Projects per year
Personal profile
Expertise
- In vitro and in vivo models to induce islet regeneration or islet cell neogenesis and in which the effect of soluble growth factors, hormones, cytokines or pharmacological substances can be studied
- Regenerative medicine for diabetes
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Dive into the research topics where Luc Bouwens is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
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OZR3588: Financiering FWO hercules: ERA platform: Extended RNA Analysis platform - version 2.0
Rooman, I., Bouwens, L., Heimberg, H., Neyns, B., Vranken, W., Vanhaecke, T., Massie, A., van Grunsven, L., De Bruyne, E., De Bundel, D., Forsyth, R., Breckpot, K., Van Dooren, S., De Kock, J., Njemini, R. & Laoui, D.
1/05/20 → 30/04/24
Project: Fundamental
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HERC44: FWO Hercules MZW: ERA platform: Extended RNA Analysis platform
Rooman, I., Baeyens, L., Goossens, E., Vanhaecke, T., van Grunsven, L., Bouwens, L., De Bundel, D., Bautmans, I., Massie, A., Van Riet, I., De Bruyne, E., De Kock, J. & Forsyth, R.
1/05/18 → 30/04/22
Project: Fundamental
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BRGIMP11: BRIDGE: Diatype : Personalized medicine in diabetes: towards an etiology-based diagnosis and better patient care
1/01/18 → 31/12/21
Project: Applied
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AII62: Transdifferentiation on human exocrine acinar cells to endocrine beta cells by STAT3 and MAPK signalling.
1/07/10 → …
Project: Fundamental
Research output
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Dynamic regulation of expression of KRAS and its effectors determines the ability to initiate tumorigenesis in pancreatic acinar cells
Assi, M., Achouri, Y., Loriot, A., Dauguet, N., Dahou, H., Baldan, J., Libert, M., Fain, J. S., Guerra, C., Bouwens, L., Barbacid, M., Lemaigre, F. P. & Jacquemin, P., 18 Feb 2021, In : Cancer Research.Research output: Contribution to journal › Article
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Peroxiredoxin-I sustains inflammation during pancreatitis
Buckens, H., Pirenne, S., Achouri, Y., Baldan, J., Dahou, H., Bouwens, L., Lemaigre, F. P., Jacquemin, P. & Assi, M., 1 Apr 2021, In : Cellular and molecular gastroenterology and hepatology.Research output: Contribution to journal › Article
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Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization
Antunes, A. R. P., Scheyltjens, I., Lodi, F., Messiaen, J., Antoranz, A., Duerinck, J., Kancheva, D., Martens, L., Vlaminck, K. D., Hove, H. V., Hansen, S. S. K., Bosisio, F. M., Borght, K. V. D., Vleeschouwer, S. D., Sciot, R., Bouwens, L., Verfaillie, M., Vandamme, N., Vandenbroucke, R. E., Wever, O. D. & 8 others, , 29 Mar 2021, In : Nature Neuroscience. 24, p. 595–610 16 p.Research output: Contribution to journal › Article
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Aspalathin Protects Insulin-Producing β Cells against Glucotoxicity and Oxidative Stress-Induced Cell Death
Moens, C., Bensellam, M., Himpe, E., Muller, C. J. F., Jonas, J-C. & Bouwens, L., 12 Feb 2020, In : Molecular Nutrition & Food Research. 64, 8, 1901009.Research output: Contribution to journal › Article
5 Citations (Scopus) -
Inflammation enables pancreatic acinar cells to overcome resistance to oncogenic Kras by increasing its expression and plasma membrane localization.
