Projects per year
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Dive into the research topics where Karen Sermon is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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FWOAL1043: Exploring the first lineage segregation in the human embryo: is GATA3 the gatekeeper of trophectoderm differentiation?
Van De Velde, H. & Sermon, K.
1/01/22 → 31/12/25
Project: Fundamental
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FWOTM1016: The impact of recurrent chromosomal abnormalities on growth advantage and differentiation capacity of human pluripotent stem cells
Krivec, N., Spits, C. & Sermon, K.
1/11/20 → 31/10/22
Project: Fundamental
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ANI253: Functional research of genes involved in the development of the brain
Jansen, A., Stouffs, K., Sermon, K., Gheldof, A. & Yildirim, H.
1/10/20 → 30/09/22
Project: Fundamental
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FWOSB55: A roadmap to the safe introduction of hESC in the clinic: the case of genetic mosaicism in hESC-derived retinal cells
Couvreu De Deckersberg, E., Spits, C. & Sermon, K.
1/01/19 → 31/12/22
Project: Fundamental
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OZRMETH3: Research at the interface between human genetics and reproduction.
Sermon, K., Seneca, S., Bonduelle, M., De Rycke, M., Devroey, P., Goossens, E., Lissens, W., Spits, C., Stouffs, K., Tournaye, H., Dee, K., Vandermaelen, D., Van Haute, L., Van Saen, D., Van Den Abbeel, E., Liebaers, I., De Meirleir, L., Nekkebroeck, J. & Van De Velde, H.
1/01/09 → 31/12/22
Project: Fundamental
Research output
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Dysfunctional CTDP1 impairs the cell cycle indicating its essential role in neurodevelopment
Yildirim, H., Dimitrov, B., Cannaerts, E., Sermon, K., Gheldof, A., Stouffs, K. & Jansen, A., 2022.Research output: Unpublished contribution to conference › Poster
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Impaired catabolism of free oligosaccharides due to MAN2C1 variants causes a neurodevelopmental disorder
Maia, N. M. M., Potelle, S., Yildirim, H., Duvet, S., Akula, S. K., Schulz, C., Wiame, E., Gheldof, A., O'kane, K., Lai, A., Sermon, K., Proisy, M., Loget, P., Attié-Bitach, T., Quélin, C., Fortuna, A. M., Soares, A. R., de Brouwer, A. P. M., Van Schaftingen, E., Marie-Cécile, N. & 5 others, , 3 Feb 2022, In : American Journal of Human Genetics. 109, 2, p. 345-360 16 p.Research output: Contribution to journal › Article
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Mitochondrial DNA variants segregate during human preimplantation development into genetically different cell lineages that are maintained postnatally
Mertens, J., Regin, M., De Munck, N., de Deckersberg, E. C., Belva, F., Sermon, K., Tournaye, H., Blockeel, C., Van de Velde, H. & Spits, C., 2022, In : Human Molecular Genetics.Research output: Contribution to journal › Article
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Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing
Franck, S., Couvreu De Deckersberg, E., Bubenik, J. L., Markouli, C., Barbé, L., Allemeersch, J., Hilven, P., Duqué, G., Swanson, M. S., Gheldof, A., Spits, C. & Sermon, K. D., 15 Jan 2022, In : Biology open. 11, 1, bio058978.Research output: Contribution to journal › Article
Open Access2 Citations (Scopus) -
On the origins and fate of chromosomal abnormalities in human preimplantation embryos: an unsolved riddle
Regin, M., Spits, C. & Sermon, K., 11 Apr 2022, In : Molecular Human Reproduction. 28, 4, 39 p., gaac011.Research output: Contribution to journal › Scientific review
Open Access
Prizes
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Award-winning oral presentation
Karen Sermon (Recipient), 21 Jun 1998
Prize: Prize (including medals and awards)
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Activities
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Maternally inherited differences in mitochondrial DNA genotype between ART and spontaneously conceived individuals associate with low birthweight
Joke Mertens (Speaker), Florence Belva (Contributor), Aafke PA van Montfoort (Contributor), Filippo Zambelli (Contributor), Sara Seneca (Contributor), Edouard Couvreu De Deckersberg (Contributor), Mary-Louise Bonduelle (Contributor), Herman Tournaye (Contributor), Katrien Stouffs (Contributor), Kurt Barbé (Contributor), Hubert J M Smeets (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor), Christophe Blockeel (Contributor), Claudia Spits (Contributor)30 Jun 2021Activity: Talk or presentation › Talk or presentation at a conference
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Aneuploidy induces proteotoxic stress and autophagy-mediated apoptosis in human preimplantation embryos
Marius Regin (Speaker), Yingnan Lei (Contributor), Edouard Couvreu De Deckersberg (Contributor), Yves Guns (Contributor), Pieter Verdyck (Contributor), Greta Verheyen (Contributor), Hilde Van De Velde (Contributor), Claudia Spits (Contributor), Karen Sermon (Contributor)26 Nov 2021 → 27 Nov 2021Activity: Talk or presentation › Talk or presentation at a conference
