Projects per year
Personal profile
Expertise
I'm a scientific researcher with a biomedical background. I have developed a broad interest and
knowledge in the (patho)biology and development of diseases and cancer. I am currently involved in the molecular and genetic profiling of solid and hematological cancers, both in diagnostic and research setting. During my past projects, I was involved in concept designing, coordinating projects, designing and conducting scientific experiments. I gained experience in a wide variety of cellular and molecular assays to address cellular, biochemical and molecular processes and drug-related mechanisms. I also gained experience in bio-informatics including analysis of microarray and next-generation sequencing.
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Collaborations and top research areas from the last five years
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Projects
- 6 Finished
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FWOKN311: Epigenetic-targeted treatment in multipel myeloma: Identification of new combination strategies focusing on DNA repair and immunotherapy.
Maes, K. (Administrative Promotor)
1/01/19 → 31/12/19
Project: Fundamental
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AIIFUND40: Junior Grant Award Agreement: Unraveling the balance of tolerance and immunogenicity of multiple myeloma cells.
Maes, K. (Administrative Promotor)
1/01/19 → 31/12/19
Project: Fundamental
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FWOTM900: Modulating epigenetic mechanisms to enhance cancer immunotherapy.
Breckpot, K. (Administrative Promotor), De Beck, L. (Mandate) & Maes, K. (Co-Promotor)
1/10/18 → 30/09/22
Project: Fundamental
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FWOKN285: Study of the immune-modulating effects of epigenetically targeted treatments in multiple myeloma
Maes, K. (Administrative Promotor) & Vanderkerken, K. (Co-Promotor)
1/01/17 → 31/12/17
Project: Fundamental
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AIIFUND7: Onderzoek naar de immunomodulerende eigenschappen van epigenetisch gerichte behandelingen in multipel myeloom.
Vanderkerken, K. (Administrative Promotor) & Maes, K. (Co-Promotor)
5/07/16 → 5/07/20
Project: Fundamental
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Beyond BRAF V600E: Revealing the Hidden Clinical Relevance of Uncharacterized BRAF Variants
Vanisterbecq, D., Vandenplas, H., Olsen, C., Vlaeminck, J., Vaeyens, F., Helsen, C., Hes, F. J., Giron, P. & Maes, K., 11 Jun 2025, In: Molecular Oncology. 19, S1, p. 318-319 2 p., EACR25-1892.Research output: Contribution to journal › Meeting abstract (Journal)
Open Access -
Beyond BRAFV600E - Revealing the Hidden Clinical Relevance of Uncharacterized BRAF Variants
Vanisterbecq, D., Vandenplas, H., Olsen, C., Vlaeminck, J., Vaeyens, F., Helsen, C., Hes, F. J., Giron, P. & Maes, K., 17 Jun 2025, (Unpublished). 1 p.Research output: Unpublished contribution to conference › Poster
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Beyond Known Driver Variants - Unraveling variants of unknown significance in BRAF: A path to improve diagnosis, prognosis, and therapy in cancer patients
Vanisterbecq, D., Vandenplas, H., Olsen, C., Vlaeminck, J., Vaeyens, F., Helsen, C., Hes, F. J., Giron, P. & Maes, K., 14 Mar 2025, (Unpublished). 1 p.Research output: Unpublished contribution to conference › Poster
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PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism
Oudaert, I., van den Broecke, L., Aksoy, O., Lind, J., Vallet, S., Van der Vreken, A., Ates, G., Massie, A., Maes, K., De Veirman, K., De Bruyne, E., Vanderkerken, K., Podar, K. & Menu, E., 11 Sept 2025, In: Molecular Oncology. 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Unraveling variants of unknown significance in BRAF: A path to improve diagnosis, prognosis, and therapy in cancer patients
Vanisterbecq, D., Vandenplas, H., Olsen, C., Vlaeminck, J., Vaeyens, F., Helsen, C., Hes, F. J., Giron, P. & Maes, K., 2025, (Unpublished).Research output: Unpublished contribution to conference › Poster
Datasets
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RNA sequencing dataset of tasquinimod-treated LP1 cells
Maes, K. (Creator) & De Veirman, K. (Creator), ArrayExpress, 25 Jan 2023
Dataset
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Targeting S100A9 protein affects mTOR-ER stress signaling and increases venetoclax sensitivity in Acute Myeloid Leukemia
De Veirman, K. (Creator) & Maes, K. (Creator), ArrayExpress, 1 Dec 2023
DOI: https://www.ebi.ac.uk/biostudies/arrayexpress/studies/E-MTAB-13095, https://www.ebi.ac.uk/biostudies/arrayexpress/studies/E-MTAB-13095
Dataset
