Projects per year
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Collaborations and top research areas from the last five years
Projects
- 1 Active
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FWOTM1192: Targeting system xc- to simultaneously tackle the metabolic and neurological comorbidities of diet-induced obesity
Massie, A. (Administrative Promotor) & Walckiers, J. (Mandate)
1/11/23 → 31/10/27
Project: Fundamental
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An islet-resident macrophage antioxidant program preserves β cell physiology
Grosjean, A., Jalon, A., Leveau, C., Diedisheim, M., Bejarano, D. A., Cuenco, J., Mulder, K., Liu, Z., Le Guernic, A., Island, M.-L., Walckiers, J., Ates, G., Materne, C., Goncalves, A., Nemazanyy, I., Baudrin, L. G., Baulande, S., Ropert, M., Gautier, J.-F. & Hamaï, A. & 5 others, , 14 Nov 2025, In: Science immunology. 10, 113, 18 p., eadz5181.Research output: Contribution to journal › Article › peer-review
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System xc- deletion alters the metabolic phenotype of murine astrocytes
Ates, G., Vanonckelen, O., Mackens, L., Walckiers, J., Hideyo, S. & Massie, A., 2025, Volume 73: XVII European Meeting on Glial Cells in Health and Disease, Marseille, 8-11 July 2025. 17 ed. Wiley Online Library, Vol. 73. 1 p.Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)
Open Access -
System xc- deletion alters the metabolic phenotype of murine astrocytes in healthy and pathological aging.
Ates, G., Vanonckelen, O. (Contributor), Mackens, L. (Contributor), De Pauw, L. (Contributor), Adeyemi, J. O. (Contributor), Walckiers, J. (Contributor), Hideyo, S. (Contributor) & Massie, A., 2025, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Characterization of the long-term effects of lethal total body irradiation followed by bone marrow transplantation on the brain of C57BL/6 mice
Janssen, P., De Pauw, L., Mambretti, M., Lara, O., Walckiers, J., Mackens, L., Rooman, I., Guillaume, B., De Ridder, M., Ates, G. & Massie, A., 3 Mar 2024, In: International Journal of Radiation Biology. 100, 3, p. 385-398 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)91 Downloads (Pure) -
Compartmentalized role of xCT in supporting pancreatic tumor growth, inflammation and mood disturbance in mice
Lara, O., Janssen, P., Mambretti, M., De Pauw, L., Ates, G., Mackens, L., De Munck, J., Walckiers, J., Pan, Z., Beckers, P., Espinet, E., Sato, H., De Ridder, M., Marks, D. L., Barbé, K., Aerts, J., Hermans, E., Rooman, I. & Massie, A., May 2024, In: Brain, Behavior, and Immunity. 118, p. 275-286 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)54 Downloads (Pure)
Activities
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Targeting system xc- to simultaneously tackle the metabolic and neurological comorbidities of diet-induced obesity
Walckiers, J. (Speaker), Dalmas, E. (Contributor), Vanonckelen, O. (Contributor), Mackens, L. (Contributor), Van Mulders, A. (Contributor), Dreessen, T. (Contributor), Staels, W. (Contributor), De Leu, N. (Contributor), Ates, G. (Contributor) & Massie, A. (Contributor)
20 Oct 2025Activity: Talk or presentation › Talk or presentation at a conference
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System xc- inhibition to preserve mitochondrial health in aging and Alzheimer’s disease
Ates, G. (Speaker), Adeyemi, J. O. (Contributor), De Pauw, L. (Contributor), Mackens, L. (Contributor), Walckiers, J. (Contributor), Vanonckelen, O. (Contributor), Janssen, P. (Contributor), Lara, O. (Contributor), Sato, H. (Contributor) & Massie, A. (Contributor)
6 Jun 2023Activity: Talk or presentation › Talk or presentation at a conference
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System xc- inhibition to preserve metabolic health in Alzheimer’s disease.
Ates, G. (Presenter), Adeyemi, J. O. (Contributor), De Pauw, L. (Contributor), Mackens, L. (Contributor), Walckiers, J. (Contributor), Vanonckelen, O. (Contributor), Janssen, P. (Contributor), Lara, O. (Contributor), Hideyo, S. (Contributor) & Massie, A. (Contributor)
11 Nov 2023 → 15 Nov 2023Activity: Talk or presentation › Talk or presentation at a conference
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System xc- inhibition to preserve mitochondrial health in aging and Alzheimer’s disease
Ates, G. (Speaker), Adeyemi, J. O. (Contributor), De Pauw, L. (Contributor), Mackens, L. (Contributor), Walckiers, J. (Contributor), Vanonckelen, O. (Contributor), Janssen, P. (Contributor), Lara, O. (Contributor), Hideyo, S. (Contributor) & Massie, A. (Contributor)
6 Jun 2023Activity: Talk or presentation › Talk or presentation at a conference
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Charity Quiz PhD United 2023
Vandewalle, N. (Organiser), Geirnaert, F. (Organiser), Wyns, A. (Organiser), Muylaert, C. (Organiser), Walckiers, J. (Organiser), Lobo, M. (Organiser), Vanonckelen, O. (Organiser), Van Hemelrijck, L. A. (Organiser), Van Campenhout, J. (Organiser), Van der Vliet, M. (Organiser), Hanssens, H. (Organiser), Janssens, C. (Organiser), De Coster, M. (Organiser), Van den Bossche, J.-L. (Organiser) & Coolens, K. (Organiser)
14 Dec 2023Activity: Participating in or organising an event › Participating in or organizing a school event
Thesis
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Age-related reductive stress and metabolic flexibility in system Xc--deficient mice
Walckiers, J. ((PhD) Student) & Massie, A. (Promotor), Massie, A. (Promotor) & Ates, G. (Promotor), 24 May 2022Student thesis: Master's Thesis