Projects per year
Personal profile
Expertise
My work is focused on the development of biosensors for addressing questions regarding glucose metabolism. This is achieved by a series of biomolecular techniques. Different steps, from development and structure solving to applications in cells, are covered.
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Dive into the research topics where Israel Pérez Chávez is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Projects
- 1 Finished
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OZR3624: OZR back-up mandate: Evolutionary designed protein-based sensors to probe for glycolytic flux
Pérez Chávez, I. (Mandate) & Messens, J. (Administrative Promotor)
1/11/20 → 31/10/21
Project: Fundamental
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Genome editing of TXNIP in human pluripotent stem cells for the generation of hepatocyte-like cells and insulin-producing islet-like aggregates
Traini, L., Negueruela, J., Elvira, B., St-Pierre-Wijckmans, W., Vandenbempt, V., Buss, C. E., Li, A., Pérez-Chávez, I., Ribeiro-Costa, F., Nunes, M., Messens, J., Ezeriņa, D., Hay, D. C., Bansal, M. & Gurzov, E. N., Dec 2025, In: Stem Cell Research & Therapy. 16, 1, 18 p., 225.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Protocol for real-time glycolytic monitoring in mammalian cells using confocal microscopy and HYlight, a biosensor for fructose 1,6-bisphosphate
Pérez-Chávez, I., Baeyens, N., Ezeriņa, D., Gurzov, E. N. & Messens, J., 20 Jun 2025, In: STAR Protocols. 6, 2, p. 1-15 15 p., 103792.Research output: Contribution to journal › Article › peer-review
Open Access -
Single-cell imaging of liver metabolic dynamics using fluorescent biosensors
Pérez-Chávez, I., Gilglioni, E. H., Ezeriņa, D., Messens, J. & Gurzov, E. N., 10 Nov 2025, In: Trends in Endocrinology and Metabolism. 17 p.Research output: Contribution to journal › Article › peer-review
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PTPRK regulates glycolysis and de novo lipogenesis to promote hepatocyte metabolic reprogramming in obesity
Gilglioni, E. H., Li, A., St-Pierre-Wijckmans, W., Shen, T.-K., Pérez-Chávez, I., Hovhannisyan, G., Lisjak, M., Negueruela, J., Vandenbempt, V., Bauzá-Martinez, J., Herranz, J. M., Ezeriņa, D., Demine, S., Feng, Z., Vignane, T., Otero Sanchez, L., Lambertucci, F., Prašnická, A., Devière, J. & Hay, D. C. & 8 others, , 4 Nov 2024, In: Nature communications. 15, 1, 22 p., 9522.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)4 Downloads (Pure) -
Tracking fructose 1,6-bisphosphate dynamics in liver cancer cells using a fluorescent biosensor
Pérez-Chávez, I., Koberstein, J. N., Malo Pueyo, J., Gilglioni, E. H., Vertommen, D., Baeyens, N., Ezeriņa, D., Gurzov, E. N. & Messens, J., 20 Dec 2024, In: iScience. 27, 12, 22 p., 111336.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)9 Downloads (Pure)
Prizes
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File
Activities
- 1 Talk or presentation at a conference
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L-Lactate Biosensor : Unravelling Cancer Metabolic Secrets
Pérez Chávez, I. (Speaker)
1 Dec 2019Activity: Talk or presentation › Talk or presentation at a conference
Thesis
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Generating a Lactate Biosensor: a new tool to analyse cancer cell metabolism in vivo
Pérez Chávez, I. ((PhD) Student), Ezeriņa, D. (Promotor) & Messens, J. (Promotor), Messens, J. (Promotor) & Ezerina, D. (Promotor), 2020Student thesis: Master's Thesis