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PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism
Menu, E. (Creator), Oudaert, I. (Creator), Vanderkerken, K. (Creator), De Veirman, K. (Creator), De Bruyne, E. (Creator), Van der Vreken, A. (Creator), Ates, G. (Creator), Massie, A. (Creator) & Maes, K. (Creator), DRYAD, 6 Nov 2025
Dataset
Prizes
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Clarifying the functional effect of genetic variants of unknown significance for improved patient therapy
Maes, K. (Recipient), 2022
Prize: Other distinction
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Unravelling DNA variants of unknown significance: towards further diagnosis, prognosis, and targeted therapies in cancer patients
Maes, K. (Recipient) & Vanisterbecq, D. (Recipient), Mar 2024
Prize: Other distinction
Activities
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1st Belgian cfDNA Oncology Meeting 2024
Vlaeminck, J. (Participant), Maes, K. (Participant), Vaeyens, F. (Participant) & Helsen, C. (Participant)
7 Nov 2024Activity: Participating in or organising an event › Participation in conference
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Afscheidssymposium Prof. dr. Thomy de Ravel "Les Beaux Arts van Genetica"
Hes, F. J. (Chair), Giron, P. (Chair), Vanden Eynde, N. E. M. (Participant), Bansagi, B. K. (Participant), Belva, F. (Participant), Buysse, A. (Participant), De Becker, P. (Participant), De Schutter, E. (Participant), De Smedt, D. (Participant), Delle Chiaie, B. (Participant), Dequeker, B. (Participant), Dimitrov, B. (Participant), Helsen, C. (Participant), Maes, K. (Participant), Mertens, J. (Participant), Polsler, L. (Participant), Bonduelle, M.-L. (Participant), Meerschaut, I. (Participant), Van Steirteghem, A. (Participant), Weytjens, C. (Participant), Rijckmans, E. (Participant), Sammels, E. (Participant), Scheirlynck, E. (Participant), Vaeyens, F. (Participant), Van Berkel, K. (Participant), Van Den Bogaert, A. (Participant), Van de Voorde, S. R. (Participant), Vanderstraeten, V. (Participant), Vantroys, E. (Participant), Verdyck, P. (Participant), Vlaeminck, J. (Participant) & Winter, C. (Participant)
24 Oct 2024Activity: Participating in or organising an event › Participation in conference
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Characterization of the evolving mutational landscape in multiple myeloma during disease progression using blood-derived cell free DNA: an explorative study
Heestermans, R. (Speaker), De Brouwer, W. (Contributor), Maes, K. (Contributor), Vande Broek, I. (Contributor), Vaeyens, F. (Contributor), Olsen, C. (Contributor), Janssen, T. (Contributor), De Becker, A. (Contributor), Bakkus, M. (Contributor), Schots, H. (Contributor) & Van Riet, I. (Contributor)
3 Feb 2023Activity: Talk or presentation › Talk or presentation at a conference
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Molecular biology and cytometry course
Maes, K. (Speaker)
12 May 2022 → 13 May 2022Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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40 years of Medical Genetics at UZ Brussel
Hes, F. J. (Organiser), De Grève, J. (Member of programme committee), Keymolen, K. (Member of programme committee), Hutse, V. (Member of programme committee), Cuevas Y Bretones, M. F. (Member of programme committee), Dequeker, B. (Member of programme committee), Giron, P. (Member of programme committee), Stouffs, K. (Member of programme committee), Maes, K. (Member of programme committee), Vlaeminck, J. (Member of programme committee), Van de Voorde, S. R. (Host), Van Der Kelen, A. (Host), Uyttebroeck, S. (Chair) & De Rycke, M. (Chair)
1 Oct 2022Activity: Participating in or organising an event › Participation in conference
Thesis
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Characterization of hepcidin-inducing cytokines in multiple myeloma.
Maes, K. ((PhD) Student), Vanderkerken, K. (Promotor), Van Grunsven, L. (Jury), Van Den Branden, C. (Jury) & Kooijman, R. (Jury), Vanderkerken, K. (Promotor), Van Grunsven, L. A. (Jury), Van Den Branden, C. (Jury) & Kooijman, R. (Jury), 28 Jan 2010Student thesis: Master's Thesis
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Characterizing variants of unknown significance in the MET proto-oncogene and intron-exon boundaries for improved management of genetic disorders.
Vela I Artizà, J. ((PhD) Student), Maes, K. (Promotor), Vlaeminck, J. (Co-promotor), Giron, P. (Co-promotor) & Vanisterbecq, D. (Advisor), 2025Student thesis: Master's Thesis
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VEGF-A, a trigger for de novo beta cell formation
Maes, K. ((PhD) Student), Heimberg, H. (Promotor) & De Leu, N. (Advisor), 2009Student thesis: Master's Thesis