Projects per year
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Projects
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FWOTM1016: The impact of recurrent chromosomal abnormalities on growth advantage and differentiation capacity of human pluripotent stem cells
Krivec, N., Spits, C. & Sermon, K.
1/11/20 → 31/10/22
Project: Fundamental
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ANI253: Functional research of genes involved in the development of the brain
Jansen, A., Stouffs, K., Sermon, K., Gheldof, A. & Yildirim, H.
1/10/20 → 30/09/22
Project: Fundamental
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FWOTM968: The search for the origin of chromosomal abnormalities in human preimplantation embryos
Sermon, K., Spits, C. & Regin, M.
1/10/19 → 31/10/21
Project: Fundamental
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FWOSB55: A roadmap to the safe introduction of hESC in the clinic: the case of genetic mosaicism in hESC-derived retinal cells
Couvreu De Deckersberg, E., Spits, C. & Sermon, K.
1/01/19 → 31/12/22
Project: Fundamental
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HERC45: FWO Hercules MZW: Light sheet fluorescence microscopy in life sciences and medical research
Sermon, K., Van De Velde, H., Goossens, E., Baeyens, L., Van Ginderachter, J., De Bundel, D., Hernot, S., De Kock, J., Vinken, M., Vanhaecke, T., Marcelino Rodrigues, R. & van Grunsven, L.
1/05/18 → 30/04/22
Project: Fundamental
Research output
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Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm
Dziedzicka, D., Tewary, M., Keller, A., Tilleman, L., Prochazka, L., Östblom, J., Couvreu De Deckersberg, E., Markouli, C., Franck, S., Van Nieuwerburgh, F., Spits, C., Zandstra, P. W., Sermon, K. & Geens, M., 2021, In : Scientific Reports. 11, 1, 14 p., 6137.Research output: Contribution to journal › Article
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MSH2 knock-down shows CTG repeat stability and concomitant upstream demethylation at the DMPK locus in myotonic dystrophy type 1 human embryonic stem cells
Franck, S., Barbé, L., Ardui, S., De Vlaeminck, Y., Allemeersch, J., Dziedzicka, D., Spits, C., Vanroye, F., Hilven, P., Duqué, G., Vermeesch, J. R., Gheldof, A. & Sermon, K., 6 Jan 2021, In : Human Molecular Genetics. 29, 21, p. 3566-3577 12 p.Research output: Contribution to journal › Article
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Sustained intrinsic WNT and BMP4 activation impairs hESC differentiation to definitive endoderm and drives the cells towards extra-embryonic mesoderm
Markouli, C., Couvreu De Deckersberg, E., Dziedzicka, D. A., Regin, M., Franck, S., Keller, A. S., Gheldof, A., Geens, M., Sermon, K. & Spits, C., 15 Apr 2021, In : Scientific Reports - Nature. 11Research output: Contribution to journal › Article
Open Access -
An economic analysis of preimplantation genetic testing for aneuploidy by polar body biopsy in advanced maternal age
Neumann, K., Sermon, K., Bossuyt, P., Goossens, V., Geraedts, J., Traeger-Synodinos, J., Parriego, M., Schmutzler, A., van der Ven, K., Rudolph-Rothfeld, W., Vonthein, R. & Griesinger, G., 2020, In : British Journal of Obstetrics and Gynaecology. 127, 6, p. 710-718 9 p.Research output: Contribution to journal › Article
3 Citations (Scopus) -
The association of CTDP1 mutation with malformations of cortical development
Yildirim, H., Kerkhove, L., Dimitrov, B., Cannaerts, E., Sermon, K., Stouffs, K. & Jansen, A., 6 Mar 2020.Research output: Unpublished contribution to conference › Poster
Prizes
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Award-winning oral presentation
Karen Sermon (Recipient), 21 Jun 1998
Prize: Prize (including medals and awards)
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Activities
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Differences in the landscape of mitochondrial DNA variants between ART and spontaneously conceived individuals links to maternal infertility and low birth weight
Joke Mertens (Speaker), Filippo Zambelli (Contributor), Florence Belva (Contributor), Aafke PA van Montfoort (Contributor), Edouard Couvreu De Deckersberg (Contributor), Mary-Louise Bonduelle (Contributor), Katrien Stouffs (Contributor), Sara Seneca (Contributor), Hilde Van De Velde (Contributor), Christophe Blockeel (Contributor), Karen Sermon (Contributor), Claudia Spits (Contributor)5 Jul 2020 → 8 Jul 2020Activity: Talk or presentation › Talk or presentation at a conference
