Projects per year
Personal profile
Expertise
Academic, Pharmaceutical and Pharmacological Sciences,
Expertise
Experimental in vitro toxicology and dermato-cosmetology
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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The Immunological Profile of Adipose Mesenchymal Stromal/Stem Cells after Cell Expansion and Inflammatory Priming
Buyl, K., Merimi, M., Rodrigues, R. M., Rahmani, S., Fayyad-Kazan, M., Bouhtit, F., Boukhatem, N., Vanhaecke, T., Fahmi, H., Kock, J. D. & Najar, M., 15 Jul 2024, In: Biomolecules. 14, 7, 22 p., 852.Research output: Contribution to journal › Article › peer-review
Open Access -
Human skin stem cell-derived hepatic cells as in vitro drug discovery model for insulin-driven de novo lipogenesis
Buyl, K., Vrints, M., Fernando, R., Desmae, T., Van Eeckhoutte, T., Jans, M., Van Der Schueren, J., Boeckmans, J., Rodrigues, R. M., De Boe, V., Rogiers, V., De Kock, J., Beirinckx, F. & Vanhaecke, T., 15 Oct 2023, In: European Journal of Pharmacology. 957, 14 p., 175989.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)104 Downloads (Pure) -
From NAFLD to MAFLD: Aligning translational in vitro research to clinical insights
Gatzios, A., Rombaut, M., Buyl, K., De Kock, J., Rodrigues, R., Rogiers, V., Vanhaecke, T. & Boeckmans, J., 13 Jan 2022, In: Biomedicines. 10, 1, 19 p., 161.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)143 Downloads (Pure) -
Resmetirom reduces lipid load, restores THRB expression and prevents cell damage in a human stem cell based in vitro MAFLD model.
Gatzios, A., Rodrigues, R., De Kock, J., Verhoeven, A., Sepehri, S., Buyl, K., Rombaut, M., Rogiers, V., Boeckmans, J. & Vanhaecke, T., 10 Jun 2022, Resmetirom reduces lipid load, restores THRB expression and prevents cell damage in a human stem cell based in vitro MAFLD model.. 3rd European Fatty Liver Conference, p. 49-49 1 p.Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)
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Resmetirom reduces lipid load, restores THRB expression and prevents cell damage in a human stem cell based in vitro MAFLD model.
Gatzios, A., Rodrigues, R., De Kock, J., Verhoeven, A., Sepehri, S., Buyl, K., Rombaut, M., Rogiers, V., Boeckmans, J. & Vanhaecke, T., 21 Sept 2022.Research output: Unpublished contribution to conference › Poster
Prizes
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Abcam 15 Discoveries contest finalist
Buyl, Karolien (Recipient), 2014
Prize: Prize (including medals and awards)
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INVITROM bursary for ESTIV congress
Buyl, Karolien (Recipient), 7 Apr 2014
Prize: Prize (including medals and awards)
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Wetenschappelijk Fonds Willy Gepts UZ Brussel
Buyl, Karolien (Recipient), 2016
Prize: Prize (including medals and awards)
Activities
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Resmetirom reduces lipid load, restores THRB expression and prevents cell damage in a human stem cell based in vitro MAFLD model.
Alexandra Gatzios (Speaker), Robim Marcelino Rodrigues (Contributor), Joery De Kock (Contributor), Anouk Verhoeven (Contributor), Sara Sepehri (Contributor), Karolien Buyl (Contributor), Matthias Rombaut (Contributor), Vera Rogiers (Contributor), Joost Boeckmans (Contributor) & Tamara Vanhaecke (Contributor)
10 Jun 2022Activity: Talk or presentation › Talk or presentation at a conference
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A human hepatocyte-like cell based In Vitro model for hepatic insulin-driven De Novo Lipogenesis
Karolien Buyl (Speaker), Martine Vrints (Speaker), Ruani Fernando (Speaker), Thomas Van Eeckhoute (Speaker), Mia Jans (Speaker), Joost Boeckmans (Speaker), Robim Marcelino Rodrigues (Speaker), Vera Rogiers (Speaker), Jan Van Der Schueren (Speaker), Joery De Kock (Speaker), Tamara Vanhaecke (Speaker) & Filip Beirinckx (Speaker)
2020 → …Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Application of a human skin stem cell-derived in vitro liver model of non-alcoholic steatohepatitis
Joost Boeckmans (Speaker), Valerie Vandenbempt (Contributor), Karolien Buyl (Contributor), Alessandra Natale (Contributor), Joery De Kock (Contributor), Vera Rogiers (Contributor), Tamara Vanhaecke (Contributor) & Robim Marcelino Rodrigues (Contributor)
16 Oct 2018Activity: Talk or presentation › Talk or presentation at a conference
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Elafibranor reduces the expression of pannexin1 and CCL5 in a human-relevant skin stem cell-based model of non-alcoholic steatohepatitis (NASH)
Joost Boeckmans (Speaker), Alessandra Natale (Contributor), Karolien Buyl (Contributor), Joery De Kock (Contributor), Vera Rogiers (Contributor), Tamara Vanhaecke (Contributor) & Robim Marcelino Rodrigues (Contributor)
20 Mar 2018Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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In vitro modelling of NAFLD using stem cells: state of the art
Joost Boeckmans (Speaker), Alessandra Natale (Contributor), Karolien Buyl (Contributor), Joery De Kock (Contributor), Vera Rogiers (Contributor), Tamara Vanhaecke (Contributor) & Robim Marcelino Rodrigues (Contributor)
22 Mar 2018Activity: Talk or presentation › Talk or presentation at a conference
Thesis
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Bestuderen van de novo lipogenese in menselijke huid-afgeleide stamcellen
Author: Rejdy, M., Vanhaecke, T. & Buyl, K., 2018Supervisor: Vanhaecke, T. (Promotor)
Student thesis: Master's Thesis
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Characterization and reprogramming of umbilical cord-derived mesenchymal stromal cells towards the hepatic lineage
Author: Buyl, K., De Kock, J., Vanhaecke, T., Rogiers, V., De Bundel, D., Hernot, S., Vinken, M., Roskams, T., Najimi, M. & Castell, J., 28 Feb 2017Supervisor: De Kock, J. (Promotor), Vanhaecke, T. (Promotor), Rogiers, V. (Promotor), De Bundel, D. (Jury), Vinken, M. (Jury), Hernot, S. (Jury), Najimi, M. (External person) (Jury), Roskams, T. (External person) (Jury) & Castell, J. V. (External person) (Jury)
Student thesis: Doctoral Thesis