Projects per year
Personal profile
Expertise
Academic, Pharmaceutical and Pharmacological Sciences,
Expertise
Experimental in vitro toxicology and dermato-cosmetology
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Dive into the research topics where Karolien Buyl is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
- 1 Finished
Research output
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From NAFLD to MAFLD: Aligning translational in vitro research to clinical insights
Gatzios, A., Rombaut, M., Buyl, K., De Kock, J., Rodrigues, R., Rogiers, V., Vanhaecke, T. & Boeckmans, J., 13 Jan 2022, In : Biomedicines. 10, 1, 19 p., 161.Research output: Contribution to journal › Article
Open AccessFile29 Downloads (Pure) -
Resmetirom reduces lipid load, restores THRB expression and prevents cell damage in a human stem cell based in vitro MAFLD model.
Gatzios, A., Rodrigues, R., De Kock, J., Verhoeven, A., Sepehri, S., Buyl, K., Rombaut, M., Rogiers, V., Boeckmans, J. & Vanhaecke, T., 10 Jun 2022, Resmetirom reduces lipid load, restores THRB expression and prevents cell damage in a human stem cell based in vitro MAFLD model.. 3rd European Fatty Liver Conference, p. 49-49 1 p.Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)
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Human hepatic in vitro models reveal distinct anti-NASH potencies of PPAR agonists
Boeckmans, J., Natale, A., Rombaut, M., Buyl, K., Cami, B., De Boe, V., Heymans, A., Rogiers, V., De Kock, J., Vanhaecke, T. & Rodrigues, R. M., Apr 2021, In : Cell Biology and Toxicology. 37, 2, p. 293-311 19 p.Research output: Contribution to journal › Article
Open Access7 Citations (Scopus)19 Downloads (Pure) -
Transcriptional Profile of Cytokines, Regulatory Mediators and TLR in Mesenchymal Stromal Cells after Inflammatory Signaling and Cell-Passaging
Merimi, M., Buyl, K., Daassi, D., Rodrigues, R. M., Melki, R., Lewalle, P., Vanhaecke, T., Fahmi, H., Rogiers, V., Lagneaux, L., De Kock, J. & Najar, M., 7 Jul 2021, In : International Journal of Molecular Sciences. 22, 14, 24 p., 7309.Research output: Contribution to journal › Article
Open AccessFile4 Citations (Scopus)47 Downloads (Pure) -
Flow cytometric quantification of neutral lipids in a human skin stem cell-derived model of NASH
Boeckmans, J., Natale, A., Rombaut, M., Buyl, K., Vanhaecke, T., Rogiers, V., Rodrigues, R. M. & De Kock, J., 2020, In : MethodsX. 7, 7 p., 101068.Research output: Contribution to journal › Article
Open AccessFile3 Citations (Scopus)38 Downloads (Pure)
Prizes
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Abcam 15 Discoveries contest finalist
Karolien Buyl (Recipient), 2014
Prize: Prize (including medals and awards)
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INVITROM bursary for ESTIV congress
Karolien Buyl (Recipient), 7 Apr 2014
Prize: Prize (including medals and awards)
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Wetenschappelijk Fonds Willy Gepts UZ Brussel
Karolien Buyl (Recipient), 2016
Prize: Prize (including medals and awards)
Activities
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Resmetirom reduces lipid load, restores THRB expression and prevents cell damage in a human stem cell based in vitro MAFLD model.
Alexandra Gatzios (Speaker), Robim Marcelino Rodrigues (Contributor), Joery De Kock (Contributor), Anouk Verhoeven (Contributor), Sara Sepehri (Contributor), Karolien Buyl (Contributor), Matthias Rombaut (Contributor), Vera Rogiers (Contributor), Joost Boeckmans (Contributor), Tamara Vanhaecke (Contributor)10 Jun 2022Activity: Talk or presentation › Talk or presentation at a conference
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A human hepatocyte-like cell based In Vitro model for hepatic insulin-driven De Novo Lipogenesis
Karolien Buyl (Speaker), Martine Vrints (Speaker), Ruani Fernando (Speaker), Thomas Van Eeckhoute (Speaker), Mia Jans (Speaker), Joost Boeckmans (Speaker), Robim Marcelino Rodrigues (Speaker), Vera Rogiers (Speaker), Jan Van Der Schueren (Speaker), Joery De Kock (Speaker), Tamara Vanhaecke (Speaker), Filip Beirinckx (Speaker)2020 → …Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Application of a human skin stem cell-derived in vitro liver model of non-alcoholic steatohepatitis
Joost Boeckmans (Speaker), Valerie Vandenbempt (Contributor), Karolien Buyl (Contributor), Alessandra Natale (Contributor), Joery De Kock (Contributor), Vera Rogiers (Contributor), Tamara Vanhaecke (Contributor), Robim Marcelino Rodrigues (Contributor)16 Oct 2018Activity: Talk or presentation › Talk or presentation at a conference
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In vitro modelling of NAFLD using stem cells: state of the art
Joost Boeckmans (Speaker), Alessandra Natale (Contributor), Karolien Buyl (Contributor), Joery De Kock (Contributor), Vera Rogiers (Contributor), Tamara Vanhaecke (Contributor), Robim Marcelino Rodrigues (Contributor)22 Mar 2018Activity: Talk or presentation › Talk or presentation at a conference
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Elafibranor reduces the expression of pannexin1 and CCL5 in a human-relevant skin stem cell-based model of non-alcoholic steatohepatitis (NASH)
Joost Boeckmans (Speaker), Alessandra Natale (Contributor), Karolien Buyl (Contributor), Joery De Kock (Contributor), Vera Rogiers (Contributor), Tamara Vanhaecke (Contributor), Robim Marcelino Rodrigues (Contributor)20 Mar 2018Activity: Talk or presentation › Talk or presentation at a workshop/seminar
Thesis
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Bestuderen van de novo lipogenese in menselijke huid-afgeleide stamcellen
Author: Rejdy, M., Vanhaecke, T. & Buyl, K., 2018Student thesis: Master's Thesis
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Characterization and reprogramming of umbilical cord-derived mesenchymal stromal cells towards the hepatic lineage
Author: Buyl, K., De Kock, J., Vanhaecke, T., Rogiers, V., De Bundel, D., Hernot, S., Vinken, M., Roskams, T., Najimi, M. & Castell, J., 28 Feb 2017Supervisor: De Kock, J. (Promotor), Vanhaecke, T. (Promotor), Rogiers, V. (Promotor), De Bundel, D. (Jury), Vinken, M. (Jury), Hernot, S. (Jury), Najimi, M. (External person) (Jury), Roskams, T. (External person) (Jury) & Castell, J. V. (External person) (Jury)
Student thesis: Doctoral Thesis
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Invloed van het cultuurmedium op de expressie van hepatische merkers en transcritpiefactoren in mesenchymale stamcellen afgeleid van de navelstreng
Author: Demoor, H., Vanhaecke, T., Rogiers, V., De Kock, J. & Buyl, K., 2014Supervisor: Vanhaecke, T. (Promotor), Rogiers, V. (Promotor), De Kock, J. (Promotor) & Buyl, K. (Co-promotor)
Student thesis: Master's Thesis
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Karakterisatie van hepatische merkers en transcriptiefactoren in mesenchymale stamcellen afgeleid van de navelstreng.
Author: De Jonghe, P., Vanhaecke, T., Rogiers, V., Buyl, K. & De Kock, J., 2013Supervisor: Vanhaecke, T. (Promotor), Rogiers, V. (Promotor), Buyl, K. (Co-promotor) & De Kock, J. (Co-promotor)
Student thesis: Master's Thesis