Projects per year
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Collaborations and top research areas from the last five years
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HERC66: 3D-CELLMAP: Unveiling complex cellular interactions in tissues through 3D super-resolution protein multiplex imaging
Movahedi, K., Rooman, I., Sermon, K., De Bundel, D., Fioravanti, A., Staels, W., Magez, S., Breckpot, K., De Kock, J., Laoui, D., Goyvaerts, C., Smolders, I., Van Ginderachter, J., Marcelino Rodrigues, R., De Leu, N., van Grunsven, L., Hernot, S., Peeters, E., Vanhaecke, T., De Veirman, K., Ruytinx, J., Van Schependom, J., Kortekaas, I. & Goossens, E.
1/05/24 → 31/05/28
Project: Fundamental
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BASGO23: OZR Basisfinanciering voor Grote Onderzoeksgroepen - GRAD
1/01/24 → 31/12/29
Project: Fundamental
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OZRMETH9: The Genetic Component to Infertility and Early Developmental Failure
1/01/23 → 31/12/29
Project: Fundamental
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FWOTM1140: Identifying causes of emergence of chromosomal abnormalities in human cleavage stage embryos.
Sermon, K., Van De Velde, H. & Janssens, C.
1/11/22 → 31/10/26
Project: Fundamental
Research output
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Loss of 18q Alters TGFβ Signalling Affecting Anteroposterior Neuroectodermal Fate in Human Embryonic Stem Cells
lei, Y., Duong, C. M., Krivec, N., Janssens, C., Regin, M., Huyghebaert, A., Deckersberg, E. C. D., Sermon, K., Delbany, D. A. & Spits, C., 5 Feb 2025, In: Cell Proliferation. 12 p., e13813.Research output: Contribution to journal › Article › peer-review
Open Access -
The interplay between mitochondrial DNA genotypes, female infertility, ovarian response and mutagenesis in oocytes
Van Der Kelen, A., Li Piani, L., Mertens, J., Regin, M., Couvreu De Deckersberg, E., Van De Velde, H., Sermon, K., Tournaye, H., Verpoest, W., Hes, F. J., Blockeel, C. & Spits, C., 2025, In: Human reproduction open. 2025, 1, 13 p., hoae074.Research output: Contribution to journal › Article › peer-review
Open Access -
Aneuploidy as a first genetic hit that enhances the tumorigenic capacity of differentiated human pluripotent stem cells.
Al Delbany, D., Myrthe Mampay , Adhithya Narayanan Srinivasan, Krivec, N., Huyghebaert, A., Lei, Y., Sermon, K., Movahedi, K. & Spits, C., 29 Nov 2024, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Children born after assisted reproduction more commonly carry a mitochondrial genotype associating with low birthweight
Spits, C., Mertens, J., Belva, F., van Montfoort, A. PA., Regin, M., Zambelli, F., Seneca, S., Couvreu De Deckersberg, E., Bonduelle, M-L., Tournaye, H., Stouffs, K., Barbé, K., Smeets, B., Van De Velde, H., Sermon, K. & Blockeel, C., 9 Feb 2024, In: Nature Communications. 15, 1, 16 p., 1232 .Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)15 Downloads (Pure) -
Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos
Regin, M., Lei, Y., Couvreu De Deckersberg, E., Janssens, C., Huyghebaert, A., Guns, Y., Verdyck, P., Verheyen, G., Van de Velde, H., Sermon, K. & Spits, C., 9 Dec 2024, In: eLife. 12, 24 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus)
Datasets
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De Novo Cancer Mutations Frequently Associate with Recurrent Chromosomal Abnormalities during Long-Term Human Pluripotent Stem Cell Culture
Al Delbany, D. (Creator), Ghosh, M. (Creator), Krivec, N. (Creator), Huyghebaert, A. (Creator), Regin, M. (Creator), Duong, C. M. (Creator), Lei, Y. (Creator), Sermon, K. (Creator), Olsen, C. (Creator) & Spits, C. (Creator), OSF, 2024
Dataset
Prizes
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Award-winning oral presentation
Sermon, Karen (Recipient), 21 Jun 1998
Prize: Prize (including medals and awards)
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Activities
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Regulators of cell fate decisions in human pre-implantation embryos (Event)
Luc Leyns (Jury), Marius Regin (Presenter), Karen Sermon (Supervisor) & Claudia Spits (Supervisor)
28 Mar 2024Activity: Membership › Member of PhD committee
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Abstract citation ID: dead093.048 O-307 Aneuploidy in oocytes of women of advanced maternal age: impact on embryo development and evidence for a novel mechanism of meiotic error
Pieter Verdyck (Invited speaker), Gheona Altarescu (Contributor), Samuel Dos Santos Ribeiro (Contributor), C Vrettou (Speaker), Ulrich Koehler (Speaker), Georg Griesinger (Contributor), V. Goossens (Contributor), Maria-Cristina Magli (Contributor), C ALBANESE (Contributor), Monica Parriego (Contributor), L. Coll (Contributor), Raphael Ron-El (Contributor), Karen Sermon (Contributor) & Jan Traeger-Synodinos (Contributor)
