Karine Breckpot
  • Laarbeeklaan 103

    1090 Brussels

    Belgium

  • Source: Scopus
  • Calculated based on no. of publications stored in Pure and citations from Scopus
1970 …2021

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Personal profile

Expertise

Design of innovative immunotherapy strategies. The strategies under development include ex vivo and in vivo engineering of (1) dendritic cells for immune activation and (2) T-cells for cancer cell rejection, and (3) engineering of the tumor microenvironment to facilitate antitumor immune responses. Technologies such as mRNA, lentiviral vectors and single domain antibodies (better known as nanobodies) are employed for these purposes. Strategies under development are extensively tested in preclinical in vitro models using cells of human and mouse origin as well as in mouse cancer models. Successful strategies are translated towards clinical applications in phase I/II trials.

Research interests

Cancer immunology and immunotherapy:

- Cancer vaccination

- T-cell therapy

- Immune checkpoint therapy

Education/Academic qualification

Education, Educational Professionalisation Pathway for Teaching Staff, Vrije Universiteit Brussel

Languages, Certificate CEFR level C1 (Academic English), Ghent University

Medical Sciences, PhD, Vrije Universiteit Brussel

Biomedical Sciences, Master, Vrije Universiteit Brussel

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