Projects per year
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
Projects
- 1 Finished
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Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity
Martin, E., Giakoumakis, D., Paesmans, J., Bisi, N., Drozdzecki, A., Audenaert, D., Haustraete, J., Verstreken, P., Galicia, C., Ballet, S. & Versées, W., 12 Sept 2025, In: ACS Pharmacology and Translational Science. 8, 9, p. 2996-3006 11 p.Research output: Contribution to journal › Article › peer-review
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Synaptojanin1: From Structural Insights to Therapeutic Targeting
Martin, E., Paesmans, J., Berghmans, M., Giakoumakis, D., Galicia Diaz Santana, C. & Versées, W., 2025.Research output: Unpublished contribution to conference › Poster
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Structural and functional insights in Synaptojanin1 and its implication in disease
Martin, E., Paesmans, J., Berghmans, M., Galicia Diaz Santana, C. & Versées, W., 13 May 2024, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Compounds for treatment of intractable epilepsy and doors syndrome
Verstreken, P., Lüthy, K., Versées, W., Fischer, B. & Paesmans, J., 2023, Patent No. EP3503880Research output: Patent
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Ontrafeling van de structuur en functie van de synaptische eiwitten TBC1D24 en Synaptojanin1 en hun rol in neurologische aandoeningen
Paesmans, J., 2021Research output: Thesis › PhD Thesis
Datasets
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Discovery and characterization of a selective inhibitor of Synaptojanin1 5-phosphatase activity
Martin, E. (Creator), Giakoumakis, D. (Creator), Paesmans, J. (Creator), Bisi, N. (Creator), Drozdzecki, A. (Creator), Audenaert, D. (Creator), Haustraete, J. (Creator), Verstreken, P. (Creator), Galicia Diaz Santana, C. (Creator), Ballet, S. (Creator) & Versées, W. (Creator), Zenodo, 12 Sept 2025
Dataset
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Crystal structure of the TLDc domain of Skywalker/TBC1D24 from Drosophila melanogaster
Versées, W. (Project Leader), Fischer, B. (Creator) & Paesmans, J. (Researcher), Protein Data Bank in Europe, 17 Jul 2019
DOI: 10.2210/pdb6R82/pdb
Dataset
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Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody.
Paesmans, J. (Creator), Versées, W. (Supervisor), Galicia Diaz Santana, C. (Creator) & Martin, E. (Creator), Protein Data Bank in Europe, 30 Dec 2020
DOI: 10.2210/pdb7A17/pdb
Dataset
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Crystal structure of the 5-phosphatase domain of Synaptojanin1 in complex with a nanobody
Paesmans, J. (Creator), Versées, W. (Supervisor), Galicia Diaz Santana, C. (Creator) & Martin, E. (Creator), Protein Data Bank in Europe, 30 Dec 2020
DOI: 10.2210/pdb7A0V/pdb
Dataset
Activities
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Science on the road
Jone Paesmans (Speaker)
14 Feb 2020Activity: Talk or presentation › Talk at a school event
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Science on the road
Jone Paesmans (Speaker)
13 Feb 2020Activity: Talk or presentation › Talk at a school event
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Science on the road
Jone Paesmans (Speaker)
11 Jan 2019Activity: Talk or presentation › Talk at a school event
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Science on the road
Jone Paesmans (Speaker)
8 Feb 2019Activity: Talk or presentation › Talk at a school event
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Science on the road
Jone Paesmans (Speaker)
16 Mar 2018Activity: Talk or presentation › Talk at a school event
Thesis
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Karakterisering van domein- en conformatie-specifieke Nanobodies gericht tegen een bacterieel homoloog van het LRRK2-eiwit
Author: Paesmans, J., 30 Jun 2014Supervisor: Versees, W. (Promotor), Steyaert, J. (Co-promotor), Muyldermans, S. (Jury) & Vanderheyden, P. (Jury)
Student thesis: Master's Thesis
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Unraveling the structure and function of the synaptic proteins TBC1D24 and Synaptojanin1 and their role in neurological disorders
Author: Paesmans, J., Versées, W., Ballet, S., Brunner, J., Smolders, I., Greggio, E., Ismail, S. & Galicia Diaz Santana, C., 29 Jun 2021Student thesis: Doctoral Thesis