Projects per year
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Collaborations and top research areas from the last five years
Projects
- 2 Finished
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FWOSB112: CONVICT: sentencing Cancer cells to death through ONcolytic Virotherapy and modulation of the Immune Checkpoint TIGIT
Zeven, K. (Administrative Promotor) & Devoogdt, N. (Administrative Promotor)
1/11/20 → 31/10/24
Project: Fundamental
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ANI259: CONVICT: sentencing cancer cells to death through ONcolytic Virotherapy and modulation of the Immune Checkpoint TIGIT
Zeven, K. (Administrative Promotor)
1/11/20 → 31/10/21
Project: Fundamental
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Immune modulation following α and β- radionuclide therapy targeting fibroblast activation protein-α in a preclinical tumor model
Ceuppens, H., De Ridder, K., Ertveldt, T., Zeven, K., de Mey, W., Pombo Antunes, A. R., Navarro, L., Dumauthioz, N., Lahoutte, T., Debacker, J., Devoogdt, N., Keyaerts, M., D'Huyvetter, M., Goyvaerts, C. & Breckpot, K., 1 Dec 2025, In: Oncoimmunology. 14, 1, 16 p., 2540054.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)4 Downloads (Pure) -
Novel Resin-Based Recovery of Astatine-211 : A Breakthrough for Efficient Radiolabeling
Navarro, L., Sevenois, M., Ertveldt, T., Zeven, K., Jensen, H. J., Haddad, F., D'Huyvetter, M. & Covens, P., 12 May 2025. 1 p.Research output: Unpublished contribution to conference › Poster
File15 Downloads (Pure) -
Optimizing antibody PET imaging: a comparative preclinical analysis of nanobody and minibody-like PET tracers
Zeven, K., Dierick, H., Sevenois, M., Baudhuin, H. V., Navarro, L., Van den Block, S., Saliën, J., Breckpot, K., Bridoux, J., De Groof, T. & Devoogdt, N., Aug 2025, In: European Journal of Nuclear Medicine and Molecular Imaging. 52, 10, p. 3833-3845 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)5 Downloads (Pure) -
Advancements in Nuclear Imaging Using radiolabeled Nanobody tracers to support Cancer Immunotherapy
Zeven, K., Lauwers, Y., De Mey, L., Debacker, J., De Pauw, T., De Groof, T. & Devoogdt, N., 26 Aug 2024, In: Immunotherapy Advances. 4, 1, 11 p., Itae006.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)68 Downloads (Pure) -
Generation and Characterization of Novel Pan-Cancer Anti-uPAR Fluorescent Nanobodies as Tools for Image-Guided Surgery
Mateusiak, Ł., Floru, S., De Groof, T. W. M., Wouters, J., Declerck, N. B., Debie, P., Janssen, S., Zeven, K., Breckpot, K., Puttemans, J., Vincke, C., Devoogdt, N. & Hernot, S., Aug 2024, In: Advanced Science. 11, 30, 11 p., e2400700.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)88 Downloads (Pure)
Datasets
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Generation and Characterization of Novel Pan-Cancer Anti-uPAR Fluorescent Nanobodies as Tools for Image-Guided Surgery
Mateusiak, L. (Creator), Floru, S. (Researcher), De Groof, T. (Researcher), Wouters, J. (Researcher), Declerck, N. (Researcher), Debie, P. (Researcher), Janssen, S. (Researcher), Zeven, K. (Researcher), Puttemans, J. (Researcher), Vincke, C. (Researcher), Breckpot, K. (Project Member), Devoogdt, N. (Project Member) & Hernot, S. (Supervisor), Zenodo, 26 Mar 2025
DOI: https://zenodo.org/records/15089920
Dataset
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Dataset of Development and evaluation of nanobody tracers for noninvasive nuclear imaging of the immune-checkpoint TIGIT
De Groof, T. (Creator), Zeven, K. (Creator), Ceuppens, H. (Creator), Awad, R. M. (Creator), Ertveldt, T. (Creator), de Mey, W. (Creator), Meeus, F. (Creator), Raes, G. (Creator), Breckpot, K. (Creator) & Devoogdt, N. (Creator), Zenodo, 24 Mar 2025
Dataset
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Dataset of Optimizing antibody PET imaging: a comparative preclinical analysis of nanobody and minibody-like PET tracers
