Research output per year
Research output per year
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Dive into the research topics where Jan Brughmans is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Depleting IL1R2+ Tumor-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Anti-PD1 Immunotherapy
Arnouk, S. M., Kancheva, D., Van Damme, H., Courtoy, G. E., Mora Barthelmess, R., Van Craenenbroeck, J., Lebegge, E., Elkrim, Y., Assaf, N., Heremans, Y., Murgaski, A., De Groof, T. W. M., Clappaert, E., Debraekeleer, A., Brughmans, J., Blancke, G., Kiss, M., Forsyth, R., Waelput, W. & Boon, L. & 9 others, , 1 Dec 2025, In: Cancer Research. 85, 23, p. 4681-4700 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)92 Downloads (Pure) -
Epigenomic preconditioning of peripheral monocytes determines their transcriptional response to the tumor microenvironment
Kiss, M., Halasz, L., Hadadi, E., Berger, W. K., Tzerpos, P., Poliska, S., Kancheva, D., Gabriel, A., Mora Barthelmess, R., Debraekeleer, A., Brughmans, J., Elkrim, Y., Martens, L., Saeys, Y., Daniel, B., Czimmerer, Z., Laoui, D., Nagy, L. & Van Ginderachter, J. A., 23 Jul 2025, In: Genome Medicine. 17, 1, p. 1-17 17 p., 82.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)6 Downloads (Pure) -
CD40 agonist treatment potentiates the anti-tumor effect of tumor-derived cDC therapy in cDC therapy resistant tumor models
Deschoemaeker, S., Murgaski, A., Clappaert, E., Kancheva, D., Gordún Peiró, A., Debraekeleer, A., Brughmans, J., Elkrim, Y., Bardet, P., Hamouda, A. E. I. & Laoui, D., 2024, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Intratumoral delivery of lipid nanoparticle-formulated mRNA encoding IL-21, IL-7, and 4-1BBL induces systemic anti-tumor immunity
Hamouda, A. E. I., Filtjens, J., Brabants, E., Kancheva, D., Debraekeleer, A., Brughmans, J., Jacobs, L., Bardet, P. M. R., Knetemann, E., Lefesvre, P., Allonsius, L., Gontsarik, M., Varela, I., Crabbé, M., Clappaert, E. J., Cappellesso, F., Caro, A. A., Peiró, A. G., Fredericq, L. & Hadadi, E. & 9 others, , 6 Dec 2024, In: Nature communications. 15, 1, 20 p., 10635.Research output: Contribution to journal › Article › peer-review
Open AccessFile92 Citations (Scopus)7 Downloads (Pure) -
Tumor-derived dendritic cells in human and murine ovarian carcinomas exhibit high heterogeneity
Gordún Peiró, A., Caro, A. A., Kancheva, D., Debraekeleer, A., Brughmans, J., Baert, T., Kempeneers, J., Coosemans, A. & Laoui, D., 17 May 2024.Research output: Unpublished contribution to conference › Poster
Datasets
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Intratumoral delivery of lipid nanoparticle-formulated mRNA encoding IL-21, IL-7, and 4-1BBL induces systemic anti-tumor immunity
Laoui, D. (Creator), Hamouda, A. E. I. (Creator), Filtjens, J. (Creator), Brabants, E. (Creator), Kancheva, D. (Creator), Debraekeleer, A. (Creator), Brughmans, J. (Creator), Jacobs, L. (Creator), Bardet, P. (Creator), Knetemann, E. (Creator), Lefesvre, P. (Creator), Allonsius, L. (Creator), Gontsarik, M. (Creator), Varela, I. (Creator), Crabbé, M. (Creator), Clappaert, E. (Creator), Cappellesso, F. (Creator), Caro, A. A. (Creator), Gordún Peiró, A. (Creator), Fredericq, L. (Creator), Hadadi, E. (Creator), Senti, M. E. (Creator), Schiffelers, R. (Creator), van Grunsven, L. (Creator), Nana, F. A. (Creator), De Geest, B. (Creator), Deschoemaeker, S. (Creator), De Koker, S. (Creator) & Lambolez, F. (Creator), NCBI Gene Expression Omnibus, 12 Nov 2024
Dataset
