Projects per year
Personal profile
Expertise
Working in the field of preclinical nuclear and molecular diagnostics and cancer therapy using single-domain antibody fragments.
Education/Academic qualification
Doctoral Research, Nanobodies targeting mutant-EGFR as a unique tumor-restrictive vehicle for targeted therapy of glioblastoma, Research Foundation Flanders
1 Jan 2016 → 1 Jan 2020
Award Date: 16 Dec 2015
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Dive into the research topics where Janik Puttemans is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Projects
- 2 Finished
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ANI180: Nanobody-Based Targeted Radionuclide Therapy of Multiple Myeloma: a feasibilty study.
D'Huyvetter, M. (Administrative Promotor), Lahoutte, T. (Co-Promotor), Devoogdt, N. (Collaborator) & Puttemans, J. (Collaborator)
1/01/17 → 31/03/21
Project: Fundamental
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FWOSB12: FWO-SB-Beurs: Nanobodies targeting mutant-EGFR as a unique tumor-restrictive vehicle for targeted therapy of glioblastoma
Devoogdt, N. (Administrative Promotor) & Puttemans, J. (Mandate)
1/01/16 → 31/12/19
Project: Applied
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Anti-Idiotypic VHHs and VHH-CAR-T Cells to Tackle Multiple Myeloma: Different Applications Call for Different Antigen-Binding Moieties
Hanssens, H., Meeus, F., Gesquiere, E. L., Puttemans, J., Vlaeminck, Y. D., Veirman, K. D., Breckpot, K. & Devoogdt, N., 22 May 2024, In: International Journal of Molecular Sciences. 25, 11, 16 p., 5634.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)85 Downloads (Pure) -
Generation and Characterization of Novel Pan-Cancer Anti-uPAR Fluorescent Nanobodies as Tools for Image-Guided Surgery
Mateusiak, Ł., Floru, S., De Groof, T. W. M., Wouters, J., Declerck, N. B., Debie, P., Janssen, S., Zeven, K., Breckpot, K., Puttemans, J., Vincke, C., Devoogdt, N. & Hernot, S., Aug 2024, In: Advanced Science. 11, 30, 11 p., e2400700.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)90 Downloads (Pure) -
Scrutiny of chimeric antigen receptor activation by the extracellular domain: experience with single domain antibodies targeting multiple myeloma cells highlights the need for case-by-case optimization
Hanssens, H., Meeus, F., De Vlaeminck, Y., Lecocq, Q., Puttemans, J., Debie, P., De Groof, T. W. M., Goyvaerts, C., De Veirman, K., Breckpot, K. & Devoogdt, N., 19 Apr 2024, In: Frontiers in Immunology. 15, 18 p., 1389018.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)9 Downloads (Pure) -
Accepted poster session at ImmunoRad 2023: Targeted alpha therapy using Actinium-225 radiolabeled single domain antibodies induces antigen-specific immune responses and instills immunomodulation both systemically and at the tumor microenvironment
Ertveldt, T., Krasniqi, A., Ceuppens, H., Puttemans, J., Dekempeneer, Y., De Jonghe, K., de Mey, W., Lecocq, Q., De Vlaeminck, Y., Awad, R. M., Goyvaerts, C., De Veirman, K., Morgenstern, A., Bruchertseifer, F., Keyaerts, M., Devoogdt, N., D'Huyvetter, M. & Breckpot, K., 27 Sept 2023.Research output: Unpublished contribution to conference › Poster
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Intraoperative tumor visualization through a specific fluorescently-labeled anti-uPAR targeting single-domain antibody
Vangeloven, E., Mateusiak, L., Floru, S., De Groof, T., Declerck, N., Wouters, J., Janssen, S., Debie, P., Zeven, K., Vincke, C., Puttemans, J., Stroet, M., Ballet, S., Breckpot, K., Devoogdt, N. & Hernot, S., 2023, (Unpublished).Research output: Unpublished contribution to conference › Poster
Datasets
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Generation and Characterization of Novel Pan-Cancer Anti-uPAR Fluorescent Nanobodies as Tools for Image-Guided Surgery
