Projects per year
Personal profile
Expertise
- Fundamental Research in Eukaryotic Gene Expression. Protein Structure and Action (X-ray crystallography). Protein engineering (Site directed mutagenesis/Enzym kinetics).
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- 6 Similar Profiles
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CONO272: Study day on synchrotron and neutron radiation DD. 23 april 2009.
20/02/09 → …
Project: Fundamental
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AIIESA11: PRODEX 8 : Influence of mass transport and surface growth processes on protein crystal perfection.+ PRODEX 9, PRODEX10.
1/01/06 → 31/12/25
Project: Fundamental
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Research output
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Epitope tag for affinity-based applications
Pardon, E., Steyaert, J. & Wyns, L., 18 Oct 2018, IPC No. C07K14/47, C07K5/10, EPO, Patent No. EP2576609B, 25 May 2011, Priority date 25 May 2010, Priority No. GB1008682.5Research output: Patent
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Epitope tag for affinity-based applications
Steyaert, J., Pardon, E. & Wyns, L., 2016, Patent No. US9518084Research output: Patent
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Study of the structural and dynamic effects in the FimH adhesin upon α-D-heptyl mannose binding
Vanwetswinkel, S., Volkov, A. N., Sterckx, Y., Garcia Pino, A., Buts, L., Vranken, W., Bouckaert, J., Roy, R., Wyns, L. & Van Nuland, N., 29 Jan 2014, In: Journal of Medicinal Chemistry. 57, p. 1416-1427 12 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus) -
A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.
De Genst, E., Chan, P., Pardon, E., Hsu, S-T. D., Kumita, J., Christodoulou, J., Menzer, L., Dimitri, C., Robinson, C. V., Muyldermans, S., Matagne, A., Wyns, L., Dobson, C. M. & Dumoulin, M., 6 Aug 2013, In: Journal of Physical Chemistry B. Special Issue:Peter G. Wolynes Festschrift, p. 13245-13258 14 p.Research output: Contribution to journal › Article › peer-review
40 Citations (Scopus) -
Nanobodies Raised against Monomeric alpha-Synuclein Distinguish between Fibrils at Different Maturation Stages
Guilliams, T., El-Turk, F., Buell, A. K., O'Day, E. M., Aprile, F. A., Esbjoerner, E. K., Vendruscolo, M., Cremades, N., Pardon, E., Wyns, L., Welland, M. E., Steyaert, J., Christodoulou, J., Dobson, C. M. & De Genst, E., 24 Jul 2013, In: Journal of Molecular Biology. 425, 14, p. 2397-2411 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile85 Citations (Scopus)204 Downloads (Pure)
Prizes
Activities
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23rd Solvay Conference on Chemistry: new chemistry and new opportunities from the expanding protein universe
Lode Wyns (Keynote speaker)
16 Oct 2013 → 20 Oct 2013Activity: Talk or presentation › Talk or presentation at a conference
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Solvay workshop on "Design Principles and hardware of biological circuits"
Lode Wyns (Organiser)
15 Feb 2012 → 17 Feb 2012Activity: Participating in or organising an event › Participation in workshop, seminar
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Discussion day "Large European Infrastructures"
Lode Wyns (Organiser)
Feb 2007Activity: Participating in or organising an event › Participation in conference
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University of Southern Denmark (External organisation)
Lode Wyns (Member)
1 Jan 2007 → …Activity: Membership › Membership of external research organisation
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The 17th Joint meeting, Glycobiology-Glycosciences
Lode Wyns (Organiser)
5 Nov 2006 → 7 Nov 2006Activity: Participating in or organising an event › Participation in conference