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Intratumoral administration of mRNA-based formulation for solid tumor immunotherapy
Hamouda, A. E. I. (Speaker), Filtjens, J. (Contributor), Brabants, E. (Contributor), Kancheva, D. (Contributor), Debraekeleer, A. (Contributor), Brughmans, J. (Contributor), Jacobs, L. (Contributor), Bardet, P. (Contributor), Varela, I. (Contributor), Crabbé, M. (Contributor), Clappaert, E. (Contributor), Allonsius, L. (Contributor), Hadadi, E. (Contributor), De Koker, S. (Contributor), De Geest, B. (Contributor), Deschoemaeker, S. (Contributor), Lambolez, F. (Contributor) & Laoui, D. (Contributor)
30 Jan 2025Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Intratumoral delivery of lipid nanoparticle-formulated mRNA encoding IL-21, IL-7, and 4-1BBL induces anti-tumor immunity
Hamouda, A. E. I. (Speaker), Filtjens, J. (Contributor), Brabants, E. (Contributor), Kancheva, D. (Contributor), Debraekeleer, A. (Contributor), Brughmans, J. (Contributor), Jacobs, L. (Contributor), Bardet, P. (Contributor), Varela, I. (Contributor), Crabbé, M. (Contributor), Clappaert, E. (Contributor), Allonsius, L. (Contributor), Hadadi, E. (Contributor), Senti, M. E. (Contributor), Schiffelers, R. (Contributor), De Koker, S. (Contributor), De Geest, B. (Contributor), Deschoemaeker, S. (Contributor), Lambolez, F. (Contributor) & Laoui, D. (Contributor)
25 Sept 2025Activity: Talk or presentation › Talk or presentation at a conference
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Intratumoral delivery of lipid nanoparticle-formulated mRNA encoding IL-21, IL-7, and 4-1BBL induces anti-tumor immunity
Hamouda, A. E. I. (Speaker), Filtjens, J. (Contributor), Brabants, E. (Contributor), Kancheva, D. (Contributor), Debraekeleer, A. (Contributor), Brughmans, J. (Contributor), Jacobs, L. (Contributor), Bardet, P. (Contributor), Varela, I. (Contributor), Crabbé, M. (Contributor), Clappaert, E. (Contributor), Allonsius, L. (Contributor), Hadadi, E. (Contributor), Senti, M. E. (Contributor), Schiffelers, R. (Contributor), De Koker, S. (Contributor), De Geest, B. (Contributor), Deschoemaeker, S. (Contributor), Lambolez, F. (Contributor) & Laoui, D. (Contributor)
25 Nov 2024Activity: Talk or presentation › Talk or presentation at a conference
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Intratumoral administration of mRNA-based formulation for solid tumor immunotherapy
Hamouda, A. E. I. (Speaker), Filtjens, J. (Contributor), Brabants, E. (Contributor), Kancheva, D. (Contributor), Debraekeleer, A. (Contributor), Brughmans, J. (Contributor), Jacobs, L. (Contributor), Bardet, P. (Contributor), Varela, I. (Contributor), Crabbé, M. (Contributor), Clappaert, E. (Contributor), Allonsius, L. (Contributor), Hadadi, E. (Contributor), De Koker, S. (Contributor), De Geest, B. (Contributor), Deschoemaeker, S. (Contributor), Lambolez, F. (Contributor) & Laoui, D. (Contributor)
14 Mar 2024Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Immune 'Space' exploration: Multiomics profiling of a novel orthotopic NSCLC model using scSPACE-Seq
Allonsius, L. (Speaker), Bardet, P. (Contributor), Hadadi, E. (Contributor), Kancheva, D. (Contributor), Debraekeleer, A. (Contributor), Marcq, E. (Contributor), Caro, A. A. (Contributor), Brughmans, J. (Contributor), Hamouda, A. E. I. (Contributor), Roelandt, R. (Contributor), Nana, F. A. (Contributor) & Laoui, D. (Contributor)
2024Activity: Talk or presentation › Talk or presentation at a conference