Mateusiak, L. (Creator), Floru, S. (Researcher), De Groof, T. (Researcher), Wouters, J. (Researcher), Declerck, N. (Researcher), Debie, P. (Researcher), Janssen, S. (Researcher), Zeven, K. (Researcher), Puttemans, J. (Researcher), Vincke, C. (Researcher), Breckpot, K. (Project Member), Devoogdt, N. (Project Member) & Hernot, S. (Supervisor), Zenodo, 26 Mar 2025
DOI: https://zenodo.org/records/15089920
Dataset
Prizes
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Travel Grant Doctoral School VUB - LSM
Puttemans, J. (Recipient), 7 Sept 2016
Prize: Prize (including medals and awards)
Activities
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In vivo optical imaging using a novel fluorescently-labeled single-domain antibody targeting a universal tumor marker
Mateusiak, L. (Speaker), Floru, S. (Contributor), Wouters, J. (Contributor), De Groof, T. (Contributor), Declerck, N. (Contributor), Janssen, S. (Contributor), Debie, P. (Contributor), Zeven, K. (Contributor), Puttemans, J. (Contributor), Breckpot, K. (Contributor), Devoogdt, N. (Contributor) & Hernot, S. (Contributor)
28 Jan 2023Activity: Talk or presentation › Talk or presentation at a conference
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In vivo optical imaging of glioma using a novel uPAR-targeting fluorescent single-domain antibody
Mateusiak, L. (Speaker), Floru, S. (Contributor), De Groof, T. (Contributor), Declerck, N. (Contributor), Wouters, J. (Contributor), Janssen, S. (Contributor), Debie, P. (Contributor), Zeven, K. (Contributor), Vincke, C. (Contributor), Puttemans, J. (Contributor), Stroet, M. (Contributor), Breckpot, K. (Contributor), Devoogdt, N. (Contributor) & Hernot, S. (Contributor)
16 Mar 2023Activity: Talk or presentation › Talk or presentation at a conference
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MILabs Lunch Symposium - User Of The Year
Puttemans, J. (Speaker)
25 Aug 2021Activity: Talk or presentation › Talk or presentation at a conference
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Research stay: Radiolabeling of anti-5T33 sdAbs
Puttemans, J. (Participant)
14 Nov 2019 → 11 Dec 2019Activity: Other › Research and Teaching at External Organisation
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Workshop Immuno-Imaging and Molecular Therapy - Hands-on session: Nanobody lead selection analysis
Hanssens, H. (Speaker) & Puttemans, J. (Speaker)
5 Apr 2019Activity: Talk or presentation › Talk or presentation at a workshop/seminar
Thesis
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EGFRvIII Nb TRNT: Evaluation of radiolabeled nanobodies for the treatment of cancers expressing mutant EGFR’
Puttemans, J. ((PhD) Student), Devoogdt, N. (Promotor), D'Huyvetter, M. (Promotor) & Muyldermans, S. (Co-promotor), 4 Mar 2021Student thesis: Doctoral Thesis
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Evaluation of anti-idiotype Nanobodies in a preclinical model of Multiple Myeloma
Sharma, P. ((PhD) Student), Puttemans, J. (Advisor), Devoogdt, N. (Promotor), D'Huyvetter, M. (Co-promotor) & Muyldermans, S. (Co-promotor), 2019Student thesis: Master's Thesis
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Nanoparticles: The future of mRNA-based anticancer therapeutics
Puttemans, J. ((PhD) Student), Breckpot, K. (Promotor), Van Der Jeught, K. (Advisor) & Rediers, H. (Co-promotor), 9 Jun 2015Student thesis: Master's Thesis
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Radiolabeled single-domain antibody fragments for targeted radionuclide therapy of difficult-to-treat cancers.
Puttemans, J. ((PhD) Student), Devoogdt, N. (Promotor), D'Huyvetter, M. (Promotor), Orlova, A. (Jury), Descamps, B. (Jury), Menu, E. (Jury), Movahedi, K. (Jury) & Caveliers, V. (Jury), Devoogdt, N. (Promotor), D'Huyvetter, M. (Promotor), Orlova, A. (Jury), Descamps, B. (Jury), Menu, E. (Jury), Movahedi, K. (Jury) & Caveliers, V. (Jury), 4 Mar 2021Student thesis: Doctoral Thesis
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