Zeven, K. (Creator), Dierick, H. (Creator), Sevenois, M. (Creator), Baudhuin, H. V. (Creator), Navarro, L. (Creator), Van den Block, S. (Creator), Saliën, J. (Creator), Breckpot, K. (Creator), Bridoux, J. (Creator), De Groof, T. (Creator) & Devoogdt, N. (Creator), Zenodo, 31 Mar 2025
Dataset
Prizes
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Development of a radiotracer and small protein inhibitor against the novel immune checkpoint TIGIT
Zeven, K. (Recipient), Devoogdt, N. (Recipient) & Breckpot, K. (Recipient), 15 Dec 2020
Prize: Fellowship awarded competitively
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Fully automated production of [18F]FB-labeled single-domain antibodies: the immune-checkpoint TIGIT for PET imaging
Dierick, H. (Speaker), Zeven, K. (Contributor), Navarro, L. (Contributor), Lahoutte, T. (Contributor), Devoogdt, N. (Contributor), Caveliers, V. (Contributor) & Bridoux, J. (Contributor)
18 Apr 2024 → 21 Apr 2024Activity: Talk or presentation › Talk or presentation at a conference
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Evaluation of nanobody-scaffolds as nuclear imaging tracers for noninvasive detection of the next generation immune checkpoint TIGIT
Zeven, K. (Speaker), Dierick, H. (Contributor), Sevenois, M. (Contributor), Baudhuin, H. V. (Contributor), Bridoux, J. (Contributor), Navarro, L. (Contributor), De Groof, T. (Contributor), Raes, G. (Contributor), Breckpot, K. (Contributor) & Devoogdt, N. (Contributor)
26 Aug 2024 → 30 Aug 2024Activity: Talk or presentation › Talk or presentation at a conference
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In vivo optical imaging of glioma using a novel uPAR-targeting fluorescent single-domain antibody
Mateusiak, L. (Speaker), Floru, S. (Contributor), De Groof, T. (Contributor), Declerck, N. (Contributor), Wouters, J. (Contributor), Janssen, S. (Contributor), Debie, P. (Contributor), Zeven, K. (Contributor), Vincke, C. (Contributor), Puttemans, J. (Contributor), Stroet, M. (Contributor), Breckpot, K. (Contributor), Devoogdt, N. (Contributor) & Hernot, S. (Contributor)
16 Mar 2023Activity: Talk or presentation › Talk or presentation at a conference
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The development of radiolabeled nanobodies against the next-generation immune checkpoint TIGIT for non-invasive immune phenotyping of tumors
Zeven, K. (Speaker), De Groof, T. (Contributor), Awad, R. M. (Contributor), De Mey, W. (Contributor), Ertveldt, T. (Contributor), Ceuppens, H. (Contributor), De Jonghe, K. (Contributor), Raes, G. (Contributor), Keyaerts, M. (Contributor), Breckpot, K. (Contributor) & Devoogdt, N. (Contributor)
16 Mar 2023Activity: Talk or presentation › Talk or presentation at a conference
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In vivo optical imaging using a novel fluorescently-labeled single-domain antibody targeting a universal tumor marker
Mateusiak, L. (Speaker), Floru, S. (Contributor), Wouters, J. (Contributor), De Groof, T. (Contributor), Declerck, N. (Contributor), Janssen, S. (Contributor), Debie, P. (Contributor), Zeven, K. (Contributor), Puttemans, J. (Contributor), Breckpot, K. (Contributor), Devoogdt, N. (Contributor) & Hernot, S. (Contributor)
28 Jan 2023Activity: Talk or presentation › Talk or presentation at a conference
Thesis
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Evaluation of single domain antibodies against the immune checkpoint LAG-3 for noninvasive nuclear imaging and therapy of cancer
Devoogdt, N. (Promotor), Zeven, K. ((PhD) Student) & Breckpot, K. (Co-promotor), Lecocq, Q. (Promotor), 20 Jun 2019Student thesis: Master's Thesis
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Targeting the novel immune checkpoint TIGIT using single domain antibodies for imaging and therapy
Devoogdt, N. (Promotor), Breckpot, K. (Promotor), Keyaerts, M. (Promotor) & Zeven, K. ((PhD) Student), 27 Nov 2024Student thesis: Doctoral Thesis