Assi, M. N., Lodewyckx, J-N., Achouri, Y., Gerard, C., Dauguet, N., Houbracken, I., Heremans, Y., Tyteca, D., Rooman, I., Bouwens, L., Lemaigre, F. & Jacquemin, P., May 2020, In : MOLECULAR CANCER RESEARCH. 18, 5, p. 36-36Research output: Contribution to journal › Meeting abstract (Journal)
Activities
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Acinar cells in the neonatal pancreas grow by self-duplication and not by neogenesis from duct cells
Isabelle Houbracken (Speaker), Luc Bouwens (Contributor)6 Oct 2018Activity: Talk or presentation › Talk or presentation at a conference
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DPP6 as a new biomarker suitable for human islet in vivo imaging
Nick Devoogdt (Contributor), Rita Sofia Garcia Ribeiro (Speaker), Stéphane Demine (Contributor), Julie Kerr-Conte (Contributor), Julien Thévenet (Contributor), Alexander Balhuizen (Contributor), Davide Pacetti (Contributor), Raphael Scharfmann (Contributor), Piero Marchetti (Contributor), Serge Goldman (Contributor), Tony Lahoutte (Contributor), Luc Bouwens (Contributor), Decio Eizirik (Contributor)4 Jun 2018Activity: Talk or presentation › Talk or presentation at a conference
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DPP6 as a new biomarker suitable for human islet in vivo imaging
Rita Sofia Garcia Ribeiro (Speaker), Stephane Demine (Contributor), Julie Kerr-Conte (Contributor), Francois Pattou (Contributor), Davide Pacitte (Contributor), Raphael Scharfmann (Contributor), Piero Marchetti (Contributor), Serge Goldman (Contributor), Tony Lahoutte (Contributor), Luc Bouwens (Contributor), Decio Eizirik (Contributor), Nick Devoogdt (Contributor)4 Oct 2018Activity: Talk or presentation › Talk or presentation at a conference
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A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic islets
Alexander Balhuizen (Contributor), Iris Mathijs (Contributor), Sam Massa (Contributor), Jean-Valery Turatsinze (Contributor), Jens De Vos (Contributor), Stéphane Demine (Contributor), Catarina Xavier (Contributor), Olatz Villate (Contributor), Isabelle Millard (Contributor), Dominique Egrise (Contributor), Carmen Capito (Contributor), Raphael Scharfmann (Contributor), Peter In't Veld (Contributor), Piero Marchetti (Contributor), Serge Muyldermans (Contributor), Serge Goldman (Contributor), Tony Lahoutte (Contributor), Luc Bouwens (Contributor), Decio Eizirik (Contributor), Nick Devoogdt (Speaker)5 Apr 2017 → 7 Apr 2017Activity: Talk or presentation › Talk or presentation at a conference
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A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic islets
Alexander Balhuizen (Contributor), Iris Mathijs (Contributor), Sam Massa (Contributor), Jean-Valery Turatsinze (Contributor), Jens De Vos (Contributor), Stéphane Demine (Contributor), Catarina Xavier (Contributor), Olatz Villate (Contributor), Isabelle Millard (Contributor), Dominique Egrise (Contributor), Carmen Capito (Contributor), Raphael Scharfmann (Contributor), Peter In't Veld (Contributor), Piero Marchetti (Contributor), Serge Muyldermans (Contributor), Serge Goldman (Contributor), Tony Lahoutte (Contributor), Luc Bouwens (Contributor), Decio Eizirik (Contributor), Nick Devoogdt (Speaker)13 Sep 2017 → 16 Sep 2017Activity: Talk or presentation › Talk or presentation at a conference
Thesis
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Assessment of Functional Beta Cell Mass in the Rodent Pancreas
Author: Chintinne, M., Pipeleers, D., Marichal, M., Ling, Z., Van Schravendijk, C., Lahoutte, T., Bouwens, L., Lenmark, A. & Roels, F., 7 Sep 2012Supervisor: Pipeleers, D. (Promotor), Marichal, M. (Co-promotor), Ling, Z. (Co-promotor), Van Schravendijk, C. (Jury), Lahoutte, T. (Jury), Bouwens, L. (Jury), Lernmark, A. (External person) (Jury) & Roels, F. (External person) (Jury)
Student thesis: Doctoral Thesis
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Characterisation of ciliary neurotrophic factor and ciliary neurotrophic factor receptor expression in adult rat pancreas
Author: Desimmie, B., Jun 2008Supervisor: Houbracken, I. (Co-promotor) & Bouwens, L. (Promotor)
Student thesis: Master's Thesis
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De rol van neogenine in de morfogenese en regeneratie van de pancreas.
Author: De Breuck, S. & Bouwens, L., 2001Supervisor: Bouwens, L. (Promotor)
Student thesis: Master's Thesis
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Determining the effects of Aspalathin on INS-1E cells using in vitro experiments: Master thesis of Science in Molecular Biology (Interuniversity Program Molecular Biology)
Author: Fualefac, A., Aug 2016Supervisor: Bouwens, L. (Promotor), Himpe, E. (Co-promotor) & Houbracken, I. (Jury)
Student thesis: Master's Thesis
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Evaluation of antioxidants and flavonoids as beta-cell protectants
Author: Moens, C. & Rosseel, F., 2020Supervisor: Bouwens, L. (Promotor)
Student thesis: Master's Thesis