Projects per year
Personal profile
Expertise
Marius Regin graduated in Biomedical Sciences at the VUB in june 2018 with great distinction. During his master thesis at REGE he validated and implemented simultaneous genomic and transcriptomic sequencing of single human embryonic stem cells. Immediately after obtaining his master degree he started his PhD project under supervision of Prof. Sermon and Prof. Spits on the search for the origin of chromosomal abnormalities in human preimplantation embryos. Furthermore, he has ongoing collaborations with the KU Leuven and the Karolinska Institutet (Sweden).
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Collaborations and top research areas from the last five years
Projects
- 1 Finished
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FWOTM968: The search for the origin of chromosomal abnormalities in human preimplantation embryos
Sermon, K., Spits, C. & Regin, M.
1/10/19 → 31/10/23
Project: Fundamental
Research output
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Children born after assisted reproduction more commonly carry a mitochondrial genotype associating with low birthweight
Spits, C., Mertens, J., Belva, F., van Montfoort, A. PA., Regin, M., Zambelli, F., Seneca, S., Couvreu De Deckersberg, E., Bonduelle, M-L., Tournaye, H., Stouffs, K., Barbé, K., Smeets, B., Van De Velde, H., Sermon, K. & Blockeel, C., 9 Feb 2024, In: Nature Communications. 15, 1, 16 p., 1232 .Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)6 Downloads (Pure) -
De Novo Cancer Mutations Frequently Associate with Recurrent Chromosomal Abnormalities during Long-Term Human Pluripotent Stem Cell Culture
Delbany, D. A., Ghosh, M. S., Krivec, N., Huyghebaert, A., Regin, M., Duong, M. C., Lei, Y., Sermon, K., Olsen, C. & Spits, C., 21 Aug 2024, In: Cells. 13, 16, 12 p., 1395.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity
Krivec, N., Couvreu De Deckersberg, E., Lei, Y., Al Delbany, D., Regin, M., Verhulst, S., van Grunsven, L. A., Sermon, K. & Spits, C., 21 Nov 2024, In: Cell Death and Disease. 15, 14 p., 852.Research output: Contribution to journal › Article › peer-review
Open Access -
Regulators of cell fate decisions in human pre-implantation embryos
Regin, M., 2024, Crazy Copy Center Productions. 195 p.Research output: Thesis › PhD Thesis
Open AccessFile289 Downloads (Pure) -
SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss
Spits, C., Lei, Y., Al Delbany, D., Krivec, N., Regin, M., Couvreu De Deckersberg, E., Janssens, C., Ghosh, M. & Sermon, K., 9 Apr 2024, In: Stem Cell Reports. 19, 4, p. 562-578 17 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus)
Datasets
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De Novo Cancer Mutations Frequently Associate with Recurrent Chromosomal Abnormalities during Long-Term Human Pluripotent Stem Cell Culture
Al Delbany, D. (Creator), Ghosh, M. (Creator), Krivec, N. (Creator), Huyghebaert, A. (Creator), Regin, M. (Creator), Duong, C. M. (Creator), Lei, Y. (Creator), Sermon, K. (Creator), Olsen, C. (Creator) & Spits, C. (Creator), OSF, 2024
Dataset
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Lineage segregation in human pre-implantation embryos is specified by YAP1 and TEAD1
Spits, C. (Creator), Verloes, A. (Creator), Regin, M. (Creator) & Van De Velde, H. (Creator), OSF, 11 Dec 2024
DOI: 10.17605/OSF.IO/NUHZM, https://osf.io/nuhzm/
Dataset
Activities
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Regulators of cell fate decisions in human pre-implantation embryos (Event)
Luc Leyns (Jury), Marius Regin (Presenter), Karen Sermon (Supervisor) & Claudia Spits (Supervisor)
28 Mar 2024Activity: Membership › Member of PhD committee
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Aneuploidy induces proteotoxic stress and autophagy-mediated apoptosis in human preimplantation embryos
Marius Regin (Speaker), Edouard Couvreu De Deckersberg (Contributor), Yves Guns (Contributor), Pieter Verdyck (Contributor), Greta Verheyen (Contributor), Hilde Van De Velde (Contributor), Claudia Spits (Contributor) & Karen Sermon (Contributor)
1 Jul 2021Activity: Talk or presentation › Talk or presentation at a conference
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Mitochondrial DNA mosaicism in early human development
Joke Mertens (Speaker), Marius Regin (Contributor), Neelke De Munck (Contributor), Edouard Couvreu De Deckersberg (Contributor), Christophe Blockeel (Contributor), Herman Tournaye (Contributor), Hilde Van De Velde (Contributor), Karen Sermon (Contributor) & Claudia Spits (Contributor)
17 Sep 2021Activity: Talk or presentation › Talk or presentation at a conference
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Aneuploidy induces proteotoxic stress and autophagy-mediated apoptosis in human preimplantation embryos
Marius Regin (Speaker), Yingnan Lei (Contributor), Edouard Couvreu De Deckersberg (Contributor), Yves Guns (Contributor), Pieter Verdyck (Contributor), Greta Verheyen (Contributor), Hilde Van De Velde (Contributor), Claudia Spits (Contributor) & Karen Sermon (Contributor)
26 Nov 2021 → 27 Nov 2021Activity: Talk or presentation › Talk or presentation at a conference
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Genomics and Embryo Selection in Assisted Reproduction
Marius Regin (Participant)
12 Sep 2019 → 14 Sep 2019Activity: Participating in or organising an event › Participation in workshop, seminar