Research output per year
Research output per year
Personal profile
Expertise
Research focus: mRNA technology, development and manufacturing of mRNA-based therapeutics.
- Improving stability and biological activity of mRNA vaccines;
- Individualised Neoantigen-based cancer therapy;
- Automatised mRNA production pipeline for research grade/ GMP
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Dive into the research topics where Lorenzo Franceschini is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Alpha-galactosylceramide improves the potency of mRNA LNP vaccines against cancer and intracellular bacteria
Meulewaeter, S., Aernout, I., Deprez, J., Engelen, Y., De Velder, M., Franceschini, L., Breckpot, K., Van Calenbergh, S., Asselman, C., Boucher, K., Impens, F., De Smedt, S. C., Verbeke, R. & Lentacker, I., Jun 2024, In: Journal of Controlled Release. 370, p. 379-391 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)1 Downloads (Pure) -
Cap-to-Tail Analysis of HLA-I antigen encoding mRNA
Esprit, A., Autaers, D., Breckpot, K. & Franceschini, L., 24 Jan 2024, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Modulating the immune response to SARS-CoV-2 by different nanocarriers delivering an mRNA expressing trimeric RBD of the spike protein: COVARNA Consortium
Franceschini, L., Mar 2024, In: NPJ vaccines. 15 p., 53.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
An mRNA mix redirects dendritic cells towards an antiviral program, inducing anticancer cytotoxic stem cell and central memory CD8+ T cells
de Mey, W., Locy, H., De Ridder, K., De Schrijver, P., Autaers, D., Lakdimi, A., Esprit, A., Franceschini, L., Thielemans, K., Verdonck, M. & Breckpot, K., 4 Mar 2023, In: Frontiers in Immunology. 14, 10 p., 1111523.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)36 Downloads (Pure) -
Assessment of Human SARS CoV-2-Specific T-Cell Responses Elicited In Vitro by New Computationally Designed mRNA Immunogens: COVARNA
Esteban, I., Pastor-Quinones, C., Usero, L., Aurrecoechea, E., Franceschini, L., Esprit, A., Gelpi, J. L., Martinez-Jimenez, F., Lopez-Biga, N., Breckpot, K., Thielemans, K., Leal, L., Gomez, C. E., Sistere-Oro, M., Meyerhans, A., Esteban, M., Alonso, M. J., Garcia, F. & Plana, M., 22 Dec 2023, In: Vaccines. 12, 1, p. 15-30 16 p., 15.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure)
Thesis
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Plasmid engineering to enhance stability and translatability for MRNA-based immunotherapy
Author: Cappelle, C. A., Thielemans, K. & Franceschini, L., 2019Student thesis: Master's Thesis