › Talk or presentation at a conference
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Society for The Study of Inborn Errors of Metabolism Annual Symposium 2023
Ine Nulmans (Participant)
27 Aug 2023 → 1 Sept 2023Activity: Participating in or organising an event › Participation in conference
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The 13th International Conference on AKU
Ine Nulmans (Participant)
27 Jul 2023 → 28 Jul 2023Activity: Participating in or organising an event › Participation in conference
Thesis
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The development of a high-throughput screening assay to evaluate the catalytic activity and substrate specificity of human histidine ammonia lyase variants
Author: Neuckermans, J., Nulmans, I. & De Kock, J., 2021Student thesis: Master's Thesis
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The development of a high-througput screening assay to evaluate the catalytic activity and substrate specificity of human histidine ammonia lyase variants
Author: Nulmans, I. & De Kock, J., 2021Supervisor: De Kock, J. (Promotor)
Student thesis: Master's Thesis