26 Jun 2023Activity: Talk or presentation › Talk or presentation at a conference
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Aneuploidy induces proteotoxic stress and autophagy-mediated apoptosis in human preimplantation embryos
Marius Regin (Speaker), Edouard Couvreu De Deckersberg (Contributor), Yves Guns (Contributor), Pieter Verdyck (Contributor), Greta Verheyen (Contributor), Hilde Van De Velde (Contributor), Claudia Spits (Contributor) & Karen Sermon (Contributor)
1 Jul 2021Activity: Talk or presentation › Talk or presentation at a conference
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21st Annual Meeting of the Belgium Society for Human Genetics
Maria Filomena Cuevas Y Bretones (Organiser), Karen Sermon (Member of programme committee), Thomy de Ravel (Member of programme committee), Willem Verpoest (Member of programme committee), Catharina Olsen (Member of programme committee), Hilde Van De Velde (Member of programme committee), Freya Vaeyens (Member of programme committee), Kathelijn Keymolen (Organiser), Ken Maes (Organiser), Pieter Verdyck (Organiser), Veerle Berckmoes (Organiser), Kim Van Berkel (Organiser), Frederik Jan Hes (Chair), Florence Belva (Participant), Marleen Carlé (Participant), Aranza Cortes Jauregui (Participant), Pascale De Becker (Participant), Jacques De Grève (Participant), Martine De Rycke (Chair), Elke De Schutter (Participant), Simon Denil (Participant), Boyan Dimitrov (Participant), Elia Fernandez Gallardo (Participant), Annelies Fieuw (Participant), Alexander Gheldof (Participant), Philippe Giron (Participant), Ingeborg Liebaers (Member of programme committee), Eva Sammels (Participant), Sara Seneca (Participant), Ileen Slegers (Participant), Katrien Stouffs (Chair), Sophie Uyttebroeck (Participant), Annelore Van Der Kelen (Participant), Andre Van Steirteghem (Member of programme committee), Elise Vantroys (Participant) & Boyan Dimitrov (Participant)
17 Sep 2021Activity: Participating in or organising an event › Participating in or organizing an event at an external academic organisation
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Mitochondrial DNA mosaicism in early human development
Joke Mertens (Speaker), Marius Regin (Contributor), Neelke De Munck (Contributor), Edouard Couvreu De Deckersberg (Contributor), Christophe Blockeel (Contributor), Herman Tournaye (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor) & Claudia Spits (Contributor)
17 Sep 2021Activity: Talk or presentation › Talk or presentation at a conference
Press/Media
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Nederlandse wetenschappers maken voor het eerst embryo’s uit stamcellen
4/05/18
1 Media contribution
Press/Media: Expert Comment
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Vorsers kweken hamburger met stamcellen (Researchers make hamburger out of stem cells)
4/08/13
1 Media contribution
Press/Media: Other
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Thesis
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Effect of (specific) chromosomal aberrations on the differentiation potential and malignancy propensity of hESC
Author: Markouli, C., Sermon, K. & Geens, M., 2013Supervisor: Geens, M. (Promotor)
Student thesis: Master's Thesis
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Human embryonic stem cells: different shades of pluripotency and differentiation potential
Author: Duggal, G., De Sutter, P., Deforce, D., Heindryckx, B., Chuva de Sousa Lopes, S. & Sermon, K., 26 Feb 2015Student thesis: Doctoral Thesis
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Human Pancreatic Acinar Cell Plasticity.
Author: Baldan, J., Arnes, L., Jacquemin, P., Spits, C., Heimberg, H., Sermon, K. & Bouwens, L., 28 Sep 2020Supervisor: Arne, L. (External person) (Jury), Jacquemin, P. (External person) (Jury), Spits, C. (Jury), Heimberg, H. (External person) (Jury), Segers, K. (Jury) & Bouwens, L. (Promotor)
Student thesis: Doctoral Thesis
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In vitro gametogenesis. An inquiry into the main ethical concerns and why they matter
Author: Segers, S. & Sermon, K., 28 May 2019Supervisor: Pennings, G. (External person) (Promotor) & Mertes, H. (External person) (Promotor)
Student thesis: Doctoral Thesis
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Losing Balance. Investigating the prevalence and impact of chromosomal instability during early human development
Author: Sermon, K. & Popovic, M., 20 Sep 2019Supervisor: De Sutter, P. (External person) (Promotor) & Heindryckx, B. (External person) (Promotor)
Student thesis: Doctoral Thesis