Projects per year
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Dive into the research topics where Mark Van De Casteele is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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FWOTBM21: TBM Project PRediction Of Type 1 Diabetes Evolution (PROT1DE): Improving early diagnosis using advanced modelling
Barbé, K. (Administrative Promotor), Van De Casteele, M. (CoI (Co-Promotor)), Balti Vounsia, E. (CoI (Co-Promotor)) & Keymeulen, B. (CoI (Co-Promotor))
1/01/26 → 31/12/29
Project: Applied
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FWOAL697: The Neurogenin 3 cell as a guide for cell therapy in diabetes.
Heimberg, H. (Administrative Promotor) & Van De Casteele, M. (Co-Promotor)
1/01/13 → 31/12/16
Project: Fundamental
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IWT383: Research on physiological turnover by replication for expansion of the progenitor betacelmassa in vitro.
Van De Casteele, M. (Administrative Promotor) & Grouwels, G. (Mandate)
1/01/08 → 31/12/11
Project: Fundamental
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ADSI97: CIHR-Fellowship for Simon Amadeus HINKE
Hinke, S. (Co-Promotor), Van De Casteele, M. (Administrative Promotor) & Pipeleers, D. (Co-Promotor)
1/04/05 → 31/03/07
Project: Fundamental
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FWOAL311: Protection of beta cells through control of AMPK mediated processes
Van De Casteele, M. (PI (Promotor, Principal Investigator))
1/01/05 → 31/12/08
Project: Fundamental
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Chemogenetic astrocyte modulation reduces spontaneous hippocampal discharges and metabolite changes in an epilepsy mouse model
Nestor, L., Van Den Herrewegen, Y., Dyer, M., Bossuyt, J., Hendrix, E., Buckinx, A., Bournons, S., Viaene, J., Vander Heyden, Y., Van de Casteele, M., Van Eeckhaut, A., Smolders, I. & De Bundel, D., Feb 2026, In: Epilepsia. 67, 2, p. 934-949 16 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Non-HLA risk loci ERBB3/IKZF4 and ERBB2/IKZF3/GSDMB/ORMDL3 interact to influence progression of autoimmunity in relatives of T1D patients
Mertens, I. M., Keymeulen, B., Gorus, F. K., Van De Casteele, M. & Belgian Diabetes Registry, Mar 2026, In: Diabetes/Metabolism Research and Reviews. 42, 3, 9 p., e70145.Research output: Contribution to journal › Article › peer-review
Open Access -
Analyzing Random Forest’s predictive capability for Type 1 Diabetes progression
Cleymans, N. F., Van De Casteele, M., Vandewalle, J., Desouter, A. K., Gorus, F. K. & Barbe, K., 17 Mar 2025, In: IEEE Open Journal of Instrumentation and Measurement. 4, 11 p., 1000211.Research output: Contribution to journal › Article › peer-review
Open AccessFile124 Downloads (Pure) -
The stage- and subgroup-specific impact of non-HLA polymorphisms on preclinical type 1 diabetes progression
Vandewalle, J., Desouter, A. K., Van der Auwera, B. J., Chapaza, K. B., Nobels, F., Abrams, P., Lebrethon, M. C., Lapauw, B., Keymeulen, B., Gorus, F. K., Van de Casteele, M. & the Belgian Diabetes Registry, 15 Feb 2025, In: Heliyon. 11, 3, 12 p., e42156.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)3 Downloads (Pure) -
CTLA4, SH2B3 and CLEC16A diversely affect the progression of early islet autoimmunity in relatives of type 1 diabetes patients
Vandewalle, J., Desouter, A. K., Van der Auwera, B. J., Tenoutasse, S., Gillard, P., De Block, C., Keymeulen, B., Gorus, F. K., Van de Casteele, M. & Belgian Diabetes Registry, 24 Mar 2023, In: Clinical and Experimental Immunology. 211, 3, p. 224-232 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)70 Downloads (Pure)
Datasets
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Metabolomics data - "Chemogenetic astrocyte modulation reduces spontaneous hippocampal discharges and metabolite changes in an epilepsy mouse model"
Nestor, L. (Creator), Van Den Herrewegen, Y. (Creator), Dyer, M. (Creator), Bossuyt, J. (Creator), Hendrix, E. (Creator), Buckinx, A. (Creator), Bournons, S. (Creator), Viaene, J. (Creator), Vander Heyden, Y. (Creator), Van De Casteele, M. (Creator), Van Eeckhaut, A. (Creator), Smolders, I. (Creator) & De Bundel, D. (Creator), Zenodo, 2025
Dataset
Prizes
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European Association for the Study of Diabetes (EASD)
Van De Casteele, M. (Recipient), 1 Jan 2011
Prize: Fellowship awarded competitively
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Optimizing CAR-T Cell Therapy for Multiple Myelomaby Exploiting the Advantageous Properties of VHHAntigen-Binding Domains (Event)
Hanssens, H. (Speaker), Stijlemans, B. (Jury), kerre, T. (Jury), Raes, G. (Jury), De Becker, A. (Jury), De Munter, S. (Jury), Van De Casteele, M. (Chair), Devoogdt, N. (Supervisor), Breckpot, K. (Supervisor) & De Veirman, K. (Supervisor)
10 Sept 2024Activity: Membership › Member of PhD committee
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In situ PCR
Van De Casteele, M. (Member)
12 Aug 1997 → 30 Aug 1997Activity: Other › Research and Teaching at External Organisation
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Isolatie en groei van hyperthermofiele anaërobe prokaryoten
Van De Casteele, M. (Member)
1 Dec 1989 → 29 Dec 1989Activity: Other › Research and Teaching at External Organisation
Thesis
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Assessment of type 1 diabetes-associated human leukocyte antigen genotypes by nanopore sequencing
Kurti, E. ((PhD) Student), Van De Casteele, M. (Co-promotor) & Van Der Auwera, B. (Promotor), 7 Sept 2022Student thesis: Master's Thesis
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Beta-cell death in Type 1 Diabetes: How can we make stronger beta-cells?
Callewaert, H. ((PhD) Student), Van De Casteele, M. (Jury), Proost, P. (Jury), Cueppens, J. (Jury), Matthys, P. (Jury), Hellings, P. (Jury), Dotta, F. (Jury), Gysemans, C. (Co-promotor) & Mathieu, C. (Promotor), 2008Student thesis: Doctoral Thesis
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Cyclic AMP-dependent signal transduction leading to mitogenesis in thyroid. Implication of the mammalian target of rapamycin (mTOR)
Blanquaert, S. ((PhD) Student), Van De Casteele, M. (Jury) & Roger, P. (Promotor), 2010Student thesis: Doctoral Thesis
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Effect of genes IL27 and RNLS on progression of islet autoimmunity in type 1 diabetes
Mannaerts, H. R. ((PhD) Student) & Van De Casteele, M. (Promotor), 2024Student thesis: Master's Thesis
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Effect of polymorphisms in CTLA4 on progression of subclinical type 1 diabetes
Al-Kazzaz, A. S. ((PhD) Student) & Van De Casteele, M. (Promotor), Vandewalle, J. (Advisor), 2024Student thesis: Master's Thesis