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Aneuploidy induces proteotoxic stress and autophagy-mediated apoptosis in human preimplantation embryos
Marius Regin (Speaker), Edouard Couvreu De Deckersberg (Contributor), Yves Guns (Contributor), Pieter Verdyck (Contributor), Greta Verheyen (Contributor), Hilde Van De Velde (Contributor), Claudia Spits (Contributor), Karen Sermon (Contributor)1 Jul 2021Activity: Talk or presentation › Talk or presentation at a conference
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Mitochondrial DNA mosaicism in early human development
Joke Mertens (Speaker), Marius Regin (Contributor), Neelke De Munck (Contributor), Edouard Couvreu De Deckersberg (Contributor), Christophe Blockeel (Contributor), Herman Tournaye (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor), Claudia Spits (Contributor)17 Sep 2021Activity: Talk or presentation › Talk or presentation at a conference
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21st Annual Meeting of the Belgium Society for Human Genetics
Maria Filomena Cuevas Y Bretones (Organiser), Karen Sermon (Member of programme committee), Thomy de Ravel (Member of programme committee), Willem Verpoest (Member of programme committee), Catharina Olsen (Member of programme committee), Hilde Van De Velde (Member of programme committee), Freya Vaeyens (Member of programme committee), Kathelijn Keymolen (Organiser), Ken Maes (Organiser), Pieter Verdyck (Organiser), Veerle Berckmoes (Organiser), Kim Van Berkel (Organiser), Frederik Jan Hes (Chair), Florence Belva (Participant), Marleen Carlé (Participant), Aranza Cortes Jauregui (Participant), Pascale De Becker (Participant), Jacques De Grève (Participant), Martine De Rycke (Chair), Elke De Schutter (Participant), Simon Denil (Participant), Boyan Dimitrov (Participant), Elia Fernandez Gallardo (Participant), Annelies Fieuw (Participant), Alexander Gheldof (Participant), Philippe Giron (Participant), Ingeborg Liebaers (Member of programme committee), Eva Sammels (Participant), Sara Seneca (Participant), Ileen Slegers (Participant), Katrien Stouffs (Chair), Sophie Uyttebroeck (Participant), Annelore Van Der Kelen (Participant), Andre Van Steirteghem (Member of programme committee), Elise Vantroys (Participant), Boyan Dimitrov (Participant)17 Sep 2021Activity: Participating in or organising an event › Participating in or organizing an event at an external academic organisation
Press / Media
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Nederlandse wetenschappers maken voor het eerst embryo’s uit stamcellen
4/05/18
1 Media contribution
Press/Media: Expert Comment
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Vorsers kweken hamburger met stamcellen (Researchers make hamburger out of stem cells)
4/08/13
1 Media contribution
Press/Media: Other
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Thesis
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(R)evolution in preimplantation genetic diagnosis : development and clinical application of different approaches to preimplantation genetic diagnosis for monogenic disorders.
Author: Spits, C., Liebaers, I., Sermon, K., De Rycke, M., Van Schravendijk, C., Van Der Auwera, B., Geraedts, J., Harper, J., Santalo Pedro, J., De Paepe, A., Legius, E. & Timmerman, V., 4 Dec 2006Supervisor: Liebaers, I. (Promotor), Sermon, K. (Co-promotor), De Rycke, M. (Co-promotor), Van Schravendijk, C. (Jury), Van Der Auwera, B. (Jury), Geraedts, J. (External person) (Jury), Harper, J. (External person) (Jury), Santalo Pedro, J. (External person) (Jury), De Paepe, A. (External person) (Jury), Legius, E. (External person) (Jury) & Timmerman, V. (External person) (Jury)
Student thesis: Doctoral Thesis
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Cell culture and differentiation of embryonic stem cells for bone tissue engineering
Author: Tielens, S., Cornelissen, R. & Sermon, K., 20 Nov 2007Supervisor: Sermon, K. (Jury) & Cornelissen, R. (External person) (Promotor)
Student thesis: Doctoral Thesis
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Characterisation of the molecular causes and selective advantages of chromosome abnormalities in human embryonic stem cells
Author: Nguyen Thi, H., Sermon, K. & Spits, C., 2 Sep 2010Supervisor: Sermon, K. (Promotor) & Spits, C. (Advisor)
Student thesis: Master's Thesis
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Chromosomal abnormalities in human preimplantation development
Author: Mertzanidou, A., Spits, C., Sermon, K., Van Schravendijk, C., Breckpot, K., De Rycke, M., Verpoest, W., Wells, D. & Debrock, S., 29 Apr 2015Supervisor: Sermon, K. (Promotor), Spits, C. (Promotor), Van Schravendijk, C. (Jury), Breckpot, K. (Jury), De Rycke, M. (Jury), Verpoest, W. (Jury), Wells, D. (External person) (Jury) & Debrock, S. (External person) (Jury)
Student thesis: Doctoral Thesis
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Cumulus cell gene expression as a marker of oocyte quality in the IVF laboratory
Author: Wathlet, S., Smitz, J., Sermon, K., Viville, S., De Meirleir, L., Vinken, M. & Heindryckx, B., 19 Feb 2013Supervisor: Smitz, J. (Promotor), Sermon, K. (Jury), Viville, S. (External person) (Jury), De Meirleir, L. (Jury), Vinken, M. (Jury) & Heindryckx, B. (External person) (Jury)
Student thesis: Doctoral Thesis