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Maternally inherited differences in mitochondrial DNA genotype between ART and spontaneously conceived individuals are aggravated by controlled ovarian stimulation and link to low birth weight
Joke Mertens (Speaker), Florence Belva (Contributor), Aafke PA van Montfoort (Contributor), Filippo Zambelli (Contributor), Edouard Couvreu De Deckersberg (Contributor), Mary-Louise Bonduelle (Contributor), Herman Tournaye (Contributor), Katrien Stouffs (Contributor), Sara Seneca (Contributor), Kurt Barbé (Contributor), Hubert J M Smeets (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor), Christophe Blockeel (Contributor), Claudia Spits (Contributor)28 Nov 2020Activity: Talk or presentation › Talk or presentation at a conference
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Mitochondrial DNA mosaicism in early human development
Joke Mertens (Speaker), Marius Regin (Contributor), Neelke De Munck (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor), Claudia Spits (Contributor)25 Jun 2019Activity: Talk or presentation › Talk or presentation at a conference
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Mitochondrial DNA mosaicism in early human development
Joke Mertens (Speaker), Marius Regin (Contributor), Neelke De Munck (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor), Christophe Blockeel (Contributor), Claudia Spits (Contributor)22 Nov 2019 → 23 Nov 2019Activity: Talk or presentation › Talk or presentation at a conference
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Polar body chromosome analysis: a viable alternative in PGS?
Karen Sermon (Speaker)1 Nov 2018Activity: Talk or presentation › Talk or presentation at a workshop/seminar
Press / Media
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Nederlandse wetenschappers maken voor het eerst embryo’s uit stamcellen
4/05/18
1 Media contribution
Press/Media: Expert Comment
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Vorsers kweken hamburger met stamcellen (Researchers make hamburger out of stem cells)
4/08/13
1 Media contribution
Press/Media: Other
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Thesis
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(R)evolution in preimplantation genetic diagnosis : development and clinical application of different approaches to preimplantation genetic diagnosis for monogenic disorders.
Author: Spits, C., Liebaers, I., Sermon, K., De Rycke, M., Van Schravendijk, C., Van Der Auwera, B., Geraedts, J., Harper, J., Santalo Pedro, J., De Paepe, A., Legius, E. & Timmerman, V., 4 Dec 2006Supervisor: Liebaers, I. (Promotor), Sermon, K. (Co-promotor), De Rycke, M. (Co-promotor), Van Schravendijk, C. (Jury), Van Der Auwera, B. (Jury), Geraedts, J. (External person) (Jury), Harper, J. (External person) (Jury), Santalo Pedro, J. (External person) (Jury), De Paepe, A. (External person) (Jury), Legius, E. (External person) (Jury) & Timmerman, V. (External person) (Jury)
Student thesis: Doctoral Thesis
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Cell culture and differentiation of embryonic stem cells for bone tissue engineering
Author: Tielens, S., Cornelissen, R. & Sermon, K., 20 Nov 2007Supervisor: Sermon, K. (Jury) & Cornelissen, R. (External person) (Promotor)
Student thesis: Doctoral Thesis
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Characterisation of the molecular causes and selective advantages of chromosome abnormalities in human embryonic stem cells
Author: Nguyen Thi, H., Sermon, K. & Spits, C., 2 Sep 2010Supervisor: Sermon, K. (Promotor) & Spits, C. (Advisor)
Student thesis: Master's Thesis
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Chromosomal abnormalities in human preimplantation development
Author: Mertzanidou, A., Spits, C., Sermon, K., Van Schravendijk, C., Breckpot, K., De Rycke, M., Verpoest, W., Wells, D. & Debrock, S., 29 Apr 2015Supervisor: Sermon, K. (Promotor), Spits, C. (Promotor), Van Schravendijk, C. (Jury), Breckpot, K. (Jury), De Rycke, M. (Jury), Verpoest, W. (Jury), Wells, D. (External person) (Jury) & Debrock, S. (External person) (Jury)
Student thesis: Doctoral Thesis
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Cumulus cell gene expression as a marker of oocyte quality in the IVF laboratory
Author: Wathlet, S., Smitz, J., Sermon, K., Viville, S., De Meirleir, L., Vinken, M. & Heindryckx, B., 19 Feb 2013Supervisor: Smitz, J. (Promotor), Sermon, K. (Jury), Viville, S. (External person) (Jury), De Meirleir, L. (Jury), Vinken, M. (Jury) & Heindryckx, B. (External person) (Jury)
Student thesis: Doctoral Thesis